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17篇 您的检索式:作者名="Susan W F"
    题名 作者 年代 出处 被引量
1Reaction synthesis of Ni-Al-based particle composite coatings 显示文摘SUSAN D F MISIOLEK W Z MARDER A R 2001Metall Mater Trans2001,32,:1
2Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia显示文摘Jeremy W Fox Edward D Lamperti Yaman Z Ek?io?lu Susan E Hong Yuanyi Feng Donna A Graham Ingrid E Scheffer William B Dobyns Betsy A Hirsch Rodney A Radtke Samuel F Berkovic Peter R Huttenlocher Christopher A Walsh 1998Neuron1998,,6:1
3Activation of insulin-reactive CD8 T-cells for development of autoim-mune diabetes 显示文摘SUSAN F W KHAI S L GWEN S 2009Diabetes2009,58,5:1
4Clinical measurement of sit-to-stand performance in people with balance disorders: Validity of data for the five-times-sit-to-stand test 显示文摘Susan L W Dina M W Gregory F M 2005Physical Therapy2005,85,11:1
5Reaction synthesis of Ni-Al-hased particle composite 显示文摘Susan D F Misiolek W Z Marder A R 2001Metall Mater Trans A2001,32,:1
6The mean structure of the Mindanao current at 8°N 显示文摘SUSAN W ERIC F JOHN T 1995Journal of Geophysical Research1995,9,18:1
7Development of an enzyme - linked immunosorbent assay for alachlor and its application to the analysis of environmental water samples 显示文摘Paul C C F Stephen J W Susan R H 1990J Agric Food Chem1990,38,1:1
8CC4-03: The Use of Administrative Data and Natural Language Processing to Estimate the Incidence of Statin-related Rhabdomyolysis显示文摘James F Susan H Noel W 2012Clin Med Res2012,10,8:1
9Contemporaneous fluctuations in T cell responses to persistent herpes virus infections显示文摘Tania C Chrysa F Susan W 2005Eur J Immunol2005,35,:1
10Rational de- sign of α-Helical antimicrobial peptides with enhanced activities and specificity/therapeutic index显示文摘Yuxin Chen Colin T M Susan W F 2005J Biol Chem2005,280,12:1
11Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells 显示文摘MICHAEL W P LORA W F SUSAN P P 1998J Lab Clin Med1998,132,6:1
12Reaction synthesis of Ni-Al-based particle composite coatings显示文摘 Misiolek W Z Mader A R 2001Metallurgical and Materiala Transactions A2001,32,:1
13Indexing by Latent Semantic Analysis 显示文摘SCOTT D SUSAN T D GEORGE W F 1990Journal of the American Society for Information Science1990,41,6:1
14Reaction synthesis of Ni-Al-based particle composite coatings 显示文摘Susan D F Misiolek W Z Marder A R 2001Metallurgical and Materials Transactions A2001,32,2:1
15P/M titanium matrix composite: From war to fun & games显示文摘SUSAN M A PAUL F W 1996Science and Technology1996,,:1
16Comparisons of Causes of Death and Mortality Rates Among HIV-Infected Persons: Analysis of the Pre-, Early, and Late HAART (Highly Active Antiretroviral Therapy) Eras显示文摘Nancy F Crum Robert H Riffenburgh Scott Wegner Brian K Agan Sybil A Tasker Katherine M Spooner Adam W Armstrong Susan Fraser Mark R Wallace 2006JAIDS Journal of Acquired Immune Deficiency Syndromes2006,,2:1
17Competing risks of death in younger and older postmenopausal breast cancer patients显示文摘AIM: To show a new paradigm of simultaneously testing whether breast cancer therapies impact other causes of death. METHODS: MA.14 allocated 667 postmenopausal women to 5 years of tamoxifen 20 mg/daily ± 2 years of octreotide 90 mg, given by depot intramuscular injections monthly. Event-free survival was the primary endpoint of MA.14; at median 7.9 years, the tamoxifen+octreotide and tamoxifen arms had similar event-free survival(P = 0.62). Overall survival was a secondary endpoint, and the two trial arms also had similar overall survival(P = 0.86). We used the median 9.8 years follow-up to examine by intention-to-treat, the multivariate time-to-breast cancer-specific(Br Ca) and other cause(OC) mortality with log-normal survival analysis adjusted by treatment and stratification factors. We tested whether baseline factors including Insulin-like growth factor 1(IGF1), IGF binding protein-3, C-peptide, body mass index, and 25-OH vitamin D were associated with(1) all cause mortality, and if so; and(2) cause-specific mortality. We also fit step-wise forward cause-specific adjusted models.RESULTS: The analyses were performed on 329 patients allocated tamoxifen and 329 allocated tamoxifen+octreotide. The median age of MA.14 patients was 60.1 years: 447(82%) < 70 years and 120(18%) ≥ 70 years. There were 170 deaths: 106(62.3%) BrC a; 55(32.4%) OC, of which 24 were other malignancies, 31 other causes of death; 9(5.3%) patients with unknown cause of death were excluded from competing risk assessments. BrC a and OC deaths were not significantly different by treatment arm(P = 0.40): tamoxifen patients experienced 50 BrC a and 32 OC deaths, while tamoxifen + octreotide patients experienced 56 Br Ca and 23 OC deaths. Proportionately more deaths(P = 0.004) were from BrC a for patients< 70 years, where 70% of deaths were due to Br Ca, compared to 54% for those ≥ 70 years of age. The proportion of deaths from OC increased with increasing body mass index(BMI)(P = 0.02). Higher pathologic T and N were associated with more BrC a deaths(P < 0.0001 and 0.002, respectively). The cumulative hazard plot for Br Ca and OC mortality indicated the concurrent accrual of both types of death throughout followup, that is the existence of competing risks of mortality. MA.14 therapy did not impact mortality(P = 0.77). Three baseline patient and tumor characteristics were differentially associated with cause of death: older patients experienced more OC(P = 0.01) mortality; patients with T1 tumors and hormone receptor positive tumors had less BrC a mortality(respectively, P = 0.01, P = 0.06). Additionally, step-wise cause-specific models indicated that patients with node negative disease experienced less BrC a mortality(P = 0.002); there was weak evidence that, lower C-peptide(P = 0.08) was associated with less BrC a mortality, while higher BMI(P = 0.01) was associated with worse OC mortality.CONCLUSION: We demonstrate here a new paradigm of simultaneous testing of therapeutics directed at multiple diseases for which postmenopausal women are concurrently at risk. Octreotide LAR did not significantly impact breast cancer or other cause mortality, although different baseline factors influenced type of death.Judy-Anne W Chapman Kathleen I Pritchard Paul E Goss James N Ingle Hyman B Muss Susan F Dent Ted A Vandenberg Brian Findlay Karen A Gelmon Carolyn F Wilson Lois E Shepherd Michael N Pollak 2014World Journal of Clinical Oncology2014,5,5:0
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