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| 1 | An attack on hash function HAVAL-128显示文摘In this paper, we give a fast attack against hash function——HAVAL-128.HAVAL was presented by Y. L. Zheng et al. at Auscrypto’92. It can be processed in 3, 4 or 5 passes, and produces 128, 160, 192, or 224-bit fingerprint. We break the HAVAL with 128-bit fingerprint. The conclusion is that, given any 1024-bit message m, we just make some modifications about m, and the modified message m can collide with another message m’ only with probability 1/27, where m’ = m + △m, in which Am is a fixed difference selected in advance. In addition, two collision examples for HAVAL-128 are given in this paper. | WANG Xiaoyun FENG Dengguo YU Xiuyuan | 2005 | Science in China(Series F)2005，48，5： | 9 |
| 2 | Molecular characteristics of the omp A gene of serotype B Chlamydia trachomatis in Qinghai Tibetan primary school students显示文摘To study the molecular characteristics of Chlamydia trachomatis, the major outer membrane protein gene(omp A) of C. trachomatis from primary school students with trachoma residing in the Qinghai Tibetan area was sequenced and compared with the same serotype in Gen Bank. In Jianshetang Primary School and Galeng Central Primary School in the Galeng Tibetan Township of Qinghai Haidong Sala Autonomous County, scraped samples were collected from the upper tarsal conjunctiva and lower conjunctival sac of both eyes of 45 students with trachoma, stored at 4°C, and transported to Beijing Tongren Hospital by air within 24 h. The samples were screened for C. trachomatis by real-time PCR. The omp A gene from the C. trachomatis-positive samples was amplified by nested PCR. The serotype was confirmed by National Center for Biotechnology Information(NCBI) BLAST search and homology analysis. The entire omp A gene sequence was compared with the corresponding gene sequences of serotype B strains available in Gen Bank. Of the 45 students aged 6–13 years with trachoma, 26 C. trachomatis-positive students were identified by the initial real-time PCR screening(average age,(9.09±1.63) years; sex ratio, 1.0), accounting for 57.78%(26/45). The cycle threshold values for real-time PCR were 16.79–37.77. Half(13/26) of C. trachomatis-positive students had a bacterial copy number of >105. The compliance rate of the omp A gene sequences with the C. trachomatis serotype B strains in Gen Bank was up to 99%. Two novel genetic mutations were found when the omp A gene was compared with those of the 11 serotype B strains in Gen Bank. The two non-synonymous mutations were located at(i) position 271 in the second constant domain, an adenine(A) to guanine(G) substitution(ACT?GCT), changing the amino acid at position 91 from threonine to alanine(Thr?Ala) in all 26 strains; and(ii) position 887 in the fourth variable domain, a cytosine(C) to thymine(T) substitution(GCA?GTA), changing the amino acid at residue 296 from alanine to valine(Ala?Val) in four of the 26 strains. Six mutations were identified relative to ATCC VR-573. The strains could be divided into two gene clusters according to the mutation at nucleotide position 887: CQZ-1(China Qinghai Tibetan-1) and CQZ-2(China Qinghai Tibetan-2). We thus detected two novel serotype B mutant strains of C. trachomatis among study subjects with trachoma. | Xue Li Shaoya Zhang Qingfeng Liang Mei Wang Ailian Hu Xiuyuan Li Benshan Yang Mingxin Zhang Ningli Wang Xinxin Lu | 2016 | Science China(Life Sciences)2016，59，6： | 6 |
| 3 | A wave of Foxp3^(+) regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance显示文摘Newborn animals require tightly regulated local and systemic immune environments to govern the development and maturation of multiple organs/tissues even though the immune system itself is far from mature during the neonatal period.Regulatory T cells(Tregs)are essential for maintaining immune tolerance/homeostasis and modulating inflammatory responses.The features of Tregs in the neonatal liver under steady-state conditions are not well understood.The present study aimed to investigate the phenotype,functions,and significance of neonatal Tregs in the liver.We found a wave of thymus-derived Treg influx into the liver during 1–2 weeks of age.Depletion of these Tregs between days 7 and 11 after birth rapidly resulted in Th1-type liver inflammation and metabolic disorder.More Tregs in the neonatal liver than in the spleen underwent MHC II-dependent activation and proliferation,and the liver Tregs acquired stronger suppressive functions.The transcriptomic profile of these neonatal liver Tregs showed elevated expression of PPARγand T-bet and features of Tregs that utilize lipid metabolic machinery and are capable of regulating Th1 responses.The accumulation of Tregs with unique features in the neonatal liver is critical to ensure self-tolerance and liver maturation. | Mingyang Li Weijia Zhao Yifan Wang Lixue Jin Gaowen Jin Xiuyuan Sun Wei Wang Ke Wang Xi Xu Jie Hao Rong Jin Wenxian Fu Ying Sun Yingjun Chang Xiaojun Huang Xuyu Zhou Hounan Wu Kunshan Zhang Qing Ge | 2020 | Cellular & Molecular Immunology2020，17，5： | 4 |
| 4 | IMPROVEMENT OF NONREPUDIABLE THRESHOLD MULTI-PROXY THRESHOLD MULTI-SIGNATURE SCHEME WITH SHARED VERIFICATION显示文摘In 2005, Bao, et al. [Appl. Math. and Comput., vol.169, No.2, 2005] showed that Tzeng, et al.’s nonrepudiable threshold multi-proxy multi-signature scheme with shared verification was insecure, and proposed an improved scheme with no Share Distribution Center (SDC). This paper shows that Bao, et al.’s scheme suffers from the proxy relationship inversion attack and forgery attack, and pro- poses an improvement of Bao, et al.’s scheme. | Xie Qi Wang Jilin Yu Xiuyuan | 2007 | Journal of Electronics(China)2007，24，6： | 2 |
| 5 | TRAF3IP3 at the trans-Golgi network regulates NKT2 maturation via the MEK/ERK signaling pathway显示文摘Thymic natural killer T(NKT)2 cells are a subset of invariant NKT cells with PLZF^(hi)GATA3^(hi)IL-4^(+).The differentiation of NKT2 cells is not fully understood.In the present study,we report an important role of TRAF3-interacting protein 3(TRAF3IP3)in the functional maturation and expansion of committed NKT2s in thymic medulla.Mice with T-cell-specific deletion of TRAF3IP3 had decreased thymic NKT2 cells,decreased IL-4-producing peripheral iNKTs,and defects in response toα-galactosylceramide.Positive selection and high PLZF expression in CD24^(+)CD44^(−) and CCR7^(+)CD44^(−) immature iNKTs were not affected.Only CD44^(hi)NK1.1^(−) iNKTs in Traf3ip3^(−/−) mice showed reduced expression of Egr2,PLZF,and IL-17RB,decreased proliferation,and reduced IL-4 production upon stimulation.This Egr2 and IL-4 expression was augmented by MEK1/ERK activation in iNKTs,and TRAF3IP3 at the trans-Golgi network recruited MEK1 and facilitated ERK phosphorylation and nuclear translocation.LT βR-regulated bone marrow-derived nonlymphoid cells in the medullary thymic microenvironment were required for MEK/ERK activation and NKT2 maturation.These data demonstrate an important functional maturation process in NKT2 differentiation that is regulated by MEK/ERK signaling at the trans-Golgi network. | Xinwei Zhang Ke Wang Weijia Zhao Li Cao Shusong Zhang Rong Jin Xiuyuan Sun Jie Hao Xiaojun Huang Mingzhao Zhu Hounan Wu Hongshan Zhao Qing Ge | 2020 | Cellular & Molecular Immunology2020，17，4： | 2 |
| 6 | A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides based on fluorescence antiquenching显示文摘Balancing the risks and benefits of organophosphate pesticides(OPs)on human and environmental health relies partly on their accurate measurement.A highly sensitive fluorescence anti-quenching multi-residue bio-barcode immunoassay was developed to detect OPs(triazophos,parathion,and chlorpyrifos)in apples,turnips,cabbages,and rice.Gold nanoparticles were functionalized with monoclonal antibodies against the tested OPs.DNA oligonucleotides were complementarily hybridized with an RNA fluorescent label for signal amplification.The detection signals were generated by DNA-RNA hybridization and ribonuclease H dissociation of the fluorophore.The resulting fluorescence signal enables multiplexed quantification of triazophos,parathion,and chlorpyrifos residues over the concentration range of 0.01-25,0.01-50,and 0.1-50 ng/mL with limits of detection of 0.014,0.011,and 0.126 ng/mL,respectively.The mean recovery ranged between 80.3% and 110.8% with relative standard deviations of 7.3%-17.6%,which correlate well with results obtained by liquid chromatography-tandem mass spectrometry(LC-MS/MS).The proposed bio-barcode immunoassay is stable,reproducible and reliable,and is able to detect low residual levels of multi-residue OPs in agricultural products. | Lingyuan Xu Xiuyuan Zhang A.M.Abd El-Aty Yuanshang Wang Zhen Cao Huiyan Jia J.-Pablo Salvador Ahmet Hacimuftuoglu Xueyan Cui Yudan Zhang Kun Wang Yongxin She Fen Jin Lufei Zheng Baima Pujia Jing Wang Maojun Jin Bruce D.Hammock | 2022 | Journal of Pharmaceutical Analysis2022，12，4： | 1 |
| 7 | Defect engineering for high-selection-performance of NO reduction to NH3 over CeO_(2)(111)surface:A DFT study显示文摘To reduce the greenhouse effect caused by the surgery of nitrogen-oxides concentration in the atmosphere and develop a future energy carrier of renewables,it is very critical to develop more efficient,controllable,and highly sensitive catalytic materials.In our work,we proposed that nitric oxide(NO),as a supplement to N_(2) for the synthesis of ammonia,which is equipped with a lower barrier.And the study highlighted the potential of CeO_(2)(111)nanosheets with La doping and oxygen vacancy(OV)as a high-performance,controllable material for NO capture at the site of Vo site,and separation the process of hydrogenation.We also reported that the E_(ads) of-1.12 eV with horizontal adsorption and the Bader charge of N increasing of 0.53|e|and O increasing of 0.17|e|at the most active site of reduction-OV predicted.It is worth noting thatΔG of NORR(NO reduction reaction)shows good performance(thermodynamically spontaneous reaction)to synthesize ammonia and water at room temperature in the theoretical calculation. | Chaozheng He Risheng Sun Ling Fu Jinrong Huo Chenxu Zhao Xiuyuan Li Yan Song Sumin Wang | 2022 | Chinese Chemical Letters2022，33，1： | 1 |
| 8 | Microorganisms of the High--Temperature Liaohe Oil/ield of China and Their Potential for MEOR显示文摘 | Nazina T N Xue Yanfen Wang Xiuyuan | 2000 | Resource Environ Biotechnol2000，3，1： | 1 |
| 9 | The application of artificial intelligence and radiomics in lung cancer显示文摘Lung cancer is one of the most leading causes of death throughout the world,and there is an urgent requirement for the precision medical management of it.Artificial intelligence(AI)consisting of numerous advanced techniques has been widely applied in the field of medical care.Meanwhile,radiomics based on traditional machine learning also does a great job in mining information through medical images.With the integration of AI and radiomics,great progress has been made in the early diagnosis,specific characterization,and prognosis of lung cancer,which has aroused attention all over the world.In this study,we give a brief review of the current application of AI and radiomics for precision medical management in lung cancer. | Yaojie Zhou Xiuyuan Xu Lujia Song Chengdi Wang Jixiang Guo Zhang Yi Weimin Li | 2020 | Precision Clinical Medicine2020，3，3： | 1 |
| 10 | Oligocarpia kepingensis sp.nov.from the Lower Permian of the northern Tarim Basin,Xinjiang and its in situ spores显示文摘A Palaeozoic gleicheniaceous fern Oligocarpia kepingensis sp. nov. is described from the Lower Permian of the northern Tarim Basin, Xinjiang, China. The material comprises fertile organs including sori, sporangia, spores and associated sterile leaf of the Sphenopteris type. The sori are circular and 0.6—0.8 mm in diameter, and each sorus consists of 4—6 oval sporangia without an indusium. A transverse annulus completely encircles the sporangium. Each sporangium produces probably 256 trilete spores resembling the dispersed genus Leiotriletes. Comparisons are made between O. kepingensis and other species of Oligocarpia in the soral organization and spores. It is reasonable to include Oligocarpia in Gleicheniaceae based on its similarities of fertile character to the extant gleicheniaceous members. | Yongdong Wang Xiuyuan Wu | 1999 | Chinese Science Bulletin1999，44，2： | 1 |
| 11 | The Age and Character of the Yu'erhong Flora from Yumen, Gansu显示文摘From a fresh field investigation, it has been ascertained that the Late Palaeozoic Yu’erhong (Yuernhung) flora from Yu’erhong, Yumen, Gansu, northwestern China, studied by Bohlin in 1971 includes plants from the Westphalian Yangfukou Formation and the Stephanian to Sakmarian Taiyuan Formation. The Yu’erhong flora from the Yanghukou Formation is dominated by Euramerican elements with a few elements of the Cathaysian flora. No Angarian elements have be found in this section for lack of Late Permian strata. The specimens studied by Bohlin might possibly come from the upper part of the Upper Permian at tne southeastern corner . of the Yu’erhong basin. Those fossils from different horizons and localities might be mixed with each other during collection ;so they fail to reflect the exact horizon of certain plant fossils. | Shen Guanglong, Wu Xiuyuan, Wang Jun and Liu Huaqin Department of Geology, Northwest U niversity, Xi’an, Shaanxi Nanjing Institute of Geology and Palaeontology,Chinese Academy of Sciences, Nanjing, Jiangsu | 1995 | Acta Geologica Sinica(English Edition)1995，69，3： | 0 |
| 12 | Calling for improved pulmonary and critical care medicine in China and beyond显示文摘Infectious and chronic respiratory diseases place a high burden on both individual patients and the health system.For instance,lower respiratory infections count among the leading causes of death worldwide.1 The emergence within the past two decades of several newly identified coronaviruses. | Chen Wang Xiuyuan Hao Simiao Chen | 2023 | Chinese Medical Journal Pulmonary and Critical Care Medicine2023，1，1： | 0 |
| 13 | Image dehazing based on dark channel prior and brightness enhancement for agricultural monitoring显示文摘Obtaining clear and true images is a basic requirement for agricultural monitoring.However,under the influence of fog,haze and other adverse weather conditions,captured images are usually blurred and distorted,resulting in the difficulty of target extraction.Traditional image dehazing methods based on image enhancement technology can cause the loss of image information and image distortion.In order to address the above-mentioned problems caused by traditional image dehazing methods,an improved image dehazing method based on dark channel prior(DCP)was proposed.By enhancing the brightness of the hazed image and processing the sky area,the dim and un-natural problems caused by traditional image dehazing algorithms were resolved.Ten different test groups were selected from different weather conditions to verify the effectiveness of the proposed algorithm,and the algorithm was compared with the commonly-used histogram equalization algorithm and the DCP method.Three image evaluation indicators including mean square error(MSE),peak signal to noise ratio(PSNR),and entropy were used to evaluate the dehazing performance.Results showed that the PSNR and entropy with the proposed method increased by 21.81%and 5.71%,and MSE decreased by 40.07%compared with the original DCP method.It performed much better than the histogram equalization dehazing method with an increase of PSNR by 38.95%and entropy by 2.04%and a decrease of MSE by 84.78%.The results from this study can provide a reference for agricultural field monitoring. | Xiuyuan Wang Chenghai Yang Jian Zhang Huaibo Song | 2018 | International Journal of Agricultural and Biological Engineering2018，11，2： | 0 |
| 14 | Constructing a novel Ag nanowire@CeVO_(4) heterostructure photocatalyst for promoting charge separation and sunlight driven photodegradation of organic pollutants显示文摘Exploiting efficient and recyclable photocatalysts is a vital matter for environmental purification. Herein, cerium vanadate (CeVO_(4)) sub-microspheres and silver nanowire (AgNW)@CeVO_(4) with core-shell architecture as photocatalysts are rationally constructed by hydrothermal approach. The AgNW@CeVO_(4) photocatalyst obtained by depositing CeVO_(4) on the surface of Ag NWs possess one dimensional continuous structure, which expand the optical absorption range and reduce the band gap of CeVO_(4) photocatalyst. Moreover, the resultant AgNW@CeVO_(4) photocatalyst demonstrates superior photocatalytic performance in the degradation of rhodamine B, methylene blue, and 4-nitrophenol pollutants upon solar light irradiation, compared with pure CeVO_(4). The excellent photocatalytic activity can be ascribed to the introduction of Ag NWs, which afford rapid charge transport channels and reservoir for the electrons in the AgNW@CeVO_(4) heterostructure to promote separation of electron-hole pairs. The first-principles investigations reveal increase of adsorption energy of oxygen molecules on the CeVO_(4) surface with the presence of Ag. Meanwhile, Ag NWs can further improve the photocatalytic efficiency of the AgNW@CeVO_(4) based on the plasmonic effect. More importantly, the good structural stability and recyclability of AgNW@CeVO_(4) are observed due to the strong synergistic effect, which ensures long-term usability of photocatalyst and great promise in water purification. This work can offer valuable reference into designs and construction of Ce-based heterojunction photocatalysts for environmental remediation. | Yan Song Ran Wang Xiuyuan Li Baiqi Shao Hongpeng You Chaozheng He | 2022 | Chinese Chemical Letters2022，33，3： | 0 |
| 15 | Antimicrobial-free knitted fabric as wound dressing and the mechanism of promoting infected wound healing显示文摘Fibrous biomaterials are widely used in the design and fabrication of antibacterial wound dressings.Two strategies are used to make anti-infective dressings:antibacterial and probiotic therapies,which have potential biotoxicity and other side-effects.Herein,we report a new strategy for fabricating wound dressings to combat infection.Poly(4-methyl-1-pentene)(PMP) fabric can remove bacteria from infectious wounds through dressing changes based on its efficient bacterial adhesion.The maximum adhered count of S.aureus and E.coli on the PMP fabric was 1.63 × 106CFU/cm~2 and 4.77 × 105CFU/cm~2,respectively.In addition,the PMP fabric could inhibit the twitching motility of bacteria,which is beneficial for inhibiting infection.The ability of the PMP fabric to accelerate wound healing was demonstrated in vivo in a rat wound model.After treatment with the PMP fabric dressing,pathogenic bacteria in the wound were removed through dressing change;therefore,the wound exhibited better healing speed than when the commercial dressing was used.The low bacterial concentration effectively stimulated the expression of growth factors and suppressed wound inflammation,thereby accelerating wound healing.PMP fabric has three advantages:(1) it has been approved for use in clinical treatment by the Food and Drug Administration;(2) no antibacterial agent or probiotics were used;(3) the fabric could be manufactured through an industrial production process.These results indicate that the new strategy can be used in the design of new-generation wound dressings for antibacterial applications. | ZHANG Huan WAN HuaKun HU XiuYuan ZHAO QingHua LU JianGuo WANG Dong LU ZhenTan | 2023 | Science China(Technological Sciences)2023，66，7： | 0 |
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