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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Physician-level variation in the diagnosis of myocardial infarction and the use of angiography among veterans with elevated troponin显示文摘Background:Cardiac troponin assays have improved the ability to detect myocardial damage.However,ascertaining whether troponin elevation is due to myocardial infarction(MI) or secondary to another process can be challenging.Our aim is to evaluate provider-level variation in the diagnosis of MI and the use of invasive coronary angiography(ICA) among patients with undifferentiated elevations in cardiac troponin.Methods:We analyzed data from all patients with elevated troponin levels in a single Veterans Affairs(VA) Medical Center between 2006 and 2007.One of several cardiologists prospectively evaluated each patient's presentation and course of care.We compared the frequency of MI diagnosis and ICA use between physicians using univariate odds ratios(OR).Results:Among 761 patients,34.0% were diagnosed with MI and 25.9% underwent ICA.The unadjusted rates of MI(23.9% to 56.7%,P=0.02) and ICA(17.3% to 73.3%,P<0.001) differed between physicians.Comparing the patient cohorts for each physician,baseline characteristics were similar except for chest pain.In multivariate regression,factors associated with the use of cardiac ICA included an abnormal electrocardiograph(ECG)(OR=1.89,P=0.014),level of troponin(OR=1.71,P=0.004),chest pain(OR=8.60,P<0.001),and care by non-VA physicians(OR=4.45,P=0.006).One physician had a lower ICA use(OR=0.56,P=0.017).In multivariate regression of MI,no physician-level variation was observed.Conclusion:Among patients with elevated troponin,the likelihood of being diagnosed with MI and undergoing ICA is dependent on their clinical presentation.After adjustment,physician-level variation in care was observed for the use of ICA,but not for the diagnosis of MI. | David E.Winchester Nayan Agarwal Lucas Burke Steven Bradley Tatiana Schember Carsten Schmalfuss | 2016 | Journal of Medical Colleges of PLA(China)2016，31，3： | 2 |
| 3 | Surgical Management of Early-Stage Hepatocellular Carcinoma: Resection or Transplantation?显示文摘 | Emily C. Bellavance Kimberly M. Lumpkins Gilles Mentha Hugo P. Marques Lorenzo Capussotti Carlo Pulitano Pietro Majno Paulo Mira Laura Rubbia-Brandt Alessandro Ferrero Luca Aldrighetti Steven Cunningham Nadia Russolillo Benjamin Philosophe Eduardo Barroso | 2008 | Journal of Gastrointestinal Surgery2008，，10： | 2 |
| 4 | Peginterferon and Ribavirin Treatment in African American and Caucasian American Patients With Hepatitis C Genotype 1显示文摘 | Hari S. Conjeevaram Michael W. Fried Lennox J. Jeffers Norah A. Terrault Thelma E. Wiley–Lucas Nezam Afdhal Robert S. Brown Steven H. Belle Jay H. Hoofnagle David E. Kleiner Charles D. Howell | 2006 | Gastroenterology2006，，2： | 2 |
| 5 | Immediat laparoscopic cholecystectomy for acute cholecystitis:no need to wait显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，192，6： | 1 |
| 6 | Immediate laparoscopic cholecystectomy for acute cholecystitis:no need to wait显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，92，6： | 1 |
| 7 | Immediate laparoscopic cholecystectomy for acute cholecystitis: no need to wait 显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，92，6： | 1 |
| 8 | Association study of 12 polymorphisms spanning the dopamine D2 receptor gene and clozapine treatment response in two treatment refractory/intolerant populations显示文摘 | Rudi Hwang Takahiro Shinkai Vincenzo Luca Daniel J. Müller Xingqun Ni Fabio Macciardi Steven Potkin Jeffrey A. Lieberman Herbert Y. Meltzer James L. Kennedy | 2005 | Psychopharmacology2005，，1： | 1 |
| 9 | Satellite based analysis of northern ET trends and associated changes in the regional water balance from 1983 to 2005显示文摘 | Ke Zhang John S. Kimball Qiaozhen Mu Lucas A. Jones Scott J. Goetz Steven W. Running | 2009 | Journal of Hydrology2009，，1： | 1 |
| 10 | Immediate laparoseopic cholecys- tectomy for acute eholeeystitis: No need to wait显示文摘 | Stevens KA Chi A Lucas LG | 2006 | Am J Surg2006，92，6： | 1 |
| 11 | Immediate laparoscopic chole- cystectomy for acute cholecystitis: no need to wait 显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，192，： | 1 |
| 12 | Cardiac Hemodynamic and Coronary Angiographic Characteristics of Patients Being Evaluated for Liver Transplantation显示文摘 | Susan D. Tiukinhoy-Laing Joseph S. Rossi Melike Bayram Leonardo De Luca Sameer Gafoor Andres Blei Steven Flamm Charles J. Davidson Mihai Gheorghiade | 2006 | The American Journal of Cardiology2006，，2： | 1 |
| 13 | Immediate laparoscopic cholecystectomy for acute cholecystitis:no need to wait显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，192，6： | 1 |
| 14 | Virtual Reality Training Improves Simulated Laparoscopic Surgery Performance in Laparoscopy Naivemedical Students 显示文摘 | Lucas Steven Tuncel Altug Bensalah Karim | 2008 | Journal of Endourology2008，22，5： | 1 |
| 15 | Physician surveys to assess customary care in medical malpractice cases显示文摘 | Dr. Arthur Hartz MD PhD Joshua Lucas BS Timothy Cramm MD Michael Green JD Suzanne Bentler MS John Ely MD MSPH Steven Wolfe MD Paul James MD | 2002 | Journal of General Internal Medicine2002，，7： | 1 |
| 16 | Pure natural orifice transluminal endoscopic surgery (NOTES) cholecystectomy显示文摘 | Marc Bessler Andrew A. Gumbs Luca Milone John C. Evanko Peter Stevens Dennis Fowler | 2010 | Surgical Endoscopy2010，，9： | 1 |
| 17 | Transvaginal laparoscopic cholecystectomy: laparoscopically assisted显示文摘 | Marc Bessler Peter D. Stevens Luca Milone Nancy J. Hogle Evren Durak Dennis Fowler | 2008 | Surgical Endoscopy2008，，7： | 1 |
| 18 | PEGylated chitosan derivatives: Synthesis, characterizations and pharmaceutical applications显示文摘 | Luca Casettari Driton Vllasaliu Enzo Castagnino Snjezana Stolnik Steven Howdle Lisbeth Illum | 2011 | Progress in Polymer Science2011，，5： | 1 |
| 19 | Immediate laparoscopic cholecystectomy for acute cholecystitis: no need to wait 显示文摘 | Stevens KA Chi A Lucas LC | 2006 | Am J Surg2006，92，6： | 1 |
| 20 | Small-Scale Household Biogas Digesters as a Viable Option for Energy Recovery and Global Warming Mitigation--Vietnam Case Study显示文摘 | Thanh Ba Ho Timothy Kilgour Roberts Steven Lucas | 2015 | Journal of Agricultural Science and Technology(A)2015，5，6： | 0 |
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