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| 1 | Multidimensional CdS nanowire/CdIn2S4 nanosheet heterostructure for photocatalytic and photoelectrochemical applications显示文摘Nanomaterial 形状能在材料性质上有深刻效果,因此提供一个有效方法改进设计材料和设备的表演。象一个那样的多维的体系结构的合理制造维(1D ) 二维(2D ) 混合 nanomaterials 能集成单个部件的优点并且提供提高的功能。然而,因为 nanostructures 的不同生长机制,它仍然很正在质问制作 1D/2D 体系结构。这里,我们在场一新调停溶剂,出现为 CdS nanowire (NW ) 的合成的反应驱动的生长线路 /CdIn 2 S 4 nanosheet (NS ) 1D/2D 体系结构。同样获得的 CdS NW/CdIn 2 S 4 NS 结构为比单个部件切开的水展出高得多的 visible-light-responsive photocatalytic 活动。CdS NW/CdIn 2 S 4 NS heterostructure 进一步被制作进 photoelectrodes,哪个完成了 2.85 妈癩的可观的光电流密度?? | Ting Wang Yuanyuan Chai Dekun Ma Wei Chen Weiwei Zheng Shaoming Huang | 2017 | Nano Research2017，10，8： | 7 |
| 2 | Cosensitization process effect of D-A-π-A featured dyes on photovoltaic performances显示文摘Cosensitization based on two or multiple dyes as 'dye cocktails' can hit the target on compensating and broadening light-harvesting region.Two indoline D-A-π-A motif sensitizers(WS-2 and WS-39) that possess similar light response area but distinctly reversed feature in photovoltaic performance are selected as the specific cosensitization couple. That is, WS-2 shows quite high photocurrent but low photovoltage, and WS-39 gives relatively low photocurrent but quite high photo voltage. Due to the obvious 'barrel effect',both dyes show medium PCE around8.50%. In contrast with the previous cosensitization strategy mostly focused on the compensation of light response region, herein we perform different cosensitization sequence, for taking insight into the balance of photocurrent and photo voltage, and achieving the synergistic improvement in power conversion efficiency(PCE). Electronic impedance spectra(EIS) indicate that exploiting dye WS-39 with high V_(OC) value as the primary sensitizer can repress the charge recombination more effectively, resulting in superior V_(OC) rather than using dye WS-2 with high J_(SC)as the primary sensitizer. As a consequence, a high PCE value of 9.48% is obtained with the delicate cosensitization using WS-39 as primary dye and WS-2 as accessory dye, which is higher than the corresponding devices sensitized by each individual dye(around 8.48-8.67%). It provides an effective optimizing strategy of cosensitization how to combine the individual dye advantages for developing highly efficient solar cells. | Bo Liu Qipeng Chai Weiwei Zhang Wenjun Wu He Tian Wei-Hong Zhu | 2016 | Green Energy & Environment2016，1，1： | 1 |
| 3 | PtHAK5, a candidate for mediating high-affinity K^+ uptake in the halophytic grass, Puccinellia tenuiflora显示文摘Puccinellia tenuiflora is a typical salt-excluding halophytic grass with strong salt-tolerance, which enhances tolerance by restricting Na^+influx as well as having a strong selectivity for K^+ over Na^+. The HAK5 K^+ transporters generally modulate effective K^+acquisition in plants, especially under low K^+ condition. In this study,Pt HAK5 from P. tenuiflora was isolated by RT-PCR and characterized using yeast complementation. The results showed Pt HAK5 consisted of 784 amino acids and shared over 80% homology with the identified high-affinity K^+ transporter HAK5 from other higher plants. The expression of PtHAK5 rescued the K^+ -uptake-defective phenotype of yeast strain CY162. In conclusion, PtHAK5 is a candidate for mediating high-affinity K^+ uptake under low K^+ conditions. | Haili YANG Weidan ZHANG Weiwei CHAI Wenying WANG Li GAO Jing ZHANG Yongping WANG Suo-Min WANG | 2018 | Frontiers of Agricultural Science and Engineering2018，5，1： | 1 |
| 4 | Zuogui Wan(左归丸) improves trabecular bone microarchitecture in ovariectomy-induced osteoporosis rats by regulating orexin-A and orexin receptors显示文摘OBJECTIVE:To investigate the protective effects of Zuogui Wan(左归丸,ZGW)on bone loss induced by ovariectomy(OVX)and its mechanism via orexin-A and orexin receptors in the osteoporosis rat model.METHODS:Fifty Sprague-Dawley female rats were randomly divided into sham-operated(sham)group and four OVX subgroups.Rats subjected to sham and OVX were treated with the vehicle(OVX,1 mL/100 g weight,n=10),17β-estradiol(E2,50μg·kg-1·d-1),and ZGW at the doses of 2.3(ZGW-L)and 4.6(ZGW-H)g/kg/day lyophilized powder daily for 3 months,respectively.The serum biochemical parameters of 17β-estrogen(17β-E2),tartrate-resistant acid phosphatase(TRACP-5 b)and bone alkaline phosphatase(BALP)were measured by enzyme-linked immunosorbent assay.Hematoxylin-eosin staining was used to detect the changes in the morphological structure in bones.Microcomputed tomography was used to evaluate the bone mineral density and microarchitecture of the distal femur.The gene or protein expression of orexin-A,orexin receptor 1(OX1R),orexin receptor 2(OX2R),osteoprotegerin(OPG)and receptor activator of nuclear factor-κB ligand(RANKL)were assayed by either quantitative polymerase chain reaction or Western blot analysis.RESULTS:Compared with the OVX group,ZGW could reduce the serum level of TRACP-5b and increased the serum levels of BALP and 17β-E2(P<0.01).Meanwhile,ZGW could prevent bone loss and improved bone trabecular microarchitecture by increasing the trabeculae structure thickness and trabecular number,and arranging the trabeculae structure properly.Compared with the OVX group,it was upregulated for the orexin-A and OX2R mRNA or protein expression from the hypothalamus and tibiae,and OPG in the tibiae of ZGW groups(P<0.01,<0.05),while downregulated for the OX1R mRNA and protein expression in the tibiae and hypothalamus and RANKL from the tibiae(P<0.01).CONCLUSION:ZGW exhibited a protective effect for PMOP that may be mediated via orexin-A and orexin receptors regulation. | LIU Feixiang TAN Feng FAN Qiaoling TONG Weiwei TENG Zhanli YE Sumin LI Xing ZHANG Mingyue CHAI Yi MAI Chongying | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 0 |
| 5 | A Detection Method of Bolts on Axlebox Cover Based on Cascade Deep Convolutional Neural Network显示文摘This paper proposes a cascade deep convolutional neural network to address the loosening detection problem of bolts on axlebox covers.Firstly,an SSD network based on ResNet50 and CBAM module by improving bolt image features is proposed for locating bolts on axlebox covers.And then,theA2-PFN is proposed according to the slender features of the marker lines for extracting more accurate marker lines regions of the bolts.Finally,a rectangular approximationmethod is proposed to regularize themarker line regions asaway tocalculate the angle of themarker line and plot all the angle values into an angle table,according to which the criteria of the angle table can determine whether the bolt with the marker line is in danger of loosening.Meanwhile,our improved algorithm is compared with the pre-improved algorithmin the object localization stage.The results show that our proposed method has a significant improvement in both detection accuracy and detection speed,where ourmAP(IoU=0.75)reaches 0.77 and fps reaches 16.6.And in the saliency detection stage,after qualitative comparison and quantitative comparison,our method significantly outperforms other state-of-the-art methods,where our MAE reaches 0.092,F-measure reaches 0.948 and AUC reaches 0.943.Ultimately,according to the angle table,out of 676 bolt samples,a total of 60 bolts are loose,69 bolts are at risk of loosening,and 547 bolts are tightened. | Ji Wang Liming Li Shubin Zheng Shuguang Zhao Xiaodong Chai Lele Peng Weiwei Qi Qianqian Tong | 2023 | Computer Modeling in Engineering & Sciences2023，，3： | 0 |
| 6 | Electrophilic Halogen Reagents-mediated Halogenation: Synthesis of Halogenated Dihydro-1,3-oxazine Derivatives显示文摘Halogenation of N-cinnamylbenzamides and N-[(2H-chromen-3-yl)methyl]benzamides using electrophilic halogen source was reported.Various halogenated dihydro-1,3-oxazine derivatives(45 examples)were synthesized in high to excellent yields(up to 98%yields),as well as halogenated dihydrochromeno-1,3-oxazine derivatives(56 examples,up to 96%yields).The properties of mild conditions,metal-free and high efficiency of the reaction made it a promising strategy in future applications for the construction of carbon-halogen(fluorine,F;chlorine,Cl;bromine,Br;iodine,I)bond and 1,3-oxazine derivatives. | QI Liang QIN Yuji WANG Xueqing CHAI Hongli ZHU Weiwei ZHOU Yifeng | 2023 | Chemical Research in Chinese Universities2023，39，6： | 0 |
| 7 | Functional Analysis of Dunaliella salina Calmodulin Kinase Gene显示文摘[Objectives] This study was conducted to investigate the function of Dunaliella salina calmodulin kinase(CaM K) gene.[Methods] The sense and antisense gene fragments(223 bp) and spacer sequence(129 bp) of D.salina calmodulin kinase gene were cloned and inserted into the downstream part of the35 S promoter of the eukaryotic expression vector pM DCMGN-Cat.The siRNA expression system of CaM K gene was successfully constructed.The p CaM K-RNAi expression vector was transformed into D.salina cells by the LiA c/PEG-mediated method,giving transgenic D.salina.The expression of CaM K gene was then analyzed by real-time fluorescence quantitative PCR.[Results]The expression of CaM K gene in the transgenic D.salina was significantly reduced,by 70% compared with the control group,suggesting that the expression of CaM K gene was significantly inhibited.The examination of the growth status of D.salina showed that D.salina cell division and proliferation were also affected.It is proved that CaM K gene has a positive regulation effect on the division and proliferation of D.salina cells.[Conclusions] The study provides important information for further elucidating the function and action mechanism of D.salina calmodulin kinase gene. | Zhenyu XING Mingfang WANG Xiangnan GAO Weiwei XU Yuting CONG Xiaojie CHAI | 2020 | Agricultural Biotechnology2020，9，2： | 0 |
| 8 | Semaphorin 7A promotes human vascular smooth muscle cell proliferation and migration through theβ-catenin signaling pathway显示文摘Background:Vascular smooth muscle cells(VSMCs)undergo a conversion from a contractile phenotype to a proliferative synthetic phenotype,contributing to the pathogenesis of cardiovascular diseases.Semaphorin 7A(SEMA7A)is a glycosylphosphatidylinositol-anchored membrane protein that plays an important role in vascular homeostasis by regulating endothelial cell behaviors.However,the expression and role of SEMA7A in VSMCs remain unclear.Methods:In this study,we screened for VSMC-regulating genes in publicly available datasets and analyzed the expression of SEMA7A in human coronary artery smooth muscle cells(hCASMCs)treated with platelet-derived growth factor-BB(PDGF-BB).The effects of SEMA7A overexpression and knockdown on hCASMC proliferation and migration were examined.The signaling pathways involved in the action of SEMA7A in hCASMCs were determined.Results:Bioinformatic analysis showed that SEMA7A was significantly dysregulated in VSMCs treated with oxidized low-density lipoprotein or overexpressing progerin,a pro-atherogenic gene.The PDGF-BB stimulation led to a concentration-and time-dependent induction of SEMA7A.Depletion of SEMA7A attenuated PDGF-BB-induced hCASMC proliferation and migration.Conversely,overexpression of SEMA7A enhanced hCASMC proliferation and migration.Mechanistically,SEMA7A stimulated the activation of theβ-catenin pathway and upregulated c-Myc,CCND1,and MMP7.Knockdown ofβ-catenin impaired SEMA7A-induced hCASMC proliferation and migration.Conclusions:SEMA7A triggers phenotype switching in VSMCs through theβ-catenin signaling pathway and may serve as a potential therapeutic target for cardiovascular diseases. | XIAOSU SONG FEN GAO HONG LI WEIWEI QIN CHANJUAN CHAI GUOJUAN SHI HUIYU YANG | 2023 | BIOCELL2023，47，4： | 0 |
| 9 | Si-rhodamine based water-soluble fluorescent probe for bioimaging of Cu^(+)显示文摘A Si-substituted rhodamine based water-soluble fluorescent probe bearing a tetrathia-azacrown was designed for fluorescence imaging of Cu^(+) with substantial affinity and selectivity.In physiological condition,the developed probe with outstanding water-solubility exhibits ultrahigh sensitivity to Cu^(+),ensuring the reliable fluorescence imaging in vivo. | Xiaoyun Chai Weiwei Zhu Qingguo Meng Ting Wang | 2021 | Chinese Chemical Letters2021，32，1： | 0 |
| 10 | Regenerative antibacterial hydrogels from medicinal molecule for diabetic wound repair显示文摘Hydrogel products for chronic diabetic wounds,a serious and prevalent complication of diabetes,show limited effects on disability and remain nonspecific.Thus,improvements in the usage of pharmaceutical molecule in the hydrogels are highly desirable to increase the therapeutic effect of hydrogels.In this study,thioctic acid(a common medicine molecule in diabetes treatment)is used for preparing regenerative antibacterial hydrogels(RAH)which contains in situ synthesized silver nanoparticles(AgNPs).The RAH shows regenerative,self-healing and injectable ability,because of the reversible hydrogen and coordination bonds.With good regenerative capacity,RAH can be stored as powder to avoid the water loss and facilitate storage availability.Owing to the antioxidant properties of thioctic acid,the RAH can decrease the oxidative damage and retain cell proliferation efficiency.Due to the in situ synthesized AgNPs,the RAH also exhibits extraordinary antimicrobial capacities against MDR bacteria.All of these superiorities enable RAH to be a promising therapy for chronic diabetic wounds. | Chunxiao Chai Pengfei Zhang Lin Ma Qi Fan Zhicheng Liu Xiang Cheng Yunpeng Zhao Weiwei Li Jingcheng Hao | 2023 | Bioactive Materials2023，，7： | 0 |
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