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| 1 | Multigene editing via CRISPR/Cas9 guided by a single-sgRNA seed in Arabidopsis显示文摘We report that a solo single-guide RNA(sg RNA) seed is capable of guiding Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR)/CRISPRàassociated 9(CRISRP/Cas_9) to simultaneously edit multiple genes At RPL_(10)A, At RPL_(10)B and At RPL_(10)C in Arabidopsis. Our results also demonstrate that it is possible to use CRISPR/Cas_9 technology to create At RPL_(10) triple mutants which otherwise cannot be generated by conventional genetic crossing. Compared to other conventional multiplex CRISPR/Cas systems, a single sg RNA seed has the advantage of reducing off-target gene-editing. Such a gene editing system might be also applicable to modify other homologous genes, or even less-homologous sequences for multiple gene-editing in plants and other organisms. | Zhiming Yu Qiyuan Chen Weiwei Chen Xian Zhang Fengling Mei Pengcheng Zhang Mei Zhao Xiaohong Wang Nongnong Shi Stephen Jackson Yiguo Hong | 2018 | Journal of Integrative Plant Biology2018，60，5： | 10 |
| 2 | The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice显示文摘 | Premysl Bercik Emmanuel Denou Josh Collins Wendy Jackson Jun Lu Jennifer Jury Yikang Deng Patricia Blennerhassett Joseph Macri Kathy D. McCoy Elena F. Verdu Stephen M. Collins | 2011 | Gastroenterology2011，，2： | 2 |
| 3 | Risk factor management and depression post-stroke: The value of an integrated model of care显示文摘 | Jacques Joubert Chris Reid Lynette Joubert David Barton Denise Ruth David Jackson John O’. Sullivan Stephen M. Davis | 2005 | Journal of Clinical Neuroscience2005，，1： | 2 |
| 4 | PVX介导拟南芥Flowering locusT诱导烟草开花研究显示文摘为研究拟南芥Flowering locus T(FT)基因在开花诱导过程中的重要生物功能,本研究用RT-PCR方法,从拟南芥野生型(WS)中得到全长FT序列,采用Potato Virus X(PVX)野生型病毒构建载体,将全长FT基因连接到PVX第5个阅读框架即Coat Protein(CP)编码序列之前,经体外转录成PVX-FT病毒RNA,人工感染短日照烟草Maryland mommath,成功诱导短日照烟草在长日照条件下开花。 | 刘旭新 Stephen Jackson 李春阳 | 2009 | 核农学报2009，23，1： | 2 |
| 5 | Destination Life Cycle : the Isle of Man Case Study 显示文摘 | Chris Cooper Stephen Jackson | 1989 | Annals of Tourism Research1989，16，3： | 1 |
| 6 | Agonist-stimulated synthesis of phosphatidylinositol (3,4,5)-triphosphate:a new intracellular signaling system?显示文摘 | JACKSON T R HAWKINS P T | 1993 | Biochim Biophys Acta1993，1179，1： | 1 |
| 7 | The role of microRNAs in the control of flowering time显示文摘 | Eleonora Spanudakis Stephen Jackson | 2014 | Journal of Experimental Botany2014，6，52： | 1 |
| 8 | 'Action binding' :Dynamic interactions between vision and touch 显示文摘 | Jackson Stephen R | 2001 | Trends in Cognitive Sciences2001，5，12： | 1 |
| 9 | Pollen dispersal models in Quaternary plant ecology: Assumptions, parameters, and prescriptions显示文摘 | Stephen T. Jackson Mark E. Lyford | 1999 | The Botanical Review1999，，1： | 1 |
| 10 | The climatic impacts of land surface change and carbon management, and the implications for climate-change mitigation policy显示文摘 | Gregg Marland Roger A. Pielke Mike Apps Roni Avissar Richard A. Betts Kenneth J. Davis Peter C. Frumhoff Stephen T. Jackson Linda A. Joyce Pekka Kauppi John Katzenberger Kenneth G. MacDicken Ronald P. Neilson John O. Niles Dev dutta S. Niyogi Richard J. N | 2003 | Climate Policy2003，，2： | 1 |
| 11 | Destination Life Cycle:the Isle of Man Case Study 显示文摘 | Chris Cooper Stephen Jackson | 1989 | Annals of Tourism Research1989，，16： | 1 |
| 12 | Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice显示文摘 | Premysl Bercik Elena F. Verdu Jane A. Foster Joseph Macri Murray Potter Xiaxing Huang Paul Malinowski Wendy Jackson Patricia Blennerhassett Karen A. Neufeld Jun Lu Waliul I. Khan Irene Corthesy–Theulaz Christine Cherbut Gabriela E. Bergonzelli Stephen M. | 2010 | Gastroenterology2010，，6： | 1 |
| 13 | The role of microRNAs in the control of flowering time显示文摘 | Elenonora Spanudakis Stephen Jackson | 2014 | Journal of Experimental Botany2014，65，2： | 1 |
| 14 | Destination life cycle: the Isle of Man case study显示文摘 | Chris Cooper Stephen Jackson | 1989 | Annals of Tourism Research1989，16，： | 1 |
| 15 | A study of SSM/I-derived co- lumnar water vapor over the global oceans 显示文摘 | JACKSON D L STEPHENS G L | 1995 | J Atmos Sci1995，8，： | 1 |
| 16 | Mechanisms of Action of In-traresical Bacille Calmette-Guérin:Local Immune Mechanisms显示文摘 | Stephen P Andrew M Jackson SJ | 2000 | Clini-cal Infectious Diseases2000，31，： | 1 |
| 17 | Cloning and expression analysis of a gene that shows developmental regulation upon tuberization in potato显示文摘 | Stephen Jackson Jordi Gascón Esther Carrera Elena Monte Salomé Prat | 1997 | Plant Molecular Biology1997，，1： | 1 |
| 18 | Diabetic retinopathy screening and monitoring of early stage disease in general practice: Design and methods显示文摘 | Deborah A. Askew Lisa Crossland Robert S. Ware Stephen Begg Peter Cranstoun Paul Mitchell Claire L. Jackson | 2012 | Contemporary Clinical Trials2012，，5： | 1 |
| 19 | The DNA- damage response in human biology and diseaze 显示文摘 | Stephen P Jackson Jiri Bartek | 2009 | Nature2009，461，22： | 1 |
| 20 | A means to a DNA end:The many roles of Ku显示文摘 | Jessica A Downs Stephen P Jackson | 2004 | Molecular Cell Biology2004，5，： | 1 |
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