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| 1 | Structure and deformation around the Gyirong basin, north Himalaya, and onset of the south Tibetan detachment system显示文摘Gyirong basin and its adjacent area are located at a special position in the Himalayan orogen, where the south Tibetan detachment system (STDS) and N-S trending rift converged. The north Himalayan orogen here can be divided into five petrologic-tectonic units successively from south to north: 1) the Greater Himalayan crystalline complex (GHC); 2) the STDS shear zone; 3) the Tethyan Himalayan sedimentary sequence (THS); 4) the late Cenozoic sedimentary basins, such as Gyirong and Oma basins; and 5) the Malashan gneiss dome. Structural studies show that this area experienced four stages of deformation: 1) the earlier south-directed thrusting, preserved both in the GHC and THS; 2) top-down-to-north slip along the STDS, normal faults related to this slip formed the early controlling structures of the Cenozoic basins,and the tilted pattern of the blocks between the basins indicated a north-directed slip; 3) east-west extension, the resultant N-S trending normal fault formed the eastern boundary of the basins; and 4) late gravitational collapse. Zircon SHRIMP U-Pb dating on the syn-deformational (leuco-) granite along the STDS indicates that the major activity of the STDS occurred at ca. 26 Ma, but its onset may have begun as early as ca. 36 Ma. | YANG XiongYing ZHANG JinJiang QI GuoWei WANG DeChao GUO Lei LI PengYuan LIU Jiang | 2009 | Science China Earth Sciences2009，52，8： | 33 |
| 2 | Surface Flood and Underground Flood in Xiangxi River Karst Basin: Characteristics, Models, and Comparisons显示文摘Xiangxi River Basin, located in western Hubei Province in central China, is a karst ridge-trough area with an inhomogeneous and complicated distribution of water resources. This paper compares the characteristics of surface and subsurface floods in this karst basin, utilizing a one-parameter Darcian model and the traditional exponential model. The observed hydrographs and inferred water components are strikingly similar for surface and subsurface floods. The Darcian model and the exponential model are based on different views of the flood generation process, with the former fitting the entire hydrograph with a single time constant, and the latter fitting only the recession limb with multiple time constants. Due to the anisotropy and heterogeneity of karst media, a combination of physical and chemical techniques including the use of 3S(remote sensing, geographical information system, global positioning system) method is proposed for an enhanced hydrological investigation to assess and characterize karst water resources in mountainous areas. | Mingming Luo Zhihua Chen Dechao Yin Hamza Jakada He Huang Hong Zhou Tao Wang | 2016 | Journal of Earth Science2016，27，1： | 4 |
| 3 | Recent progress of flexible sulfur cathode based on carbon host for lithium-sulfur batteries显示文摘With the emergence and development of wearable devices,the novel ene rgy storage systems with flexible feature and high energy density are urgently needed.As we all know,for next generation high energystorage systems,lithium-sulfur(Li-S) batteries with a high theoretical capacity are regarded as one of the most promising candidates.In addition,the flexible Li-S batteries have received more and more attention.The determined factor in the flexible Li-S batteries is how to design the foldable electrodes including both anode and cathode.As for the flexible sulfur cathode,it could be obtained by integrating the electroactive sulfur with a flexible substrate,generally.In recent years,the flexible cathode of Li-S batteries have made considerable progress,however there are also many huge challenges needing to overcome,such as low content of sulfur,fast decrease of capacity and short cycle life.In this paper,the current develop status of flexible cathodes of Li-S batteries have been summarized,and the future trend also be pointed out. | Zhuosen Wang Xijun Xu Shaomin Ji Zhengbo Liu Dechao Zhang Jiadong Shen Jun Liu | 2020 | Journal of Materials Science & Technology2020，52，20： | 3 |
| 4 | A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity显示文摘Tumor escape from immune-mediated destruction has been associated with immunosuppressive mechanisms that inhibit T-cell activation.A promising strategy for cancer immunotherapy is to disrupt key pathways regulating immune tolerance,such as program death-1(PD-1/PD-L1)pathway in the tumor environment.However,the determinants of response to anti-PD-1 monoclonal antibodies(mAbs)treatment remain incompletely understood.In murine models,PD-1 blockade alone fails to induce effective immune responses to poorly immunogenic tumors,but is successful when combined with additional interventions,such as cancer vaccines.Novel cancer vaccines combined with antibody may offer promising control of cancer development and progression.In this investigation,we generated a novel tumor cell vaccine simultaneously expressing anti-PD-1 mAbs and granulocyte-macrophage colony stimulating factor(GM-CSF)in CT26 colon cancer and B16-F10 melanoma.The antitumor effect of the vaccine was verified by therapeutic and adoptive animal experiments in vivo.The antitumor mechanism was analyzed using Flow cytometry,Elispot and in vivo intervention approaches.The results showed that tumor cell vaccine secreting PD-1 neutralizing antibodies and GM-CSF induced remarkable antitumor immune effects and prolonged the survival of tumor-bearing animals compared with animals treated with either PD-1 mAbs or GM-CSF alone.Antitumor effects and prolonged survival correlated with strong antigen-specific T-cell responses by analyzing CD11c^(+)CD86^(+)DC,CD11b^(+)F4/80^(+)MΦcells,increased ratio of Teff/Treg in the tumor microenvironment,and higher secretion levels of Th1 proinflammatory cytokines in serum.Furthermore,the results of ELISPOT and in vivo blocking strategies further confirmed that the antitumor immune response is acquired by CD4 and CD8 T immune responses,primarily dependent on CD4 Th1 immune response,not NK innate immune response.The combination of PD-1 blockade with GM-CSF secretion potency creates a novel tumor cell vaccine immunotherapy,affording significantly improved antitumor responses by releasing the state of immunosuppressive microenvironment and augmenting the tumor-reactive T-cell responses. | Hongwei Tian Gang Shi Qin Wang Yiming Li Qianmei Yang Chunlei Li Guoyou Yang Min Wu Qian Xie Shuang Zhang Yang Yang Rong Xiang Dechao Yu Yuquan Wei Hongxin Deng | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 3 |
| 5 | Factors influencing the effectiveness of online group buying in the restaurant industry显示文摘 | Ziqiong Zhang Zili Zhang Fan Wang Rob Law Dechao Li | 2013 | International Journal of Hospitality Management2013，，： | 2 |
| 6 | Surgical Treatment and Prognosis of Synchronous Double Primary Lung Cancer: a Report of 31 Cases显示文摘 | Feiyue Feng Dechao Zhang Xiangyang Liu Yonggang Wang Yousheng Mao | 2005 | Chinese Journal of Clinical Oncology2005，2，5： | 1 |
| 7 | Rapid identification of spinal ventral and dorsal roots using a quartz crystal microbalance显示文摘The fast and accurate identification of nerve tracts is critical for successful nerve anastomosis.Taking advantage of differences in acetylcholinesterase content between the spinal ventral and dorsal roots,we developed a novel quartz crystal microbalance method to distinguish between these nerves based on acetylcholinesterase antibody reactivity.The acetylcholinesterase antibody was immobilized on the electrode surface of a quartz crystal microbalance and reacted with the acetylcholinesterase in sample solution.The formed antigen and antibody complexes added to the mass of the electrode inducing a change in frequency of the electrode.The spinal ventral and dorsal roots were distinguished by the change in frequency.The ventral and dorsal roots were cut into 1 to 2-mm long segments and then soaked in 250 μL PBS.Acetylcholinesterase antibody was immobilized on the quartz crystal microbalance gold electrode surface.The results revealed that in 10 minutes,both spinal ventral and dorsal roots induced a frequency change;however,the frequency change induced by the ventral roots was notably higher than that induced by the dorsal roots.No change was induced by bovine serum albumin or PBS.These results clearly demonstrate that a quartz crystal microbalance sensor can be used as a rapid,highly sensitive and accurate detection tool for the quick identification of spinal nerve roots intraoperatively. | Tao Sui Jun Que Dechao Kong Hao Xie Daode Wang Kun Shi Xiaojian Cao Xiang Li | 2013 | Neural Regeneration Research2013，8，8： | 1 |
| 8 | AndyApplication of Artificial Neural Networks for Decision Support in Medicine显示文摘 | Larder Brendan Wang Dechao Revell | 2008 | Methods in Molecular Biology2008，，： | 1 |
| 9 | A generalizable strategy based on the rule of“like dissolves like”to construct porous liquids with low viscosity for CO_(2)capture显示文摘Porous liquids(PLs),an emerging porous material with permanent cavities,have attracted extensive attention in recent years.However,the current construction methods are complicated and resulting PLs possess high viscosity values,which cannot meet the requirements of practical industrial applications.Herein,we demonstrate a generalizable and simple strategy to prepare type III PLs with low viscosity based on the rule of“like dissolves like”.Specifically,the monoglycidyl ether terminated polydimethylsiloxane(denoted by E-PDMS)is attached to the surface of Universitetet i Oslo(UiO)-66-NH_(2)via covalent linkage,constructing the pore generator(UiO-66-NH_(2)-E-PDMS,denoted by P-UiO-66).Then,P-UiO-66 is dispersed into different types and amounts of sterically hindered solvents(PDMS400 or PDMS6000),obtaining a series of type III PLs(denoted by P-UiO-66-PLs)with permanent cavities and low viscosities.The gas sorption-desorption test shows that P-UiO-66-PLs have an enormous potential for CO_(2)/N_(2) selective separation.Besides,the porosity of P-UiO-66-PLs and the CO_(2)sorption mechanism are demonstrated by molecular simulation.Furthermore,the generality of the synthesis strategy is confirmed by the successful construction of PLs using two other amino-metal-organic frameworks(MOFs)(MIL-53(Al)-NH_(2)and MIL-88B(Fe)-NH_(2)).Importantly,it’s worth noting that the strategy based on the rule of“like dissolves like”sheds light on the preparation of other types of PLs for task-specific applications. | Yangyang Xin Hailong Ning Dechao Wang(✉) Xiaoqian Li Wendi Fan Xiaoqian Ju Hongni Wang Yichi Zhang Zhiyuan Yang Dongdong Yao Yaping Zheng | 2023 | Nano Research2023，16，7： | 1 |
| 10 | Interface engineering for composite cathodes in sulfide-based all-solid-state lithium batteries显示文摘All-solid-state lithium battery(ASLB)based on sulfide-based electrolyte is considered to be a candidate for the next-generation high-energy storage system.Despite the high ionic conductivity of sulfide solid electrolyte,the poor interfacial stability(mechanically and chemically)between active materials and sulfide solid electrolytes in composite cathodes leads to inferior electrochemical performances,which impedes the practical application of sulfide electrolytes.In the past years,various of strategies have been carried out to achieve an interface with low impedance in the composite cathodes.Herein,a review of recent progress of composite cathodes for all-solid-state sulfide-based lithium batteries is summarized,including the interfacial issues,design strategies,fabrication methods,and characterization techniques.Finally,the main challenges and perspectives of composite cathodes for high-performance all-solidstate batteries are highlighted for future development. | Yu Li Dechao Zhang Xijun Xu Zhuosen Wang Zhengbo Liu Jiadong Shen Jun Liu Min Zhu | 2021 | Journal of Energy Chemistry2021，30，9： | 1 |
| 11 | Chemically derived graphene quantum dots for high-strain sensing显示文摘Graphene quantum dots(GQDs)refer to graphene fragments with a lateral dimension typically less than 100 nm,which possess unique electrical and optical properties due to the quantum confinement effect.In this study,we demonstrate that chemically derived graphene quantum dots show great potential for making highly stretchable and cost-effective strain sensors via an electron tunneling mechanism.Stretch-able strain sensors are critical devices for the field of flexible or wearable electronics which are expected to maintain function up to high strain values(>30%).However,strain sensors based on conventional materials(i.e.metal or semiconductors)or metal nanoparticles(e.g.gold or silver nanoparticles)only work within a small range of strain(i.e.the former have a working range<1%and the latter<3%).In this study,by simply dropcasting solution-processed GQDs between the interdigitated electrodes on polydimethylsiloxane,we obtained devices that can function in the range from 0.06%to over 50%ten-sile strain with both the sensitivity and working range conveniently adjustable by the concentration of GQDs applied.This study provides a new concept for practical applications of GQDs,revealing the poten-tial of this material for smart applications such as artificial skin,human-machine interfaces,and health monitoring. | Shujun Wang Francesco Lenzini Dechao Chen Philip Tanner Jisheng Han David Thiel Mirko Lobino Qin Li | 2023 | Journal of Materials Science & Technology2023，，10： | 1 |
| 12 | Focal ablation therapy presents promising results for selectively localized prostate cancer patients显示文摘Due to its lower risk of consequences when compared to a radical approach, focal treatment is a viable and minimally invasive option for treating specific localized prostate cancer. Although several recent good nonrandomized trials have suggested that focused therapy may be an alternative choice for some patients, additional high-quality evidence is needed before it can be made widely available as a conventional treatment. As a result, we have summarized the most recent findings from the 38th Annual European Association of Urology Congress, one of the most renowned annual conferences in the area of urology, regarding focal ablation therapy for patients with localized prostate cancer. Additionally, we also provided clinical trials in progress for researchers to better understand the current research status of this field. | Dechao Feng Dengxiong Li Yuhan Xiao Ruicheng Wu Jie Wang Chi Zhang | 2023 | Chinese Journal of Cancer Research2023，35，4： | 0 |
| 13 | Homogenous metallic deposition regulated by abundant lithiophilic sites in nickel/cobalt oxides nanoneedle arrays for lithium metal batteries显示文摘Although lithium(Li)metal delivers the highest theoretical capacity as a battery anode,its high reactivity can generate Li dendrites and'dead'Li during cycling,resulting in poor reversibility and low Li utilization.Inducing uniform Li plating/stripping is the core of solving these problems.Herein,we design a highly lithiophilic carbon film with an outer sheath of the nanoneedle arrays to induce homogeneous Li plating/stripping.The excellent conductivity and 3D framework of the carbon film not only offer fast charge transport across the entire electrode but also mitigate the volume change of Li metal during cycling.The abundant lithiophilic sites ensure stable Li plating/stripping,thereby inhibiting the Li dendritic growth and'dead'Li formation.The resulting composite anode allows for stable Li stripping/plating under 0.5 mA cm^(-2) with a capacity of 0.5 mA h cm^(-2) for 4000 h and 3 mA cm^(-2) with a capacity of3 mA h cm^(-2) for 1000 h.The Ex-SEM analysis reveals that lithiophilic property is different at the bottom,top,or channel in the structu re,which can regulate a bottom-up uniform Li deposition behavior.Full cells paired with LFP show a stable capacity of 155 mA h g^(-1) under a current density of 0.5C.The pouch cell can keep powering light-emitting diode even under 180°bending,suggesting its good flexibility and great practical applications. | Fenqiang Luo Dawei Xu Yongchao Liao Minghao Chen Shuirong Li Dechao Wang Zhifeng Zheng | 2023 | Journal of Energy Chemistry2023，，2： | 0 |
| 14 | Occurrence and Diversity of Candida Genus in Marine Environments显示文摘A total of 317 yeast isolates from seawater,sediments,mud of salterns,guts of marine fishes and marine algae were obtained. The results of routine identification and molecular characterization showed that six isolates among these marine yeasts belonged to Candida genus as Candida intermedia for YA01a,Candida parapsilosis for 3eA2,Candida quercitrusa for JHSb,Can-dia rugosa for wl8,Candida zeylanoides for TJY13a,and Candida membranifaciens for W14-3. Isolates YA01a (Candida interme-dia),wl8 (Candida rugosa),3eA2 (Candida parapsilosis),and JHSb (Candida quercitrusa) were found producing cell-bound lipase,while isolate W14-3 (Candida membranifaciens) producing riboflavin. These marine yeast Candida spp. seem to have wide potential applications in biotechnology. | WANG Lin CHI Zhenming YUE Lixi CHI Zhe ZHANG Dechao | 2008 | Journal of Ocean University of China2008，7，4： | 0 |
| 15 | Facile Synthesis of Yolk-Shell Bi@C Nanospheres with Superior Li-ion Storage Performances显示文摘Recently,exploring appropriate anode materials for current commercial lithium-ion batteries(LIBs) with suitable operating potential and long cycle life has attracted extensive attention.Herein,a novel anode of Bi nanoparticles fully encapsulated in carbon nanosphere framework with uniform yolk-shell nanostructure was prepared via a facile hydrothermal method.Due to the special structure design,this anode of yolk-shell Bi@C can effectively moderate the volume exchange,avoid the aggregation of active Bi nanoparticle and provide superior kinetic during discharge/charge process.Cycling in the voltage of 0.01-2.0 V,yolk-shell Bi@C anode exhibits outstanding Li+storage performance(a reversible capacity over 200 mAh g-1after 400 cycles at 1.25 A g-1) and excellent rate capability(a capacity of 404,347,304,275,240,199 and 163 mAh g-1 at0.05,0.1,0.25,0.5,1.0,1.8 and 3.2 A g-1,respectively).This work indicates that rational design of nanostructured anode materials is highly applicable for the next-generation LIBs. | Xijun Xu Dechao Zhang Zhuosen Wang Shiyong Zuo Jiadong Shen Zhengbo Liu Jun Liu | 2021 | Acta Metallurgica Sinica(English Letters)2021，34，3： | 0 |
| 16 | van der Waals type II carbon nitride homojunctions for visible light photocatalytic hydrogen evolution显示文摘Photocatalytic hydrogen evolution reaction(PC-HER)provides a solution to energy crisis and environmental pollution.Herein,different graphitic carbon nitride(g-C_(3)N_(4))-based van der Waals(vdW)type II homojunctions have been fabricated and g-C_(3)N_(4)/Kdoped g-C_(3)N_(4)nanosheets have an outstanding PC-HER rate of 1,243μmol·h^(−1)·g^(−1)under visible light,higher than that of bulk g-C_(3)N_(4),doped g-C_(3)N_(4)nanosheets,and mixed nanosheets.The enhanced PC-HER performance can be ascribed to the cooperative effects of the shortened bandgap,enlarged specific surface area,matched type II energy band structure,“face to face”vdW charge interaction,and peculiarly partite positions of the conduction and valence bands in different layers.Besides,the type II junctions were found superior to binary type II junction.This study highlights the synergistic effect of different strategies in improving the PC-HER capacities of g-C_(3)N_(4),especially the application of particular vdW junctions,and provides new insights to the structures and mechanism. | Xiaojie Li Panpan Zhang Huayang Zhang Wenjie Tian Yangyang Yang Kunsheng Hu Dechao Chen Qin Li Xiaoguang Duan Hongqi Sun Shaobin Wang | 2023 | Nano Research2023，16，4： | 0 |
| 17 | Ganoderma lucidum:a comprehensive review of phytochemistry,efficacy,safety and clinical study显示文摘Ganoderma lucidum,one of the most well-known edible fungi,is believed to be very beneficial for longevity and vitality.A long usage history suggests that G.lucidum has various clinical therapeutic effects.And experimental studies have confirmed that G.lucidum has multiple pharmacological effects,including antitumor,anti-microbial,anti-HIV protease,and antidiabetic activity and so on.With the deepening of research,more than 300 compounds have been isolated from G.lucidum.There is an increasing population of G.lucidum-based products,and its international development is expanding.Currently,G.lucidum has drawn much attention to its chemical composition,therapeutic effect,clinical value,and safety.This paper provides a comprehensive review of these aspects to enhance the global promotion of G.lucidum. | Sijia Wu Siyuan Zhang Bo Peng Dechao Tan Mingyue Wu Jinchao Wei Yitao Wang Hua Luo | 2024 | Food Science and Human Wellness2024，13，2： | 0 |
| 18 | Spacecraft formation reconfiguration with multi-obstacle avoidance under navigation and control uncertainties using adaptive artificial potential function method显示文摘In this paper,an adaptive artificial potential function(AAPF)method is developed for spacecraft formation reconfiguration with multi-obstacle avoidance under navigation and control uncertainties.Furthermore,an improved Linear Quadratic Regular(ILQR)is proposed to track the reference trajectory and a Lyapunov-based method is employed to demonstrate the stability of the overall closed-loop system.Compared with the traditional APF method and the equal-collision-probability surface(ECPS)method,the AAPF method not only retains the advantages of APF method and ECPS method,such as low computational complexity,simple analytical control law and easy analytical validation progress,but also proposes a new APF to solve multi-obstacle avoidance problem considering the influence of the uncertainties.Moreover,the ILQR controller obtains high control accuracy to enhance the safe performance of the spacecraft formation reconfiguration.Finally,the effectiveness of the proposed AAPF method and the ILQR controller are verified by numerical simulations. | Yi Wang Xiaoqian Chen Dechao Ran Yong Zhao Yang Chen Yuzhu Bai | 2020 | Astrodynamics2020，4，1： | 0 |
| 19 | Variable optical splitter based on wavelength-sensitive components and related intelligent passive optical network显示文摘 | Dechao ZHANG Han LI Lei WANG Liang GENG Shiguang WANG Sheng LIU Yang GAO | 2017 | Frontiers of Optoelectronics2017，10，1： | 0 |
| 20 | Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity显示文摘The development of new biomarkers or therapeutic targets for cancer immunotherapies requires deep understanding of Tcells.To date,the complete landscape and systematic characterization of long noncoding RNAs(lncRNAs)in T cells in cancer immunity are lacking.Here,by systematically analyzing full-length single-cell RNA sequencing(scRNA-seq)data of more than 20,000 libraries of T cells across three cancer types,we provided the first comprehensive catalog and the functional repertoires of lncRNAs in human T cells.Specifically,we developed a custom pipeline for de novo transcriptome assembly and obtained a novel lncRNA catalog containing 9433 genes.This increased the number of current human lncRNA catalog by 16%and nearly doubled the number of lncRNAs expressed in T cells.We found that a portion of expressed genes in single T cells were lncRNAs which had been overlooked by the majority of previous studies.Based on metacell maps constructed by the MetaCell algorithm that partitions scRNA-seq datasets into disjointed and homogenous groups of cells(metacells),154 signature lncRNA genes were identified.They were associated with effector,exhausted,and regulatory T cell states.Moreover,84 of them were functionally annotated based on the co-expression networks,indicating that lncRNAs might broadly participate in the regulation of T cell functions.Our findings provide a new point of view and resource for investigating the mechanisms of T cell regulation in cancer immunity as well as for novel cancer-immune biomarker development and cancer immunotherapies. | Haitao Luo Dechao Bu Lijuan Shao Yang Li Liang Sun Ce Wang Jing Wang Wei Yang Xiaofei Yang Jun Dong Yi Zhao Furong Li | 2021 | Genomics, Proteomics & Bioinformatics2021，19，3： | 0 |
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