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| 1 | Gastric calcifying fibrous tumor removed by endoscopic submucosal dissection显示文摘The World Health Organization describes calcifying fibrous tumors(CFTs) as rare, benign lesions characterized by hypocellular, densely hyalinized collagenization with lymphoplasmacytic infiltration. These tumors rarely involve the gastrointestinal(GI) tract. A routine endoscopic upper gastrointestinal screen detected a 10-mm submucosal tumor(SMT) in the lesser curvature of the lower corpus of the stomach of an apparently healthy, 37-year-old woman with no history of Helicobacter pylori infection. Endoscopic ultrasonography(EUS) localized the internally isoechoic, homogeneous SMT mainly within the submucosa. Malignancy was ruled out using endoscopic submucosal dissection(ESD). A pathological examination confirmed complete resection of the SMT, and defined a hypocellular, spindle-cell tumor with a densely hyalinized, collagenous matrix, scattered lymphoplasmacytic aggregates as well as a few psammomatous, dystrophic calcified foci. The mass was immunohistochemically positive for vimentin and negative for CD117(c-kit protein), CD34, desmin, smooth muscle actin(SMA) and S100. Therefore, the histological findings were characteristic of a CFT. To date, CFT resection by ESD has not been described. This is the first case report of a gastric calcifying fibrous tumor being completely resected by ESD after endoscopic ultrasonography. | Naotaka Ogasawara Shinya Izawa Mari Mizuno Atsushi Tanabe Tomonori Ozeki Hisatsugu Noda Emiko Takahashi Makoto Sasaki Toyoharu Yokoi Kunio Kasugai | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，9： | 8 |
| 2 | 使用ATP酶敏感钾离子通道开放剂——尼可地尔静脉给药用于冠状动脉腔内血管成形术介入治疗的药学证据显示文摘1前言动物实验研究表明,反复短暂的冠脉闭塞导致心脏抗心肌缺血的发作,这种现象被称为缺血性预处理。一些研究表明,这种预处理的效果是由于ATP敏感性钾通道的激活(KATP通道)。人类涉及经皮冠状动脉成形术(PTCA)的临床研究发现KATP通道的关闭与格列本脲防止预处理的效果通常出现在反复球囊扩张期间血管成形术模型中,表明ATP敏感性钾通道在预处理中发挥了核心作用。 | Hitoshi Matsuo Sachiro Watanabe Tomonori Segawa Shinji Yasuda Takeshi Hirose Makoto Iwama Shinichiro Tanaka Takahiko Yamaki Yukihiko Matsuno Masaaki Tomita Shinya Minatoguchi Hisayoshi Fujiwara 魏丽莎 | 2015 | 首都食品与医药2015，0，8： | 3 |
| 3 | Molecular evidence for biochemical diversification of phenolamide biosynthesis in rice plants显示文摘Two phenolamides(PAs), p-coumaroylputrescine and feruloylputrescine strongly accumulate in rice(Oryza sativa cv. Nipponbare) leaves subjected to attack of chewing and sucking herbivores. Here we identified and characterized in vitro three novel rice genes that mediated coumaroyl-Co A/feruloyl-Co A conjugation to polyamines, putrescine and agmatine. Interestingly, two genes were highly specific for their polyamine substrates, encoding putrescine N-hydroxycinnamoyltransferase and agmatine N-hydroxycinnamoyltransferase, while the third enzyme could use both polyamines and it was therefore annotated as putrescine/agmatine N-hydroxycinnamoyltransferase. All genes were preferentially expressed in rice roots and developing flowers,and in addition, the putrescine/agmatine N-hydroxycinnamoyltransferase transcripts were strongly induced by wounding in the young rice leaves. Because the wound response of this gene was only partially suppressed in the jasmonoyl-L-isoleucine deficient plants(Osjar1), it suggests that its upregulation(as well as inducible PAs in rice) may be largely independent of jasmonoyl-L-isoleucine signaling pathway. The finding of three closely related genes with a similar and/or overlapping activity in PA biosynthesis provides another striking example of rapid diversification of plant metabolism in response to environmental stresses in nature. | Kimiaki Tanabe Yuko Hojo Tomonori Shinya Ivan galis | 2016 | Journal of Integrative Plant Biology2016，58，11： | 3 |
| 4 | In-hospital monitoring of T-wave alternans in a case of amiodarone-induced torsade de pointes: clinical and methodologic insights显示文摘 | Tomonori Kawaguchi Nobuhiro Takasugi Tomoki Kubota Mieko Takasugi Hiromitsu Kanamori Hiroaki Ushikoshi Arihiro Hattori Takuma Aoyama Masanori Kawasaki Kazuhiko Nishigaki Genzou Takemura Shinya Minatoguchi Richard L. Verrier | 2012 | Europace2012，，9： | 1 |
| 5 | Relation between functional stenosis and tissue characterization of intermediate coronary plaques in patients with stable coronary heart disease显示文摘 | Shinichiro Tanaka Toshiyuki Noda Tomonori Segawa Makoto Iwama Taro Minagawa Sachiro Watanabe Shinya Minatoguchi | 2009 | Journal of Cardiology2009，，3： | 1 |
| 6 | 使用ATP酶敏感钾离子通道开放剂—尼可地尔静脉给药用于冠状动脉腔内血管成形术介入治疗的药学证据显示文摘(接4月下)4实验结果4.1每组患者的特征对两组患者的临床和生理学特征进行了总结,并在附表1呈现。观察他们的背景,包括年龄,性别,是否存在风险因素,以及造影定量评估的冠状动脉狭窄的严重程度,结果显示无显著性差异。冠状动脉成形术在所有44例患者中是成功的。 | Hitoshi Matsuo Sachiro Watanabe Tomonori Segawa Shinji Yasuda Takeshi Hirose MakotoIwamaa Shinichiro Tanaka Takahiko Yamaki Yukihiko Matsuno Masaaki Tomita Shinya Minatoguchi Hisayoshi Fujiwara 魏丽莎 | 2015 | 首都食品与医药2015，22，10： | 0 |
| 7 | Integrated view of plant metabolic defense with particular focus on chewing herbivores显示文摘Success of plants largely depends on their ability to defend against herbivores.Since emergence of the first voracious consumers,plants maintained adapting their structures and chemistry to escape from extinction.The constant pressure was further accelerated by adaptation of herbivores to plant defenses,which all together sparked the rise of a chemical empire comprised of thousands of specialized metabolites currently found in plants.Metabolic diversity in the plant kingdom is truly amazing,and although many plant metabolites have already been identified,a large number of potentially useful chemicals remain unexplored in plant bioresources.Similarly,biosynthetic routes for plant metabolites involve many enzymes,some of which still wait for identification and biochemical characterization.Moreover,regulatory mechanisms that control gene expression and enzyme activities in specialized metabolism of plants are scarcely known.Finally,understanding of how plant defense chemicals exert their toxicity and/or repellency against herbivores remains limited to typical examples,such as proteinase inhibitors,cyanogenic compounds and nicotine.In this review,we attempt summarizing the current status quo in metabolic defense of plants that is predominantly based on the survey of ubiquitous examples of plant interactions with chewing herbivores. | David Wari Takako Aboshi Tomonori Shinya Ivan Galis | 2022 | Journal of Integrative Plant Biology2022，64，2： | 0 |
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