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13篇 您的检索式:作者名="Timothy Townsend"
    题名 作者 年代 出处 被引量
1Brain metastasis in advanced colorectal cancer: results from the South Australian metastatic colorectal cancer (SAmCRC) registry显示文摘Objective:Brain metastasis is considered rare in metastatic colorectal cancer(mCRC);thus,surveillance imaging does not routinely include the brain.The reported incidence of brain metastases ranges from 0.6% to 3.2%.Methods:The South Australian mCRC Registry(SAmCRC)was analyzed to assess the number of patients presenting with brain metastasis during their lifetime.Due to small numbers,a descriptive analysis is presented.Results:Only 59 patients of 4,100 on the registry at the time of analysis had developed brain metastasis(1.4%).The clinical characteristics of those with brain metastasis were as follows:the median age was 65.3 years and 51% were female.Where the V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog(KRAS)mutation status of the tumor was known,the majority harbored a KRAS mutation(55%);31(53%)underwent craniotomy and 55(93%)underwent whole-brain radiotherapy.The median survival time from diagnosis of brain metastasis was 4.2 months(95% confidence interval 2.9–5.5).Patients who underwent craniotomy and radiotherapy had superior survival compared to those who underwent whole-brain radiotherapy(8.5 months vs.2.2 months,respectively).Data from the SAmCRC(a population-based registry)confirm that brain metastases are rare and the median time to development is approximately 2 years.Conclusions:Brain metastasis is a rare outcome in advanced CRC.Patients within the registry tended to be female,young in age,and harbored with higher rates of KRAS mutations.Whether routine surveillance brain scanning should be considered remains controversial given the relative rarity of developing brain metastases in mCRC and ultimately,most patients with central nervous system involvement die from their extracranial disease.Gonzalo Tapia Rico Timothy J. Price Christos Karapetis Cynthia Piantadosi Rob Padbury Amitesh Roy Guy Maddern James Moore Scott Carruthers David Roder Amanda R. Townsend 2017Cancer Biology & Medicine2017,14,4:3
2Epidemiology of neuroendocrine cancers in an Australian population显示文摘Colin Luke Timothy Price Amanda Townsend Christos Karapetis Dusan Kotasek Nimit Singhal Elizabeth Tracey David Roder 2010Cancer Causes & Control2010,,6:2
3Leaching of pollutants from reclaimed asphalt pavement显示文摘Allan S Brantley Timothy G Townsend 1999Environmental Engineering Science1999,16,2:1
4A Chemical Stain for Identifying Arsenic-Treated Wood Products显示文摘Amy L. Omae Helena M. Solo-Gabriele Timothy G. Townsend 20072007 (3-4)2007,,3:1
5Ozonation pretreatment for stabilized landfill leachate high-pressure membrane treatment 显示文摘Shrawan K Singh Chris M Moody Timothy G Townsend 2014Desalination2014,344,7:1
6Evaluation of alternative landfill cover soils for attenuating hydrogen sulfide from construction and demolition (C&D) debris landfills 显示文摘Christine Plaza Qiyong Xu Timothy Townsend 2007Journal of Environmental Management2007,,84:1
7Use of protease proteomics to discover granzyme B substrates显示文摘Andrew J. Bredemeyer R. Reid Townsend Dr. Timothy J. Ley 2005Immunologic Research (-)2005,,1:1
8The bioreactor landfill: its status and future 显示文摘Reinhart Debra R Philip T McCreanor Timothy Townsend 2002Waste Management & Research2002,,:1
9The bioreactor landfill:its status and future显示文摘Debra R Reinhart Philip T McCreanor Timothy Townsend 2002Waste Management & Research2002,20,2:1
10Liver only metastatic disease in patients with metastatic colorectal cancer: Impact of surgery and chemotherapy显示文摘Sunita Padman Robert Padbury Carol Beeke Christos S. Karapetis Sarwan Bishnoi Amanda R. Townsend Guy Maddern Timothy J. Price 2013Acta Oncologica2013,,8:1
11Heavy metal binding capacity(HMBC) of municipal solid waste landfill leachates 显示文摘Mantle L Ward Gabriel Bitton Timothy Townsend 2005Chemosphere2005,60,:1
12Rising incidence of early‐onset colorectal cancer in A ustralia over two decades: Report and review显示文摘Joanne P Young Aung Ko Win Christophe Rosty Ingrid Flight David Roder Graeme P Young Oliver Frank Graeme K Suthers Peter J Hewett Andrew Ruszkiewicz Ehud Hauben Barbara‐Ann Adelstein Susan Parry Amanda Townsend Jennifer E Hardingham Timothy J Price 2015J Gastroenterol Hepatol2015,,:1
13Sweat the Small Stuff for More C&D Debris Recovery显示文摘Timothy G Townsend Brian Messick Scott Sheridan 1999Resource Recycling1999,,2:1
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