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| 1 | Consensus of primary care in acute pancreatitis in Japan显示文摘在日本的尖锐胰腺炎的发生正在增加并且每百万张人口从 187 ~ 347 个盒子。盒子命运是 0.2% 为对温和中等,并且 9.0% 为在在 2003 的日本的严重尖锐胰腺炎。在日本的胰腺炎的专家做了与尖锐胰腺炎在病人的早管理集中于实际方面的这个文件。尖锐胰腺炎和严厉层化的正确诊断应该为尖锐胰腺炎的诊断用标准在所有病人被做并且多,因素得分系统尽早由胰的难处理的疾病的研究委员会求婚了。与尖锐胰腺炎诊断的所有病人应该在医院里被管理。血压监视,脉搏和呼吸率,体温,时时尿的体积,和血氧饱和水平在如此的病人的管理是必要的。早精力旺盛的静脉内的水和具有最前的重要性稳定循环动力学。有鸦片剂的足够的疼痛地势也是重要的。在严重尖锐胰腺炎,在一个早阶段的抗菌素的预防静脉内的管理被推荐。一旦尖锐胰腺炎的诊断被证实,朊酶禁止者的管理应该被开始。如果没有肠塞痛并且胃肠的流血的清楚的症状,从早舞台用非肠道的营养喂的肠内的联合被推荐。有严重尖锐胰腺炎的病人应该尽早被转移到 ICU 执行象朊酶的连续地区性的动脉的注入那样的特殊措施禁止者和抗菌素,和连续牙齿过敏过滤。日本政府为难处理的疾病作为关于措施的研究的工程之一为严重尖锐胰腺炎盖住医疗保健开销。 | Makoto Otsuki Masahiko Hirota Shinju Arata Masaru Koizumi Shigeyuki Kawa Terumi Kamisawa Kazunori Takeda Toshihiko Mayumi Motoji Kitagawa Tetsuhide Ito Kazuo Inui Tooru Shimosegawa Shigeki Tanaka Keisho Kataoka Hiromitsu Saisho Kazuichi Okazaki Yosikazu Kuroda Norio Sawabu Yoshifumi Takeyama | 2006 | World Journal of Gastroenterology2006，12，21： | 9 |
| 2 | Usefulness of urinary trypsinogen-2 and trypsinogen activation peptide in acute pancreatitis:A multicenter study in Japan显示文摘BACKGROUND Rapid urinary trypsinogen-2 dipstick test and levels of urinary trypsinogen-2 and trypsinogen activation peptide(TAP) concentration have been reported as prognostic markers for the diagnosis of acute pancreatitis.AIM To reconfirm the validity of all these markers in the diagnosis of acute pancreatitis by undertaking a multi-center study in Japan.METHODS Patients with acute abdominal pain were recruited from 17 medical institutions in Japan from April 2009 to December 2012. Urinary and serum samples were collected twice, at enrollment and on the following day for measuring target markers. The diagnosis and severity assessment of acute pancreatitis were assessed based on prognostic factors and computed tomography(CT) Grade of the Japanese Ministry of Health, Labour, and Welfare criteria.RESULTS A total of 94 patients were enrolled during the study period. The trypsinogen-2 dipstick test was positive in 57 of 78 patients with acute pancreatitis(sensitivity,73.1%) and in 6 of 16 patients with abdominal pain but without any evidence of acute pancreatitis(specificity, 62.5%). The area under the curve(AUC) score of urinary trypsinogen-2 according to prognostic factors was 0.704, which was highest in all parameter. The AUC scores of urinary trypsinogen-2 and TAP according to CT Grade were 0.701 and 0.692, respectively, which shows higher than other pancreatic enzymes. The levels of urinary trypsinogen-2 and TAP were significantly higher in patients with extended extra-pancreatic inflammation as evaluated by CT Grade.CONCLUSION We reconfirmed urinary trypsinogen-2 dipstick test is useful as a marker for the diagnosis of acute pancreatitis. Urinary trypsinogen-2 and TAP may be considered as useful markers to determine extra-pancreatic inflammation in acute pancreatitis. | Hiroaki Yasuda Keisho Kataoka Yoshifumi Takeyama Kazunori Takeda Tetsuhide Ito Toshihiko Mayumi Shuji Isaji Tetsuya Mine Motoji Kitagawa Seiki Kiriyama Junichi Sakagami Atsushi Masamune Kazuo Inui Kenji Hirano Ryukichi Akashi Masamichi Yokoe Yoshio Sogame Kazuichi Okazaki Chie Morioka Yasuyuki Kihara Shigeyuki Kawa Masao Tanaka Akira Andoh Wataru Kimura Isao Nishimori Junji Furuse Isao Yokota Tooru Shimosegawa | 2019 | World Journal of Gastroenterology2019，25，1： | 7 |
| 3 | Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal显示文摘 | Kazuichi Okazaki Shigeyuki Kawa Terumi Kamisawa Satoru Naruse Shigeki Tanaka Isao Nishimori Hirotaka Ohara Tetsuhide Ito Seiki Kiriyama Kazuro Inui Tooru Shimosegawa Masaru Koizumi Koichi Suda Keiko Shiratori Koji Yamaguchi Taketo Yamaguchi Masanori Sugiy | 2006 | Journal of Gastroenterology2006，，7： | 3 |
| 4 | Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreaticcancer显示文摘 | Makoto Abue Misa Yokoyama Rie Shibuya Keiichi Tamai Kazunori Yamaguchi Ikuro Sato Nobuyuki Tanaka Shin Hamada Tooru Shimosegawa Kazuo Sugamura Kennichi Satoh | 2015 | International Journal of Oncology2015，，2： | 3 |
| 5 | The revised Japanese clinical diagnostic criteria for chronic pancreatitis显示文摘 | Tooru Shimosegawa Keisho Kataoka Terumi Kamisawa Hiroyuki Miyakawa Hirotaka Ohara Tetsuhide Ito Satoru Naruse Naohiro Sata Koichi Suda Morihisa Hirota Yoshifumi Takeyama Keiko Shiratori Takashi Hatori Makoto Otsuki Yutaka Atomi Kentaro Sugano Masao Tanaka | 2010 | Journal of Gastroenterology2010，，6： | 2 |
| 6 | Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP显示文摘 | Terumi Kamisawa Kazuichi Okazaki Shigeyuki Kawa Tooru Shimosegawa Masao Tanaka | 2010 | Journal of Gastroenterology2010，，5： | 2 |
| 7 | Usefulness of the POSSUM scoring system for evaluation of the risk of pancreaticoduodectomy 显示文摘 | Shimosegawa Tooru MD Tanaka | | Suizou0，20，： | 1 |
| 8 | Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal显示文摘 | Kazuichi Okazaki Shigeyuki Kawa Terumi Kamisawa Satoru Naruse Shigeki Tanaka Isao Nishimori Hirotaka Ohara Tetsuhide Ito Seiki Kiriyama Kazuro Inui Tooru Shimosegawa Masaru Koizumi Koichi Suda Keiko Shiratori Koji Yamaguchi Taketo Yamaguchi Masanori Sugiy | 2006 | Journal of Gastroenterology2006，，7： | 1 |
| 9 | Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal显示文摘 | Kazuichi Okazaki Shigeyuki Kawa Terumi Kamisawa Satoru Naruse Shigeki Tanaka Isao Nishimori Hirotaka Ohara Tetsuhide Ito Seiki Kiriyama Kazuro Inui Tooru Shimosegawa Masaru Koizumi Koichi Suda Keiko Shiratori Koji Yamaguchi Taketo Yamaguchi Masanori Sugiy | 2006 | Journal of Gastroenterology2006，，7： | 1 |
| 10 | Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP显示文摘 | Terumi Kamisawa Kazuichi Okazaki Shigeyuki Kawa Tooru Shimosegawa Masao Tanaka | 2010 | Journal of Gastroenterology2010，，5： | 1 |
| 11 | Neoadjuvant chemotherapy for high-grade advanced gastric cancer显示文摘 | Yutaka Yonemura M.D. Tosiharu Sawa M.D. Kazuo Kinoshita M.D. Nobuo Matsuki M.D. Sachio Fushida M.D. Sigehiro Tanaka M.D. Shigekazu Ohoyama M.D. Tooru Takashima M.D. Hironobu Kimura M.D. Tooru Kamata M.D. Takashi Fujimura M.D. Kazuo Sugiyama M.D. Kouzou Sh | 1993 | World Journal of Surgery1993，，2： | 1 |
| 12 | Amendment of the Japanese Consensus Guidelines for Autoimmune Pancreatitis, 2013 III. Treatment and prognosis of autoimmune pancreatitis显示文摘 | Terumi Kamisawa Kazuichi Okazaki Shigeyuki Kawa Tetsuhide Ito Kazuo Inui Hiroyuki Irie Takayoshi Nishino Kenji Notohara Isao Nishimori Shigeki Tanaka Toshimasa Nishiyama Koichi Suda Keiko Shiratori Masao Tanaka Tooru Shimosegawa | 2014 | Journal of Gastroenterology2014，，6： | 1 |
| 13 | Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal显示文摘 | Kazuichi Okazaki Shigeyuki Kawa Terumi Kamisawa Satoru Naruse Shigeki Tanaka Isao Nishimori Hirotaka Ohara Tetsuhide Ito Seiki Kiriyama Kazuro Inui Tooru Shimosegawa Masaru Koizumi Koichi Suda Keiko Shiratori Koji Yamaguchi Taketo Yamaguchi Masanori Sugiy | 2006 | Journal of Gastroenterology2006，，7： | 1 |
| 14 | Surgery for chronic pancreatitis decreases the risk for pancreatic cancer: A multicenter retrospective analysis显示文摘 | Junji Ueda Masao Tanaka Takao Ohtsuka Shoji Tokunaga Tooru Shimosegawa | 2012 | Surgery2012，，： | 1 |
| 15 | Influence of composition ratio on properties of Cu2ZnSnS4 thin films fabricated by co-evaporation显示文摘 | Tooru Tanaka Akihiro Yoshida Daisuke Saiki | 2010 | Thin Solid Films2010，518，： | 1 |
| 16 | A Clinicopathologic Study of 30 Patients with Paget’s Disease of the Vulva显示文摘 | Shoji Kodama Tooru Kaneko Mari Saito Norio Yoshiya Shigeru Honma Kenichi Tanaka | 1995 | Gynecologic Oncology1995，，1： | 1 |
| 17 | Usefulness of the POSSUM scoring system for evaluation of the risk of pancreaticoduodectomy显示文摘 | Shimosegawa Tooru MD Tanaka | 2005 | Suizou2005，20，5： | 1 |
| 18 | Growth properties of gallium oxide on sapphire substrate by plasma-assisted pulsed laser deposition显示文摘Gallium oxide was deposited on a c-plane sapphire substrate by oxygen plasma-assisted pulsed laser deposition(PLD).An oxygen radical was generated by an inductive coupled plasma source and the effect of radio frequency(RF)power on growth rate was investigated.A film grown with plasma assistance showed 2.7 times faster growth rate.X-ray diffraction and Raman spectroscopy analysis showedβ-Ga2 O3 films grown with plasma assistance at 500℃.The roughness of the films decreased when the RF power of plasma treatment increased.Transmittance of these films was at least 80%and showed sharp absorption edge at 250 nm which was consistent with data previously reported. | Congyu Hu Katsuhiko Saito Tooru Tanaka Qixin Guo | 2019 | Journal of Semiconductors2019，40，12： | 1 |
| 19 | Up-Regulation of MSX2 Enhances the Malignant Phenotype and Is Associated with Twist 1 Expression in Human Pancreatic Cancer Cells显示文摘 | Kennichi Satoh Shin Hamada Kenji Kimura Atsushi Kanno Morihisa Hirota Jun Umino Wataru Fujibuchi Atsushi Masamune Naoki Tanaka Koh Miura Shinichi Egawa Fuyuhiko Motoi Michiaki Unno Barbara K. Vonderhaar Tooru Shimosegawa | 2008 | The American Journal of Pathology2008，，4： | 1 |
| 20 | Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal显示文摘 | Kazuichi Okazaki Shigeyuki Kawa Terumi Kamisawa Satoru Naruse Shigeki Tanaka Isao Nishimori Hirotaka Ohara Tetsuhide Ito Seiki Kiriyama Kazuro Inui Tooru Shimosegawa Masaru Koizumi Koichi Suda Keiko Shiratori Koji Yamaguchi Taketo Yamaguchi Masanori Sugiy | 2006 | Journal of Gastroenterology2006，，7： | 1 |
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