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| 1 | Conservation metagenomics: a new branch of conservation biology显示文摘Multifaceted approaches are required to monitor wildlife populations and improve conservation efforts. In the last decade,increasing evidence suggests that metagenomic analysis offers valuable perspectives and tools for identifying microbial communities and functions. It has become clear that gut microbiome plays a critical role in health, nutrition, and physiology of wildlife, including numerous endangered animals in the wild and in captivity. In this review, we first introduce the human microbiome and metagenomics, highlighting the importance of microbiome for host fitness. Then, for the first time, we propose the concept of conservation metagenomics, an emerging subdiscipline of conservation biology, which aims to understand the roles of the microbiota in evolution and conservation of endangered animals. We define what conservation metagenomics is along with current approaches, main scientific issues and significant implications in the study of host evolution, physiology,nutrition, ecology and conservation. We also discuss future research directions of conservation metagenomics. Although there is still a long way to go, conservation metagenomics has already shown a significant potential for improving the conservation and management of wildlife. | Fuwen Wei Qi Wu Yibo Hu Guangping Huang Yonggang Nie Li Yan | 2019 | Science China(Life Sciences)2019，62，2： | 10 |
| 2 | Diet drives convergent evolution of gut microbiomes in bamboo-eating species显示文摘Gut microbiota plays a critical role in host physiology and health.The coevolution between the host and its gut microbes facilitates animal adaptation to its specific ecological niche.Multiple factors such as host diet and phylogeny modulate the structure and function of gut microbiota.However,the relative contribution of each factor in shaping the structure of gut microbiota remains unclear.The giant(Ailuropoda melanoleuca)and red(Ailurus styani)pandas belong to different families of order Carnivora.They have evolved as obligate bamboo-feeders and can be used as a model system for studying the gut microbiome convergent evolution.Here,we compare the structure and function of gut microbiota of the two pandas with their carnivorous relatives using 16S rRNA and metagenome sequencing.We found that both panda species share more similarities in their gut microbiota structure with each other than each species shares with its carnivorous relatives.This indicates that the specialized herbivorous diet rather than host phylogeny is the dominant driver of gut microbiome convergence within Arctoidea.Metagenomic analysis revealed that the symbiotic gut microbiota of both pandas possesses a high level of starch and sucrose metabolism and vitamin B12 biosynthesis.These findings suggest a diet-driven convergence of gut microbiomes and provide new insight into host-microbiota coevolution of these endangered species. | Guangping Huang Xiao Wang Yibo Hu Qi Wu Yonggang Nie Jiuhong Dong Yun Ding Li Yan Fuwen Wei | 2021 | Science China(Life Sciences)2021，64，1： | 6 |
| 3 | Large-scale blow spinning of heat-resistant nanofibrous air filters显示文摘Particulate matter(PM)pollution has become a serious problem worldwide and various kinds of nanofibrous filters aiming to solve the problem have been developed.It is urgent to remove PM from high-temperature pollution sources,such as industrial emissions,coal furnaces,and automobile exhaust gases.However,filtration at pollution sources remains challenging because most existing air filters are not resistant to high temperature.Herein,heat-resistant polyimide(PI)nanofibrous air filters are fabricated via a simple and scalable solution blow-spinning method.These air filters show excellent thermal stability at high temperature up to 420℃.They exhibit a filtration efficiency as high as 99.73%at ambient temperature and over 97%at 300℃.In addition,a field test shows that the filters remove>97%of PM from the car exhaust fumes.Hence,the blow-spun PI nanofibrous membranes combined with the facile preparation strategy have great potential in high temperature air filtration fields and other similar applications such as water purification and protein separation. | Ziwei Li Jianan Song Yuanzheng Long Chao Jia Zhenglian Liu Lei Li Cheng Yang Junchen Liu Sen Lin Haiyang Wang Yibo Liu Minghao Fang Hui Wu | 2020 | Nano Research2020，13，3： | 6 |
| 4 | In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids显示文摘Unlike most organs that mature during the fetal period,the male reproductive system reaches maturity only at puberty with the commencement of spermatogenesis.Robust modelling of human testicular organogenesis in vitro would facilitate research into mechanisms of and factors affecting human spermatogenic failure and male fertility preservation in prepubertal tumor patients.Here,we report successful recapitulation of human testicular organogenesis in vitro from fetal gonadal ridge.Our model displayed the formation of mature seminiferous epithelium and self-renewing spermatogonia.Remarkably,in vitro-derived haploid spermatids have undergone meiotic recombination,and showed increased genetic diversity as indicated by genetic analysis.Moreover,these spermatids were able to fertilize oocytes and support subsequent blastocyst formation.The in vitro testicular organogenesis system described here will play an important role in elucidating the regulation of human testis development and maintaining male fertility in prepubertal cancer patients. | Yan Yuan Laihua Li Qing Cheng Feiyang Diao Qiao Zeng Xiaoyu Yang Yibo Wu Hao Zhang Mingqian Huang Junqing Chen Quan Zhou Yunfei Zhu Rong Hua Jianyu Tian Xin Wang Zuomin Zhou Jie Hao Jinjin Yu Dong Hua Jiayin Liu Xuejiang Guo Qi Zhou Jiahao Sha | 2020 | Cell Research2020，30，3： | 6 |
| 5 | Air pollution and inhalation exposure to particulate matter of different sizes in rural households using improved stoves in central China显示文摘Household air pollution is considered to be among the top environmental risks in China.To examine the performance of improved stoves for reduction of indoor particulate matter(PM) emission and exposure in rural households, individual inhalation exposure to size-resolved PM was investigated using personal portable samplers carried by residents using wood gasifier stoves or improved coal stoves in a rural county in Central China.Concentrations of PM with different sizes in stationary indoor and outdoor air were also monitored at paired sites. The stationary concentrations of size-resolved PM in indoor air were greater than those in outdoor air, especially finer particles PM0.25. The daily averaged exposure concentrations of PM0.25, PM1.0, PM2.5 and total suspended particle for all the surveyed residents were 74.4 ± 41.1, 159.3 ± 74.3, 176.7 ± 78.1 and 217.9 ± 78.1 μg/m3,respectively. Even using the improved stoves, the individual exposure to indoor PM far exceeded the air quality guideline by WHO at 25 μg/m3. Submicron particles PM1.0 were the dominant PM fraction for personal exposure and indoor and outdoor air. Personal exposure exhibited a closer correlation with indoor PM concentrations than that for outdoor concentrations. Both inhalation exposure and indoor air PM concentrations in the rural households with gasifier firewood stoves were evidently lower than the reported results using traditional firewood stoves. However, local governments in the studied rural areas should exercise caution when widely and hastily promoting gasifier firewood stoves in place of improved coal stoves, due to the higher PM levels in indoor and outdoor air and personal inhaled exposure. | Weijian Liu Guofeng Shen Yuanchen Chen Huizhong Shen Ye Huang Tongchao Li Yilong Wang Xiaofang Fu Shu Tao Wenxin Liu Yibo Huang-Fu Weihao Zhang Chunyu Xue Guangqing Liu Fuyong Wu Minghung Wong | 2018 | Journal of Environmental Sciences2018，30，1： | 4 |
| 6 | Flotillin-2 is an acrosome-related protein involved in mouse spermiogenesis显示文摘Spermatogenesis is a complex process of terminal differentiation by which mature sperms are generated,and it can be divided into three phases:mitosis,meiosis and spermiogenesis.In a previous study,we established a series of proteomic profiles for spermatogenesis to understand the regulation of male fertility and infertility.Here,we further investigated the localization and the role of flotillin-2 in spermiogenesis.Flotillin-2 expression was investigated in the testis of male CD1 mice at various developmental stages of spermatogenesis by using Western blotting,immunohistochemistry and immunofluorescence.Flotillin-2 was knocked down in vivo in three-week-old male mice using intratesticular injection of small inhibitory RNA(siRNA),and sperm abnormalities were assessed three weeks later.Flotillin-2 was expressed at high levels in male germ cells during spermatogenesis.Flotillin-2 immunoreactivity was observed in pachytene spermatocytes as a strong dot-shaped signal and in round spermatids as a sickle-shaped distribution ahead of the acrosome.Immunofluorescence confirmed flotillin-2 was localized in front of the acrosome in round spermatids,indicating that flotillin-2 was localized to the Golgi apparatus.Knockdown of flotillin-2 in vivo led to a significant increase in head sperm abnormalities isolated from the cauda epididymis,compared with control siRNA-injected testes.This study indicates that flotillin-2 is a novel Golgi-related protein involved in sperm acrosome biogenesis. | Yibo Wu Xin Chen Shuai Wang Min Jiang Bo Zheng Quan Zhou Ye Bi Zuomin Zhou Xiaoyan Huang Jiahao Sha | 2012 | The Journal of Biomedical Research2012，26，4： | 3 |
| 7 | Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis显示文摘Depression is a serious public-health issue.Recent reports have suggested higher susceptibility to viral infections in depressive patients.However,how depression affects antiviral innate immune signaling remains unknown.Here,we revealed a reduction in expression of Abelson helper integration site 1(AHI1)in the peripheral blood mononuclear cells(PBMCs)and macrophages from the patients with major depressive disorder(MDD),which leads to attenuated antiviral immune response.We found that depression-related arginine vasopressin(AVP)induces reduction of AHI1 in macrophages.Further studies demonstrated that AHI1 is a critical stabilizer of basal type-I-interferon(IFN-I)signaling.Mechanistically,AHI1 recruits OTUD1 to deubiquitinate and stabilize Tyk2,while AHI1 reduction downregulates Tyk2 and IFN-I signaling activity in macrophages from both MDD patients and depression model mice.Interestingly,we identified a clinical analgesic meptazinol that effectively stimulates AHI1 expression,thus enhancing IFN-I antiviral defense in depression model mice.Our study promotes the understanding of the signaling mechanisms of depression-mediated antiviral immune dysfunction,and reveals meptazinol as an enhancer of antiviral innate immunity in depressive patients. | Hong-Guang Zhang Bin Wang Yong Yang Xuan Liu Junjie Wang Ning Xin Shifeng Li Ying Miao Qiuyu Wu Tingting Guo Yukang Yuan Yibo Zuo Xiangjie Chen Tengfei Ren Chunsheng Dong Jun Wang Hang Ruan Miao Sun Xingshun Xu Hui Zheng | 2022 | Cell Research2022，32，10： | 3 |
| 8 | Proteomic profiling of lipid droplet-associated proteins in primary adipocytes of normal and obese mouse显示文摘在 adipocytes 的类脂化合物微滴用作动物的主要长期的精力存储仓库。正在增加类脂化合物微滴不仅仅是一个静态的中立类脂化合物存储地点,而是事实上有活力、多功能的细胞器的识别。在结构上,类脂化合物微滴由嵌入在或跳了到 phospholipid 层的 phospholipid 单层和蛋白质包围的一个中立类脂化合物核心组成。类脂化合物微滴的表面上的蛋白质对微滴结构和动力学关键。理解类脂化合物有大中央类脂化合物微滴的主要 adipocyte 的联系微滴的 proteome,从 C57BL/6 老鼠的白脂肪质的织物的类脂化合物微滴被孤立。,和由结合的液体层析双人脚踏车团 spectrometry。以前包括 73 的 193 蛋白质的一个总数 unreported 蛋白质被识别。而且,编码同位素的亲密关系标签(ICAT ) 被用来比较类脂化合物的差别在瘦的正常和高脂肪的导致食谱的肥胖的 C57BL/6 老鼠之间的联系微滴的 proteomes。23,蛋白质由 ICAT 分析确定了, 3 蛋白质是起来调整的, 4 蛋白质在从肥胖的老鼠的脂肪质的织物的类脂化合物微滴是下面调整的。重要地,类脂化合物微滴, perilipin A 和 vimentin 的二结构的蛋白质,极大地从肥胖的老鼠在脂肪质的织物的类脂化合物微滴被减少,为类脂化合物的含有的减少的蛋白质机械微滴稳定性。 | Yubo Ding Yibo Wu Rong Zeng Kan Liao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，5： | 3 |
| 9 | Differences in the Tectonic Evolution of Basins in the CentralSouthern South China Sea and their Hydrocarbon Accumulation Conditions显示文摘To reveal the causes of differences in the hydrocarbon accumulation in continental marginal basins in the centralsouthern South China Sea,we used gravity-magnetic,seismic,drilling,and outcrop data to investigate the tectonic histories of the basins and explore how these tectonic events controlled the hydrocarbon accumulation conditions in these basins.During the subduction of the Cenozoic proto-South China Sea and the expansion of the new South China Sea,the continental margin basins in the central-southern South China Sea could be classified as one of three types of epicontinental basins:southern extensional-foreland basins,western extensional-strike slip basins,and central extensional-drift basins.Because these basins have different tectonic and sedimentary histories,they also differ in their accumulated hydrocarbon resources.During the Cenozoic,the basin groups in the southern South China Sea generally progressed through three stages:faulting and subsidence from the late Eocene to the early Miocene,inversion and uplift in the middle Miocene,and subsidence since the late Miocene.Hydrocarbon source rocks with marine-continental transitional facies dominated byⅡ-Ⅲkerogen largely developed in extremely thick Miocene sedimentary series with the filling characteristics being mainly deep-water deposits in the early stage and shallow water deposits in the late stage.With well-developed sandstone and carbonate reservoirs,this stratum has a strong hydrocarbon generation potential.During the Cenozoic,the basin groups in the western South China Sea also progressed through the three developmental stages discussed previously.Hydrocarbon source rocks with lacustrine facies,marine-continental transitional facies,and terrigenous marine facies dominated byⅡ2-Ⅲkerogen largely developed in the relatively thick stratum with the filling characteristics being mainly lacustrine deposits in the early stage and marine deposits in the late stage.As a reservoir comprised of self-generated and self-stored sandstone,this unit also has a high hydrocarbon generation potential.Throughout those same three developmental stages,the basin groups in the central South China Sea generated hydrocarbon source rocks with terrigenous marine facies dominated byⅢkerogen that have developed in a stratum with medium thicknesses with the filling characteristics being mainly sandstone in the early stage and carbonate in the late stage.This reservoir,which is dominated by lower-generation and upper-storage carbonate rocks,also has a high hydrocarbon generation potential. | TANG Wu ZHAO Zhigang SONG Shuang WANG Yibo XIE Xiaojun LIU Shixiang | 2021 | Acta Geologica Sinica(English Edition)2021，95，1： | 3 |
| 10 | Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats显示文摘Cell-based transplantation strategies possess great potential for spinal cord injury(SCI)repair.Basic fibroblast growth factor(bFGF)has been reported to have multiple neuro-promoting effects on developing and adult nervous system of mammals and considered a promising therapy for nerve injury following SCI.Human dental pulp stem cells(DPSCs)are abundant stem cells with low immune rejection,which can be considered for cell replacement therapy.The purpose of this study was to investigate the roles of DPSCs which express bFGF under the regulation of five hypoxia-responsive elements(5HRE)using an adeno-associated virus(AAV-5HRE-bFGF-DPSCs)in SCI repairing model.In this study,DPSCs were revealed to differentiate into CD13^(+)pericytes and up-regulate N-cadherin expression to promote the re-attachment of CD13^(+)pericytes to vascular endothelial cells.The re-attachment of CD13^(+)pericytes to vascular endothelial cells subsequently increased the flow rate of blood in microvessels via the contraction of protuberance.As a result,increased numbers of red blood cells carried more oxygen to the damaged area and the local hypoxia microenvironment in SCI was improved.Thus,this study represents a step forward towards the potential use of AAV-5HRE-bFGF-DPSCs in SCI treatment in clinic. | Sipin Zhu Yibo Ying Yan He Xingxing Zhong Jiahui Ye Zhiyang Huang Min Chen Qiuji Wu Yifan Zhang Ziyue Xiang Yurong Tu Weiyang Ying Jian Xiao Xiaokun Li Qingsong Ye Zhouguang Wang | 2021 | Bioactive Materials2021，6，8： | 2 |
| 11 | Diffuse Intrinsic Pontine Gliomas Exhibit Cell Biological and Molecular Signatures of Fetal Hindbrain-Derived Neural Progenitor Cells显示文摘Diffuse intrinsic pontine glioma(DIPG) is the main cause of brain tumor-related death among children.Until now, there is still a lack of effective therapy with prolonged overall survival for this disease. A typical strategy for preclinical cancer research is to find out the molecular differences between tumor tissue and para-tumor normal tissue, in order to identify potential therapeutic targets. Unfortunately, it is impossible to obtain normal tissue for DIPG because of the vital functions of the pons.Here we report the human fetal hindbrain-derived neural progenitor cells(pontine progenitor cells, PPCs) as normal control cells for DIPG. The PPCs not only harbored similar cell biological and molecular signatures as DIPG glioma stem cells, but also had the potential to be immortalized by the DIPG-specific mutation H3 K27 M in vitro. These findings provide researchers with a candidate normal control and a potential medicine carrier for preclinical research on DIPG. | Yu Sun Cheng Xu Changcun Pan Xin Chen Yibo Geng Yuliang Wu Peng Zhang Wenhao Wu Yu Wang Deling Li Zhen Wu Junting Zhang Qiaoran Xi Liwei Zhang | 2019 | Neuroscience Bulletin2019，35，2： | 2 |
| 12 | A shear-thinning,ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis显示文摘Spinal cord injury(SCI)is a serious clinical disease.Due to the deformability and fragility of the spinal cord,overly rigid hydrogels cannot be used to treat SCI.Hence,we used TPA and Laponite to develop a hydrogel with shear-thinning ability.This hydrogel exhibits good deformation,allowing it to match the physical properties of the spinal cord;additionally,this hydrogel scavenges ROS well,allowing it to inhibit the lipid peroxidation caused by ferroptosis.According to the in vivo studies,the TPA@Laponite hydrogel could synergistically inhibit ferroptosis by improving vascular function and regulating iron metabolism.In addition,dental pulp stem cells(DPSCs)were introduced into the TPA@Laponite hydrogel to regulate the ratios of excitatory and inhibitory synapses.It was shown that this combination biomaterial effectively reduced muscle spasms and promoted recovery from SCI. | Yibo Ying Zhiyang Huang Yurong Tu Qiuji Wu Zhaoyu Li Yifan Zhang Huilei Yu Annian Zeng Hanzhi Huang Jiahui Ye Weiyang Ying Min Chen Zhiyi Feng Ziyue Xiang Qingsong Ye Sipin Zhu Zhouguang Wang | 2023 | Bioactive Materials2023，，4： | 2 |
| 13 | Interpretable machine-learning strategy for soft-magnetic property and thermal stability in Fe-based metallic glasses显示文摘Fe-based metallic glasses(MGs)have been extensively investigated due to their unique properties,especially the outstanding soft-magnetic properties.However,conventional design of soft-magnetic Fe-based MGs is heavily relied on“trial and error”experiments,and thus difficult to balance the saturation flux density(Bs)and thermal stability due to the strong interplay between the glass formation and magnetic interaction.Herein,we report an eXtreme Gradient Boosting(XGBoost)machine-learning(ML)model for developing advanced Fe-based MGs with a decent combination of Bs and thermal stability. | Zhichao Lu Xin Chen Xiongjun Liu Deye Lin Yuan Wu Yibo Zhang Hui Wang Suihe Jiang Hongxiang Li Xianzhen Wang Zhaoping Lu | 2020 | npj Computational Materials2020，，1： | 2 |
| 14 | Ultrathin salt-free polymer-in-ceramic electrolyte for solid-state sodium batteries显示文摘The practical energy density of solid-state batteries remains limited,partly because of the lack of a general method to fabricate thin membranes for solid-state electrolytes with high ionic conductivity and low area-specific resistance(ASR).Herein,we use an ultrahigh concentration of a ceramic ion conductor(Na_(3)SbS_(4))to build an ionconduction“highway”,and a polymer(polyethylene oxide,2 wt%)as a flexible host to prepare a polymer-inceramic ion-conducting membrane of approximately 40μm.Without the use of any salt(e.g.,NaPF_(6)),the resulting membrane exhibits a threefold increase in electronic ASR and a twofold decrease in ionic ASR compared with a pure ceramic counterpart.The activation energy for sodium-ion transport is only 190 meV in the membrane,similar to that in pure ceramic,suggesting ion transport predominantly occurs through a percolated network of ion-conducting ceramic particles.The salt-free design also provides an opportunity to suppress dendritic metal electrodeposits,according to a recently refined chemomechanical model of metal deposition.Our work suggests that salt is not always necessary in composite solid-state electrolytes,which broadens the choice of polymers to allow the optimization of other desired attributes,such as mechanical strength,chemical/electrochemical stability,and cost. | Bin Tang Yibo Zhao Zhiyi Wang Shiwei Chen Yifan Wu Yuming Tseng Lujiang Li Yunlong Guo Zhen Zhou Shou-Hang Bo | 2021 | eScience2021，1，2： | 2 |
| 15 | Versatile subtypes of pericytes and their roles in spinal cord injury repair,bone development and repair显示文摘Vascular regeneration is a challenging topic in tissue repair. As one of the important components of the neurovascular unit(NVU),pericytes play an essential role in the maintenance of the vascular network of the spinal cord. To date, subtypes of pericytes have been identified by various markers, namely the PDGFR-β, Desmin, CD146, and NG2, each of which is involved with spinal cord injury(SCI) repair. In addition, pericytes may act as a stem cell source that is important for bone development and regeneration, whilst specific subtypes of pericyte could facilitate bone fracture and defect repair. One of the major challenges of pericyte biology is to determine the specific markers that would clearly distinguish the different subtypes of pericytes, and to develop efficient approaches to isolate and propagate pericytes. In this review, we discuss the biology and roles of pericytes, their markers for identification, and cell differentiation capacity with a focus on the potential application in the treatment of SCI and bone diseases in orthopedics. | Sipin Zhu Min Chen Yibo Ying Qiuji Wu Zhiyang Huang Wenfei Ni Xiangyang Wang Huazi Xu Samuel Bennett Jian Xiao Jiake Xu | 2022 | Bone Research2022，10，2： | 2 |
| 16 | Revealing the effect of anion-tuning in bimetallic chalcogenides on electrocatalytic overall water splitting显示文摘Enhancing electrocatalytic water splitting performance by modulating the intrinsic electronic structure is of great importance. Here, porous bimetallic oxide and chalcogenide nanosheets grown on carbon paper denoted as NiCo2X4/CP (X = O, S, and Se) are prepared to demonstrate how the anion components affect the electronic structures and thereby disclose the correlation between their intermediates interaction and catalytic activities. The experimental characterization and theoretical calculation demonstrate that Se and S substitution can promote the ratio of Co^(3+)/Co^(2+) and thereby modulate the electronic structure accompanied with the upshift of d band centers, which not only enhance the inner conductivity but also regulate the interaction between the catalyst surface and intermediates, especially for the adsorption of absorbed H and hydroperoxy intermediates towards respective hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). As a result, a full alkaline electrolyzer using NiCo2Se4/CP and NiCo2S4/CP as cathode and anode delivers a low voltage of 1.51 V at 10 mA·cm^(−2), which is comparable even superior to most transition metal-based electrolyzers. | Jian Zhou Yibo Dou Tao He Awu Zhou Xiang-Jing Kong Xue-Qian Wu Tongxin Liu Jian-Rong Li | 2021 | Nano Research2021，14，12： | 2 |
| 17 | Effects of exposure to 1.8 GHz radiofrequency field on the expression of Hsps and phosphorylation of MAPKs in human lens epithelial cells显示文摘 | Yibo Yu Ke Yao Wei Wu Kaijun Wang Guangdi Chen Deqiang Lu | 2008 | Cell Research2008，18，12： | 2 |
| 18 | Stable Ni-rich layered oxide cathode for sulfide-based all-solid-state lithium battery显示文摘Sulfide-based all-solid-state lithium-ion batteries(ASSLIBs)are one of the most promising energy storage technologies due to their high safety and ionic conductivity.To achieve greater energy density,a Ni-rich layered oxide LiNi_(x)Co_(y)M_(1-x-y)O_(2)(NCM,MMn/Al,x≥0.6)is desirable due to its relatively high voltage and large capacity.However,interfacial side reactions between the NCM and sulfide solid electrolytes lead to undesirable interfacial passivation layers and low ionic conductivity,thereby degrading the electrochemical performance of NCM sulfide all-solid-state batteries.Herein,a time-/cost-effective sulfidation strategy is exploited to sulfidize a Ni-rich NCM_(88) cathode in a mixed gas atmosphere of N_(2) and CS_(2).A new type of cathode(NCM88-S)with an ultrathin(∼2nm)surface layer is obtained,which significantly reduces the interfacial side reactions/resistance and improves the interfacial stability.The resulting NCM_(88)-S/Li_(6)PS_(5)Cl/Li_(4)Ti_(5)O_(12) ASSLIB exhibits superior performance,including a high discharge specific capacity(200.7 mAh g−1)close to that of liquid batteries,excellent cycling performance(a capacity retention of 87%after 500 cycles),and satisfactory rate performance(158.3 mAh g^(−1) at 1C). | Yue Wang Zhixuan Wang Dengxu Wu Quanhai Niu Pushun Lu Tenghuan Ma Yibo Su Liquan Chen Hong Li Fan Wu | 2022 | eScience2022，2，5： | 2 |
| 19 | The expression and localization of a novel protein phosphatase inhibitor 2810408A11Rik in mouse testis and sperm显示文摘This study investigated the expression and distribution of 2810408A11Rik in mouse testis and sperm,and explored its role in spermatogenesis and sperm function.The expression levels of 2810408A11Rik mRNA in multiple tissue samples were analyzed using bioinformatic resources and RT-PCR technique.A specific rabbit polyclonal antibody was prepared by prokaryotic expression of 2810408A11Rik recombinant protein and utilized for animal immunization.Western blotting,immunohistochemistry and immunofluorescence were used to detect the expression and distribution of 2810408A11Rik.The results of the bioinformatic analysis and RT-PCR showed that 2810408A11Rik mRNA was specifically expressed in mouse testis,and 2810408A11Rik protein included a protein phosphatase inhibitor domain.Western blotting assays,immunohistochemistry and immunofluorescence confirmed the expression of 2810408A11Rik protein in mouse testis,especially in post-meiosis round and long spermatids,and that it is localized in the acrosome and the post-nucleus area of sperm.Our findings suggest that 2810408A11Rik may play an important role in spermatogenesis,sperm capacitation and fertilization. | Ye Bi Mingxi Liu Wenjiao Tu Yibo Wu Xuejiang Guo Zuomin Zhou Jiahao Sha | 2012 | The Journal of Biomedical Research2012，26，2： | 1 |
| 20 | Design of parallel bear- ing structure for 800MN forging press with consideration of manufac- turing errors显示文摘 | Li Yibo Wu Daohui Huang Minghui | 2011 | Applied Mechanics and Materals2011，，5254： | 1 |
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