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| 1 | Effects of narrow plant spacing on root distribution and physiological nitrogen use efficiency in summer maize显示文摘The objective of this study was to understand the effects of plant spacing on grain yield and root competition in summer maize(Zea mays L.). Maize cultivar Denghai 661 was planted in rectangular tanks(0.54 m × 0.27 m × 1.00 m) under 27 cm(normal) and 6 cm(narrow) plant spacing and treated with zero and 7.5 g nitrogen(N) per plant. Compared to normal plant spacing, narrow plant spacing generated less root biomass in the 0–20 cm zone under both N rates, slight reductions of dry root weight in the 20–40 cm and 40–70 cm zones at the mid-grain filling stage, and slight variation of dry root weights in the 70–100 cm zone during the whole growth period. Narrow plant spacing decreased root reductive activity in all root zones, especially at the grain-filling stage. Grain yield and above-ground biomass were 5.0% and 8.4% lower in the narrow plant spacing than with normal plant spacing, although narrow plant spacing significantly increased N harvest index and N use efficiency in both grain yield and biomass, and higher N translocation rates from vegetative organs. These results indicate that the reductive activity of maize roots in all soil layers and dry weights of shallow roots were significantly decreased under narrow plant spacing conditions, resulting in lower root biomass and yield reduction at maturity. Therefore, a moderately dense sowing is a basis for high yield in summer maize. | Wenshun Jiang Kongjun Wang Qiuping Wu Shuting Dong Peng Liu Jiwang Zhang | 2013 | The Crop Journal2013，1，1： | 13 |
| 2 | Oxidative stress, nutritional antioxidants and beyond显示文摘Free radical-induced oxidative stress contributes to the development of metabolic syndromes(Mets), including overweight,hyperglycemia, insulin resistance and pro-inflammatory state. Most free radicals are generated from the mitochondrial electron transport chain;under physiological conditions, their levels are maintained by efficient antioxidant systems. A variety of transcription factors have been identified and characterized that control gene expression in response to oxidative stress status.Natural antioxidant compounds have been largely studied for their strong antioxidant capacities. This review discusses the recent progress in oxidative stress and mitochondrial dysfunction in Mets and highlights the anti-Mets, anti-oxidative, and antiinflammatory effect of polyphenols as potential nutritional therapy. | Qiuping Guo Fengna Li Yehui Duan Chaoyue Wen Wenlong Wang Lingyu Zhang Ruilin Huang Yulong Yin | 2020 | Science China(Life Sciences)2020，63，6： | 10 |
| 3 | Fluorescent nanoparticles for chemical and biological sensing显示文摘Fluorescent nanoparticles (NPs), including quantum dots (QDs), dye-doped NPs, and rare earth-based NPs, etc., have been a major focus of research and development during the past decade. The impetus behind such endeavors can be attributed to their unique chemical and optical properties, such as bright fluorescence, high photostability, large Stocks shift and flexible processability. The introduction of fluorescent NPs into analytical chemistry has opened up new venues for fluorescent analysis. In this review, we focus on the developments and analytical applications of fluorescent NPs in the chemical and biological sensing of pH, ions, organic compounds, small biological molecules, nucleic acids, proteins, virus and bacteria. The review also points out the in vitro and in vivo imaging application of fluorescent NPs at the cell and body levels. Meanwhile, the ad- vantages of NPs brought field of sensing and signal transductions are also discussed. | LIU JianBo, YANG XiaoHai, HE XiaoXiao, WANG KeMin, WANG Qing, GUO QiuPing, SHI Hui, HUANG Jin & HUO XiQin State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Institute of Biology, Hunan University Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province, Changsha 410082, China | 2011 | Science China Chemistry2011，54，8： | 9 |
| 4 | Genetic diversity,population structure,and relationships of apricot(Prunus)based on restriction site-associated DNA sequencing显示文摘Single-nucleotide polymorphisms(SNPs)are the most abundant form of genomic polymorphisms and are widely used in population genetics research.Here,high-throughput sequencing was used to examine the genome-level diversity,population structure,and relationships of apricot,which are important for germplasm conservation and molecular breeding.Restriction site-associated DNA sequencing(RAD-seq)was adopted to sequence 168 Prunus spp.accessions distributed in five ecological groups,including 74 accessions of cultivated Prunus armeniaca L.and 94 accessions of wild apricots(P.armeniaca L.and Prunus sibirica L.),which generated 417,961 high-quality SNPs.We used cluster,genetic structure,and principal component analyses to examine the genetic diversities and genetic relationships of the 168 accessions.The Dzhungar-Ili ecological group accessions showed the highest genetic diversity in terms of private allele number,observed heterozygosity,and nucleotide diversity.We speculate that the Central Asian ecological group accessions were domesticated from the Dzhungar-Ili ecological group accessions.The population structure and gene flow of the North China and European ecological group accessions suggested a genetic background of P.sibirica.We argue that the two groups should be considered hybrid swarms connected to P.sibirica by continuous and extensive gene flow.P.armeniaca originated in Northwest China(Ili Valley),subsequently spread throughout Central Asia,and eventually spread to Europe.In addition,selective sweep signatures in P.armeniaca during domestication from wild to cultivated apricots,combined with differentially expressed genes,underlie distinct fruit traits,including sugars,aromas,organic acids,and carotenoids.This study provides substantive and valuable genomic resources that will significantly advance apricot improvement and effective utilization. | Wenwen Li Liqiang Liu Yanan Wang Qiuping Zhang Guoquan Fan Shikui Zhang Yatong Wang Kang Liao | 2020 | Horticulture Research2020，7，1： | 9 |
| 5 | Optimizing water and nitrogen inputs for winter wheat cropping system on the Loess Plateau,China显示文摘Optimal use of water and fertilizers can enhance winter wheat yield and increase the efficiencies of water and fertilizer usage in dryland agricultural systems.In order to optimize water and nitrogen(N)management for winter wheat,we conducted field experiments from 2006 to 2008 at the Changwu Agro-ecological Experimental Station of the Chinese Academy of Sciences on the Loess Plateau,China.Regression models of wheat yield and evapotranspiration(ET)were established in this study to evaluate the water and fertilizer coupling effects and to determine the optimal coupling domain.The results showed that there was a positive effect of water and N fertilizer on crop yield,and optimal irrigation and N inputs can significantly increase the yield of winter wheat.In the drought year(2006–2007),the maximum yield(Ymax)of winter wheat was 9.211 t/hm2for the treatment with 324 mm irrigation and 310 kg/hm2N input,and the highest water use efficiency(WUE)of 16.335 kg/(hm2 mm)was achieved with198 mm irrigation and 274 kg/hm2N input.While in the normal year(2007–2008),the maximum winter wheat yield of 10.715 t/hm2was achieved by applying 318 mm irrigation and 291 kg/hm2N,and the highest WUE was 18.69kg/(hm2 mm)with 107 mm irrigation and 256 kg/hm2N input.Crop yield and ET response to irrigation and N inputs followed a quadratic and a line function,respectively.The optimal coupling domain was determined using the elasticity index(EI)and its expression in the water-N dimensions,and was represented by an ellipse,such that the global maximum WUE(WUEmax)and Ymax values corresponded to the left and right end points of the long axis,respectively.Considering the aim to get the greatest profit in practice,the optimal coupling domain was represented by the lower half of the ellipse,with the Ymax and WUEmax on the two end points of the long axis.Overall,we found that the total amount of irrigation for winter wheat should not exceed 324 mm.In addition,our optimal coupling domain visually reflects the optimal range of water and N inputs for the maximum winter wheat yield on the Loess Plateau,and it may also provide a useful reference for identifying appropriate water and N inputs in agricultural applications. | QiuPing FU QuanJiu WANG XinLei SHEN Jun FAN | 2014 | Journal of Arid Land2014，6，2： | 8 |
| 6 | G protein-coupled receptor 183 facilitates endothelial-to- hematopoietic transition via Notch1 inhibition显示文摘 | Panpan Zhang Qiuping He Dongbo Chen Weixiao Liu Lu Wang Chunxia Zhang Dongyuan Ma Wei Li Bing Liu Feng Liu | 2015 | Cell Research2015，25，10： | 7 |
| 7 | Optimal configuration for photovoltaic storage system capacity in 5G base station microgrids显示文摘Base station operators deploy a large number of distributed photovoltaics to solve the problems of high energy consumption and high electricity costs of 5G base stations.In this study,the idle space of the base station’s energy storage is used to stabilize the photovoltaic output,and a photovoltaic storage system microgrid of a 5G base station is constructed.Aiming at the capacity planning problem of photovoltaic storage systems,a two-layer optimal configuration method is proposed.The inner layer optimization considers the energy sharing among the base station microgrids,combines the communication characteristics of the 5G base station and the backup power demand of the energy storage battery,and determines an economic scheduling strategy for each photovoltaic storage system with the goal of minimizing the daily operation cost of the base station microgrid.The outer model aims to minimize the annual average comprehensive revenue of the 5G base station microgrid,while considering peak clipping and valley filling,to optimize the photovoltaic storage system capacity.The CPLEX solver and a genetic algorithm were used to solve the two-layer models.Considering the construction of the 5G base station in a certain area as an example,the results showed that the proposed model can not only reduce the cost of the 5G base station operators,but also reduce the peak load of the power grid and promote the local digestion of photovoltaic power. | Xiufan Ma Ying Duan Xiangyu Meng Qiuping Zhu Zhi Wang Sijia Zhu | 2021 | Global Energy Interconnection2021，4，5： | 5 |
| 8 | The diagnostic rules of peripheral lung cancer preliminary study based on data mining technique显示文摘Objective: To discuss the clinical and imaging diagnostic rules of peripheral lung cancer by data mining technique, and to explore new ideas in the diagnosis of peripheral lung cancer, and to obtain early-stage technology and knowledge support of computer-aided detecting(CAD). Methods: 58 cases of peripheral lung cancer confirmed by clinical pathology were collected. The data were imported into the database after the standardization of the clinical and CT findings attributes were identified. The data was studied comparatively based on Association Rules (AR) of the knowledge discovery process and the Rough Set (RS) reduction algorithm and Genetic Algorithm(GA) of the generic data analysis tool (ROSETTA), respectively. Results: The genetic classification algorithm of ROSETTA generates 5 000 or so diagnosis rules. The RS reduction algorithm of Johnson`s Algorithm generates 51 diagnosis rules and the AR algorithm generates 123 diagnosis rules. Three data mining methods basically consider gender, age, cough, location, lobulation sign, shape, ground-glass density attributes as the main basis for the diagnosis of peripheral lung cancer. Conclusion: These diagnosis rules for peripheral lung cancer with three data mining technology is same as clinical diagnostic rules, and these rules also can be used to build the knowledge base of expert system. This study demonstrated the potential values of data mining technology in clinical imaging diagnosis and differential diagnosis. | Yongqian Qiang Youmin Guo Xue Li Qiuping Wang Hao Chen Duwu Cui | 2007 | Journal of Nanjing Medical University2007，21，3： | 5 |
| 9 | Fine mapping of cisc(t),a gene for cold-induced seedling chlorosis,and identification of its candidate in rice显示文摘The seedlings of indica rice cultivar Dular are susceptible to chlorosis under low temperature conditions.Our previous studies indicated that low temperature-induced seedling chlorosis is controlled by a recessive gene,located between SSR markers RM257 and RM242,on the long arm of chromosome 9.We temporarily named the gene cisc(t).Using a large F2 population derived from a cross between Dular and the japonica cultivar Lemont,which displays a normal green color at low temperatures,cisc(t)was fine mapped to within a 12-kb interval.There is only one annotated gene in this interval,which encodes a pentatricopeptide repeat(PPR)protein.Sequence analysis indicated that 8 bases were deleted at the 60th base in the Dular allele,resulting in a frame-shift mutation and loss of function of the gene.This is consistent with the chlorosis mutant phenotype of Dular.In addition,previous studies have shown that many chlorosis mutants of seedlings are related to PPR proteins.Hence,we presume that the PPR gene is the candidate for cisc(t). | LAN Tao WANG Bin LING QiuPing XU ChunHua TONG ZhiJun LIANG KangJing DUAN YuanLin JIN Jing WU WeiRen | 2010 | Chinese Science Bulletin2010，55，27： | 5 |
| 10 | Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets显示文摘Background: Oxidative stress is a key factor that influences piglets' health. Taurine plays an imperative role in keeping the biological system from damage. This study was conducted to investigate the protective effect of taurine against muscle injury due to the secondary effect of diquat toxicity.Results: Our study found that taurine effectively and dose-dependently alleviated the diquat toxicity induced rise of feed/gain, with a concurrent improvement of carcass lean percentage. The plasma content of taurine was considerably increased in a dose-dependent manner. Consequently, dietary taurine efficiently improved the activity of plasma antioxidant enzymes. Furthermore, taurine attenuated muscle damage by restoring mitochondrial micromorphology, suppressing protein degradation and reducing the percentage of apoptotic cells in the skeletal muscle. Taurine supplementation also suppressed the genes expression levels of the antioxidant-, mitochondrial biogenesis-, and muscle atrophy-related genes in the skeletal muscle of piglets with oxidative stress.Conclusions: These results showed that the dose of 0.60% taurine supplementation in the diet could attenuate skeletal muscle injury induced by diquat toxicity. It is suggested that taurine could be a potential nutritional intervention strategy to improve growth performance. | Chaoyue Wen Fengna Li Qiuping Guo Lingyu Zhang Yehui Duan Wenlong Wang Jianzhong Li Shanping He Wen Chen Yulong Yin | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 5 |
| 11 | Phaeocystis globosa Bloom Monitoring: Based on P. globosa Induced Seawater Viscosity Modification Adjacent to a Nuclear Power Plant in Qinzhou Bay, China显示文摘The mucus produced by the outbreak of Phaeocystis globosa in the adjacent waters of the Fangchenggang Nuclear Power Plant(FCGNPP) in China has blocked the entrance of the cooling water filtration system of the FCGNPP, and posed a threat to the safe operation of the FCGNPP. At present, there is no related research on whether the changes in seawater viscosity could be used as a new method for monitoring and providing early warning of P. globosa tide. During a complete red tide cycle, the temporal and spatial changes in the hydrological conditions(temperature, salinity, dissolved oxygen), chlorophyll-a(Chl-a), composition and abundance of phytoplankton, number and size of P. globose colonies, concentration of transparent exopolymer particles(TEP) and the seawater viscosity were measured in this study. The results indicate that there was an extremely significant negative correlation between the physical seawater viscosity η_(T,S) and temperature, and the correlation coefficient reached-0.998. The biological seawater viscosity η_(Bio) was positively correlated with the number of P. globosa colonies, and the correlation coefficients is 0.747. Because the increase in phytoplankton abundance, especially during the outbreak of P. globosa and a large amount of mucus produced by the colonies could significantly increase seawater viscosity, we suggest that biological factors were the main reasons for the increase in seawater viscosity. The η_(Bio) was completely consistent with the occurrence process of P. globosa bloom and could be used as a valuable index for P. globosa bloom monitoring. | KANG Zhenjun YANG Bin LAI Junxiang NING Yi ZHONG Qiuping LU Dongliang LIAO Riquan WANG Pei Solomon Felix Dan SHE Zhicai JIA Zhen LAO Yanling LI Nan | 2020 | Journal of Ocean University of China2020，19，5： | 5 |
| 12 | Optimal configuration of 5G base station energy storage considering sleep mechanism显示文摘The high-energy consumption and high construction density of 5G base stations have greatly increased the demand for backup energy storage batteries.To maximize overall benefits for the investors and operators of base station energy storage,we proposed a bi-level optimization model for the operation of the energy storage,and the planning of 5G base stations considering the sleep mechanism.A multi-base station cooperative system composed of 5G acer stations was considered as the research object,and the outer goal was to maximize the net profit over the complete life cycle of the energy storage.Furthermore,the power and capacity of the energy storage configuration were optimized.The inner goal included the sleep mechanism of the base station,and the optimization of the energy storage charging and discharging strategy,for minimizing the daily electricity expenditure of the 5G base station system.Additionally,genetic algorithm and mixed integer programming were used to solve the bi-level optimization model,analyze the numerical example test comparison of the three types of batteries and the net income of the configuration,and finally verify the validity of the model.Furthermore,the sleep mechanism,the charging and discharging strategy for energy consumption,and the economic benefits for the operators were investigated to provide reference for the 5G base station energy storage configuration. | Xiufan Ma Qiuping Zhu Ying Duan Xiangyu Meng Zhi Wang | 2022 | Global Energy Interconnection2022，5，1： | 4 |
| 13 | Ribozyme probe based on molecular beacon for real time monitoring of enzymatic cleavage process显示文摘Ribozyme probe based on molecular beacon (MBR) for monitoring enzymatic cleavage process in real time is designed and studied. The approach relies on ri-bozyme substrates modified at the two arms, with a fluores-cent moiety attached to the end of one arm and a non-fluorescent quenching moiety attached to the end of the other arm. MBR is employed to directly convert the cleavage information into fluorescence signal in real time. Compared with traditional approach, this method provides a no-radiolabeling, sensitive and effective way to research on the ribozyme activity, enzymatic dynamic process and ri-bozyme function during gene therapy. The activity of the ribozyme against hepatitis C virus RNA (HCV-RNA) is stud-ied based on this assay. | MENG Xiangxian, WANG Kemin, TAN Weihong, LI Jun, TANG Zhiwen, GUO Qiuping, HUANG Shasheng & LI Du State Key Laboratory of Chemo/Biosensing and Chemometrics, Institute of Biological Technology, College of Chemistry and Chemical Engi-neering, Hunan University, Changsha 410082, China Correspondence should be addressed to Wang Kemin (e-mail: kmwang @hnu.net.cn) | 2003 | Chinese Science Bulletin2003，48，23： | 3 |
| 14 | English and Chinese language frequency time series analysis显示文摘English and Chinese language frequency time series (LFTS) were constructed based on an English and two Chinese novels. Methods of statistical hypothesis testing were adopted to test the nonlinear properties of the LFTS. Results suggest the series exhibited non-normal, auto-correlative, and stationary characteristics. Moreover, we found that LFTS follow the power law distributions, and thereby we investigated the fractal structure, long range correlation, and intermittency, which indicated the self-similarity features of LFTS, and also provided hints that human societies are likely to share some universal properties. | DENG WeiBing WANG DuJuan LI Wei WANG Qiuping Alexandre | 2011 | Chinese Science Bulletin2011，56，34： | 3 |
| 15 | Epoxidized methyl ricinoleate bio-plasticizer with a pendant acetate ester for PVC artificial material:circumventing existing limit on achievable migration resistance显示文摘Processing polyvinyl chloride(PVC)artificial material requires plasticizer that softens the PVC coating.Currently,utilizing unsaturated fatty acid methyl esters to obtain epoxidized fatty acid methyl ester(EFAME)bio-plasticizers constitutes an environmentally responsible solution to substitute conventional ortho-phthalates that are endocrine disruptors or probable carcinogens.However,commercial EFAMEs,even with the highest epoxy value(ca.5.5-5.8%)so far,still suffer from fast leaching from the PVC matrix,burdening the environment and shortening lifespan of the artificial material.Here,we report a proof-of-principle demonstration of a new strategy to obtain migration-resistant EFAME that harnesses the midchain hydroxyl of methyl ricinoleate and covalently attachment of a pendant acetate ester.Despite a low epoxy value(3.0%),the engineered bio-plasticizer displays significantly suppressed migration in multiple scenarios compared with one conventional EFAME with much higher epoxy value(5.8%).Circumventing the limit confronting previous strategy that highlights the sole contribution of epoxy value to achievable migration resistance,the rationale herein may provide guidance for designing new EFAMEs with comparable performance to ortho-phthalates,thus bringing the old and oft-maligned PVC artificial material industry one step closer to sustainability. | Siyu Pan Delong Hou Gaofu Yang Qiuping Xie Sunxian Yan Qi Zeng Zhonghui Wang Yi Chen Haojun Fan | 2019 | Journal of Leather Science and Engineering2019，1，1： | 3 |
| 16 | Novel protein detection method based on proximity- dependent polymerase reaction and aptamers显示文摘In recent years, specific detection of proteins is one of the hot issues about aptamers in proteomics. Here we reported a simple, sensitive and specific proximity-dependent protein assay with dual DNA aptamers. Thrombin was used as the model protein, and two aptamer probes with complementary se- quence at 3′-end were designed for the two distinct epitopes of the protein. Association of the two ap- tamers with thrombin resulted in stable hybrids due to the proximity of 3′-end, then polymerase reac- tion was induced. The amount of obtained dsDNA was indicated using the fluorescence dye Sybr Green I. The results showed that the initial velocity of polymerase reaction had a positive correlation with concentration of thrombin. The advantages of this dual-aptamer-based approach included simple and flexible design of aptamer probes, high selectivity and high sensitivity. The detection limit was 6.9 pmol/L. | YANG XiaoHai WANG Lei WANG KeMin TAN WeiHong TANG HongXing MENG XiangXian GUO QiuPing | 2008 | Chinese Science Bulletin2008，53，2： | 3 |
| 17 | Protein analysis based on molecular beacon probes and biofunctionalized nanoparticles显示文摘With the completion of the human genome-sequencing project, there has been a resulting change in the focus of studies from genomics to proteomics. By utilizing the inherent advantages of molecular beacon probes and biofunctionalized nanoparticles, a series of novel principles, methods and techniques have been exploited for bioanalytical and biomedical studies. This review mainly discusses the applications of molecular beacon probes and biofunctionalized nanoparticles-based technologies for realtime, in-situ, highly sensitive and highly selective protein analysis, including the nonspecific or specific protein detection and separation, protein/DNA interaction studies, cell surface protein recognition, and antigen-antibody binding process-based bacteria assays. The introduction of molecular beacon probes and biofunctionalized nanoparticles into the protein analysis area would necessarily advance the proteomics research. | SHI Hui, HE XiaoXiao, YANG XiaoHai, WANG KeMin, WANG Qing, GUO QiuPing & HUO XiQin State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering, Biomedical Engineering Center, Hunan University Key Laboratory for Bio-Nanotechnology and Molecule Engineering of Hunan Province, Changsha 410082, China | 2010 | Science China Chemistry2010，53，4： | 2 |
| 18 | Epidemiology of severe sepsis in critically ill surgical patients in ten university hospitals in China显示文摘 | Baoli Cheng Guohao Xie ShangLong Yao Xinmin Wu Qulian Guo Miaoning Gu Qiang Fang Qiuping Xu Dongxin Wang Yuhong Jin ShiYing Yuan Junlu Wang Zhaohui Du Yunbo Sun XiangMing Fang | 2007 | Critical Care Medicine2007，，11： | 2 |
| 19 | Isolation and identification of multidrug-resistant Staphylococcus haemolyticus from a laboratory-breeding mouse显示文摘Objective:To analysis and identify a bacterium strain isolated from laboratory breeding mouse far away from a hospital.Methods:Phenotype of the isolate was investigated by conventional microbiological methods,including Gram-staining,colony morphology,tests for haemolysis, catalase,coagulase,and antimicrobial susceptibility test.The meek and 16S rRNA genes were amplified by the polymerase chain reaction(PCR) and sequenced.The base sequence of the PCR product was compared with known 16S rRNA gene sequences in the CenBank database by phylogenetic analysis and multiple sequence alignment.Results:The isolate in this study was a gram positive,coagulase negative,and catalase positive coccus.The isolate was resistant to oxacillin,methicillin,penicillin,ampicillin,cefazolin,cipr of loxacin erythromycin,et al.PCR results indicated that the isolate was meek gene positive and its 16S rRNA was 1465 bp.Phylogenetic analysis of the resultant 16S rRNA indicated the isolate belonged to genus Saphylococcus,and multiple sequence alignment showed that the isolate was Saphylococcus haemolyticus with only one base difference from the corresponding 16S rRNA deposited in the CenBank.Conclusions: 16S rRNA gene sequencing is a suitable technique for non-specialist researchers.Laboratory animals are possible sources of lethal pathogens,and researchers must adapt protective measures when they manipulate animals. | Fengying Huang Qiuping Meng Guanghong Tan Yonghao Huang Hua Wang Wenli Mei Haofu Dai | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 2 |
| 20 | Prediction Model of Coal Reservoir Pressure and its Implication for the Law of Coal Reservoir Depressurization显示文摘The main methods of coalbed methane(CBM)development are drainage and depressurization,and a precise prediction of coal reservoir pressure is thus crucial for the evaluation of reservoir potentials and the formulation of reasonable development plans.This work established a new reservoir pressure prediction model based on the material balance equation(MBE)of coal reservoir,which considers the self-regulating effects of coal reservoirs and the dynamic change of equivalent drainage area(EDA).According to the proposed model,the reservoir pressure can be predicted based on reservoir condition data and the actual production data of a single well.Compared with traditional reservoir pressure prediction models which regard EDA as a fixed value,the proposed model can better predict the average pressure of reservoirs.Moreover,orthogonal experiments were designed to evaluate the sensitivity of reservoir parameters on the reservoir pressure prediction results of this proposed model.The results show that the saturation of irreducible water is the most sensitive parameter,followed by Langmuir volume and reservoir porosity,and Langmuir pressure is the least sensitive parameter.In addition,the pressure drop of reservoirs is negatively correlated with the saturation of irreducible water and the Langmuir volume,while it is positively correlated with porosity.This work analyzed the reservoir pressure drop characteristics of the CBM wells in the Shizhuangnan Block of the Qinshui Basin,and the results show that the CBM reservoir depressurization can be divided into three types,i.e.,rapidly drop type,medium-term stability type,and slowly drop type.The drainage features of wells were reasonably interpreted based on the comprehensive analysis of the reservoir depressurization type;the latter was coupled to the corresponding permeability dynamic change characteristics,eventually proving the applicability of the proposed model. | YAN Xinlu ZHANG Songhang TANG Shuheng LI Zhongcheng WANG Kaifeng YI Yongxiang DANG Feng HU Qiuping | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 2 |
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