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| 1 | Wheat breeding history reveals synergistic selection of pleiotropic genomic sites for plant architecture and grain yield显示文摘Diversity surveys of crop germplasm are important for gaining insights into the genomic basis for plant architecture and grain yield improvement,which is still poorly understood in wheat.In this study,we exome sequenced 287 wheat accessions that were collected in the past 100 years.Population genetics analysis identified that 6.7%of the wheat genome falls within the selective sweeps between landraces and cultivars,which harbors the genes known for yield improvement.These regions were asymmetrically distributed on the A and B subgenomes with regulatory genes being favorably selected.Genome-wide association study(GWAS)identified genomic loci associated with traits for yield potential,and two underlying genes,TaARF12 encoding an auxin response factor and TaDEP1 encoding the G-proteinγ-subunit,were located and characterized to pleiotropically regulate both plant height and grain weight.Elite single-nucleotide haplotypes with increased allele frequency in cultivars relative to the landraces were identified and found to have accumulated over the course of breeding.Interestingly,we found that TaARF12 and TaDEP1 function in epistasis with the classical plant height Rht-1 locus,leading to propose a“Green Revolution”-based working model for historical wheat breeding.Collectively,our study identifies selection signatures that fine-tune the gibberellin pathway during modern wheat breeding and provides a wealth of genomic diversity resources for the wheat research community. | Aili Li Chenyang Hao Zhenyu Wang Shuaifeng Geng Meiling Jia Fang Wang Xiang Han Xingchen Kong Lingjie Yin Shu Tao Zhongyin Deng Ruyi Liao Guoliang Sun Ke Wang Xingguo Ye Chengzhi Jiao Hongfeng Lu Yun Zhou Dengcai Liu Xiangdong Fu Xueyong Zhang Long Mao | 2022 | Molecular Plant2022，15，3： | 4 |
| 2 | Determination of carcinoembryonic antigen using a novel amperometric enzyme-electrode based on layer-by-layer assembly of gold nanoparticles and thionine显示文摘Electrochemical sensing of carcinoembryonic antigen(CEA)on a gold electrode modified by the se- quential incorporation of the mediator,thionine(Thi),and gold nanoparticles(nano-Au),through co- valent linkage and electrostatic interactions onto a self-assembled monolayer configuration is de- scribed in this paper.The enzyme,horseradish peroxidase(HRP),was employed to block the possible remaining active sites of the nano-Au monolayer,avoid the non-specific adsorption,instead of bovine serum albumin(BSA),and amplify the response of the antigen-antibody reaction.Electrochemical ex- periments indicated highly efficient electron transfer by the imbedded Thi mediator and adsorbed nano-Au.The HRP kept its activity after immobilization,and the studied electrode showed sensitive response to CEA and high stability during a long period of storage.The working range for the system was 2.5 to 80.0 ng/mL with a detection limit of 0.90 ng/mL.The model membrane system in this work is a potential biosensor for mimicking the other immunosensor and enzyme sensor. | YUAN Ruo ZHUO Ying CHAI YaQin ZHANG Ying SUN AiLi | 2007 | Science China Chemistry2007，50，1： | 3 |
| 3 | Evaluation of alternate cooling and heating for tumor treatment显示文摘 | Sun Jianqi Zhang Aili Xu Lisa X | 2008 | International Journal of Heat and Mass Transter2008，，51： | 1 |
| 4 | Group-selective enrichment and determination of pyrethroid insecticides in aquaculture seawater via molecularly imprinted solid phase extraction coupled with gas chromatography- electron capture detection 显示文摘 | SHI Xizhi LIU Jinghua SUN Aili | 2012 | Journal of Chromatography A2012，1227，： | 1 |
| 5 | Molecular evolution of two duplicated CDPK genes CPK7 and CPK12 in grass species: A case study in wheat ( Triticum aestivum L.)显示文摘 | Shuaifeng Geng Yongliang Zhao Lichuan Tang Rongzhi Zhang Minghui Sun Hanzi Guo Xiuying Kong Aili Li Long Mao | 2011 | Gene2011，，2： | 1 |
| 6 | Group-selec tive Enrichment and Determination of Pyrethroid Insecticides in Aquaculture Seawater via Molecu- larly Imprinted Solid Phase Extraction Coupled with Gas Chromatography-electron Capture Detec- tion 显示文摘 | Shi Xizhi Liu Jinghua Sun Aili | 2012 | Journal of Chromatography A2012，1227，： | 1 |
| 7 | A highly sensitive non-enzymatic glucose sensor based on nickel and multi-walled carbon nanotubes nanohybrid films fabricated by one-step co-electrodeposition in ionic liquids显示文摘 | Aili Sun Jianbin Zheng Qinglin Sheng | 2012 | Electrochimica Acta2012，，： | 1 |
| 8 | Xu, Evaluation of alternative cooling and heating for tumor treatment 显示文摘 | Jianqi Sun Aili Zhang Lisa X | 2008 | International Journal of Heat and Mass Transfer2008，51，： | 1 |
| 9 | Mobile decision-tree tool technology as a means to detect wildlife crimes and build enforcement networks显示文摘 | Heidi E. Kretser Ramacandra Wong Scott Roberton Carrianne Pershyn JianMing Huang Fuping Sun Aili Kang Peter Zahler | 2014 | Biological Conservation2014，，： | 1 |
| 10 | Efficient User Preferences-Based Top-k Skyline Using MapReduce显示文摘 | Linlin Ding Xiao Zhang Mingxin Sun Aili Liu Baoyan Song | 2018 | 国际计算机前沿大会会议论文集2018，，1： | 1 |
| 11 | The soft glumes of common wheat are sterile-lemmas as determined by the domestication gene Q显示文摘The Q gene in common wheat encodes an APETALA2(AP2) transcription factor that causes the free threshing attribute. Wheat spikelets bearing several florets are subtended by a pair of soft glumes that allow free liberation of seeds. In wild species, the glumes are tough and rigid,making threshing difficult. However, the nature of these 'soft glumes', caused by the domestication allele Q is not clear. Here, we found that over expression of Q in common wheat leads to homeotic florets at glume positions. We provide phenotypic, microscopy, and marker genes evidence to demonstrate that the soft glumes of common wheat are in fact lemma-like organs, or so-called sterile-lemmas. By comparing the structures subtending spikelets in wheat and other crops such as rice and maize, we found that AP2 genes may play conserved functions in grasses by manipulating vestigial structures, such as floret-derived soft glumes in wheat and empty glumes in rice. Conversion of these seemingly vegetative organs to reproductive organs may be useful in yield improvement of crop species. | Gaoyuan Song Guoliang Sun Xingchen Kong Meiling Jia Ke Wang Xingguo Ye Yun Zhou Shuaifeng Geng Long Mao Aili Li | 2019 | The Crop Journal2019，7，1： | 1 |
| 12 | Characterisation and application of molecularly imprinted polymers for group-selective recognition of antibiotics in food samples 显示文摘 | Xizhi Shi Suquan Song Aili Sun | 2012 | Analyst2012，137，14： | 1 |
| 13 | A tris(2,2′-bipyridyl)cobalt(III)-bovine serum albumin composite membrane for biosensors显示文摘 | Ying Zhuo Ruo Yuan Yaqin Chai Aili Sun Ying Zhang Jiuzhi Yang | 2006 | Biomaterials2006，，31： | 1 |
| 14 | Water Consumption and Maize Yield for Alternative Furrow Irrigation in Western Heilongjiang Province显示文摘Aiming at less and un-uniform distribution rainfall problems, the serious draught in spring, low crop production and water efficiency in sandy soil area of Heilongjiang Province, the experiment of alternative furrow irrigation was conducted in Dumeng County in 2009. The purpose of the experiment was to find the water consumption law and its influence on maize yield. The results showed that the highest water consumption was during the heading stage and the highest daily consumption of water was during the filling stage. The stimulation effect of alternative furrow irrigation on yield was obvious in the appropriate irrigation level. The best irrigation pattern for the highest yield was as follows: the seedling stage was 325 m3 ? hm-2; the jointing stage was 400 m3 ? hm-2; and the filling stage was 288 m3 ? hm-2. The water consumption during each growing period was that the seedling was 38.85 mm; the jointing was 108.11 mm; the heading was 124.39 mm; the filling was 88.96 mm; the milk was 60.21 mm; and the harvesting was 47.89 mm. | SUN Aili LI Yuexing WEI Yongxia | 2010 | Journal of Northeast Agricultural University(English Edition)2010，17，4： | 0 |
| 15 | Method and Application of Endogenous Neurotransmitter Regulation Theory显示文摘Objective:Verification and application of the theory of brain cell activation.Methods:Applying transcranial magnetoelectric encephalopathy treatment instrument to the treatment of neurodegenerative disease,including but not limited to:Parkinson’s disease and Alzheimer’s disease.Results:Transcranial magnetoelectric encephalopathy treatment instrument,its double-center,randomized,double-blind clinical trial has been carried out at the national clinical trial base,it proves that the instrument is safe and effective.This instrument is especially suitable for the treatment of the following diseases:(1)it is suitable for the treatment of mild to moderate Parkinson’s disease and can significantly improve resting tremor,rigidity,bradykinesia in patients with Parkinson’s disease and other symptoms;(2)it is suitable for the treatment of mild and moderate Alzheimer’s disease and vascular dementia and can improve the mental state,cognitive behavior and self-care ability of daily life;(3)it is suitable for the treatment of mild to moderate depression and can obviously improve the main symptoms of depression,sleep disorder,anxiety and so on;(4)it is suitable for the treatment of cerebral apoplexy sequelae,cerebrovascular dementia and brain atrophy,and it can activate the brain cells in the state of inhibition and mobilize the potential energy of the brain.Conclusions:The theory of brain cell activation is applicable to encephalopathy and not limited to encephalopathy,according to this theory,the subject of“physical disease science”can be created. | Zuodong Sun Wuyi Sun Aili Wang Wenhua Wang | 2019 | Journal of US-China Medical Science2019，16，5： | 0 |
| 16 | Assessment of alternated cooling and heating treatment by US combined CEUS in the VX2 rabbit liver tumor model显示文摘Inoperable liver tumors are often treated by thermal ablation that destroys the tumor in situ and spares the adjacent hepatic tissue.Thermal–physical treatment has many advantages,but treatment by freezing or heating alone has some limitations.By taking the advantages and disadvantages of cryosurgery and thermotherapy into consideration,a new thermal technique that combines cryosurgery and radio frequency ablation has been proposed,thereby overcoming the disadvantages of each treatment strategy and improving therapeutic outcomes.This new approach remains to be systematically studied in the liver;therefore,this study was performed to estimate survival after alternated cooling and heating ablation therapy in a VX2 rabbit liver tumor model.Sixteen days after VX2 carcinoma implantation into the rabbit liver,tumors were treated with alternated cooling and heating ablation therapy.Rabbits were monitored for 6 months after treatment and assessed with ultrasound(US)and computed tomography at 1,7,14,and 30 days posttreatment.Untreated tumor-bearing animals served as the control group.Our results show that alternate freezing and heating ablation therapy resulted in a good recovery of VX2 rabbits.Compared with the control group,treated rabbits lived significantly longer(P\0.05),with 70%of treated animals surviving to 196 days posttreatment without metastasis or recurrence,while none of the controls did so.There was no local recurrence in the treatment group.All rabbits in the control group developed metastasis,while metastasis was only observed in 30% of treated rabbits.These results suggest that alternate cooling and heating ablation therapy can prolong the survival time of rabbits with VX2 liver tumors and is an effective method for tumor therapy.Furthermore,we also showed in this model that contrast enhanced US is a valid follow-up approach to assess treatment effectiveness. | Cong Wei E.Shen Di Sun Aili Zhang Jianqi Sun Bing Hu | 2014 | Chinese Science Bulletin2014，59，9： | 0 |
| 17 | Surface reconstruction,doping and vacancy engineering to improve the overall water splitting of CoP nanoarrays显示文摘Development of a general regulatory strategy for efficient overall water splitting remains a challenging task.Herein,a simple,costfairness,and general fluorination strategy is developed to realize surface reconstruction,heteroatom doping,and vacancies engineering over cobalt phosphide(CoP)for acquiring high-performance bifunctional electrocatalysts.Specifically,the surface of CoP nanoarrays(NAs)becomes rougher,meanwhile F doped into CoP lattice and creating amounts of P vacancies by fluorination,which caused the increase of active sites and regulation of charge distribution,resulting the excellent electrocatalyst performance of F-CoP NAs/copper foam(CF).The optimized F-CoP NAs/CF delivers a lower overpotential of only 35 mV at 10 mA·cm^(−2)for hydrogen evolution reaction(HER)and 231 mV at 50 mA·cm^(−2)for oxygen evolution reaction(OER),and the corresponding overall water splitting requires only 1.48 V cell voltage at 10 mA·cm^(−2),which are superior to the most state-of-theart reported electrocatalysts.This work provides an innovative and feasible strategy to construct efficient electrocatalysts. | Yongkai Sun Wenyuan Sun Lihong Chen Alan Meng Guicun Li Lei Wang Jianfeng Huang Aili Song Zhenhui Zhang Zhenjiang Li | 2023 | Nano Research2023，16，1： | 0 |
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