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| 1 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017,9,1: | 2 |
| 2 | Alteration of tomato fruit quality by root inoculation with plant growth-promoting rhizobacteria (PGPR): Bacillus subtilis BEB-13bs显示文摘 | Hortencia G M Victor O | 2007 | Scientia Horticulturae2007,113,10: | 1 |
| 3 | Directionally Solidified Eutectic Ceramic Oxides显示文摘 | Javier L L Victor M O | 2006 | Progress in Materials Scicnce2006,51,6: | 1 |
| 4 | Sistemas transcurrentes de escala litosferica en el Sur del Peru显示文摘 | Thierry S Javier J Victor C William M Conrado B Michel F Pierrick R Harmuth A Jorge A Luis C Alexander F Ivanoff I Omar L Mirian M Paola M Francis O Yovani O Adan P and Rildo R | | 0,,05: | 1 |
| 5 | Baculovirus Alkaline Nuclease Possesses a 5'→3' Exonuclease Activity and Associates with the DNA-Binding Protein LEF-3显示文摘 | Victor S M Kazuhiro O George F R | 2003 | Journal of Virology2003,74,: | 1 |
| 6 | Diffusion as a toolof measuring temperature inside a capillary 显示文摘 | Michael U M Sahar J Victor O | 2008 | Analyt Chem2008,8,: | 1 |
| 7 | Helicobacter pylori Eradication and Change in Markers of Iron Stores Among Non–iron-deficient Children in El Paso, Texas: An Etiologic Intervention Study显示文摘 | Victor M Cardenas Carmen A Prieto-Jimenez Zuber D Mulla Jose O Rivera Delfina C Dominguez David Y Graham Melchor Ortiz | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011,,3: | 1 |
| 8 | Glottal source biometricalsignature for voice pathology detection显示文摘 | PEDRO G V ROBERTO F B VICTORIA R B VICTOR N L AGUSTIN A M LUIS M M F RAFAEL M O JUAN I G L | 2009 | Speech Communication2009,51,9: | 1 |
| 9 | Modulation of coherence and polarization using liquid crystal spatial light modulators显示文摘 | Andrey S O Gabriel M N Victor A | 2009 | Optics Express2009,17,7: | 1 |
| 10 | Alteration of tomato fruit quality by root inoculation with plant growth-promoting rhizobacteria (PGPR):Bacillus subtilis BEB-13bs显示文摘 | HORTENCIA G M VICTOR O | 2007 | Sci Hortic2007,113,1: | 1 |
| 11 | Refined models for the optimal design of adaptive structures using simulated annealing显示文摘 | CORREIA Victor M F SOARES Cristov? o M M SOARES C A M | 2001 | Composite Structures2001,54,3: | 1 |
| 12 | Visible light photocatalytic activities of S-doped TiO2-Fea^3+ in aqueous and gas phase显示文摘 | VICTOR M MMNENDEZ F DETLEF W BAHNEMAN N TERUHIA O | 2011 | Applied Catalysis B: Environmental2011,103,: | 1 |
| 13 | Alteration of tomato fruit quality by root inoculation with plant growth-promoting rhizobacteria (PGPR):Bacillus subtilis BEB-13bs显示文摘 | Hortencia G M V Victor O P | 2007 | Scientia Horticulturae2007,113,: | 1 |
| 14 | Dilute-acid hydrolysis of sugarcane bagasse at varying conditions 显示文摘 | LARISSA C VICTOR T O S GEORGE J M R | 2002 | Appl Biochem Biotechnol2002,,: | 1 |
| 15 | Directionally Solidified Eutectie Ceramic Oxides显示文摘 | Avier L L Victor M O | 2006 | Progress in Materials Science2006,51,6: | 1 |
| 16 | Scopolamine,anisodamine and hyoscyamine production by Brugmansia Candidahairy root cultures in bioreactors 显示文摘 | ALEJANDRA B C ANGELA M O VICTOR DB | 2010 | Process Biochemistry2010,45,11: | 1 |
| 17 | The roles of amylose and amylopectin in the gelationand retrogradation of starch 显示文摘 | Mervyn J M Victor J M Paul D O | 1985 | Carbohydr Res1985,135,: | 1 |
| 18 | The kinetics of zinc silicate leaching in sodium hydroxide 显示文摘 | SANTOS F M F PINA P S PORCARO R VICTOR A O CAELOS A S VERSIANE A L | 2010 | Hydrometallurgy2010,102,14: | 1 |
| 19 | Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction. | Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) | 2021 | Stroke & Vascular Neurology2021,6,4: | 0 |
| 20 | Sub-percent precision measurement of neutrino oscillation parameters with JUNO显示文摘JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters. | Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem 安丰鹏 安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste 白伟东 Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩 蔡啸 蔡严克 蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚 曹国富 曹俊 Rossella Caruso Cédric Cerna Chi Chan 常劲帆 Yun Chang 陈国明 陈平平 Po-An Chen 陈少敏 Xurong Chen 陈义学 陈羽 陈志源 陈梓康 程捷 程雅苹 Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智 邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich Marcos Dracos Frédéric Druillole 杜然 杜书先 Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan 樊磊 方建 方文兴 Marco Fargetta Dmitry Fedoseev 费政勇 Li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 高峰 Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar 龚光华 宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov 顾旻皓 谷肖飞 古宇 关梦云 管宇铎 Nunzio Guardone 郭聪 郭竞渊 郭万磊 Xinheng Guo 郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han 何苗 Wei He Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强 侯少静 Yee Hsiung Bei-Zhen Hu 胡航 Jianrun Hu 胡俊 胡守扬 胡涛 胡宇翔 胡焯钧 黄桂鸿 黄翰雄 黄凯旋 黄文昊 Xin Huang 黄性涛 黄永波 惠加琪 霍雷 霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Ignacio Jeria 季筱璐 贾慧慧 贾俊基 蹇司玉 蒋荻 蒋炜 江晓山 荆小平 Cécile Jollet Jari Joutsenvaara Leonidas Kalousis Philipp Kampmann 康丽 Rebin Karaparambil Narine Kazarian Amina Khatun Khanchai Khosonthongkee Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Victor Lebrin Frederic Lefevre 雷瑞庭 Rupert Leitner Jason Leung Daozheng Li 李德民 李飞 李福乐 李高嵩 Huiling Li 李梦朝 李民 李楠 Nan Li 李清江 李茹慧 李瑞 黎山峰 李涛 李腾 李卫东 李卫国 李笑梅 李小男 李兴隆 李仪 李依宸 李玉峰 Zepeng Li 李兆涵 李志兵 李紫源 李宗海 梁浩 梁昊 廖佳军 Ayut Limphirat Guey-Lin Lin 林盛鑫 林韬 凌家杰 Ivano Lippi 刘芳 刘海东 刘昊天 刘宏邦 刘红娟 刘洪涛 Hui Liu 刘江来 刘金昌 刘敏 刘倩 刘钦 Runxuan Liu 刘树彬 刘术林 刘小伟 刘熙文 Yan Liu Yunzhe Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo 陆川 路浩奇 陆景彬 吕军光 路书祥 Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Arslan Lukanov Daibin Luo Fengjiao Luo 罗光 罗舒 罗武鸣 罗晓杰 Vladimir Lyashuk 马帮争 马冰 马秋梅 马斯 马骁妍 马续波 Jihane Maalmi 麦景宇 Yury Malyshkin Roberto Carlos Mandujano Fabio Mantovani Francesco Manzali 冒鑫 冒亚军 Stefano M.Mari Filippo Marini Cristina Martellini Gisele Martin-Chassard Agnese Martini Matthias Mayer Davit Mayilyan Ints Mednieks Artur Meinusch 孟月 Anselmo Meregaglia Emanuela Meroni David Meyhö Mauro Mezzetto Jonathan Miller Lino Miramonti Marta Colomer Molla Paolo Montini Michele Montuschi Axel Müller Massimiliano Nastasi Dmitry V.Naumov Elena Naumova Diana Navas-Nicolas Igor Nemchenok Minh Thuan Nguyen Thi 宁飞鹏 宁哲 Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Rainer Othegraven Alessandro Paoloni Sergio Parmeggiano 裴亚田 Luca Pelicci Nicomede Pelliccia 彭安国 彭海平 彭宇 彭昭缘 Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Oliver Pilarczyk Luis Felipe Piñeres Artyom Popov Pascal Poussot Ezio Previtali 齐法制 祁鸣 钱森 钱小辉 钱圳 乔浩 秦中华 丘寿康 Gioacchino Ranucci Neill Raper Reem Rasheed Alessandra Re Henning Rebber Abdel Rebii Mariia Redchuk 任斌 任杰 Barbara Ricci Mariam Rifai Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec 阮锡超 Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Simone Sanfilippo Anut Sangka Utane Sawangwit Julia Sawatzki Michaela Schever Cédric Schwab Konstantin Schweizer Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Zhuang Shao Vladislav Sharov Arina Shaydurova 石京燕 史娅楠 Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Sergey Sokolov Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov OndřejŠrámek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin 苏俊 孙世峰 孙希磊 孙勇杰 孙永昭 孙正阳 Narumon Suwonjandee Michal Szelezniak 唐健 唐强 唐泉 唐晓 Vidhya Thara Hariharan Eric Theisen Alexander Tietzsch Igor Tkachev Tomas Tmej Marco Danilo Claudio Torri Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Alexandros Tsagkarakis Cristina Tuve Nikita Ushakov Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cornelius Moritz Vollbrecht Cristina Volpe Katharina Von Sturm Vit Vorobel Dmitriy Voronin Lucia Votano Pablo Walker 王彩申 Chung-Hsiang Wang 王恩 王国利 王坚 王俊 汪璐 Meifen Wang 王孟 Meng Wang 王瑞光 王思广 王维 王为 王文帅 王玺 王湘粤 王仰夫 王耀光 王毅 王义 王贻芳 王元清 Yuman Wang 王喆 王铮 王志民 Zongyi Wang Apimook Watcharangkool 魏微 魏巍 韦雯露 魏亚东 温凯乐 温良剑 Christopher Wiebusch 黄振辉 Bjoern Wonsak 吴帝儒 吴群 吴智 Michael Wurm Jacques Wurtz Christian Wysotzki 习宇飞 夏冬梅 Xiang Xiao 谢小川 谢宇广 Zhangquan Xie 辛钊 邢志忠 续本达 徐程 徐东莲 徐繁荣 许杭锟 徐吉磊 徐晶 徐美杭 徐音 闫保军 Taylor Yan Wenqi Yan 严雄波 Yupeng Yan 杨长根 杨成峰 Huan Yang 杨洁 杨雷 杨晓宇 Yifan Yang 姚海峰 叶佳璇 叶梅 叶子平 Frédéric Yermia Na Yin 尤郑昀 俞伯祥 余炽业 喻纯旭 余泓钊 于淼 于向辉 于泽源 于泽众 袁岑溪 袁成卓 袁影 袁振雄 岳保彪 Noman Zafar Vitalii Zavadskyi 曾珊 曾婷轩 曾裕达 占亮 张爱强 张斌 张斌婷 张飞洋 Guoqing Zhang 张宏浩 张家梁 张家文 张杰 Jin Zhang 张景波 张金楠 Mohan Zhang 张鹏 张清民 张石其 张澍 张涛 张晓梅 张鑫 张玄同 Xueyao Zhang 张银鸿 张易于 张永鹏 张宇 张圆圆 张玉美 张振宇 张志坚 Fengyi Zhao 赵洁 赵荣 赵润泽 赵书俊 Dongqin Zheng 郑华 郑阳恒 Weirong Zhong 周静 周莉 周楠 周顺 周彤 周详 朱江 朱景森 朱康甫 朱科军 朱志航 庄博 庄红林 宗亮 邹佳恒 | 2022 | Chinese Physics C2022,46,12: | 0 |