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| 1 | Percutaneous endoscopic gastrostomy under steadypressure automatically controlled endoscopy:First clinicalseries显示文摘AIM: To elucidate the safety of percutaneous endoscopic gastrostomy(PEG) under steady pressure automatically controlled endoscopy(SPACE) using carbon dioxide(CO_2).METHODS: Nine patients underwent PEG with a modified introducer method under conscious sedation. A T-tube was attached to the channel of an endoscope connected to an automatic surgical insufflator. The stomach was inflated under the SPACE system. The intragastric pressure was kept between 4-8 mmH g with a flow of CO_2 at 35 L/min. Median procedure time, intragastric pressure, median systolic blood pressure, partial pressure of CO_2, abdominal girth before and immediately after PEG, and free gas and small intestinal gas on abdominal X-ray before and after PEG were recorded. RESULTS: PEG was completed under stable pneumostomach in all patients, with a median procedural time of 22 min. Median intragastric pressure was 6.9 mmH g and median arterial CO_2 pressure before and after PEG was 42.1 and 45.5 Torr(NS). The median abdominal girth before and after PEG was 68.1 and 69.6 cm(NS). A mild free gas image after PEG was observed in two patients, and faint abdominal gas in the downstream bowel was documented in two patients.CONCLUSION: SPACE might enable standardized pneumostomach and modified introducer procedure of PEG. | Hiroyuki Imaeda Kiyokazu Nakajima Naoki Hosoe Masanori Nakahara Shinichiro Zushi Motohiko Kato Kazuhiro Kashiwagi Yasushi Matsumoto Kayoko Kimura Rieko Nakamura Norihito Wada Masahiko Tsujii Naohisa Yahagi Toshifumi Hibi Takanori Kanai Tetsuo Takehara Haruhiko Ogata | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，3： | 2 |
| 2 | Signaling cascades in radiation-induced apoptosis:Roles of protein kinase C in the apoptosis regulation显示文摘 | Tetsuo Nakajima | 2006 | Med Sci Monit2006，12，10： | 1 |
| 3 | Significant elevation of serum interleukin-18 levels in patients with acute pancreatitis显示文摘 | Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Hidehiro Sawa Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，2： | 1 |
| 4 | A novel endoscopic submucosal dissection technique with robust and adjustable tissue traction显示文摘 | Masashi Hirota Motohiko Kato Makoto Yamasaki Naoki Kawai Yasuhiro Miyazaki Takuya Yamada Tsuyoshi Takahashi Tetsuo Takehara Masaki Mori Yuichiro Doki Kiyokazu Nakajima | 2014 | Endoscopy2014，，： | 1 |
| 5 | Apoptosis of T cells in the hepatic fibrotic tissue of the rat: a possible inducing role of hepatic myofibroblast-like cells显示文摘 | Sawako Kobayashi Shuichi Seki Norifumi Kawada Hiroyasu Morikawa Kazuki Nakatani Naoki Uyama Kazuo Ikeda Yuji Nakajima Tetsuo Arakawa Kenji Kaneda | 2003 | Cell and Tissue Research2003，，3： | 1 |
| 6 | Prediction of early death in severe acute pancreatitis显示文摘 | Makoto Shinzeki Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Hidehiro Sawa Takahiro Nakajima Ippei Matsumoto Tsunenori Fujita Tetsuo Ajiki Yasuhiro Fujino Yoshikazu Kuroda | 2008 | Journal of Gastroenterology2008，，： | 1 |
| 7 | Elevation of plasma tissue factor levels in patients with severe acute pancreatitis显示文摘 | Hidehiro Sawa Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，6： | 1 |
| 8 | Immunosuppression in patients with severe acute pancreatitis显示文摘 | Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，8： | 1 |
| 9 | A murine model of granulomatous colitis with mesenteric lymphadenitis induced by mycobacterial cord factor显示文摘 | Mitsue Sogawa Takayuki Matsumoto Hirokazu Yamagami Tamaki Yamada Yuriko Ozeki Ikuya Yano Yuji Nakajima Tetsuo Arakawa Kenji Kaneda | 2003 | Virchows Archiv2003，，2： | 1 |
| 10 | Standardization of the heart-to-mediastinum ratio of 123I-labelled-metaiodobenzylguanidine uptake using the dual energy window method: feasibility of correction with different camera–collimator combinations显示文摘 | Shinro Matsuo Kenichi Nakajima Koichi Okuda Masaya Kawano Takehiro Ishikawa Tetsuo Hosoya Junichi Taki Seigo Kinuya | 2009 | European Journal of Nuclear Medicine and Molecular Imaging2009，，4： | 1 |
| 11 | Treatment strategy against infection: clinical outcome of continuous regional arterial infusion, enteral nutrition, and surgery in severe acute pancreatitis显示文摘 | Takeo Yasuda Takashi Ueda Yoshifumi Takeyama Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Ippei Matsumoto Tsunenori Fujita Tetsuya Sakai Tetsuo Ajiki Yasuhiro Fujino Yoshikazu Kuroda | 2007 | Journal of Gastroenterology2007，，8： | 1 |
| 12 | Elevation of plasma tissue factor levels in patients with severe acute pancreatitis显示文摘 | Hidehiro Sawa Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，6： | 1 |
| 13 | Spontaneous Resolution of Chronic Subdural Hematomas显示文摘 | Hirofumi Naganuma Akira Fukamachi Motomasa Kawakami Shuzoh Misumi Hideo Nakajima Tetsuo Wakao | 1986 | Neurosurgery1986，，5： | 1 |
| 14 | Significant elevation of serum interleukin-18 levels in patients with acute pancreatitis显示文摘 | Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Hidehiro Sawa Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，2： | 1 |
| 15 | Treatment strategy against infection: clinical outcome of continuous regional arterial infusion, enteral nutrition, and surgery in severe acute pancreatitis显示文摘 | Takeo Yasuda Takashi Ueda Yoshifumi Takeyama Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Ippei Matsumoto Tsunenori Fujita Tetsuya Sakai Tetsuo Ajiki Yasuhiro Fujino Yoshikazu Kuroda | 2007 | Journal of Gastroenterology2007，，8： | 1 |
| 16 | Immunosuppression in patients with severe acute pancreatitis显示文摘 | Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda | 2006 | Journal of Gastroenterology2006，，8： | 1 |
| 17 | More efficient induction of genotoxicity by high-LET Fe-particle radiation than low-LET X-ray radiation at low doses显示文摘Objective:To understand differential effects on induction of genotoxicity and genomic instability(GI)by high-LET particle radiation and low-LET photon radiation,based on ground-based experiments using total body irradiation(TBI)of mice with Fe-particle radiation and X-ray radiation.Methods:TBI was delivered to C57BL/6J Jms strain female mice of 8 weeks old at a dose ranging from 0.1 to 3.0 Gy of Fe-particle radiation or at a dose ranging from 0.1 to 5.0 Gy of X-ray radiation.Induction of genotoxicity and GI by TBI was determined respectively at 1 and 2 months after exposure using frequency of micronuclei in bone marrow erythrocytes as the endpoint.Inhibition of bone marrow cell proliferation by TBI was measured as reduced erythropoiesis.Physiological conditions were also investigated.Results:TBI,regardless of the type of radiation,caused statistically significant increase in genotoxicity at 1 month after exposure,but did not induce GI at 2 months after exposure even at higher doses(>1.0 Gy).The doseresponse curve for the frequency of micronucleated polychromatic erythrocytes induced by Fe-particle radiation and X-ray radiation was y=0.7798 t 1.7889x–0.5978x^(2)(R^(2)=0.8109)and y=0.7421 t 1.3792x–0.2588 x^(2)(R^(2)=0.8081),respectively.The dose-response curve for the frequency of micronucleated normochromatic erythrocytes induced by Fe-particle radiation and X-ray radiation was y=0.7191 t 1.4545x–0.4978x^(2)(R^(2)=0.7047)and y=0.658 t 1.344x–0.2531x^(2)(R^(2)=0.7853),respectively.In general,high-LET Fe-particle radiation was more efficient in inducing genotoxicity than low-LET X-ray radiation at lower doses(<0.5 Gy).Conclusions:These results further confirm that exposure to TBI,even at higher doses and regardless the type of radiation,does not induce GI in C57BL/6J strain mice measured as increased micronuclei in bone marrow erythrocytes.These findings indicate that radiation-induced GI is mouse strain dependent and suggest that more comprehensive studies should be done to explore the late health consequences from exposure to high-LET radiation at low doses. | Bing Wang Takanori Katsube Kaoru Tanaka Yasuharu Ninomiya Hirokazu Hirakawa Cuihua Liu Kouichi Maruyama Masahiro Murakami Tetsuo Nakajima Akira Fujimori Mitsuru Nenoi | 2023 | Radiation Medicine and Protection2023，4，1： | 0 |
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