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1基于线粒体基因对细痣疣螈种组系统发育关系的探讨及物种修订建议(英文)显示文摘该文基于两段线粒体基因COI和ND1-ND2部分序列片段构建了细痣疣螈种组的系统发育关系,结果显示该单系群内包含了四个明显的进化支系(A、B、C、D)。A支系与B、C支系构成姐妹群关系;A支系包含了细痣疣螈、海南疣螈、老挝疣螈和'越南疣螈'以及另外两个来自越南未被命名的种群;C支系代表了一个新的独立进化支,可能是一个隐存种;C支系与B支系构成姐妹群关系。此外,来自模式产地的越南疣螈单独构成支系D。该文结果不支持以往细痣疣螈种组部分物种的划分,建议对该种组进行新的分类修订。该文强调了在分类研究中应该重视使用来自模式产地的样品并进行广泛的地理居群采样。袁智勇 蒋柯 吕顺清 杨军校 NGUYEN Quang Truong NGUYEN Thien Tao 金洁琼 车静 2011Zoological Research2011,32,6:8
2Xanthine oxidase inhibitors from Archidendron clypearia(Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants显示文摘Objective: To screen Vietnamese medicinal plants for xanthine oxidase(XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. Methods: The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ethyl acetate, and n-butanol. Bioassay-guided fractionation and column chromatography were used to isolate compounds. The compounds structures were elucidated by analysis of spectroscopic data, including IR, MS, and NMR. Results: Three hundreds and eleven methanol extracts(CME) belonging to 301 Vietnamese herbs were screened for XO inhibitory activity. Among these plants, 57 extracts displayed XO inhibitory activity at 100 μg/m L with inhibition rates of over 50%. The extracts of Archidendron clypearia, Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC_(50) values below 30 μg/m L. Chemical study performed on the extract of Archidendron clypearia resulted in the isolation of six compounds, including 1-octacosanol, docosenoic acid, daucosterol, methyl gallate, quercitrin and(-)-7-O-galloyltricetiflavan. The compound(-)-7-O-galloyltricetiflavan showed the most potent XO inhibitory activity with an IC_(50) value of 25.5 μmol/L. Conclusions: From this investigation, four Vietnamese medicinal plants were identified to have XO inhibitory effects with IC_(50) values of the methanol extracts below 30 μg/m L. Compound(-)-7-O-galloyltricetiflavan was identified as an XO inhibitor from Archidendron clypearia with IC_(50) value of 25.5 μmol/L.Nguyen Thuy Duong Pham Duc Vinh Phuong Thien Thuong Nguyen Thi Hoai Le Nguyen Thanh Tran The Bach Nguyen Hai Nam Nguyen Hoang Anh 2017Asian Pacific Journal of Tropical Medicine2017,10,6:5
3COVID-19 vaccination intention among healthcare workers in Vietnam显示文摘Objective:To assess the acceptance of coronavirus disease(COVID-19)vaccine among healthcare workers at two general hospitals in Vietnam when it is available.Methods:A cross-sectional study was conducted using a convenience sampling from January to February 2021 among 410 healthcare workers at two general hospitals in Vietnam via a selfadministered questionnaire.A multivariable regression analysis was performed to determine predictors of vaccine acceptance including the demographic factors,COVID-19 knowledge,and vaccine beliefs based on the domains of Health Belief Model.Results:Among 410 healthcare workers,76.10%showed vaccination willingness.Predictors of acceptance were determined that the group reporting as“vaccine acceptance”was more likely to be positive towards the perceived susceptibility and severity of COVID-19(OR 2.45;95%CI 1.48-4.06,P<0.05),perceived benefits of vaccination,and cues to action(OR 4.36;95%CI 2.35-8.09,and OR 5.49;95%CI 2.84-10.61,respectively,all P<0.001),but less likely to have the perceived barriers to vaccination(OR 0.19;95%CI 0.09-0.38;P<0.001)compared with the no acceptance group.Besides,people who had a good knowledge regarding the severity of illness were 3.37 times more likely to have identified as vaccine acceptance(OR 3.37;95%CI 1.04-10.86,P<0.05).The demographic factors were also associated with willingness to receive the vaccine,with participants who were staff and received COVID-19 information from relatives were less likely to accept the vaccine over those who were doctors and not receiving information from relatives(OR 0.36;95%CI 0.13-0.96,and OR 0.37;95%CI 0.17-0.78,respectively,all P<0.05).Conclusions:A rate of willingness to get vaccinated against COVID-19 was relatively high with discrepancies between occupation,receiving information from relatives,knowledge toward the severity of illness,and the elements of Health Belief Model.The findings will provide information for the management authorities to develop relevant interventions to promote COVID-19 vaccination uptake.Giao Huynh Thien Thuan Tran Han Thi Ngoc Nguyen Le An Pham 2021Asian Pacific Journal of Tropical Medicine2021,14,4:3
4On the Generic Taxonomy of Opisthotropis balteata(Cope, 1895)(Squamata: Colubridae: Natricinae): Taxonomic Revision of Two Natricine Genera显示文摘The single prefrontal configuration has historically been used as an important diagnostic character for many natricine taxa. For example, the genus Trimerodytes Cope, 1895 was long been regarded as a junior synonym of Opisthotropis Günther, 1872 for their similar prefrontal configurations and the type species, T. balteatus Cope, 1895, has been assigned to the genus Opisthotropis. However, as the number and arrangement of prefrontal vary frequently both at species and generic level, it is questionable whether the synonymization of Trimerodytes reflects their evolutionary relationships. On the basis of recently collected specimens of O. balteata, the generic status of the species was assessed using both molecular and morphological data. Opisthotropis was recovered as polyphyletic with reference to O. balteata, because O. balteata is nested within the genus Sinonatrix Rossman and Eberle, 1977 and is the sister species of the type species of Sinonatrix. Consequently, we herein resurrect the long-overlooked synonym Trimerodytes from Opisthotropis and synonymize the junior generic nomen Sinonatrix with Trimerodytes. In addition, based on morphological similarities between the monotypic genus Paratapinophis Angel, 1929 and Trimerodytes, we doubt about the validity of Paratapinophis. Following taxonomic changes in this work, the taxonomic account of the genus Trimerodytes, updated descriptions of its type species, and diagnostic key to Trimerodytes species are provided.Jinlong REN Kai WANG Peng GUO Yingyong WANG Tao Thien NGUYEN Jiatang LI 2019Asian Herpetological Research2019,10,2:3
5A New Species of Rhacophorus(Amphibia:Anura:Rhacophoridae)from Vietnam显示文摘We describe a new species of Rhacophorus based on two adult specimens collected from Hoa Binh Province, northern Vietnam. Rhacophorus hoabinhensis sp. nov. is distinguishable from its congeners on the basis of a combination of the following morphological characters: size small(SVL 31.1–32.5 mm in males); head slightly longer than wide; vomerine teeth absent; snout short(SNL/SVL 0.16); dorsal skin smooth; forearm and tarsus with dermal fringes; dermal appendage at vent present; webbing formula on fingers Ⅰ12/3-12/3 Ⅱ1-2 Ⅲ1-1 Ⅳ and on toes Ⅰ3/4-1 Ⅱ1/2-1Ⅲ1/2-1 Ⅳ1-1/2Ⅳ; dorsal surface grey yellow with brown spots; lower jaw region dark grey, throat, chest and belly cream; anterior and posterior thighs, as well as ventral surface of tibia orange. The interspecific uncorrected genetic distances(16 S rRNA gene) between the new species from Hoa Binh and other analyzed congeners varied from 9.8% to 17.4%. In the phylogenetic analyses, the new species revealed to be a representative of Rhacophorus and was nested within the R. hoanglienensis-orlovi species group.Tao Thien NGUYEN Cuong The PHAM Truong Quang NGUYEN Hoa Thi NINH Thomas ZIEGLER 2017Asian Herpetological Research2017,18,4:2
6Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy显示文摘Tianhong Xu Zhao Yang Matteo Vatta Alessandra Rampazzo Giorgia Beffagna Kalliopi Pillichou Steven E. Scherer Jeffrey Saffitz Joshua Kravitz Wojciech Zareba Gian Antonio Danieli Alessandra Lorenzon Andrea Nava Barbara Bauce Gaetano Thiene Cristina Basso Hu 2010Journal of the American College of Cardiology2010,,6:2
7Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβplaques and brain rhythms in 5×FAD mice显示文摘Background:Alzheimer's disease(AD)is the most common cause of dementia,and is characterized by amyloid-β(Aβ)plaques and tauopathy.Reducing Aβhas been considered a major AD treatment strategy in pharmacological and non-pharmacological approaches.Impairment of gamma oscillations,which play an important role in perception and cognitive function,has been shown in mouse AD models and human patients.Recently,the therapeutic effect of gamma entrainment in AD mouse models has been reported.Given that ultrasound is an emerging neuromodulation modality,we investigated the effect of ultrasound stimulation pulsed at gamma frequency(40 Hz)in an AD mouse model.Methods:We implanted electroencephalogram(EEG)electrodes and a piezo-ceramic disc ultrasound transducer on the skull surface of 6-month-old 5×FAD and wild-type control mice(n=12 and 6,respectively).Six 5×FAD mice were treated with two-hour ultrasound stimulation at 40 Hz daily for two weeks,and the other six mice received sham treatment.Soluble and insoluble Aβlevels in the brain were measured by enzyme-linked immunosorbent assay.Spontaneous EEG gamma power was computed by wavelet analysis,and the brain connectivity was examined with phase-locking value and cross-frequency phase-amplitude coupling.Results:We found that the total Aβ42 levels,especially insoluble Aβ42;in the treatment group decreased in pre-and infra-limbic cortex(PIL)compared to that of the sham treatment group.A reduction in the number of Aβplaques was also observed in the hippocampus.There was no increase in microbleeding in the transcranial ultrasound stimulation(tUS)group.In addition,the length and number of microglial processes decreased in PIL and hippocampus.Encel-phalographic spontaneous gamma power was increased,and cross-frequency coupling was normalized,implying functional improvement after tUS stimulation.Conclusion:These results suggest that the transcranial ultrasound-based gamma-band entrainment technique can be an effective therapy for AD by reducing the Aβload and improving brain connectivity.Mincheol Park Gia Minh Hoang Thien Nguyen Eunkyung Lee Hyun Jin Jung Youngshik Choe Moon Hwan Lee Jae Youn Hwang Jae Gwan Kim Tae Kim 2021Translational Neurodegeneration2021,10,4:2
8Effect of Cyclosporine on Left Ventricular Remodeling After Reperfused Myocardial Infarction显示文摘Nathan Mewton Pierre Croisille Gerald Gahide Gilles Rioufol Eric Bonnefoy Ingrid Sanchez Thien Tri Cung Catherine Sportouch Denis Angoulvant Gérard Finet Xavier André-Fou?t Geneviève Derumeaux Christophe Piot Hélène Vernhet Didier Revel Michel Ovize 2010Journal of the American College of Cardiology2010,,12:2
9Frequency of Bicuspid Aortic Valve in Young Male Conscripts by Echocardiogram显示文摘Stefano Nistri Cristina Basso Chiara Marzari Paolo Mormino Gaetano Thiene 2005The American Journal of Cardiology2005,,5:2
10Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies显示文摘P. : Richardson W. Rapporteur: McKenna M. Committee: Bristow B. Maisch B. Mautner J. O'Connell E. Olsen G. Thiene J. Consultant: Goodwin I. WHO Staff: Gyarfas I. Martin P. Nordet 1996Circulation1996,,5:2
11Hypertrophic cardiomyopathy and sudden death in the young: Pathologic evidence of myocardial ischemia显示文摘Cristina Basso Gaetano Thiene Domenico Corrado Gianfranco Buja Paola Melacini Andrea Nava 2000Human Pathology2000,,8:2
12Microbial responses to combined oxidation and catalysis treatment of 1,4-dioxane and co-contaminants in groundwater and soil显示文摘Post-treatment impacts of a novel combined hydrogen peroxide(H2O_(2))oxidation and WOx/ZrO_(2) catalysis used for the removal of 1,4-dioxane and chlorinated volatile organic compound(CVOC)contaminants were investigated in soil and groundwater microbial community.This treatment train removed~90%1,4-dioxane regardless of initial concentrations of 1,4-dioxane and CVOCs.The Illumina Miseq platform and bioinformatics were used to study the changes to microbial community structure.This approach determined that dynamic shifts of microbiomes were associated with conditions specific to treatments as well as 1,4-dioxane and CVOCs mixtures.The biodiversity was observed to decrease only after oxidation under conditions that included high levels of 1,4-dioxane and CVOCs,but increased when 1,4-dioxane was present without CVOCs.WO_(x)/ZrO_(2) catalysis reduced biodiversity across all conditions.Taxonomic classification demonstrated oxidative tolerance for members of the genera Massilia and Rhodococcus,while catalyst tolerance was observed for members of the genera Sphingomonas and Devosia.Linear discriminant analysis effect size was a useful statistical tool to highlight representative microbes,while the multidimensional analysis elucidated the separation of microbiomes under the low 1,4-dioxane-only condition from all other conditions containing CVOCs,as well as the differences of microbial population among original,post-oxidation,and post-catalysis states.The results of this study enhance our understanding of microbial community responses to a promising chemical treatment train,and the metagenomic analysis will help practitioners predict the microbial community status during the post-treatment period,which may have consequences for long-term management strategies that include additional biodegradation treatment or natural attenuation.Yu Miao Nicholas W.Johnson Kimberly Heck Sujin Guo Camilah D.Powell Thien Phan Phillip B.Gedalanga David T.Adamson Charles J.Newell Michael S.Wong Shaily Mahendra 2018Frontiers of Environmental Science & Engineering2018,12,5:2
13Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies显示文摘P. : Richardson W. Rapporteur: McKenna M. Committee: Bristow B. Maisch B. Mautner J. O’Connell E. Olsen G. Thiene J. Consultant: Goodwin I. WHO Staff: Gyarfas I. Martin P. Nordet 1996Circulation1996,,5:2
14Dispersion of Ventricular Depolarization-Repolarization: A Noninvasive Marker for Risk Stratification in Arrhythmogenic Right Ventricular Cardiomyopathy显示文摘Pietro Turrini Domenico Corrado Cristina Basso Andrea Nava Barbara Bauce Gaetano Thiene 2001Circulation: Journal of the American Heart Association2001,,:2
15Reoperations for acute prosthetic thrombosis and pannus: an assessment of rates, relationship and risk显示文摘G. Rizzoli C. Guglielmi G. Toscano V. Pistorio I. Vendramin T. Bottio G. Thiene D. Casarotto 1999European Journal of Cardio-Thoracic Surgery1999,,1:2
16Antioxidant activity and principles of Vietnam bitter tea Ilex kudingcha显示文摘Phuong Thien Thuong Nguyen Duy Su Tran Minh Ngoc Tran Manh Hung Nguyen Hai Dang Nguyen Duy Thuan KiHwan Bae Won Keun Oh 2008Food Chemistry2008,,1:2
17Baculovirus Host-Range显示文摘Baculoviruses are used as microbial insecticides, protein expression vectors, epitope display platforms, and most recently as vectors for gene therapy. Understanding the mechanisms that control baculovirus host-range and tissue tropisms are important for assessing their safety and for improving their properties for these biotechnology applications. In the past two decades some progress has been made and several baculovirus genes that influence host-range have been identified. Despite this progress, our understanding of the underlying mechanisms that restrict baculovirus host-range is still limited. Here we review what is currently known about baculovirus genes that influence virus host-range.Suzanne M. Thien Xiao-Wen Cheng 2009Virologica Sinica2009,24,5:2
18Anomalous origin of coronary arteries and risk of sudden death: A study based on an autopsy population of congenital heart disease显示文摘Carla Frescura Cristina Basso Gaetano Thiene Domenico Corrado Tommaso Pennelli Annalisa Angelini Luciano Daliento 1998Human Pathology1998,,:2
19Endothelin A-receptor antagonist administration immediately after ex- perimental myocardial infarction with reperfusion does not affect scar healing in dogs 显示文摘Basso C Thiene G Della-Barbera M 2002Cardiovas Res2002,55,1:1
20Congenital coronary artery anomalies as an important cause of sudden death in the young 显示文摘Basso C Corrado D Thiene G 2001Cardiol Rev2001,9,:1
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