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| 1 | 非维生素K拮抗与维生素K拮抗口服抗凝剂与脑出血患者住院死亡之间的关系显示文摘尽管非维生素K拮抗口服抗凝剂(non-vitamin K antagonist oral anticoagulants, NOACs)越来越多地应用于预防血栓栓塞性疾病,但关于NOACs相关性脑出血的数据仍然有限。 | 刘青 叶鹏 Inohara T Xian Y Liang L Matsouaka RA Saver JL Smith EE Schwamm LH Reeves MJ Hernandez AF Bhatt DL Peterson ED Fonarow GC | 2018 | 中华高血压杂志2018，26，2： | 16 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | Emergency medical services use and its association with acute ischaemic stroke evaluation and treatment in Singapore显示文摘Background Emergency medical services(EMS)is a critical link in the chain of stroke survival.We aimed to assess EMS use for stroke in Singapore,identify characteristics associated with EMS use and the association of EMS use with stroke evaluation and treatment.Methods The Singapore Stroke Registry combines nationwide EMS and public hospital data for stroke cases in Singapore.Multivariate regressions with the generalised estimating equations were performed to examine the association between EMS use and timely stroke evaluation and treatment.results Of 3555 acute ischaemic patients with symptom onset within 24 hours admitted to all five public hospitals between 2015 and 2016,68%arrived via EMS.Patients who used EMS were older,were less likely to be female,had higher stroke severity by National Institute of Health Stroke Scale and had a higher prevalence of atrial fibrillation or peripheral arterial disease.Patients transported by EMS were more likely to receive rapid evaluation(door-to imaging time≤25 min 34.3%vs 11.1%,OR=2.74(95%CI 1.40 to 5.38))and were more likely to receive intravenous tissue plasminogen activator(tPA,22.8%vs 4.6%,OR=4.61(95%CI 3.52 to 6.03)).Among patients treated with tPA,patients who arrived via EMS were more likely to receive timely treatment than self-transported patients(door-to needle time≤60 min 52.6%vs 29.4%,OR=2.58(95%CI 1.35 to 4.92)).Conclusions EMS use is associated with timely stroke evaluation and treatment in Singapore.Seamless EMS-Hospital stroke pathways and targeted public campaigns to advocate for appropriate EMS use have the potential to improve acute stroke care. | Hanzhang Xu Ying Xian Fung Peng Woon Janet Prvu Bettger Daniel T Laskowitz Yih Yng Ng Marcus Eng Hock Ong David Bruce Matchar Deidre Anne De Silva | 2020 | Stroke & Vascular Neurology2020，5，2： | 2 |
| 4 | LDL-C levels,lipid-lowering treatment and recurrent stroke in minor ischaemic stroke or TIA显示文摘Background and purpose Dyslipidaemia is a major risk factor for ischaemic stroke and transient ischaemic attack(TIA).This study aimed to investigate the association between baseline low-density lipoprotein cholesterol(LDL-C)level,lipid-lowering treatment and short-term risk of new stroke in patients with a minor ischaemic stroke or TIA.Methods We derived data from the Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events trial.Patients with a minor stroke or TIA were categorised by LDL-C level at baseline(<2.6 or≥2.6 mmol/L(100 mg/dL))and with or without lipid-lowering treatment after symptom onset.The primary outcome was a new ischaemic stroke at 3 months.The association of baseline LDL-C level,lowering treatment and outcomes were assessed.Results Among 3027 patients,2154(71.2%)patients had an initial LDL-C≥2.6 mmol/L,of which 1267(41.9%)received lipid-lowering treatment.Elevated LDL-C level was associated with a higher risk of new ischaemic stroke at 3 months in patients without lipid-lowering treatment(adj.HR=1.35,95%CI:1.19 to 1.53),but not in those with lipid-lowering treatment(adj.HR=0.99,95%CI:0.82 to 1.19)(p for interaction=0.007).Patients with LDL-C≥2.6 mmol/L had a numerically higher risk of ischaemic stroke(11.8%vs 8.0%,adj.HR=1.37,95%CI:0.96 to 1.96)in those without lipid-lowering treatment.For patients with LDL-C≥2.6 mmol/L,lipid-lowering treatment was associated with reduced risk of ischaemic stroke at 3 months(7.9%vs 11.8%;adj.HR=0.54,95%CI:0.39 to 0.75).Conclusions Elevated untreated baseline LDL-C level was associated with an increased short-term risk of ischaemic stroke among patients presenting with minor ischaemic stroke or TIA.There was potential benefit of lipid-lowering treatment in minor stroke or TIA patients with LDL-C≥2.6 mmol/L.Trial registration number NCT00979589. | Yuesong Pan Runqi Wangqin Hao Li Aoming Jin Jiejie Li Jinxi Lin Xia Meng Ying Xian Daniel T Laskowitz Yongjun Wang | 2022 | Stroke & Vascular Neurology2022，7，4： | 2 |
| 5 | Influence of precursorBi3+/Fe3+ ion concentration on hydrothermal synthesis ofBiFeO3 crystallites显示文摘 | DI L J YANG H XIAN T | 2014 | Ceramics International2014，40，3： | 1 |
| 6 | Resveratrol induces apoptosis of human malignant B cells by activation of caspase-3 and p38 MAP kinase pathways 显示文摘 | Shimizu T Nakazato T Xian M J | 2006 | Biochem Pharmacol2006，71，6： | 1 |
| 7 | Thermal, mechanical, and adhesive properties of HDPE/reactive ethyleneterpotymer blends显示文摘 | Love C T Xian G Karbhari V M | 2007 | J Appl Polym Sci2007，104，： | 1 |
| 8 | Studies on the constituents from the Rhizorm of Alisrm orienatalis显示文摘 | Xian P LI T | 1999 | J of Chinese Sci1999，8，3： | 1 |
| 9 | On further improvement of the variational method in lattice gauge theory显示文摘 | CHEN T L XIAN D C | 1985 | Phys Lett B1985，154，： | 1 |
| 10 | Studies on the constituents from the Rhizoma of Alisma orientalis显示文摘 | Xian P Li T | 1999 | J of Chinese Sci1999，8，3： | 1 |
| 11 | Moisture diffusion and siloxane distributionin integral water repellent concrete 显示文摘 | Wittmann F H Xian Y Z Zhao T J et a/ | 2008 | Restoration of Buildings and Monuments2008，14，1： | 1 |
| 12 | Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling显示文摘 | Ida T Sawa T Ihara H Tsuchiya Y Watanabe Y Kumagai Y Suematsu M Motohashi H Fujii S Matsunaga T Yamamoto M Ono K Devarie O N Xian M Fukuto M F Akaike T | 2014 | Proceedings of the National Academy of Sciences2014，111，21： | 1 |
| 13 | Experience and learning curve of retroperitoneal laparoscopic ureterolithotomy for upper ureteral calculi显示文摘 | Fan T Xian P Yang L | 2009 | J Endourol2009，23，11： | 1 |
| 14 | Global Dynamics of SIS Models with Transport-related 显示文摘 | YASUHIRO T XIAN N JIN G | 2007 | Journal of Mathematical and Applications2007，，4： | 1 |
| 15 | Photocatalytic properties of Bi Fe O3nanoparticles with different sizes显示文摘 | T Xian H Yang J F Dai | 2011 | Mater Lett2011，65，： | 1 |
| 16 | A new method of determining geostresses by the acoustic emission Kaiser effect 显示文摘 | WANG H T XIAN X F YING G Z | 2004 | International Journal of Rock mechanics and Mining Sciences2004，37，： | 1 |
| 17 | Presynaptic defects underlyingimpaired learning and memory function in lipoprotein lipase de-ficient mice显示文摘 | Xian X Liu T Yu J | 2009 | J Neuro Sci2009，29，14： | 1 |
| 18 | Cyclooxygenase-2 mediates the cardio protective effects of the late phase of ischemic preconditioning in conscious rabbits显示文摘 | Ken S Xian L T Yang W | 2000 | Proc Natl Acad Sci2000，97，10： | 1 |
| 19 | Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice 显示文摘 | Xian X Liu T Yu J | 2009 | J Neurosci2009，29，14： | 1 |
| 20 | MR Imaging Features of Primary Mucosal Melanoma of the Eustachian Tube:Report of 2 Cases显示文摘 | Yang B T Wang Z C Xian J F | 2009 | Am J Neuroradiol2009，30，2： | 1 |
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