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33篇 您的检索式:作者名="Weiran Zhang"
    题名 作者 年代 出处 被引量
1Encapsulating segment-like antimony nanorod in hollow carbon tube as long-lifespan,high-rate anodes for rechargeable K-ion batteries显示文摘K-ion battery (KIB) is a new-type energy storage device that possesses potential advantages of low-cost and abundant resource of potassium.To develop advanced electrode materials for accommodating the large size and high activity of potassium ion is of great interests.Herein,a segment-like antimony (Sb) nanorod encapsulated in hollow carbon tube electrode material (Sb@HCT) was prepared.Beneficial from the virtue of abundant nitrogen doping in carbon tube,one-dimensional and hollow structure advantages,Sb@HCT exhibits excellent potassium storage properties:in the case of potassium bis(fluorosulfonyl)imide (KFSI) electrolyte,Sb@HCT displays a reversible capacity of up to 453.4 mAh·g^-1 at a current density of 0.5 A·g^-1 and good rate performance (a capacity of 211.5 mAh·g^-1 could be achieved at an ultrahigh rate of 5 A·g^-1).Additionally,Sb@HCT demonstrates excellent long-cycle stability at a current density of 2 A·g^-1 over 120 cycles.Meanwhile,electrolyte optimization is an effective strategy for greatly improving electrochemical performance.Through ex-situ characterizations,we disclosed the potassiation of Sb anode is quite reversible and undergoes multistep processes,combining solid solution reaction and two-phase reaction.Wen Luo Feng Li Weiran Zhang Kang Han Jean-Jacques Gaumet Hans-Eckhardt Schaefer Liqiang Mai 2019Nano Research2019,12,5:18
2Autophagy inhibition enhances apigenin-induced apoptosis in human breast cancer cells显示文摘Apigenin (4',5,7-trihydroxyflavone) is a member of the flavone subclass of flavonoids present in fruits and vegetables. The involvement of autophagy in the apigenin-induced apoptotic death of human breast cancer cells was investigated. Cell proliferation and viability were assessed by 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) and clonogenic assays. Flow cytometry, fluorescent staining and Western blot analysis were employed to detect apoptosis and autophagy, and the role of autophagy was assessed using autophagy inhibitors. Apigenin dose- and time-dependently repressed the proliferation and clonogenic survival of the human breast cancer T47D and MDA-MB-231 cell lines. The death of T47D and MDA-MB-231 cells was due to apoptosis associated with increased levels of Caspase3, PARP cleavage and Bax/Bcl-2 ratios. The results from flow cytometry and fluorescent staining also verified the occurrence of apoptosis. In addition, the apigenin-treated cells exhibited autophagy, as characterized by the appearance of autophagosomes under fluorescence microscopy and the accumulation of acidic vesicular organelles (AVOs) by flow cytometry. Furthermore, the results of the Western blot analysis revealed that the level of LC3-II, the processed form of LC3-I, was increased. Treatment with the autophagy inhibitor, 3-methyladenine (3-MA), significantly enhanced the apoptosis induced by apigenin, which was accompanied by an increase in the level of PARP cleavage. Similar results were also confirmed by flow cytometry and fluorescence microscopy. These results indicate that apigenin has apoptosis-and autophagy-inducing effects in breast cancer cells. Autophagy plays a cyto-protective role in apigenin-induced apoptosis, and the combination of apigenin and an autophagy inhibitor may be a promising strategy for breast cancer control.Xuchen Cao Bowen Liu Wenfeng Cao Weiran Zhang Fei Zhang Hongmeng Zhao Ran Meng Lin Zhang Ruifang Niu Xishan Hao Bin Zhang 2013Chinese Journal of Cancer Research2013,25,2:12
3^(207)Pb/^(206)Pb Zircon Dating of the Huangtuling Hypersthene-Garnet-Biotite Gneiss from the Dabie Mountains, Luotian County, Hubei Province, China: New Evidence for Early Precambrian Evolution显示文摘The Huangtuling hypersthene-garnet-biotite gneiss at Luotian County, Hubei Provine, is a typicalgranulite-facies rock of the Dabie Group Complex in the Dabie orogenic belt. Investigations on the morphology andoccurrence of zircons and their internal structures shown in the thin sections lead to the recognition of three types ofzircons, which are in good agreement with the types identified on the basis of morphology, colour and external fea-tures from the related zircon concentrates. The observation of zircons in the rock reveals that part of type 1 zirconsshow signs of a double-layered structure. The interval part existed in the protolith prior to the granulite-facies meta-morphism. Type 2, the prismatic zircons which mainly occur in garnet and hypersthene are metamorphic minerals ofthe granulite-facies metamorphism. Type 3, the round multifaceted zircons in felsic minerals and biotite, are proba-bly attributed to a later geological event related to migmatization. The 207Pb/206Pb zircon dating by direct evaporationon (thermal evaporation ion mass spectrometer) yields ages ranging from 2814 Ma to 1992 Ma. The age discrepancyamong these different zircon types is conspicuous. The yellow-brown(type 1) zircons give ages of 2814±29 Ma to2527±6 Ma, the prismatic euhedral zircons (type 2), 2456±7 Ma to 2254±4 Ma, and the round multifaceted zircons(type 3), 1992±10 Ma. The results are geologically interpreted in consideration of the complicated behaviours of zir-cons during Precambrian geological evolution of the Dabie area. (1) If the protolith of the gneiss is a sedimentaryrock, then type 1 zircons are clastic ones and the ages 2814±29 Ma and 2811±27 Ma may reflect the minimum age ofthe rocks of its source region. also the first geological event in the area. Sedimentation of the protolith occurred be-tween 2814 Ma and 2527 Ma, probably close to 2814 Ma. If the protolith is a volcanic rock, then the formation age ofthe supracrustal rocks of the Dabie Group Complex is around 2814 Ma. The age 2456±7 Ma reflects the time whenthe granulite-facies metamorphism took place. The later migmatization event is dated at aboat 1992±10 Ma, and isprobably the latest early Precambrian event in the area. The present work provides geochronological evidence for the existence of the Dabie Archaean craton, whichhad probably experienced 3 or 4 geological events during its early Precambrian evolution.JIAN Ping YANG Weiran and ZHANG Zichao Institute of Geology,CAGS,26 Baiwanzhuang Rd, Beijing 100037 China University of Geosciences, Wuhan, Hubei 430074 Yichang Institute of Geology and Mineral Resources, CAGS, Yichang, Hubei 443003 1999Acta Geologica Sinica(English Edition)1999,73,1:12
4A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China显示文摘The coronavirus disease 2019(COVID-19)pandemic is a global crisis,and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses.This study aimed to assess COVID-19-related essential clinical resource demands in China,based on different scenarios involving COVID-19 spreads and interventions.We used a susceptible–exposed–infectious–hospitalized/isolated–removed(SEIHR)transmission dynamics model to estimate the number of COVID-19 infections and hospitalizations with corresponding essential healthcare resources needed.We found that,under strict non-pharmaceutical interventions(NPIs)or mass vaccination of the population,China would be able to contain community transmission and local outbreaks rapidly.However,under scenarios involving a low intensity of implemented NPIs and a small proportion of the population vaccinated,the use of a peacetime–wartime transition model would be needed for medical source stockpiles and preparations to ensure a normal functioning healthcare system.The implementation of COVID-19 vaccines and NPIs in different periods can influence the transmission of COVID-19 and subsequently affect the demand for clinical diagnosis and treatment.An increased proportion of asymptomatic infections in simulations will not reduce the demand for medical resources;however,attention must be paid to the increasing difficulty in containing COVID-19 transmission due to asymptomatic cases.This study provides evidence for emergency preparations and the adjustment of prevention and control strategies during the COVID-19 pandemic.It also provides guidance for essential healthcare investment and resource allocation.Ting Zhang Qing Wang Zhiwei Leng Yuan Yang Jin Yang Fangyuan Chen Mengmeng Jia Xingxing Zhang Weiran Qi Yunshao Xu Siya Chen Peixi Dai Libing Ma Luzhao Feng Weizhong Yang 2021Engineering2021,7,7:7
5Kinetic study of the gas-phase reaction of O3 with three unsaturated alcohols显示文摘Rate constants for the reactions of ozone with 1-octen-3-ol, 1-nonen-3-ol and 1-nonen-4-ol have been determined at 298 ± 1 K and atmospheric pressure for the first time. The experiments were performed in a 100-L FEP Teflon film bag using absolute rate method; the rate constants were(1.91 ± 0.19) × 10^(-17),(1.89 ± 0.20) × 10^(-17), and(0.83 ± 0.08) × 10^(-17)cm^3/(molecule·sec) for 1-octen-3-ol, 1-nonen-3-ol, and 1-nonen-4-ol, respectively. The rate constants have been compared with those of unsaturated alcohols structural homologs, and used to estimate the reaction reactivity. The electronegativity of carbon–carbon double bond was calculated by atomic charges analysis. The calculated results show that the electronic effect of the lone pair electrons of hydroxyl oxygen is the main cause of the difference in rate coefficient. According to the obtained rate constants, the atmospheric lifetimes of studied unsaturated alcohols were also estimated, which indicates that the reaction with ozone is an important loss pathway in the atmosphere, especially in polluted areas.Weiran Li Yi Chen Shengrui Tong Yucong Guo Yunhong Zhang Maofa Ge 2018Journal of Environmental Sciences2018,30,9:4
6Beach Morphology and Coastline Evolution in the Southern Bohai Strait显示文摘The beach studied in this paper spans a length of 51 km and is one of several long sandy beaches in the southern Bohai Strait. Due to the obstruction of islands in the northeast and the influence of the underwater topography, the wave environment in the offshore area is complex; beach types and sediment transport characteristics vary along different coasts. The coastlines extracted from six aerial photographs in different years were compared to demonstrate the evolving features. Seven typical beach profiles were selected to study the lateral beach variation characteristics. Continuous wind and wave observation data from Beihuangcheng ocean station during 2009 were employed for the hindcast of the local wave environment using a regional spectral wave model. Then the results of the wave hindcast were incorporated into the LITDRIFT model to compute the sediment transport rates and directions along the coasts and analyze the longshore sand movement. The results show that the coastline evolution of sand beaches in the southern Bohai Strait has spatial and temporal variations and the coast can be divided into four typical regions. Region(I), the north coast of Qimudao, is a slightly eroded and dissipative beach with a large sediment transport rate; Region(II), the southwest coast of Gangluan Port, is a slightly deposited and dissipative beach with moderate sediment transport rate; Region(III), in the central area, is a beach that is gradually transformed from a slightly eroded dissipative beach to a moderately or slightly strong eroded bar-trough beach from west to east with a relatively moderate sediment transport rate. Region(IV), on the east coast, is a strongly eroded and reflective beach with a weak sediment transport rate. The wave conditions exhibit an increasing trend from west to east in the offshore area. The distribution of the wave-induced current inside the wave breaking region and the littoral sediment transport in the nearshore region exhibit a gradual weakening tendency from west to east, which is opposite to the trend of the wave conditions outside the breaking region. The presence of submerged shoal(Dengzhou Shoal), deep trough(Dengzhou Channel), islands and irregular topography influnces the wave climate, beach types, wave-induced current features, littoral sediment transport trends and coastline evolution patterns in the southern Bohai Strait. Human activities, such as the sand exploitation of Dengzhou Shoal and other coastal engineering projects, also influence the beach morphology and coastline evolution.ZHANG Wei WU Jianzheng LI Weiran ZHU Longhai HU Rijun JIANG shenghui SUN Yonggen WANG Huijuan 2015Journal of Ocean University of China2015,14,5:3
7DNA methylation profile is associated with the osteogenic potential of three distinct human odontogenic stem cells显示文摘Among the various sources of human autologous stem cells,stem cells isolated from dental tissues exhibit excellent properties in tissue engineering and regenerative medicine.However,the distinct potential of these odontogenic cell lines remains unclear.In this study,we analyzed DNA methylation patterns to determine whether specific differences existed among three different odontogenic cell types.Using the HumanMethylation450 Beadchip,the whole genomes of human dental pulp stem cells(DPSCs),periodontal ligament stem cells(PDLSCs),and dental follicle progenitor cells(DFPCs)were compared.Then,the osteogenic potential of these cells was evaluated both in vitro and in vivo,and the methylation levels of certain genes related to bone formation differed among the three cell lines.P values less than 0.05 were considered to indicate statistical significance.The three cell types showed highly similar DNA methylation patterns,although specific differences were identified.Gene ontology analysis revealed that one of the most significantly different gene categories was related to bone formation.Thus,expression of cell surface epitopes and osteogenic-related transcription factors as well as the bone formation capacity were compared.The results showed that compared with DFPCs and DPSCs,PDLSCs had higher transcription levels of osteogenic-related factors,a higher in vitro osteogenic potential,and an increased new bone formation capacity in vivo.In conclusion,the results of this study suggested that the differential DNA methylation profiles could be related to the osteogenic potential of these human odontogenic cell populations.Additionally,the increased osteogenic potential of PDLSCs might aid researchers or clinicians in making better choices regarding tissue regeneration and clinical therapies.Tingting Ai Jieni Zhang Xuedong Wang Xiaowen Zheng Xueyan Qin Qian Zhang Weiran Li Wei Hu Jiuxiang Lin Feng Chen 2018Signal Transduction and Targeted Therapy2018,3,1:3
8The study on three-dimensional numerical model and fronts of the Jiulong Estuary and the Xiamen Bay显示文摘Applying the methods of on-site observation and dynamic model, the research on the fronts at the Jiulong Estuary has been carried out, during which spatial and temporal distribution, dynamic characteristics and formation mechanism of salinity fronts are analyzed and discussed. The research shows that the estuarine fronts mainly lie in the area from the Jiyu Islet to the Haimen Island, outside of Yuweizai to Hulishan cross-section, the near coast of Yuweizai and the south of the Songyu-Gulangyu Channel. The fronts in the former two regions are formed directly by plume, while the one near the coast of Yuweizai is a tidal intrusion front caused by flood current and the one at the south of the Songyu-Gulangyu Channel is the result of current shear transformation. Under normal circumstances, fresh water of the Jiulong River mainly influences the inside of the Xiamen Bay, and when it is in typhoon seasons, plume front can affect the Taiwan Strait and has an effect on the biogeochemical processes in the strait.LUO Zhibin PAN Weiran LI Li ZHANG Guorong 2012Acta Oceanologica Sinica2012,31,4:3
9Intra-abdominal aortic balloon occlusion in the management of placenta percreta显示文摘Background:Massive bleeding is the main concern for the management of placenta percreta(PP).Intra-abdominal aortic balloon occlusion(IABO)is one method for pelvic devascularization,but the efficacy of IABO is uncertain.This study aims to investigate the outcomes of IABO in PP patients.Methods:We retrospectively reviewed the clinical data of PP cases from six tertiary centers in China between January 2011 and December 2015.PP cases with/without the use of IABO were analyzed.Propensity score matching analysis was performed to reduce the effect of selection bias.Postpartum hemorrhage(PPH)and the rate of hysterectomy,as well as neonatal outcomes,were analyzed.Results:One hundred and thirty-two matched pairs of patients were included in the final analysis.Compared with the control group,maternal outcomes,including PPH(68.9%vs.87.9%,χ^(2)=13.984,P<0.001),hysterectomy(8.3%vs.65.2%,χ^(2)=91.672,P<0.001),and repeated surgery(1.5%vs.12.1%,χ^(2)=11.686,P=0.001)were significantly reduced in the IABO group.For neonatal outcomes,Apgar scores at 1 minute(8.67±1.79vs.8.53±1.68,t=-0.638,P=0.947)and 5 minutes(9.43±1.55vs.9.53±1.26,t=0.566,P=0.293)were not significantly different between the two groups.Conclusions:IABO can significantly reduce blood loss,hysterectomies,and repeated surgeries.This procedure has not shown harmful effects on neonatal outcomes.Weiran Zheng Ruochong Dou Jie Yan Xinrui Yang Xianlan Zhao Dunjin Chen Yuyan Ma Weishe Zhang Yiling Ding Ling Fan Huixia Yang 2022Chinese Medical Journal2022,,4:2
10Fabrication of lithium silicates from zeolite for CO2 capture at high temperatures显示文摘Li4Si O4 has been regarded as one of the most promising high-temperature CO2 sorbents.However,for practical applications,its CO2sorption kinetics,cycling stability and sorption properties at lower temperatures or lower CO2 concentrations have to be improved.In this contribution,four Li4Si O4 sorbents were synthesized from zeolite precursors MCM-41,MCM-48,TS-1,and ZSM-5.The CO2 uptake,cycling stability and the optimal CO2 sorption conditions were investigated.Among the samples,MCM-41-Li4Si O4 showed the best cycling stability at 650°C,with a stable reversible CO2 uptake of 29.1 wt%under 100 vol%CO2 during 20 cycles.But its sorption kinetics and CO2 uptakes at lower temperatures and lower CO2 concentrations need to be improved.We then demonstrated that the sorption kinetics can be improved by modifying the MCM-41 precursor with metals such as Al,Ti,Ca,and Na.The Na-MCM-41-Li4Si O4 sample exhibited the highest sorption rate,and reached the equilibrium sorption capacity close to the theoretical value of 36.7 wt%within 20 min.In addition,we proved that coating the MCM-41-Li4Si O4with Na2CO3and K2CO3can significantly increase the CO2uptakes at lower temperatures(e.g.550℃)and lower CO2concentrations(10–20 vol%).At 550℃ and under 20 vol%CO2,15 wt%K2CO3-MCM-41-Li4Si O4 and 10 wt%Na2CO3-MCM-41-Li4Si O4 sorbents resulted in a CO2 uptake of 32.2 wt%and 34.7 wt%,respectively,which are much higher than that of MCM-41-Li4Si O4(11.8 wt%).These two sorbents also showed good cycling stability.The promoiting mechasnim by alkali carbonate coating was discussed by a doubleshell model.Yu Zhang Yanshan Gao Benoit Louis Qiang Wang Weiran Lin 2019Journal of Energy Chemistry2019,28,6:2
11Personality Openness Predicts Driver Trust in Automated Driving显示文摘Maintaining an appropriate level of trust in automated driving(AD)is critical to safe driving.However,few studies have explored factors affecting trust in AD in general,and no study,as far as is known,has directly investigated whether driver personality influences driver trust in an AD system.The current study investigates the relation between driver personality and driver trust in AD,focusing on Level 2 AD.Participants were required to perform a period of AD in a driving simulator,during which their gaze and driving behavior were recorded,as well as their subjective trust scores after driving.In three distinct measures,a significant correlation between Openness and driver trust in the AD system is found:participants with higher Openness traits tend to have less trust in the AD system.No significant correlations between driver trust in AD and other personality traits are found.The findings suggest that driver personality has an impact on driver trust in AD.Theoretical and practical implications of this finding are discussed.Wenmin Li Nailang Yao Yanwei Shi Weiran Nie Yuhai Zhang Xiangrong Li Jiawen Liang Fang Chen Zaifeng Gao 2020Automotive Innovation2020,3,1:2
12Atmospheric oxidizing capacity in autumn Beijing:Analysis of the O_(3) and PM_(2.5) episodes based on observation-based model显示文摘Atmospheric oxidizing capacity(AOC)is the fundamental driving factors of chemistry process(e.g.,the formation of ozone(O_(3))and secondary organic aerosols(SOA))in the troposphere.However,accurate quantification of AOC still remains uncertainty.In this study,a comprehensive field campaign was conducted during autumn 2019 in downtown of Beijing,where O_(3) and PM_(2.5) episodes had been experienced successively.The observation-based model(OBM)is used to quantify the AOC at O_(3) and PM_(2.5) episodes.The strong intensity of AOC is found at O_(3) and PM2.5 episodes,and hydroxyl radical(OH)is the dominating daytime oxidant for both episodes.The photolysis of O_(3) is main source of OH at O_(3) episode;the photolysis of nitrous acid(HONO)and formaldehyde(HCHO)plays important role in OH formation at PM_(2.5) episode.The radicals loss routines vary according to precursor pollutants,resulting in different types of air pollution.O_(3) budgets and sensitivity analysis indicates that O_(3) production is transition regime(both VOC and NOx-limited)at O3 episode.The heterogeneous reaction of hydroperoxy radicals(HO_(2))on aerosol surfaces has significant influence on OH and O_(3) production rates.The HO_(2) uptake coefficient(γHO_(2))is the determining factor and required accurate measurement in real atmospheric environment.Our findings could provide the important bases for coordinated control of PM_(2.5) and O_(3) pollution.Chenhui Jia Shengrui Tong Xinran Zhang Fangjie Li Wenqian Zhang Weiran Li ZhenWang Gen Zhang Guiqian Tang Zirui Liu Maofa Ge 2023Journal of Environmental Sciences2023,,2:2
13A single-molecule multicolor electrochromic device generated through medium engineering显示文摘Multicolor organic electrochromic materials are important for the generation of full-color devices.However,achieving multiple colors using a single-molecule material has proved challenging.In this study,a multicolor electrochromic prototype device is generated by integrating medium engineering/in situ‘electro base’/laminated electrode technologies with the simple flying fish-shaped methyl ketone TM1.This multicolor electrochromic(green,blue and magenta)device is durable and has a high coloration efficiency(350 cm^(2) C^(-1)),a fast switching time(50 ms)and superior reversibility.This study is a successful attempt to integrate solvatochromism and basochromism in an electronic display.This integration not only introduces a new avenue for color tuning,in addition to the structural design of the colorant,but will also inspire further developments in the tuning of many other properties by this medium engineering approach,such as conductance and the redox property,and thereby accelerate versatile applications in data recording,ultrathin flexible displays,and optical communication and sensing.Yu-Mo Zhang Xiaojun Wang Weiran Zhang Wen Li Xiaofeng Fang Bing Yang Minjie Li Sean Xiao-An Zhang 2015Light(Science & Applications)2015,4,1:2
14Angiotensin Ⅱ type Ⅰ receptor agonistic autoantibody-induced apoptosis in neonatal rat cardiomyocytes is dependent on the generation of tumor necrosis factor-α显示文摘血管收缩素 II 类型我受体论战的自身抗体(AT1-AA ) 与子间前和高血压有关并且有在胎盘刺激肿瘤坏死 factor-alpha (TNF-) 的生产的直接效果。TNF- 是 apoptosis 的一个已知的调停人。然而,很少研究在 cardiomyocytes 的 AT1-AA-induced apoptosis 以内报导了 TNF- 和它的关系的角色。在这研究,新生的老鼠 cardiomyocytes 与 AT1-AA 的各种各样的集中被对待。新生的老鼠 cardiomyocytes 的 apoptosis 是坚定的使用 TUNEL 试金和流动 cytometry。分泌 TNF- 的水平被连接酶的 immunosorbent 试金测量,并且 caspase-3 活动被一个 fluorogenic 朊酶试金工具包测量。AT1 受体封锁和 TNF 禁止者被增加决定他们是否能禁止 AT1-AA 的 apoptotic 效果。结果证明 AT1-AA 在一个剂量依赖者和时间依赖者举止导致了新生的老鼠 cardiomyocytes 的 apoptosis。AT1-AA 增加了 TNF 分泌物和 caspase-3 活动。AT1 受体封锁完全废除了 AT1-AA-induced TNF- 分泌物, caspase-3 激活,和 cardiomyocyte apoptosis。TNF- 受体禁止者显著地稀释的 AT1-AA-induced 新生的老鼠 cardiomyocyte apoptosis。在 pre 惊厥的病人的血浆的 AT1-AA 通过表明小径的 TNF-caspase 支持了新生的老鼠 cardiomyocyte apoptosis。Weiran Chai Wenhui Zhang Zhu Jin Yiping Feng Yanping Kuang Jianming Zhi 2012Acta Biochimica et Biophysica Sinica2012,44,12:1
15Enrichment of heavy metals in the inner shelf mud of the East China Sea and its indication to human activity显示文摘Bin Chen Dejiang Fan Weiran Li Liang Wang Xilin Zhang Ming Liu Zhigang Guo 2014Continental Shelf Research2014,,:1
16Notes on a meromorphic function sharingone small function with its derivative 显示文摘Zhang Tongdui Lti Weiran 2008Complex Variables and Elliptic Equations2008,53,9:1
17Uniqueness theorems on meromorphic functions sharing one value 显示文摘ZHANG Tongdui LU Weiran 2008Comput Math Appl2008,55,:1
18The Application of Ecosystem Dynamic Model in Xiamen Bay显示文摘Jun Wang Zhibin Luo Weiran Pan Guorong Zhang 2013Journal of Earth Science and Engineering2013,3,4:1
19Characteristics of Sludge from Sewage Discharge Channels of Tianjin, China显示文摘Chaosheng Zhang Lijun Wang Weiran Shen Wenju Zhang 2002Water Air and Soil Pollution (-)2002,,1:1
20Gender difference in network relationship between inter-temporal decisions and prefrontal activation levels in internet gaming disorder显示文摘Background:Impulsivity and decision-making are key factors in addiction.However,little is known about how gender and time sensitivity affect impulsivity in internet gaming disorder(IGD).Objective:To investigate the gender difference of impulsive decision-making and relevant brain responses in IGD.Methods:We conducted a functional magnetic resonance imaging(fMRI)study with 123 participants,including 59 IGD individuals(26 females)and 64 matched recreational game users(RGUs,23 females).Participants performed a delay-discounting task during fMRI scanning.We examined gender-by-group effects on behavioral and neural measures to explore the preference for immediate over delayed rewards and the associated brain activity.We also investigated the network correlations between addiction severity and behavioral and neural measures,and analyzed the mediating role of brain activity in the link between delay discounting parameters and IGD severity.Results:We found significant gender-by-group interactions.The imaging results revealed gender-by-group interactions in the dor-solateral prefrontal cortex,medial frontal gyrus,and inferior frontal gyrus(IFG).Post hoc analysis indicated that,for females,RGUs showed higher activity than IGD individuals in these brain regions,while for males IGD individuals exhibited higher activity than RGUs.The activation in the left IFG mediated the relation between Internet Addiction Test score and discount rate in females.In males,the activation in the right dlPFC mediated the relation between IAT score and time sensitivity.Discussion:Our findings imply that male IGD participants demonstrate impaired intertemporal decisions associated with neural dysfunction.Influencing factors for impulsive decision-making in IGD diverge between males(time sensitivity)and females(discount rate).These findings augment our comprehension of the neural underpinnings of gender differences in IGD and bear significant implications for devising effective intervention strategies for treating people with IGD.Hui Zheng Weiran Zhou Min Wang Hao-hao Dong Chunlei Lu Jia-lin Zhang Xue-feng Ma Yanbo Hu Guang-Heng Dong 2023Psychoradiology2023,3,1:0
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