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| 1 | Nerve growth factor and injured peripheral nerve regeneration显示文摘Nerve growth factor (NGF) exhibits many biological activities,such as supply of nutrients,neuroprotection,and the generation and rehabilitation of injured nerves. The neuroprotective and neurotrophic qualities of NGF are generally recognized. NGF may enhance axonal regeneration and myelination of peripheral nerves,as well as cooperatively promote functional recovery of injured nerves and limbs. The clinical efficacy of NGF and its therapeutic potentials are reviewed here. This paper also reviews the latest NGF research developments for repairing injured peripheral nerve,thereby providing scientific evidence for the appropriate clinical application of NGF. | Endong Shi Bingchen Wang Qingshan Sun | 2008 | Neural Regeneration Research2008，3，11： | 10 |
| 2 | Remarkable anisotropic phonon response in uniaxially strained few-layer black phosphorus显示文摘黑磷(BP ) 是一个好候选人因为学习紧张在 graphene 和转变金属 dichalcogenides 以外在 twodimensional (2D ) 上完成材料。这因为它支撑高紧张和源于它的唯一的皱起的结构的显著地各向异性的机械性质的特别能力。我们这里调查格子的依赖在由在原处做作的拉曼的单轴地做作的很少层 BP 的结晶的取向上的震动的频率光谱学。out-of-plane A 1 而, g 模式对沿着近扶手椅的方向的单轴的紧张敏感在里面飞机 B 2g 和 A 2 g 模式是敏感的在近之字形的方向拉紧。为使用离开这些方向的单轴的种类,所有三个声子模式是线性地 redshifted。我们的试验性的观察被对 BP 的结构的性质的单轴的张力的紧张的各向异性的影响用密度解释功能的理论。这研究表明由单轴的紧张的在 BP 的在里面飞机和 out-of-plane 声子模式的选择调节的可能性并且使紧张工程成为一条有希望的大街为广泛地 modulating 2D 材料的光、机械的性质。 | Yanlong Wang Chunxiao Cong Ruixiang Fei Weihuang Yang Yu Chen Bingchen Cao Li Yang Ting Yu | 2015 | Nano Research2015，8，12： | 9 |
| 3 | An efficient data compression technique based on BPDN for scattered fields from complex targets显示文摘Dear editor,For complex targets,the scattered fields vary rapidly with frequency or aspect angle owing to diverse scattering mechanisms[1].To comprehensively learn the characteristics of a target’s signature,a large number of radar cross section(RCS) | Xiangyin QUAN Bingchen ZHANG Zhengdao WANG Chao GAO Yirong WU | 2017 | Science China(Information Sciences)2017，60，10： | 5 |
| 4 | Analysis of Oblique Wave Interaction with a Comb-Type Caisson Breakwater显示文摘This study develops an analytical solution for oblique wave interaction with a comb-type caisson breakwater based on linear potential theory. The fluid domain is divided into inner and outer regions according to the geometrical shape of breakwater. By using periodic boundary condition and separation of variables, series solutions of velocity potentials in inner and outer regions are developed. Unknown expansion coefficients in series solutions are determined by matching velocity and pressure of continuous conditions on the interface between two regions. Then, hydrodynamic quantities involving reflection coefficients and wave forces acting on breakwater are estimated. Analytical solution is validated by a multi-domain boundary element method solution for the present problem. Diffusion reflection due to periodic variations in breakwater shape and corresponding surface elevations around the breakwater are analyzed. Numerical examples are also presented to examine effects of caisson parameters on total wave forces acting on caissons and total wave forces acting on side plates. Compared with a traditional vertical wall breakwater, the wave force acting on a suitably designed comb-type caisson breakwater can be significantly reduced. This study can give a better understanding of the hydrodynamic performance of comb-type caisson breakwaters. | WANG Xinyu LIU Yong LIANG Bingchen | 2018 | Journal of Ocean University of China2018，17，2： | 3 |
| 5 | Microstructural evolution and energetic characteristics of TiZrHfTa_(0.7)W_(0.3)high-entropy alloy under high strain rates and its application in high-velocity penetration显示文摘Energetic structural materials(ESMs)integrated a high energy density and rapid energy release with the ability to serve as structural materials.Here,a novel triple-phase TiZrHfTa_(0.7)W_(0.3)high-entropy alloy(HEA)was fabricated and investigated as a potential ESM.A hierarchical microstructure was obtained with a main metastable body-centered-cubic(BCC)matrix with distributed Ta-W-rich BCC precipitates of various sizes and interwoven hexagonal close-packed(HCP)lamellar nano-plates.The compressive me-chanical properties were tested across a range of strain rates and demonstrated a brittle-to-ductile tran-sition as the strain rate increased while maintaining a high ultimate strength of approximately 2.5 GPa.This was due to the phase transformation from metastable matrix BCC to HCP structures.In addition,during the dynamic deformation,metal combustion originating from the failure surface was observed.Furthermore,the composition of the fragments was studied,and the results indicated that the addition of tungsten promoted combustion.Finally,the potential application of this HEA was evaluated by high-velocity penetration tests,and the results were compared to other typical structural materials for pene-trators and bullets.A comparison was conducted by assessing the geometries of the penetration channel employing two dimensionless parameters normalized by the projectile size,representing longitudinal and lateral damage,respectively.The normalized depth of the TiZrHfTa_(0.7)W_(0.3)HEA projectile was comparable to those of the other investigated materials,but the normalized diameter was the largest,showing an excellent ability to deliver lateral damage. | Weiqi Tang Kun Zhang Tianyu Chen Qiu Wang Bingchen Wei | 2023 | Journal of Materials Science & Technology2023，，1： | 3 |
| 6 | Tunable excitonic emission of monolayer WS2 for the optical detection of DNA nucleobases显示文摘 | Shun Feng Chunxiao Cong Namphung Peimyoo Yu Chen Jingzhi Shang Chenji Zou Bingchen Cao Lishu Wu Jing Zhang Mustafa Eginligil Xingzhi Wang Qihua Xiong Arundithi Ananthanarayanan Peng Chen Baile Zhang Ting Yu | 2018 | Nano Research2018，11，3： | 1 |
| 7 | Pt/3D-graphene/FTO electrodes: Electrochemical preparation and their enhanced electrocatalytic activity显示文摘 | Shaolin Yang Yongwei Huang Wei Zhu Bingchen Deng Hong Wang Zihan Zhang Pengfei Bao Guanzhong Wang | 2014 | International Journal of Hydrogen Energy2014，，27： | 1 |
| 8 | Domain structure of hard magnetic NdAlFeCo bulk metallic glass显示文摘Magnetic domain structure of hard magnetic Nd60Al10Fe20Co10 bulk metallic glass (BMG) has been studied by using magnetic force microscopy. In the magnetic force images it is shown that the exchange interaction type magnetic domains with a period of about 360 nm do exist in the BMG, which is believed to be associated with the appearance of hard-magnetic properties in this system. As the scale of the magnetic domain is much larger than the size of the short-range ordered atomic clusters existing in the BMG, it is believed that the large areas of magnetic contrast are actually a collection of a group of clusters aligned in parallel by strong exchange coupling interaction. After fully crystallization, the BMG exhibits paramagnetism. No obvious magnetic contrast is observed in the magnetic force images of fully crystallized samples, except for a small quantity of ferromagnetic crystalline phase with low coercivity and an average size of 900 nm. | WEI Bingchen WANG Weihua PAN Mingxiang HAN Baoshan ZHANG Zhenrong HU Wenrui | 2001 | Chinese Science Bulletin2001，46，19： | 1 |
| 9 | The Mechanism of Groundwater Salinization and Its Control in the Yaoba Oasis,Inner Mongolia显示文摘The arid area is one of the most concerned areas among the water resources researchers and economists. Northwest China will be an important developing region of China in the 21st century. Yaoba is a well-irrigation oasis within this arid area, which is located in the Alxa area west of the Helan Mountains and next to the Tengger desert in the east. It has contributed greatly to the local stock raising and agriculture since its development in 1970. However, the groundwater which the oasis depends on to survive has been getting salinized gradually and more serious in recent years.A comprehensive study was carried out using the methods of groundwater environment isotope analysis, lithofaci-es and palaeogeography, calculations of water-rock interaction and the existing form of chemical components in groundwater etc. It has been found that the salinization of groundwater is mainly caused by reinfiltration water solving the salt in soil which is deposited simultaneously with the sediments and accumulated in | WANG Bingchen QIU Hanxue XU Qian ZHENG Xilai LIU Guanqun | 2000 | Acta Geologica Sinica(English Edition)2000，74，2： | 1 |
| 10 | Microstructure and mechanical properties of a novel Zr-based bulk metallic glass composite显示文摘Zr48.5Cu46.5Al5 bulk metallic glass (BMG) com- posites with diameters of 3 and 4 mm were prepared through suction casting in an arc melting furnace by modulating the alloy composition around the monothetic BMG composition of the high glass forming ability. Microstructural charac- terization reveals that the composites contain micron-sized CuZr phase with martensite structure, as well as nano-sized Zr2Cu crystalline particles and Cu10Zr7 plate-like phase em- bedded in an amorphous matrix. Room temperature com- pression tests showed that the composites exhibited signifi- cant strain hardening and obvious plastic strain of 7.7% for 3 mm and 6.4% for 4 mm diameter samples, respectively. | SUN Yufeng WANG Yuren GUO Jian WEI Bingchen LI Weihuo | 2005 | Chinese Science Bulletin2005，50，24： | 1 |
| 11 | Preparation of Cu-based Bulk Metallic Glass Matrix Composites显示文摘在 situ 包含的金属性的玻璃(BMG ) 矩阵 composites 形成了的 Cu_(47 )Ti_(34 )Zr_(11 ) Ni_8 体积 TiC 粒子和 delta-TiCu 树突阶段被铜开发模子演员组。composites 的热稳定性和微观结构被调查。房间温度耐压试验表明合成样品展出更高的破裂力量和 0.2 percent-0.5 百分比的不同塑料紧张,把 Ti_(34 ) 与 correspondingCu_(47 ) 的作比较 Zr_(11 ) Ni_8 整体的 BMG。 | Yufeng SUN Yuren WANG Bingchen WEI Weihuo LI | 2006 | Journal of Materials Science & Technology2006，22，1： | 1 |
| 12 | Targeting self-enhanced ROS-responsive artesunatum prodrug nanoassembly potentiates gemcitabine activity by down-regulating CDA expression in cervical cancer显示文摘Prodrug self-delivery carriers with targeting that specifically responded to tumor microenvironments have good potential to improve the application dilemma of approved clinical therapeutic drugs(systemic distribution and side effects).It's noted the conversion of gemcitabine(GEM)to inactive ingredients under the action of cytidine deaminase(CDA)during metabolism in vivo limits its clinical effect.A high level of reactive oxygen species(ROS)results in a high level of oxidative stress in tumor cells,which changes the expression of CDA and optimizes the metabolism of GEM in vivo and overcome drug resistance.In this study,the ROS responsive and ROS self-supplied prodrug of artemisia(ART)-thioacetal bond(TK)-GEM was synthesized and self-vectors based on ART-TK-GEM(TK@FA NPs)was prepared by using nano precipitation.ROS responsive characteristics ensure specific release of prodrugs in tumor cells with high level of ROS thereby reducing side effects on normal cells and tissues.The endogenous ROS and newly generated ROS by ART can reduce the expression of CDA and optimizes the metabolism of GEM,and the accumulated ROS can also induce apoptosis of tumor cells,realizing synergistic anti-tumor effect of chemical drugs and traditional Chinese medicines.This paper proposes a simple method by using clinically approved drugs to improve the insufficient effect of existing chemotherapy and overcome resistance,which has potential to appropriately shorten the drug development cycle and accelerate the clinical investigation of drugs. | Shengtao Wang Kunyi Yu Zhiyu Yu Bingchen Zhang Chaojie Chen Ling Lin Zibo Li Zhongjun Li Yuhua Zheng Zhiqiang Yu | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 13 | Polyetherimide functionalized carbon dots with enhanced red emission in aqueous solution for bioimaging显示文摘Red emissive carbon dots(CDs)are highly desired for biological applications.However,serious luminescence quenching of red emissive CDs in aqueous solution greatly hinders their application in high performance biological imaging.Herein,we reported a facile strategy to realize enhanced red emission of CDs in aqueous solution by surface modification with polyetherimide(PEI)via microwave heating method.High photoluminescence quantum yield(PLQY)of 25%was realized from the PEI functionalized CDs(CDs@PEI)in aqueous solution.The proposed PEI functionalization strategy not only protects the red emission against water molecules quenching,but also reverses the surface charges from negativity to positivity to promote cellular uptake of CDs,leading to clear cell imaging in red fluorescence region.More important,CDs@PEI exhibits much better photostability than commercial red emissive dye(MitoT racker red)in cell fluorescent imaging.Potential application of CDs@PEI on fast staining of cells for clonogenic assay has also been demonstrated. | Liming Wang Bingzhe Wang Enshan Liu Yunyang Zhao Bingchen He Chunfei Wang Guichuan Xing Zikang Tang Yinning Zhou Songnan Qu | 2022 | Chinese Chemical Letters2022，33，8： | 0 |
| 14 | Electrical field tuning of magneto-Raman scattering in monolayer graphene显示文摘在这个工作,我们报导在磁场下面在单层 graphene 磁电机声子回声调节直到 9 T 的电场。搬运人集中罐头急速地影响 G E,这被发现 < 潜水艇 class= “ a-plus-plus ” > 对通过显著磁电机声子回声 MPR 的一个变化磁场的 2g 声子反应。在负责中立或稍微做的单层 graphene,精力和 E 的线宽度 < 潜水艇 class= “ a-plus-plus ” > 2g 声子表演有磁场的清楚的变化。这被归因于在 magnetoexcitations 和 E 之间的磁电机声子回声 < 潜水艇 class= “ a-plus-plus ” > 2g 声子。相反,当单层 graphene 的费密水平是远的离开迪拉克点时, G 乐队显示出弱磁性的依赖并且展出对称的线形状。这建议在 4 T 附近联合的磁电机声子由于堵住的泡利不相容原理被关上了内部 -- 四轮马车水平刺激。而且, G 乐队不对称现象由在激子的许多身体状态和 E 之间的 Fano 回声引起了 < 潜水艇 class= “ a-plus-plus ” > 2g 声子被观察。这个工作提供一个方法与一个外部电场通过 magneto-Raman 光谱学学习材料的 magnetoexcitation 声子相互作用。 | Xiaonan Shen Caiyu Qiu Bingchen Cao Chunxiao Cong Weihuang Yang Haomin Wang Ting Yu | 2015 | Nano Research2015，8，4： | 0 |
| 15 | Stabilizing SEI by cyclic ethers toward enhanced K^(+) storage in graphite显示文摘The poor cycling stability of graphite in traditional ester electrolyte limits its applications as anodes for potassium ion batteries(KIBs).Herein,we demonstrate that the introduction of cyclic ether co-solvents into ester electrolytes can remarkably enhance the cycling stability of graphite anodes.The graphite anode in ester electrolyte with cyclic ether could achieve a reversible capacity of 196.1 m Ah g^(-1) after 100 cycles at 0.3 C(1 C=280 m A g^(-1)),about three times higher than those in ester electrolytes with or without linear ether.Compared with the SEI formed in ester electrolytes,the addition of tetrahydrofuran promotes the generation of K_(2)CO_(3) and ethylene oxide oligomers(PEO),of which the K_(2)CO_(3) is expected to be more conductive and PEO is mechanically robust.The more uniform,conductive and stable solid electrolyte interphases(SEIs)on graphite in electrolytes with cyclic ethers contribute to the enhancement of the electrochemical performances of graphite.This work provides a novel design of commercialized electrolytes to achieve high-performance anodes for KIBs,which potentially accelerates the development of KIBs. | Jiesong Zhang Jian-Fang Wu Zixing Wang Ying Mo Wang Zhou Yufan Peng Bingchen He Kuikui Xiao Shi Chen Chaohe Xu Jilei Liu | 2022 | Journal of Energy Chemistry2022，31，8： | 0 |
| 16 | Intrinsic excitonic emission and valley Zeeman splitting in epitaxial MS2(M=Mo and W)monolayers on hexagonal boron nitride显示文摘Two-dimensional (2D)semiconductors,represented by 2D transition metal dichalcogenides (TMDs),exhibit rich valley physics due to strong spin-orbit/ spin-valley coupling.The most common way to probe such 2D systems is to utilize optical methods,which can monitor light emissions from various excitonic states and further help in understanding the physics behind such phenomena. Therefore,2D TMDs with good optical quality are in great demand.Here,we report a method to directly grow epitaxial WS2 and MoS2 monolayers on hexagonal boron nitride (hBN)flakeswith a high yield and high optical quality;these monolayers show better intrinsic light emission features than exfoliated monolayers from natural crystals.For the first time,the valley Zeeman splitting of WS2 and MoS2 monolayers on hBN has been visualized and systematically investigated. This study paves a new way to produce high optical quality WS2and MoS2 monolayers and to exploit their intrinsic properties in a multitude of applications. | Chunxiao Cong Chenji Zou Bingchen Cao Lishu Wu Jingzhi Shahg Haomin Wang Zhijun Qiu Laigui Hu Pengfei Tian Ran Liu Ting Yu | 2018 | Nano Research2018，11，12： | 0 |
| 17 | A New Geochemical Reaction Model for Groundwater Systems显示文摘Through a survey of the literature on geology, hydrogeology and hydrogeochemistry, this paper presents a hydrogeochemical model for the groundwater system in a dross-dumping area of the Shandong Aluminium Plant. It is considered that the groundwater-bearing medium is a mineral aggregate and that the interactions between groundwater and the groundwater-bearing medium can be described as a series of geochemical reactions. On that basis, the principle of minimum energy and the equations of mass balance, electron balance and electric neutrality are applied to construct a linear programming mathematical model for the calculation of mass transfer between water and rock with the simplex method. | ZHENG Xilai Institute of Geosciences, Qingdao Ocean University, Qingdao 266003, Shandongand WANG Bingchen Comprehensive Institute of Geotechnical Survey, Beijing 100007 | 2000 | Acta Geologica Sinica(English Edition)2000，74，2： | 0 |
| 18 | Structural adaptive and optimal speckle filtering in multilook full polarimetric SAR images显示文摘A novel approach is proposed for speckle reduction in multilook full polarimetric SAR images. In contrast to others, this approach adopts an enhanced structure detection method to estimate the parameters of the polarimetric covariance matrix for the multilook polarimetric whitening filtering (MPWF) algorithm and thus a structural adaptive and optimal speckle filter is developed. To evaluate the present approach, NASA SIR-C/X-SAR, L band, four-look processed polarimetric SAR data of the Tian-Mountain Forest is used for simulation. Experimental results demonstrate the effectiveness of this novel filtering algorithm in case of both speckle reduction and preservation of texture information. Comparisons with other methods are also made. | Sun Nan Zhang Bingchen Wang Yanfei | 2007 | Journal of Systems Engineering and Electronics2007，18，2： | 0 |
| 19 | Self-oxygenated co-assembled biomimetic nanoplatform for enhanced photodynamic therapy in hypoxic tumor显示文摘Photodynamic therapy(PDT)has shown great application potential in cancer treatment and the important manifestation of PDT in the inhibition of tumors is the activation of immunogenic cell death(ICD)effects.However,the strategy is limited in the innate hypoxic tumor microenvironment.There are two key elements for the realization of enhanced PDT:specific cellular uptake and release of the photosensitizer in the tumor,and a sufficient amount of oxygen to ensure photodynamic efficiency.Herein,self-oxygenated biomimetic nanoparticles(CS@M NPs)co-assembled by photosensitizer prodrug(Ce6-S-S-LA)and squalene(SQ)were engineered.In the treatment of triple negative breast cancer(TNBC),the oxygen carried by SQ can be converted to reactive oxygen species(ROS).Meanwhile,glutathione(GSH)consumption during transformation from Ce6-S-S-LA to chlorin e6(Ce6)avoided the depletion of ROS.The co-assembled(CS NPs)were encapsulated by homologous tumor cell membrane to improve the tumor targeting.The results showed that the ICD effect of CS@M NPs was confirmed by the significant release of calreticulin(CRT)and high mobility group protein B1(HMGB1),and it significantly activated the immune system by inhibiting the hypoxia inducible factor-1alpha(HIF-1α)-CD39-CD73-adenosine a2a receptor(A2AR)pathway,which not only promoted the maturation of dendritic cells(DC)and the presentation of tumor specific antigens,but also induced effective immune infiltration of tumors.Overall,the integrated nanoplatform implements the concept of multiple advantages of tumor targeting,reactive drug release,and synergistic photodynamic therapy-immunotherapy,which can achieve nearly 90%tumor suppression rate in orthotopic TNBC models. | Bingchen Zhang Ling Lin Jizong Mao Weisheng Mo Zibo Li Shengtao Wang Yan Tang Chunhui Cui Yifen Wu Zhiqiang Yu | 2023 | Chinese Chemical Letters2023，34，10： | 0 |
| 20 | Experimental Study of Submergence Ratio on Local Scour Around a Square Pile in Steady Flow显示文摘Scour around a submerged square pile was realized experimentally in a steady flow to study the effects of flow depth on local scour.Flow depth to pile height ratios ranging from 1.5 to 5 in uniform sand and 2 to 5 in non-uniform sand were tested in the approaching flow velocity to critical velocity(larger than which the sediment particle is motivated)ratios of 0.56 and 1.03,respectively.The influences of flow depth were investigated on the basis of analysis of the three-dimensional topography,temporal maximum scour depth,bed profile development,and equilibrium scour depth.Results showed that the maximum scour depth was at the upstream corners of the pile other than at the stagnation point.The evolutions of the maximum scour depth data in non-uniform sand were well fitted with a recent exponential function,which characterized the initial,developing,and equilibrium stages of scour depth.The scour hole slopes upstream of the pile were found to be parallel to each other in the process of each test and were mainly governed by the sediment repose underwater.The equilibrium scour depth varied slightly with flow depth when the submergence ratio was larger than 1 in uniform sand while it was 2 in non-uniform sand.The armoring effects of coarse sediment particles markedly reduced the sediment transport in non-uniform sand despite the 0.34 increment in non-uniformity. | DU Shengtao WU Guoxiang LIANG Bingchen ZHU David Z WANG Risheng | 2023 | Journal of Ocean University of China2023，22，5： | 0 |
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