|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 2 | The novel amyloid-beta peptide aptamer inhibits intracellular amyloid-beta peptide toxicity显示文摘Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredoxin (TRX) using molecular cloning technique to construct a fusion gene that can express the TRX1-ABAD-DP-TRX2 aptamer. Moreover, adeno-associated virus was used to allow its stable expression. Immunofluorescent staining revealed the co-expression of the transduced fusion gene TRX1-ABAD-DP-TRX2 and amyloid β peptide in NIH-3T3 cells, indicating that the TRX1-ABAD-DP-TRX2 aptamer can bind amyloid β peptide within cells. In addition, cell morphology and MTT results suggested that TRX1-ABAD-DP-TRX2 attenuated amyloid β peptide-induced SH-SY5Y cell injury and improved cell viability. These findings confirmed the possibility of constructing TRX-based peptide aptamer using ABAD-DP. Moreover, TRX1-ABAD-DP-TRX2 inhibited the cytotoxic effect of amyloid β peptide. | Xu Wang Yi Yang Mingyue Jia Chi Ma Mingyu Wang Lihe Che Yu Yang Jiang Wu | 2013 | Neural Regeneration Research2013，8，1： | 2 |
| 3 | Perihepatic nodes detected by point-of-care ultrasound in acute hepatitis and acute-on-chronic liver disease显示文摘AIM: To study the manifestations of perihepatic lymph nodes during the episode of acute hepatitis flare by point-of-care ultrasonography.METHODS: One hundred and seventy-six patients with an episode of acute hepatitis flare(ALT value > 5 × upper normal limit) were enrolled retrospectively. Diagnosis of etiology of the acute hepatitis flare was based on chart records and serological and virological assays. The patients were categorized into two groups(viral origin and non-viral origin) and further defined into ten subgroups according to the etiologies. An ultrasonograpy was performed within 2 h to 72 h(median, 8 h). The maximum size of each noticeable lymph node was measured. Correlation between clinical parameters and nodal manifestations was analyzed RESULTS: Enlarged lymph nodes(width ≥ 5mm)were noticeable in 110(62.5%) patients, mostly in acute on chronic hepatitis B(54.5%). The viral group had a higher prevalence rate(89/110 = 80.9%) and larger nodal size(median, 7 mm) than those of the non-viral group(21/66 = 31.8%; median, 0 mm)(P < 0.001 for both). Meanwhile, there were significant differences in the nodal size between acute and chronic viral groups(P < 0.01), and between acute hepatitis A and non-hepatitis A viral groups(P < 0.001). In logistical regression analysis, the nodal width still showed strong significance in multivariate analysis(P < 0.0001) to stratify the two groups. The area under the curve of ROC was 0.805, with a sensitivity of 80.9%, a specificity of 68.2%, positive predictive value of 80.92%, negative predictive value of 68.18%, and an accuracy of 76.14%. CONCLUSION: Point-of-care ultrasonography to detect perihepatic nodal change is valuable for clarifying the etiologies in an episode of acute hepatitis flare. | I Che Feng Szu Jen Wang Ming Jen Sheu Lok-Beng Koay Ching Yih Lin Chung Han Ho Chi Shu Sun Hsing Tao Kuo | 2015 | World Journal of Gastroenterology2015，21，44： | 2 |
| 4 | Involvement of lbeA in meningitic Escherichia coli Kl-induced polymorphonuclear leukocyte transmigration across brain endothelial cells显示文摘 | Che X Chi F Wang L | 2011 | Brain Pathol2011，21，4： | 1 |
| 5 | Involvement of IbeA in meningitic Escherichia coli K1-induced polymorphonuclear leukocyte transmigration across brain endothelial cells显示文摘 | Che X Chi F Wang L | | 0，，04： | 1 |
| 6 | The Composition of Chinese Edible Birds’Nests and the Nature of their Proteins显示文摘 | Chi Che Wang | 1921 | Journal of Biological Chemistry1921，，2： | 1 |
| 7 | The Isolation and the Nature of the Amino Sugar of Chinese Edible Birds’Nests显示文摘 | Chi Che Wang | 1921 | Journal of Biological Chemistry1921，，2： | 1 |
| 8 | Intra‐operative management of low portal vein flow in pediatric living donor liver transplantation显示文摘 | Ting‐Lung Lin Li‐Wei Chiang Chao‐Long Chen Shih‐Hor Wang Chih‐Che Lin Yueh‐Wei Liu Chee‐Chien Yong Tsan‐Shiun Lin Wei‐Feng Li Bruno Jawan Yu‐Fan Cheng Tai‐Yi Chen Allan M. Concejero Chih‐Chi Wang | 2012 | Transplant International2012，，5： | 1 |
| 9 | A study of weldability and fracture modes in electron beam weldments of AZ series magnesium alloys显示文摘 | Chi Chao Ting Chao Chuen Guang Liu Tzeng Feng Wang Che Chung | 2006 | Materials Science and Engineering A2006，，67： | 1 |
| 10 | Outcomes of long storage times for cryopreserved vascular grafts in outflow reconstruction in living donor liver transplantation显示文摘 | Chih‐Chi Wang Salvador Lopez‐Valdes Ting‐Lung Lin Anthony Yap Chee‐Chien Yong Wei‐Feng Li Shih‐Ho Wang Chih‐Che Lin Yueh‐Wei Liu Tsan‐Shiun Lin Allan M. Concejero Hock‐Liew Eng Douglas Henry Yu‐Fan Cheng Bruno Jawan Chao‐Long Chen | 2014 | Liver Transpl2014，，2： | 1 |
| 11 | Calcium and Phosphorus Determinations in the Blood Plasma in Rickets and Tetany 显示文摘 | Hess J H Calvin J K Wang Chi Che Felcher A | 1923 | American Journal of Diseases of Children1923，26，3： | 1 |
| 12 | Involvement of TheA in meningitic Escherichia coli KI-induced polymorphonuclear leukocyte transmigrationacross brain endothelial cells 显示文摘 | Che X Chi F Wang L | 2011 | Brain Pathol2011，21，38： | 1 |
| 13 | Research progress on intervention of traditional Chinese medicine on myocardial glucose and lipid metabolism in heart failure显示文摘Disorder of energy metabolism is a major pathological change in the progression of heart failure.This process leads to insufficient myocardial energy and further aggravates cardiac dysfunction.Disorders of metabolic substrate utilization,mainly glucose and fatty acids,play an important role in this process.Research over the years has shown that some traditional Chinese medicines or compound prescriptions whose main role is to replenish qi and warm yang have good effects in regulating energy metabolism disorders.It has been found that some active ingredients in traditional Chinese medicine can regulate the uptake and utilization of myocardial cell metabolic substrate,so that the metabolism of myocardial cells can be adjusted in a direction that is beneficial to the body under hypoxic conditions,increasing the overall energy supply of the myocardium and improving heart function.This article reviewed the research of traditional Chinese medicine intervention on glucose and lipid metabolism of heart failure myocardial cells,and preliminarily summarizes the law and mechanism of traditional Chinese medicine intervention in heart failure myocardial glucose and fatty acid metabolism,hoping to provide clues for energy metabolism therapy research from the perspective of traditional Chinese medicine. | WANG Xiao-lin CHE Chi CHEN Zhi-yong HUANG Wan-qing WANG Xing LINGLi LIU Zhi-ming LI Lin | 2022 | Journal of Hainan Medical University2022，28，16： | 0 |
| 14 | A nanonewton-scale biomimetic mechanosensor显示文摘Biomimetic mechanosensors have profound implications for various areas,including health care,prosthetics,human‒machine interfaces,and robotics.As one of the most important parameters,the sensitivity of mechanosensors is intrinsically determined by the detection resolution to mechanical force.In this manuscript,we expand the force detection resolution of current biomimetic mechanosensors from the micronewton to nanonewton scale.We develop a nanocrack-based electronic whisker-type mechanosensor that has a detection resolution of 72.2 nN.We achieve the perception of subtle mechanical stimuli,such as tiny objects and airflow,and the recognition of surface morphology down to a 30 nm height,which is the finest resolution ever reported in biomimetic mechanosensors.More importantly,we explore the use of this mechanosensor in wearable devices for sensing gravity field orientation with respect to the body,which has not been previously achieved by these types of sensors.We develop a wearable smart system for sensing the body’s posture and movements,which can be used for remote monitoring of falls in elderly people.In summary,the proposed device offers great advantages for not only improving sensing ability but also expanding functions and thus can be used in many fields not currently served by mechanosensors. | Chi Zhang Mengxi Wu Ming Li Lixuan Che Zhiguang Tan Di Guo Zhan Kang Shuye Cao Siqi Zhang Yu Sui Jining Sun Liding Wang Junshan Liu | 2023 | Microsystems & Nanoengineering2023，9，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员