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| 1 | 青年型开角型青光眼的中国家系的新型Myocilin基因突变显示文摘目的:探讨某中国家系青年型开角型青光眼(JOAG)的致病基因。
方法:在一个青光眼家系中,三代人中患JOAG或高眼压。我们筛查了6位家族成员Myocilin(MYOC)和 optineurin(OPTN)的突变和apolipoprotein E的多态性,2位患有JOAG,2位患有高眼压,2位无症状。正常对照组包括200位与本家系无关联的受试者。用编码野生型或变异性 MYOC 互补 DNA 的表达载体转染cos-7细胞系。细胞内或分泌的MYOC蛋白用Western法进行检测。 | Bao Jian Fan Dexter Y. L Leung Dan Yi Wang Stéphane Vincent Raymond Pancy O. S. Tam Dennis S. C. Lam Chi Pui Pang 王婷(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 5 |
| 2 | Evans syndrome in childhood显示文摘 | PUI C H WILLIMAS J WANG W | 1980 | J Pediatr1980，97，： | 1 |
| 3 | Investigation of the figure of merit for filters with a single nanofiber layer on a substrate显示文摘 | WANG J KIM S C PUI D Y H | 2008 | Journal of Aerosol Science2008，39，4： | 1 |
| 4 | Immunoregulatory abnormalities in Evans syndrome显示文摘 | WANG W C HERROD H PUI C H | 1983 | Am J Hematol1983，15，： | 1 |
| 5 | Structural Property Effect of Nanoparticle Agglomerates on Particle Penetration through Fibrous Filter显示文摘 | Seong C. Kim Jing Wang Mark S. Emery Weon Gyu Shin George W. Mulholland David Y. H. Pui | 2009 | Aerosol Science and Technology2009，，4： | 1 |
| 6 | Investigation of the figure of merit for filtration with a single nanofiher layer on a substrate 显示文摘 | WANG J KIM S C PUI D Y H | 2008 | Aerosol Science2008，39，： | 1 |
| 7 | Removal of airborne nanoparlides by membrane coated filters显示文摘 | Jingxian Liu David Y H Pui Jing Wang | 2011 | Science of the To- tal Environment2011，409，22： | 1 |
| 8 | Value of normalized apparent diffu- sion coefficient for estimating histological grade of vesical urothelial carcinoma显示文摘 | Wang H J Pui MH Guo Y | 2014 | Clinical Radiology2014，69，： | 1 |
| 9 | Association of Apolipoprotein E Polymorphisms With Normal Tension Glaucoma in a Chinese Population显示文摘 | Ching Yan Lam Bao Jian Fan Dan Yi Wang Pancy Oi Sin Tam Clement Chee Yung Tham Dexter Yu Lung Leung Dorothy Shu Ping Fan Dennis Shun Chiu Lam Chi Pui Pang | 2006 | Journal of Glaucoma2006，，3： | 1 |
| 10 | Investigation of the figure of merit for filters with a single nanofiber layer on a substrate显示文摘 | Jing Wang Seong Chan Kim David Y H Pui | 2008 | Aerosol Science2008，39，： | 1 |
| 11 | Potential Antiviral Target for SARS-CoV-2:A Key Early Responsive Kinase during Viral Entry显示文摘Currently,there is no effective antiviral medication for coronavirus disease 2019(COVID-19)and the knowledge on the potential therapeutic target is in great need.Guided by a time-course transmission electron microscope(TEM)imaging,we analyzed early phosphorylation dynamics within the first 15 min during severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)viral entry.Based on alterations in the phosphorylation events,we found that kinase activities such as protein kinase C(PKC),interleukin-1 receptor-associated kinase 4(IRAK4),MAP/microtubule affinity-regulating kinase 3(MARK3),and TANK-binding kinase 1(TBK1)were affected within 15 min of infection.Application of the corresponding kinase inhibitors of PKC,IRAK4,and p38 showed significant inhibition of SARS-CoV-2 replication.Additionally,proinflammatory cytokine production was reduced by applying PKC and p38 inhibitors.By an acquisition of a combined image data using positiveand negative-sense RNA probes,as well as pseudovirus entry assay,we demonstrated that PKC contributed to viral entry into the host cell,and therefore,could be a potential COVID-19 therapeutic target. | Siwen Liu Lin Zhu Guangshan Xie Bobo Wing-Yee Mok Zhu Yang Shaofeng Deng Siu-Ying Lau Pin Chen Pui Wang Honglin Chen Zongwei Cai | 2022 | CCS Chemistry2022，4，1： | 1 |
| 12 | Evans syndrome in child-hood显示文摘 | Pui C-H Wilimas J Wang W | 1980 | J Pediatr1980，97，5： | 1 |
| 13 | Immunoregulatory abnor-malities in Evans syndrome显示文摘 | Wang W Herrod H Pui CH | 1983 | Am J Hematol1983，15，4： | 1 |
| 14 | Investigation of the figure of merit for filters with a single nanofiber layer on a substrate显示文摘 | Jing Wang Seong Chan Kim David Y.H. Pui | 2007 | Journal of Aerosol Science2007，，4： | 1 |
| 15 | Immunoregulatory abnormalities in Evans syndrome显示文摘 | Wang W Herrod H Pui CH | 1983 | Am J Hematol1983，15，4： | 1 |
| 16 | Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoprotein 显示文摘 | Wang Pui Song Wen-jun Mok B W | 2009 | J Virol2009，83，16： | 1 |
| 17 | High performance spectral-phase surface plasmon resonance biosensors based on single anddouble-layer schemes 显示文摘 | Wang Cheng Ho Ho Pui Shum Ping | 2013 | Optics Communications2013，291，13： | 1 |
| 18 | Structure and antiviral properties of macrocaesalmin, a novel cassane furanoditerpenoid lactone from the seeds of Caesalpinia minax Hance显示文摘 | Ren Wang -Jiang Paul Pui - Hay But Shuang - Cheng Ma | 2002 | Tetrahedron Letters2002，43，： | 1 |
| 19 | Filtration of aerosol particles byelliptical fibers: a numerical study 显示文摘 | Wang J Pui D Y H | 2009 | Journal ofNanoparticle Research2009，11，1： | 1 |
| 20 | Polymer- and lipid-based nanoparticle therapeutics for the treatment of liver diseases显示文摘 | Lanjuan Li Huaying Wang Zhan Yuin Ong Kaijin Xu Pui Lai Rachel Ee Shusen Zheng James L. Hedrick Yi-Yan Yang | 2010 | Nano Today2010，，4： | 1 |
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