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| 1 | ASPP Proteins Specifically Stimulate the Apoptotic Function of p53显示文摘 | Yardena Samuels-Lev Daniel J. O’Connor Daniele Bergamaschi Giuseppe Trigiante Jung-Kuang Hsieh Shan Zhong Isabelle Campargue Louie Naumovski Tim Crook Xin Lu | 2001 | Molecular Cell2001，，4： | 1 |
| 2 | Novel diamond shuttle to deliver flexible neural probe with reduced tissue compression显示文摘The ability to deliver flexible biosensors through the toughest membranes of the central and peripheral nervous system is an important challenge in neuroscience and neural engineering.Bioelectronic devices implanted through dura mater and thick epineurium would ideally create minimal compression and acute damage as they reach the neurons of interest.We demonstrate that a three-dimensional diamond shuttle can be easily made with a vertical support to deliver ultra-compliant polymer microelectrodes(4.5-µm thick)through dura mater and thick epineurium.The diamond shuttle has 54%less cross-sectional area than an equivalently stiff silicon shuttle,which we simulated will result in a 37%reduction in blood vessel damage.We also discovered that higher frequency oscillation of the shuttle(200Hz)significantly reduced tissue compression regardless of the insertion speed,while slow speeds also independently reduced tissue compression.Insertion and recording performance are demonstrated in rat and feline models,but the large design space of these tools are suitable for research in a variety of animal models and nervous system targets. | Kyounghwan Na Zachariah J.Sperry Jiaao Lu Mihaly Voroslakos Saman S.Parizi Tim M.Bruns Euisik Yoon John P.Seymour | 2020 | Microsystems & Nanoengineering2020，6，1： | 1 |
| 3 | Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting显示文摘 | Mathias Ehrich Cosmin Deciu Tricia Zwiefelhofer John A. Tynan Lesley Cagasan Roger Tim Vivian Lu Ron McCullough Erin McCarthy Anders O.H. Nygren Jarrod Dean Lin Tang Don Hutchison Tim Lu Huiquan Wang Vach Angkachatchai Paul Oeth Charles R. Cantor Allan Bo | 2011 | American Journal of Obstetrics and Gynecology2011，，3： | 1 |
| 4 | Estimating the impact of conservation measures on strearo-flow regime in catchments of the Loess Plateau, China显示文摘 | Xingmin Mu Lu Zhang Tim R McVicar | 2007 | Hydrological Progress2007，21，16： | 1 |
| 5 | Removal of diesel particulate matter (DPM) in a tubular wet electrostatic precipitator显示文摘 | Phirun Saiyasitpanich Tim C. Keener Soon-Jai Khang Mingming Lu | 2007 | Journal of Electrostatics2007，，10： | 1 |
| 6 | Managing Passenger Behavioral Intention: an Integrated Framework for Service Quality, Satisfaction, Perceived Value, and Switching Barriers显示文摘 | WILLIAM JEN RUNGTING TU TIM LU | 2011 | Transportation2011，38，2： | 1 |
| 7 | Identification of a regulatory autophosphorylation site in the serine–threonine kinase RIP2显示文摘 | Marion Dorsch Anlai Wang Hong Cheng Chafen Lu Andrew Bielecki Kathryn Charron Karl Clauser Hong Ren Roberto D. Polakiewicz Tom Parsons Ping Li Tim Ocain Yajun Xu | 2006 | Cellular Signalling2006，，12： | 1 |
| 8 | Radiation Doses in Interventional Radiology Procedures: The RAD-IR Study Part I: Overall Measures of Dose显示文摘 | Donald L. Miller Stephen Balter Patricia E. Cole Hollington T. Lu Beth A. Schueler Michael Geisinger Alejandro Berenstein Robin Albert Jeffrey D. Georgia Patrick T. Noonan John F. Cardella James St. George Eric J. Russell Tim W. Malisch Robert L. Vogelzan | 2003 | Journal of Vascular and Interventional Radiology2003，，： | 1 |
| 9 | How Frequently Will the Persistent Heavy Rainfall over the Middle and Lower Yangtze River Basin in Summer 2020 Happen under Global Warming?显示文摘The middle and lower Yangtze River basin(MLYRB)suffered persistent heavy rainfall in summer 2020,with nearly continuous rainfall for about six consecutive weeks.How the likelihood of persistent heavy rainfall resembling that which occurred over the MLYRB in summer 2020(hereafter 2020PHR-like event)would change under global warming is investigated.An index that reflects maximum accumulated precipitation during a consecutive five-week period in summer(Rx35day)is introduced.This accumulated precipitation index in summer 2020 is 60%stronger than the climatology,and a statistical analysis further shows that the 2020 event is a 1-in-70-year event.The model projection results derived from the 50-member ensemble of CanESM2 and the multimodel ensemble(MME)of the CMIP5 and CMIP6 models show that the occurrence probability of the 2020PHR-like event will dramatically increase under global warming.Based on the Kolmogorov-Smirnoff test,one-third of the CMIP5 and CMIP6 models that have reasonable performance in reproducing the 2020PHR-like event in their historical simulations are selected for the future projection study.The CMIP5 and CMIP6 MME results show that the occurrence probability of the 2020PHR-like event under the present-day climate will be double under lower-emission scenarios(CMIP5 RCP4.5,CMIP6 SSP1-2.6,and SSP2-4.5)and 3-5 times greater under higher-emission scenarios(3.0 times for CMIP5 RCP8.5,2.9 times for CMIP6 SSP3-7.0,and 4.8 times for CMIP6 SSP5-8.5).The inter-model spread of the probability change is small,lending confidence to the projection results.The results provide a scientific reference for mitigation of and adaptation to future climate change. | Zi-An GE Lin CHEN Tim LI Lu WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 10 | Decomposition of vegetation cover into woody and herbaceous components using AVHRR NDVI time series显示文摘 | Hua Lu Michael R. Raupach Tim R. McVicar Damian J. Barrett | 2003 | Remote Sensing of Environment2003，，1： | 1 |
| 11 | Decomposition of vegetation cover into woody and herbaceous components using AVHRR NDVI time series显示文摘 | Lu Hua Michael R Raupach Tim R McVicar | 2003 | Remote Sensing of Environment2003，，86： | 1 |
| 12 | Using an improved electrostatic precipitator for poultry dust removal 显示文摘 | Ming Chai Mingming Lu Tim Keener | 2009 | Journal of Electrostatics2009，67，87： | 1 |
| 13 | Determination of polycyclic aromatic sulfur heterocycles in diesel particulate matter and diesel fuel by gas chromatography with atomic emission detection显示文摘 | Fuyan Liang Mingming Lu M. Eileen Birch Tim C. Keener Zifei Liu | 2006 | Journal of Chromatography A2006，，1： | 1 |
| 14 | Evaluation of the Madden-Julian oscillation in HiRAM显示文摘本研究评估了高分辨率大气环流模式HiRAM模拟的MJO.结果表明,HiRAM模拟的MJO东传很弱.我们通过计算整层积分的湿静力能(MSE)收支来诊断MJO东传模拟偏差的原因.结果发现,MSE倾向相对于MJO对流中心的纬向非对称分布很弱是导致东传模拟偏弱的原因,这主要是由MSE垂直平流和地表湍流通量的模拟偏差造成的.进一步研究表明,对流层上层MJO垂直环流结构的模拟偏差和MJO对流西侧的Rossby波环流偏强共同导致了模式的偏差.本研究中指出的MJO传播模拟偏差的原因与之前基于多模式结果的结论不同,这意味着要想了解特定模式的模拟偏差,有必要对该模式进行具体分析. | Jie Jiang Lu Wang Jiuwei Zhao Tim Li | 2022 | Atmospheric and Oceanic Science Letters2022，15，4： | 0 |
| 15 | Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells显示文摘瞄准:调查 TMPRSS2 的存在: 在从在监视肿瘤的前列腺癌症病人和它的潜力的传播肿瘤房间(CTC ) 的尔格熔化基因转移。方法:我们分析了 TMPRSS2 的频率:尔格和 TMPRSS2 : 在从前列腺切除术的 27 前列腺癌症活体检视的 ETV1 抄本,和 TMPRSS2 : 在与先进雄激素独立人士疾病使用从 15 个病人孤立的 CTC 的尔格抄本颠倒抄写聚合酶链反应(RT-PCR ) 。在 situ 杂交(鱼) 的荧光被使用分析尔格的 genomic 截断,它是 TMPRSS2 的结果: 在 15 件 CTC 样品中的 10 个的尔格熔化。结果: TMPRSS2:尔格抄本在 44% 我们的样品被发现,但是我们没检测 TMPRSS2 的表示: ETV1。用鱼分析,我们检测了在 10 件 CTC 样品中的 6 个影响 ERG 基因的 chromosomal 重新整理,包括有联系 TMPRSS2 的 1 个案例: 在主要地点的尔格熔化。然而, TMPRSS2 : 尔格抄本没在任何 15 件 CTC 样品被检测,包括 10 个盒子由鱼分析了。结论:尽管进一步的学习被要求探讨在 TMPRSS2 之间的协会: 尔格熔化和前列腺癌症转移,由鱼分析的 ERG 基因的 genomic 截断的察觉能为为前列腺癌症监视 CTC 和潜力的外观是有用的转移。 | Xueying Mao Greg Shaw Sharon Y. James Patricia Purkis Sakunthala C. Kudahetti Theodora Tsigani Saname Kia Bryan D. Young R. Tim D. Oliver Dan Berney David M. Prowse Yong-Jie Lu | 2008 | Asian Journal of Andrology2008，10，3： | 0 |
| 16 | Decreasing Trend of Western North Pacific Tropical Cyclone Inner-Core Size over the Past Decades显示文摘Studies on tropical cyclone(TC)inner-core size have become increasingly active in recent years.However,few studies have investigated the trend of TC inner-core size.Here,we introduce a new index to measure TC inner-core size and calculate the observed trend.This index can greatly reduce the influence of data heterogeneity and uncertainty.It also considers public concern because the new index is mainly determined by the inner-core size of strong TCs,which attract more public attention than weak TCs.The results show that in the past decades,TC inner-core size has a significant downtrend that is significant above the 99%confidence level when the new index is used.We also show that this trend is probably related to the increase in TC intensity and relatively small inner-core size of strong TCs.Moreover,relative sea surface temperature(SST)is assumed to make contributions to the downtrend of TC inner-core size,which has a significant negative correlation with the new index. | Hanrui SHOU Tim LI Yuan SUN Lu WANG Jia LIU | 2021 | Journal of Meteorological Research2021，35，4： | 0 |
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