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| 1 | Time course of expression of intermediate filament protein vimentin,nestin and desmin in rat renal glomerular injury显示文摘Podocytes in renal glomerulus express unusualintermediate filament proteins (IFs) for visceralepithelial cells. IFs cytoskeleton is mainly composed ofvimentin, nestin and desmin. Tissue injury is oftenaccompanied by changes in gene expression of IFs.Enhanced desmin staining in podocytes are observed in avariety of rat experimental models of podocyte injuryincluding puromycin aminonucleoside (PAN)nephrosis. It has not been elucidated whetherexpression of vimentin and nestin is up-regulated inpodocyte injury. To further gain insight into expression ofIFs in podocytes, we investigated the time course ofvimentin, nestin and desmin in PAN nephrosis. | ZOU Jun CHANG Tian-hui CHANG He Eishin Yaoita Yutaka Yoshida Masaaki Nameta Tadashi Yamamoto JIN Xin | 2007 | Chinese Medical Journal2007，，13： | 6 |
| 2 | Assessment of disease progression in patients with transfusion-associated chronic hepatitis C using transient elastography显示文摘AIM:To evaluate the relationship between liver stiffness and duration of infection in blood transfusion-associated hepatitis C virus (HCV) patients with or without hepatocellular carcinoma (HCC).METHODS:Between December 2006 and June 2008,a total of 524 transfusion-associated HCV-RNA positive patients with or without HCC were enrolled.Liver stiffness was obtained noninvasively by using Fibroscan (Echosens,Paris,France).The date of blood transfusion was obtained by interview.Duration of infection was derived from the interval between the date of bloodtransfusion and the date of liver stiffness measurement (LSM).Patients were stratified into four groups based on the duration of infection (17-29 years;30-39 years;40-49 years;and 50-70 years).The difference in liver stiffness between patients with and without HCC was assessed in each group.Multiple linear regression analysis was used to determine the factors associated with liver stiffness.RESULTS:A total of 524 patients underwent LSM.Eight patients were excluded because of unsuccessful measurements.Thus 516 patients were included in the current analysis (225 with HCC and 291 without).The patients were 244 men and 272 women,with a mean age of 67.8 ± 9.5 years.The median liver stiffness was 14.3 kPa (25.8 in HCC group and 7.6 in nonHCC group).The patients who developed HCC in short duration of infection were male dominant,having lower platelet count,with a history of heavier alcohol consumption,showing higher liver stiffness,and receiving blood transfusion at an old age.Liver stiffness was positively correlated with duration of infection in patients without HCC (r=0.132,P=0.024) but not in patients with HCC (r=-0.103,P=0.123).Liver stiffness was significantly higher in patients with HCC than in those without in each duration group (P < 0.0001).The factors significantly associated with high liver stiffness in multiple regression were age at blood transfusion (P < 0.0001),duration of infection (P=0.0015),and heavy alcohol consumption (P=0.043) CONCLUSION:Although liver stiffness gradually increases over time,HCC develops in patients with high stiffness value regardless of the duration of infection. | Ryota Masuzaki Ryosuke Tateishi Haruhiko Yoshida Toru Arano Koji Uchino Kenichiro Enooku Eriko Goto Hayato Nakagawa Yoshinari Asaoka Yuji Kondo Tadashi Goto Hitoshi Ikeda Shuichiro Shiina Masao Omata Kazuhiko Koike | 2012 | World Journal of Gastroenterology2012，18，12： | 4 |
| 3 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida Fumitake Toki Tadashi Takeuchi Shin-Ichiro Watanabe Keiko Shiratori Naoaki Hayashi | 1995 | Digestive Diseases and Sciences1995，，7： | 4 |
| 4 | Safety and efficacy of lamivudine after radiofrequency ablation in patients with hepatitis B virus-related hepatocellular carcinoma显示文摘 | Hideo Yoshida Haruhiko Yoshida Eriko Goto Takahisa Sato Takamasa Ohki Ryota Masuzaki Ryosuke Tateishi Tadashi Goto Shuichiro Shiina Takao Kawabe Masao Omata | 2008 | Hepatology International2008，，1： | 3 |
| 5 | Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection显示文摘 | Yue Wang Naoya Kato Yujin Hoshida Hideo Yoshida Hiroyoshi Taniguchi Tadashi Goto Masaru Moriyama Motoyuki Otsuka Shuichiro Shiina Yasushi Shiratori Yoichi Ito Masao Omata | 2003 | Hepatology2003，，： | 3 |
| 6 | Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy显示文摘 | Hiroto Izumi Takayuki Torigoe Hiroshi Ishiguchi Hidetaka Uramoto Yoichiro Yoshida Mizuho Tanabe Tomoko Ise Tadashi Murakami Takeshi Yoshida Minoru Nomoto Kimitoshi Kohno | 2003 | Cancer Treatment Reviews2003，，6： | 2 |
| 7 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida MD Fumitake Toki MD Tadashi Takeuchi MD Shin-Ichiro Watanabe MD Keiko Shiratori MD Naoaki Hayashi MD | 1995 | Digestive Diseases and Sciences1995，，7： | 2 |
| 8 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida MD Fumitake Toki MD Tadashi Takeuchi MD Shin-Ichiro Watanabe MD Keiko Shiratori MD Naoaki Hayashi MD | 1995 | Digestive Diseases and Sciences1995，，7： | 2 |
| 9 | Laparoscopic splenectomy for histiocytic sarcoma of the spleen显示文摘Primary histiocytic sarcoma of the spleen is a rare but potentially lethal condition. It can remain asymptomatic or only mildly symptomatic for a long time. An 81-year-old woman presented with an extremely enlarged spleen. She suffered from progressive anemia and required a red blood cell transfusion once a month. Although computed tomography, ultrasonography, and magnetic resonance imaging were performed for diagnosis, a confirmed diagnosis was not obtained. Her enlarged spleen compressed her stomach, and she suffered from gastritis and a sense of gastric fullness just after meals. She underwent laparoscopic splenectomy for therapeutic and diagnostic purposes. Her postoperative course was uneventful. After surgery, her red blood cell and platelet counts increased markedly. The tumor was diagnosed as splenic histiocytic sarcoma. Post-surgical chemotherapy was not performed, and the patient died of liver failure due to liver metastasis 5 mo after surgery. Laparoscopic splenectomy is minimally invasive and useful for the relief of symptoms related to hematological disorders. However, in cases of an enlarged spleen, optimal views and working space are limited. In such cases, splenic artery ligation can markedly reduce the size of the spleen, thus facilitating the procedure. The case reported herein suggests that laparoscopic splenectomy may be useful for the treatment of splenic malignancy. | Satoshi Yamamoto Tadashi Tsukamoto Akishige Kanazawa Sadatoshi Shimizu Keiichiro Morimura Takahiro Toyokawa Zhang Xiang Katsunobu Sakurai Tatsunari Fukuoka Kayo Yoshida Mamiko Takii Ken Inoue | 2013 | World Journal of Gastrointestinal Surgery2013，5，4： | 2 |
| 10 | Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography显示文摘 | Ryota Masuzaki Ryosuke Tateishi Haruhiko Yoshida Eriko Goto Takahisa Sato Takamasa Ohki Jun Imamura Tadashi Goto Fumihiko Kanai Naoya Kato Hitoshi Ikeda Shuichiro Shiina Takao Kawabe Masao Omata | 2009 | Hepatology2009，，： | 2 |
| 11 | β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo显示文摘 | David R. Murray Srinivas Mummidi Anthony J. Valente Tadashi Yoshida Naveen K. Somanna Patrice Delafontaine Charles A. Dinarello Bysani Chandrasekar | 2011 | Journal of Molecular and Cellular Cardiology2011，，1： | 2 |
| 12 | Treatment strategy for hepatocellular carcinoma: expanding the indications for radiofrequency ablation显示文摘 | Ryosuke Tateishi Shuichiro Shiina Takamasa Ohki Takahisa Sato Ryota Masuzaki Jun Imamura Eriko Goto Tadashi Goto Hideo Yoshida Shuntaro Obi Shinpei Sato Fumihiko Kanai Haruhiko Yoshida Masao Omata | 2009 | Journal of Gastroenterology2009，，19： | 1 |
| 13 | Chronic pancreatitis caused by an autoimmune abnormality显示文摘 | Kenji Yoshida MD Fumitake Toki MD Tadashi Takeuchi MD Shin-Ichiro Watanabe MD Keiko Shiratori MD Naoaki Hayashi MD | 1995 | Digestive Diseases and Sciences1995，，7： | 1 |
| 14 | 3-D Finite Element Analysis of a Linear Induction Motor 显示文摘 | Tadashi Yamaguchi Yoshihiro Kawase Makoto Yoshida | 2001 | IEEE Transactions on Magnetics2001，37，5： | 1 |
| 15 | Effects of bile salts on cholestan-3 6,5 α, 613-triol-induced apopto- sis in dog gallbladder epithelial cells显示文摘 | Tadashi Yoshida J Henriette Klinkspoor Rahul Kuver | 2001 | Biochimica et Biophys- ica Acta2001，1530，23： | 1 |
| 16 | Safety and efficacy of lamivudine after radiofrequency ablation in patients with hepatitis B virus-related hepatocellular carcinoma显示文摘 | Hideo Yoshida Haruhiko Yoshida Eriko Goto Takahisa Sato Takamasa Ohki Ryota Masuzaki Ryosuke Tateishi Tadashi Goto Shuichiro Shiina Takao Kawabe Masao Omata | 2008 | Hepatology International2008，，1： | 1 |
| 17 | Balance between genetic search and local search in mimetic algorithms for multi-objective permutation flow-shop scheduling显示文摘 | Hisao Ishibuchi Tadashi Yoshida Tadahiko Murata | 2003 | IEEE Transactions on Evolutionary Computation2003，7，2： | 1 |
| 18 | MicroRNA‐140 acts as a liver tumor suppressor by controlling NF‐κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression显示文摘 | Akemi Takata Motoyuki Otsuka Takeshi Yoshikawa Takahiro Kishikawa Yohko Hikiba Shuntaro Obi Tadashi Goto Young Jun Kang Shin Maeda Haruhiko Yoshida Masao Omata Hiroshi Asahara Kazuhiko Koike | 2013 | Hepatology2013，，1： | 1 |
| 19 | Characterisation of proanthocyanidins from black soybeans: Isolation and characterisation of proanthocyanidin oligomers from black soybean seed coats显示文摘 | Chiaki Ito Tomoyuki Oki Tadashi Yoshida Fumio Nanba Katsushige Yamada Toshiya Toda | 2013 | Food Chemistry2013，，3： | 1 |
| 20 | Nano-scale simultaneous observation of Li-concentration profile and Ti-, O electronic structure changes in an all-solid-state Li-ion battery by spatially-resolved electron energy-loss spectroscopy显示文摘 | Kazuo Yamamoto Ryuji Yoshida Takeshi Sato Hiroaki Matsumoto Hisanori Kurobe Tadashi Hamanaka Takehisa Kato Yasutoshi Iriyama Tsukasa Hirayama | 2014 | Journal of Power Sources2014，，： | 1 |
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