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| 1 | Genome-wide variants of Eurasian facial shape differentiation and a prospective model of DNA based face prediction显示文摘It is a long-standing question as to which genes define the characteristic facial features among different ethnic groups. In this study, we use Uyghurs, an ancient admixed population to query the genetic bases why Europeans and Han Chinese look different. Facial traits were analyzed based on high-dense 3D facial images; numerous biometric spaces were examined for divergent facial features between European and Han Chinese, ranging from inter-landmark distances to dense shape geometrics. Genome-wide association studies(GWAS) were conducted on a discovery panel of Uyghurs. Six significant loci were identified, four of which, rs1868752, rs118078182, rs60159418 at or near UBASH3B, COL23A1, PCDH7 and rs17868256 were replicated in independent cohorts of Uyghurs or Southern Han Chinese. A prospective model was also developed to predict 3D faces based on top GWAS signals and tested in hypothetic forensic scenarios. | Lu Qiao Yajun Yang Pengcheng Fu Sile Hu Hang Zhou Shouneng Peng Jingze Tan Yan Lu Haiyi Lou Dongsheng Lu Sijie Wu Jing Guo Li Jin Yaqun Guan Sijia Wang Shuhua Xu Kun Tang | 2018 | Journal of Genetics and Genomics2018，45，8： | 7 |
| 2 | Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait显示文摘Petaloid toenail,or accessory nail of the fifth toe,is a physical trait characterized by the presence of an additional tiny toenail on the small toe.Since it can occasionally cause disfigurement and tenderness while wearing tight shoes or walking,standard surgical matricectomy is often carried out to repair the petaloid toenail(Chi and Wang,2004).Chinese legends recorded petaloid | Manfei Zhang Sijie Wu Juan Zhang Yajun Yang Jingze Tan Haijuan Guan Yu Liu Kun Tang Jean Krutmann Shuhua Xu Li Jin Yaqun Guan Hui Li Sijia Wang | 2016 | Journal of Genetics and Genomics2016，43，12： | 2 |
| 3 | A genome-wide association study of facial morphology identifies novel genetic loci in Han Chinese显示文摘The human face is a heritable surface with many complex sensory organs.In recent years,many genetic loci associated with facial features have been reported in different populations,yet there is a lack of studies on the Han Chinese population.Here,we report a genome-wide association study of 3D normal human faces of 2,659 Han Chinese with autosegment phenotypes of facial morphology.We identify singlenucleotide polymorphisms(SNPs)encompassing four genomic regions showing significant associations with different facial regions,including SNPs in DENND1 B associated with the chin,SNPs among PISRT1 associated with eyes,SNPs between DCHS2 and SFRP2 associated with the nose,and SNPs in VPS13 B associated with the nose.We replicate 24 SNPs from previously reported genetic loci in different populations,whose candidate genes are DCHS2,SUPT3 H,HOXD1,SOX9,PAX3,and EDAR.These results provide a more comprehensive understanding of the genetic basis of variation in human facial morphology. | Yin Huang Dan Li Lu Qiao Yu Liu Qianqian Peng Sijie Wu Manfei Zhang Yajun Yang Jingze Tan Shuhua Xu Li Jin Sijia Wang Kun Tang Stefan Grunewald | 2021 | Journal of Genetics and Genomics2021，48，3： | 1 |
| 4 | Craniometrical evidence for population admixture between Eastern and Western Eurasians in Bronze Age southwest Xinjiang显示文摘Xinjiang,the most northwest provincial administrative area of China,was the area where the oriental people met the occidental.The populations in Xinjiang exhibit very high genetic diversity.Previous study revealed that the eastern Xinjiang populations of the Bronze Age were mixed by the Eastern and the Western Eurasians.However,few studies have been performed to reveal when the population admixture started and how far to the west it reached.In this paper,we studied 148 craniofacial traits of 18 skulls from the Bronze Age Liushui graveyard in Khotan(Keriya County) in the southwest of Xinjiang.Seventeen craniometrical parameters of the Khotan samples were then compared with those of other ancient samples from around Xinjiang using dendrogram cluster analysis,principal components analysis,and multidimensional scaling.The results indicated that population sample of Liushui graveyard was mixed by the Western and Eastern Eurasians with about 79% contribution from the east.Therefore,we demonstrated that population admixture between east and west Eurasia can be traced back to as early as 1000 BC in southwest Xinjiang. | TAN JingZe LI LiMing ZHANG JianBo FU WenQing , GUAN HaiJuan2, AO Xue2,WANG LingE1, WU XinHua3, HAN KangXin3, JIN Li1'2 & LI Hui1'2. FU WenQing GUAN HaiJuan AO Xue WANG LingE WU XinHua HAN KangXin JIN Li LI Hui | 2013 | Chinese Science Bulletin2013，58，3： | 1 |
| 5 | Two novel antimicrobial peptides from centipede venoms显示文摘 | Kanfu Peng Yi Kong Lei Zhai Xiongfei Wu Peng Jia Jingze Liu Haining Yu | 2009 | Toxicon2009，，2： | 1 |
| 6 | The research of evaluation theory foundation, method and application of financial stability显示文摘 | Wu Jingze | 2006 | Economist2006，59，4： | 1 |
| 7 | NAS4RRAM: neural network architecture search for inference on RRAM-based accelerators显示文摘The RRAM-based accelerators enable fast and energy-efficient inference for neural networks.However, there are some requirements to deploy neural networks on RRAM-based accelerators, which are not considered in existing neural networks.(1) Because the noise problem and analog-digital converters/digitalanalog converters(ADC/DAC) affect the prediction accuracy, they should be modeled in networks.(2) Because the weights are mapped to the RRAM cells, they should be quantized, and the number of weights is limited by the number of RRAM cells in the accelerator. These requirements motivate us to customize the hardware-friendly network for the RRAM-based accelerator. We take the idea of network architecture search(NAS) to design networks with high prediction accuracy that meet the requirements. We propose a framework called NAS4RRAM to search for the optimal network on the given RRAM-based accelerator. The experiments demonstrate that NAS4RRAM can apply to different RRAM-based accelerators with different scales. The performance of searched networks outperforms the manually designed ResNet. | Zhihang YUAN Jingze LIU Xingchen LI Longhao YAN Haoxiang CHEN Bingzhe WU Yuchao YANG Guangyu SUN | 2021 | Science China(Information Sciences)2021，64，6： | 0 |
| 8 | A multiphoton ionization study of acetone using time-of-flight mass spectrometry显示文摘The 3p Rydberg states of acetone and photodissociation of the acetone cation were studied using time-of-flight(TOF)mass spectrometry.The 3p Rydberg state spectroscopy of acetone was investigated with linearly polarized two-photon resonance enhanced multiphoton ionization(REMPI)from 320 to 337 nm.Several new transition bands were observed in the spectra.In addition to the CH3COCH3 + ion,CH3CO + and CH3 + fragments were observed.The laser power dependences suggest that the CH3COCH3 +,CH3CO + and CH3 + ions are produced in three-,four-,and four-photon processes,respectively.Production of CH3CO + and CH3 + involves excitation of the ground state acetone cation by an additional photon and subsequent decomposition of the excited acetone ion.The average translational energies of CH3CO + and CH3 + from dissociation in CH3COCH3 +(X)+hv→CH3CO + +CH3 and CH3COCH3 +(X)+hv→CH3 + +CH3CO,respectively,were derived from the ion TOF peak profiles. | ZHENG XianFeng WU HongXia SONG Yu WU JingZe ZHANG JingSong CUI ZhiFeng | 2010 | Chinese Science Bulletin2010，55，27： | 0 |
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