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| 1 | Anterior Approach Versus Conventional Approach Right Hepatic Resection for Large Hepatocellular Carcinoma: A Prospective Randomized Controlled Study显示文摘 | Chi Leung Liu Sheung Tat Fan Siu Tim Cheung Chung Mau Lo Irene O. Ng John Wong | 2006 | Annals of Surgery2006，，2： | 2 |
| 2 | Claudin -10 ex- pression level is associated with recurrence of primary hepatocellular carci- noma 显示文摘 | Siu Tim Cheung Ka Ling Leung Ying Chi Ip | 2005 | Clin Cancer Res2005，11，21： | 1 |
| 3 | Inhibition of hepa- toeellular carcinoma invasion by suppression of claudin - 10 in HLE cells 显示文摘 | Ying Chi Ip Siu Tim Cheung Yuk Ting Lee | 2007 | Mol Cancer Ther2007，6，11： | 1 |
| 4 | Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma显示文摘 | Tian Yuan Wong Vincent W.S. Wong Grace L.H. Yang Weiqin Sun Hanyong Shen Jiayun Tong Joanna H.M. Go Minnie Y.Y. Cheung Yue S. Lai Paul B.S. Zhou Mingyan Xu Gang Huang Tim H.M. Yu Jun To Ka F. Cheng Alfred S.L. Chan Henry L.Y | 2015 | Cancer Research2015，，22： | 1 |
| 5 | Back to the Future显示文摘 | Wing-Yee Cheung Tim Wildschut Constantine Sedikides Erica G. Hepper Jamie Arndt Ad J. J. M. Vingerhoets | 2013 | Personality and Social Psychology Bulletin2013，，： | 1 |
| 6 | Clinical significance of thrombospondin 1 expression in hepatocellular carcinoma 显示文摘 | Poon RT Ka Kit Chung Siu Tim Cheung | 2004 | Clin Cancer Res2004，10，： | 1 |
| 7 | Anterior Approach Versus Conventional Approach Right Hepatic Resection for Large Hepatocellular Carcinoma: A Prospective Randomized Controlled Study显示文摘 | Chi Leung Liu Sheung Tat Fan Siu Tim Cheung Chung Mau Lo Irene O. Ng John Wong | 2006 | Annals of Surgery2006，，2： | 1 |
| 8 | Novel biomarkers GEP/ABCB5 regulate response to adjuvant transarterial chemoembolization after curative hepatectomy for hepatocellular carcinoma显示文摘Background: Transarterial chemoembolization(TACE) is the most commonly used adjuvant therapy for hepatocellular carcinoma(HCC) after curative resection. Responses to TACE are variable due to tumor and patient heterogeneity. We had previously demonstrated that expression of Granulin-epithelin precursor(GEP) and ATP-dependent binding cassette(ABC)B5 in liver cancer stem cells was associated with chemoresistance. The present study aimed to evaluate the association between GEP/ABCB5 expression and response to adjuvant TACE after curative resection for HCC. Methods: Patients received adjuvant TACE after curative resection for HCC and patients received curative resection alone were identified from a prospectively collected database. Clinical samples were retrieved for biomarker analysis. Patients were categorized into 3 risk groups according to their GEP/ABCB5 status for survival analysis: low(GEP-/ABCB5-), intermediate(either GEP +/ABCB5-or GEP-/ABCB5 +) and high(GEP +/ABCB5 +). Early recurrence(recurrence within 2 years after resection) and disease-free survival were analyzed. Results: Clinical samples from 44 patients who had followed-up for more than 2 years were retrieved for further biomarker analysis. Among them, 18 received adjuvant TACE and 26 received surgery alone. Patients with adjuvant TACE in the intermediate risk group was associated with significantly better overall survival and 2-year disease-free survival than those who had surgery alone( P = 0.036 and P = 0.011, respectively). Adjuvant TACE did not offer any significant differences in the early recurrence rate, 2-year disease-free survival and overall survival for patients in low and high risk groups. Conclusions: Adjuvant TACE can only provide survival benefits for patients in the intermediate risk group(either GEP +/ABCB5-or GEP-/ABCB5 +). A larger clinical study is warranted to confirm its role in patient selection for adjuvant TACE. | Charing Ching-Ning Chong Siu Tim Cheung Yue-Sun Cheung Anthony Wing-Hung Chan Stephen Lam Chan Simon Chun-Ho Yu Paul Bo-San Lai | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 0 |
| 9 | “跃动达令港”:悉尼国际会展娱乐综合区(SICEEP)显示文摘全球各地对于"世界级"建筑的热切需求衍生出许多大同小异的综合体。虽然这些综合体能积极充当各种活动的"场地",但它们却未能回应所在地方的个别情况和环境。OMA与发展联合体为"悉尼国际会展娱乐综合区"进行总体规划工作时,摒弃了用于一般"世界级"建筑的设计手法,取而代之的是集会议、娱乐、展览、文化和商业设施于一体的综合配置,这些设施将创造最有利的条件, | Viviano Villamal Buerón Kathlecn Cayelano Tim Cheung Kanlina Czeczek Baniel Hui Charles Lai Cristina Martinde Juan Rieky Suem Ka Tam Hannah Zhang Andreas Viglakis | 2014 | 城市环境设计2014，，6： | 0 |
| 10 | Virtual reality based multiple life skill training for intellectual disability:A multicenter randomized controlled trial显示文摘Life skill-based training is essential for intellectual disabled individuals to regain autonomy and social inclusion.Virtual reality(VR)could deliver a nascent application that is more engaging and secure.The objective of this study was to evaluate the training effects of the VR-based multiple life skill training program on life skill perfor-mance,self-efficacy,memory,cognitive and behavioral functions via a multicenter randomized controlled trial.A total of 145 intellectual disabled participants were recruited for a randomized controlled trial with three in-tervention arms:VR(n=42);traditional(n=53);and control(n=50).The life skill tasks for the interventions included 1)grocery shopping,2)cooking,and 3)kitchen cleaning.Outcome measures were performance scores for the three tasks,self-efficacy scale,digit span score,and Frontal Assessment Battery score,graded by blinded assessors.Before-after effects of each group were evaluated using separated Wilcoxon Signed-rank tests.VR sig-nificantly improved cooking,cleaning performance,and memory span,while traditional training significantly improved shopping,cooking,and cleaning tasks.The generalized estimating equation evaluated effects between groups adjusted for age,gender and intelligence quotient(IQ).VR had significantly larger improvement effects in cooking and cleaning than the control group and memory span compared to traditional training and controls groups.IQ appeared to be a significant confounder on the training effect.Future work may consider developing artificial intelligence to customize programs depending on IQ level. | James Chung-Wai Cheung Ming Ni Andy Yiu-Chau Tam Tim Tin-Chun Chan Alyssa Ka-Yan Cheung Ocean Yu-Hong Tsang Chi-Bun Yip Wing-Kai Lam Duo Wai-Chi Wong | 2022 | Engineered Regeneration2022，3，2： | 0 |
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