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| 1 | Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation显示文摘许多干细胞人口被他们的本地微型环境(壁龛) 紧调整,它包括 stromal 房间的不同类型。然而,很少对壁龛亚群并列地由决定干细胞命运的机制被知道。这里,我们识别那 Yki,关键河马小径部件,为护卫房间(EC ) 是必要的在在果蝇卵巢支持 germline 区别的功能。我们发现那个刺猬(Hh ) 发信号首先从帽子房间发出,支持 EC 的功能肘脉 interruptus (Ci ) ,表明受动器的 Hh,禁止河马 kinase 的行为串联活动。机械学地,我们发现 Ci 竞争地与 Hpo 交往并且损害表明复杂形成的 Hpo-Wts,从而支持的 Yki 原子本地化。Ci 的行动保证发信号在 EC 反对 Sd/Tgi/Vg-mediated 缺省压抑的有效 Yki。这研究揭开解释壁龛房间的亚群怎么协调经由表明串音的 Hh 河马决定干细胞命运的机制,并且提高我们发信号的 oncogenic Yki/YAP 的机械学的规定的理解。 | Chaoyi Li Lijuan Kan Yan Chen Xiudeng Zheng Weini Li Wenxin Zhang Lei Cao Xiaohui Lin Shanming Ji Shoujun Huang Guoqiang Zhang Xiaohui Liu Yi Tao Shian Wu Dahua Chen | 2015 | Cell Research2015，25，10： | 5 |
| 2 | A Robust Authentication Scheme for Filtering of Injected False Data in Dynamic Wireless Sensor Networks显示文摘 | HU Yupeng LIN Yaping YU Jianping ZENG Weini YI Yeqing LI Xiaolong | 2007 | Chinese Journal of Electronics2007，16，3： | 4 |
| 3 | Multistatic ground-based differential interferometric MIMO radar for 3D deformation measurement显示文摘Deformation measurement is crucial for forecasting landslide hazards of natural and engineered slopes. Ground-based differential interferometric radar(GB-DInRad) uses phase differential interferometric technology for surface deformation measurements and offers the advantages of all-day, allweather, and noncontact measurements. | Cheng HU Yunkai DENG Weiniing TIAN | 2021 | Science China(Information Sciences)2021，64，12： | 3 |
| 4 | Hierarchical flower-like cobalt phosphosulfide derived from Prussian blue analogue as an efficient polysulfides adsorbent for long-life lithium-sulfur batteries显示文摘Lithium-sulfur (Li-S) battery as one of the most attractive candidates for energy storage systems has attracted extensive interests.Herein,for the first time,hierarchical flower-like cobalt phosphosulfide architectures (defined as 'CoSP') derived from Prussian blue analogue (PBA) was fabricated through the conversion of Co-based PBA in PxSy atmosphere.The as-prepared polar CoSP could effectively trap polysulfides through the formation of strong chemical bonds.In addition,after the combination of CoSP with high conductive rGO,the obtained CoSP/rGO as sulfur host material exhibits ultralow capacity decay rate of 0.046% per cycle over 900 cycles at a current density of 1 C.The excellent performance could be attributed to the shortened lithium diffusion pathways,fastened electron transport ability during polysulfide conversion,and increased much more anchor active sites to polysulfides,which is expected to be a promising material for Li-S batteries.It is believed that the as-prepared CoSP/rGO architectures will shed light on the development of novel promising materials for Li-S batteries with high cycle stability. | Xiaoxia Chen Xuyang Ding Haliya Muheiyati Zhenyu Feng Liqiang Xu Weini Ge Yitai Qian | 2019 | Nano Research2019，12，5： | 2 |
| 5 | An automated radiographic NDT system for weld inspection-Flaw detection显示文摘 | Warren T Jia Weini | 1998 | NDT & E international1998，31，3： | 1 |
| 6 | A Web-Based Environment for Virtual Laboratory with CORBA Technology显示文摘 | Wang Jianxin Lu Weini Jia Weijia | 2003 | International Journal of Computer Processing of Oriental Languages (S0219-4279)2003，16，4： | 1 |
| 7 | A Web-based Environment for Virtual Laboratory with CORBA Technology 显示文摘 | Jianxin Wang Weini Lu | 2003 | International Journal of Computer Processing of Oriental Languages2003，16，4： | 1 |
| 8 | A Web-Based Environment for Virtual Laboratory with CORBA Technology显示文摘 | Wang Jianxin Lu Weini Jia Weijia | 2003 | International Journal of Computer Processing of Oriental Languages2003，16，4： | 1 |
| 9 | Effect of carbon content on the microstructure and mechanical properties of (Ti, W, Ta, Mo)(C, N)-(Co, Ni) cermets 显示文摘 | Zackrisson J Rolander U WeinI G | 1999 | International Journal of Refractory Metals & Hard Materials1999，17，5： | 1 |
| 10 | A Web - Based Environment for Virtual Laboratory with CORBA Technology 显示文摘 | Wang Jianxin Lu Weini Jia Weijia | 2003 | International Journal of Computer Processing of Oriental Languages (S0219 - 4279)2003，16，4： | 1 |
| 11 | A Web-Based Environment for Virtual Laboratory with CORBA Technology 显示文摘 | Wang Jianxin Lu Weini Jia Weijia | 2003 | International Journal of Computer Processing of Oriental Languages (S0219-4279)2003，16，4： | 1 |
| 12 | Fixation probabilities of random mutants under frequency dependent selection显示文摘 | Weini Huang Arne Traulsen | 2009 | Journal of Theoretical Biology2009，，2： | 1 |
| 13 | Properties of Wood Plastic Composites Made of Recycled HDPE and Wood Flour from CCA-treated Wood Removed from Service显示文摘 | D Pascal Kamdem Haihong Jiang Weini Cui | 2004 | Composites2004，35，： | 1 |
| 14 | Evaluating regional mean optimal nitrogen rates in combination with indigenous nitrogen supply for rice production显示文摘 | Weini Wang Jianwei Lu Tao Ren Xiaokun Li Wei Su Mingxing Lu | 2012 | Field Crops Research2012，，： | 1 |
| 15 | Preparation and Pharmacodynamic Evaluation of Kang Zhu Gan Lu Oral Proliposome, a New Hypoglycemic Tibetan Medicine显示文摘[Objectives]To effectively solve the problem of poor oral bioavailability of total flavonoids in Kang Zhu Gan Lu(ZYZH),a new hypoglycemic Tibetan solid preparation,ZYZH oral proliposome was prepared by modern preparation method,and its hypoglycemic effect was evaluated.[Methods]ZYZH proliposome was prepared by carrier deposition method,and its particle morphology and Zeta potential were detected.Taking encapsulation efficacy as indictor,the optimal prescription and preparation process of ZYZH oral proliposome were screened by orthogonal experiment.In addition,the hypoglycemic activity of ZYZH oral liposome in alloxan-induced hyperglycemic mice was studied.[Results]The repose angle,average particle size,encapsulation efficiency,and Zeta potential of ZYZH proliposome are 34.2°,(442.5±3.5)nm,67.7%and(-47.2±3.4)mV,respectively.Compared with the model group,the fasting blood glucose level of the hyperglycemic mice significantly declined(P<0.01),and their body weight changed insignificantly after four weeks of oral administration of ZYZH proliposome(P>0.05).[Conclusions]The preparation process of ZYZH oral proliposome is characterized by simple operation,high encapsulation efficiency and good stability.The new hypoglycemic Tibetan drug ZYZH oral liposome has obvious hypoglycemic effect on alloxan-induced hyperglycemic mice. | Weini DAI Yu MAO Lingmin LIN Xinran MI | 2019 | Medicinal Plant2019，10，5： | 0 |
| 16 | Circadian clock control of MRTF/SRF pathway suppresses beige adipocyte thermogenic recruitment显示文摘The morphological transformation of adipogenic progenitors into mature adipocytes requires dissolution of actin cytoskeleton with loss of myocardin-related transcription factor(MRTF)/serum response factor(SRF)activity.Circadian clock confers temporal control in adipogenic differentiation,while the actin cytoskeleton–MRTF/SRF signaling transduces extracellular physical niche cues.Here,we define a novel circadian transcriptional control involved in actin cytoskeleton–MRTF/SRF signaling cascade that modulates beige fat thermogenic function.Key components of actin dynamic–MRTF/SRF pathway display circadian regulation in beige fat depot.The core clock regulator,brain and muscle arnt-like 1(Bmal1),exerts direct transcriptional control of genes within the actin dynamic–MRTF/SRF cascade that impacts actin cytoskeleton organization and SRF activity.Employing beige fat-selective gene-targeting models together with pharmacological rescues,we further demonstrate that Bmal1 inhibits beige adipogenesis and thermogenic capacity in vivo via the MRTF/SRF pathway.Selective ablation of Bmal1 induces beigeing with improved glucose homeostasis,whereas its targeted overexpression attenuates thermogenic induction resulting in obesity.Collectively,our findings identify the clock–MRTF/SRF regulatory axis as an inhibitory mechanism of beige fat thermogenic recruitment with significant contribution to systemic metabolic homeostasis. | Xuekai Xiong Weini Li Ruya Liu Pradip Saha Vijay Yechoor Ke Ma | 2022 | Journal of Molecular Cell Biology2022，14，12： | 0 |
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