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| 1 | Collagen scaffolds modified with collagen-binding bFGF promotes the neural regeneration in a rat hemisected spinal cord injury model显示文摘Nerve conduit is one of strategies for spine cord injury(SCI)treatment.Recently,studies showed that biomaterials could guide the neurite growth and promote axon regeneration at the injury site.However,the scaffold by itself was difficult to meet the need of SCI functional recovery.The basic fibroblast growth factor(bFGF)administration significantly promotes functional recovery after organ injuries.Here,using a rat model of T9 hemisected SCI,we aimed at assessing the repair capacity of implantation of collagen scaffold(CS)modified by collagen binding bFGF(CBD-bFGF).The results showed that CS combined with CBD-bFGF treatment improved survival rates after the lateral hemisection SCI.The CS/CBD-bFGF group showed more significant improvements in motor than the simply CS-implanted and untreated control group,when evaluated by the 21-point Basso-Beattie-Bresnahan(BBB)score and footprint analysis.Both hematoxylin and eosin(H&E)and immunohistochemical staining of neurofilament(NF)and glial fibrillary acidic protein(GFAP)demonstrated that fibers were guided to grow through the implants.These findings indicated that administration of CS modified with CBD-bFGF could promote spinal cord regeneration and functional recovery. | SHI Qin GAO Wei HAN XingLong ZHU XueSong SUN Jie XIE Fang HOU XiangLin YANG HuiLin DAI JianWu CHEN Liang | 2014 | Science China(Life Sciences)2014,57,2: | 23 |
| 2 | Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies显示文摘Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood.We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients.After classifying individual cells;we generated a spatial and temporal landscape of glioma that revealed the patterns of invasion between the different sub-regions of gliomas.We also used single-cell inferred copy number variations and pseudotime trajectories to inform on the crucial branches that dominate tumor progression.The dynamic cell components of the multi-region biopsy analysis allowed us to spatially deconvolute with unprecedented accuracy the transcriptomic features of the core and those of the periphery of glioma at single-cell level.Through this rich and geographically detailed dataset,we were also able to characterize and construct the chemokine and chemokine receptor interactions that exist among different tumor and non-tumor cells.This study provides the first spatial-level analysis of the cellular states that characterize human gliomas.It also presents an initial molecular map of the cross-talks between glioma cells and the surrounding microenvironment with single-cell resolution. | Kai Yu Yuqiong Hu Fan Wu Qiufang Guo Zenghui Qian Waner Hu Jing Chen Kuanyu Wang Xiaoying Fan Xinglong Wu John EJ Rasko Xiaolong Fan Antonio lavarone Tao Jiang Fuchou Tang Xiao-Dong Su | 2020 | National Science Review2020,7,8: | 4 |
| 3 | Chokeberry(Aronia melanocarpa)as a new functional food relationship with health:an overview显示文摘As a consumer product,black chokeberry(Aronia melanocarpa)is diffi cult to consume due to its pungent taste.It is mainly used in various food industries to produce a variety of juices,preserves,extracts,fruit teas and nutritional supplements.Traditionally,Potawatomi Native Americans used black chokeberry to treat colds,coughs and fever.It has been found to contain numerous active ingredients.Currently,there are many health and medical products that contain black chokeberry.The purpose of this review is to understand the nutritional benefi ts of black chokeberry and to explore its benefi cial effects on biological systems in vitro,thereby emphasizing its therapeutic prospects. | Yiwen Zhang Yingchun Zhao Xinglong Liu Xueyan Chen Chuanbo Ding Ling Dong Jinping Zhang Shuwen Sun Qiteng Ding Sadia Khatoom Zhiqiang Cheng Wencong Liu Liqian Shen Fengyan Xiao | 2021 | Journal of Future Foods2021,1,2: | 3 |
| 4 | The origins of the broadband photoluminescence from carbon nitrides and applications to white light emitting显示文摘碳氮化物在 700 点由三聚氰胺的热 polycondensation | Zhixing Gan Yun Shan Jiarui Chen Qingfeng Gui Qizhen Zhang Shouping Nie Xinglong Wu | 2016 | Nano Research2016,9,6: | 2 |
| 5 | Development of a mechanical semi-active vibration absorber 显示文摘 | XU Zhenbang GONG Xinglong CHEN Xianmin | 2011 | Advances in Vibration Engineering2011,10,3: | 1 |
| 6 | Directional terahertz holography with thermally active Janus metasurface显示文摘Dynamic manipulation of electromagnetic(EM)waves with multiple degrees of freedom plays an essential role in enhancing information processing.Currently,an enormous challenge is to realize directional terahertz(THz)holography.Recently,it was demonstrated that Janus metasurfaces could produce distinct responses to EM waves from two opposite incident directions,making multiplexed dynamic manipulation of THz waves possible.Herein,we show that thermally activated THz Janus metasurfaces integrating with phase change materials on the meta-atoms can produce asymmetric transmission with the designed phase delays.Such reconfigurable Janus metasurfaces can achieve asymmetric focusing of THz wave and directional THz holography with free-space image projections,and particularly the information can be manipulated via temperature and incident THz wave direction.This work not only offers a common strategy for realizing the reconfigurability of Janus metasurfaces,but also shows possible applications in THz optical information encryption,data storage,and smart windows. | Benwen Chen Shengxin Yang Jian Chen Jingbo Wu Ke Chen Weili Li Yihui Tan Zhaosong Wang Hongsong Qiu Kebin Fan Caihong Zhang Huabing Wang Yijun Feng Yunbin He Biaobing Jin Xinglong Wu Jian Chen Peiheng Wu | 2023 | Light(Science & Applications)2023,12,6: | 1 |
| 7 | Synthesis,charac-terization and application of SnSx(x=1,2) nanoparticles显示文摘 | Gou Xinglong Chen Jun Shen Panwen | 2005 | Mater Chem Phys2005,93,: | 1 |
| 8 | An Artificial Light-Harvesting System with Tunable Fluorescence Color in Aqueous Sodium Dodecyl Sulfonate Micellar Systems for Photochemical Catalysis显示文摘Main observation and conclusion In the present work,an artificial light-harvesting system with fluorescence resonance energy transfer(FRET)is successfully fabricated in aqueous sodium dodecyl sulfonate(SDS)micellar systems.Since the tight and orderly arrangement of dodecyl in the SDS micelles is hydrophobic,tetra-(4-pyridylphenyl)ethylene(4PyTPE)can be easily encapsulated into the hydrophobic layer of SDS micelles through noncovalent interaction,which exhibits aggregation-induced emission(AIE)phenomenon and can be used as energy donor.By using amphoteric sulforhodamine 101(SR101)fluorescent dye attached to the negatively charged surface of SDS micelles through electrostatic interaction as energy acceptor,the light-harvesting FRET process can be efficiently simulated.Through the steady-state emission spectra analysis in the micelle-mediated energy transfer from 4PyTPE to SR101,the fluorescence emission can be tuned and white light emission with CIE coordinates of(0.31,0.29)can be successfully achieved by tuning the donor/acceptor ratio.More importantly,to better mimic natural photosynthesis,the SDS micelles with 4PyTPE and SR101 FRET system showed enhanced catalytic activity in photochemical catalysis for dehalogenation ofα-bromoacetophenone in aqueous solution and the photocatalytic reaction could be extended to gram levels. | Xinglong Li Ying Wang Ao Song Minghui Zhang Mengning Chen Man Jiang Shengsheng Yu Rongzhou Wang Lingbao Xing | 2021 | Chinese Journal of Chemistry2021,39,10: | 1 |
| 9 | Genomic characterisation of a lentogenic Newcastle disease virus strain HX01 isolated from sick pigs in China显示文摘 | Shengli Chen Huafang Hao Xinglong Wang Enqi Du Haijin Liu Tao Yang Yangkun Liu Xiangjing Fu Peng Zhang Zengqi Yang | 2013 | Virus Genes2013,,2: | 1 |
| 10 | Sodium-based dual-ion batteries via coupling high-capacity selenium/graphene anode with high-voltage graphite cathode显示文摘Dual ion batteries(DIBs) exhibit broad application prospects in the field of electrical energy storage(EES)devices with excellent properties,such as high voltage,high energy density,and low cost.In the graphitebased DIBs,high voltage is needed to store enough anions with the formation of anion intercalation compound XCn(X=AlCl4-,PF6-,TFSI-,etc.).Hence,it is difficult for graphite-based DIBs to match proper anodes and electrolytes.Here,an Se/graphene composite is prepared via a convenient method,and assembled into a dual-ion full battery(DIFB) as anode with graphite cathode and 1 mol/L NaPF6 in EC:EMC(1:1,v:v).This DIFB has achieved a high discharge capacity of 75.9 mAh/g and high medium output voltage of 3.5 V at 0.1 A/g.Actually,the suitable anode materials,such as the present Se/graphene composite,are extremely important for the development and application of graphite-based DIBs.This study is enlightening for the design of future low-cost EES devices including graphite-based DIBs. | Xiankun Hou Wenhao Li Yingying Wang Shaofang Li Yunfeng Meng Haiyue Yu Baokuan Chen Xinglong Wu | 2020 | Chinese Chemical Letters2020,31,9: | 1 |
| 11 | Investigation on magnetorheological elastomers based on natural rubber显示文摘 | Chen Lin Gong Xinglong Jiang Wanquan | 2007 | Journal of Materials Science2007,42,14: | 1 |
| 12 | Evaluation of the antioxidant activity of blueberry ethanol extracts under microwave extraction显示文摘Blueberry extract contains diversiform monomers of anthocyanins, whose antioxidant activity determines the functionality of anthocyanidins and the efficacy of extraction technology. The evaluation of the antioxidant activity of anthocyanidins of blueberry ethanol extracts (BEE) was investigated by considering the monomers' identification and thermal degradation in microwave-assisted extraction (MAE). Thirteen monomers of anthocyanins were identified from the extracts of blueberry under MAE, where the highest content was for cyanidin glycosides, and the lowest content was for the malvidin glycosides. The onset temperatures of degradation for anthocyanidins monomers in BEE were 41.07°C-48.50°C, and the glycoside contents of delphinidin, cyanidin, petunidin, peonidin, peonidin, and malvidin, in turn, decreased obviously. The degradation of anthocyanidins with extraction temperature improved, other than weakened, its antioxidant activities in BEE under MAE. The research results may provide valuable guidance for the antioxidant application of extracts from blueberries. | Chenghai Liu Xinglong Zhao Zhen Wang Xianzhe Zheng Liangliang Xue Chai Liu Zhiying Chen Bingfang Zhang | 2022 | International Journal of Agricultural and Biological Engineering2022,15,4: | 1 |
| 13 | Rationalizing the isolation distance needed for field trials involving genetically modified rapeseed (Brassica napus L.) in China显示文摘The isolation distance required for field trials of genetically modified (GM) rapeseed varies widely worldwide, with a 50-400 m distance in most nations contrasting with a minimum 1000-m isolation distance in China. The goal of this study was to evaluate the relevance of current regulations in China regarding the isolation distance needed for GM rapeseed trials. A pollen flow experiment was conducted based on the design of concentric circles, with the GM plants in a 20-m diameter circle at the centre, surrounded by non-GM plants to a distance 60 m from the perimeter of the circle containing GM plants. The rate of pollen flow was the highest at the isolation distance of 0.5 m, where it ranged from 2.3091% to 2.6711%. The general pattern of the pollen flow rate (y) with distance (x) was well described by the equation y = 1.3936x-0.9136 (R 2 = 0.9950). The long-distance pollen flow tested at the isolation distance of 800 m was 0.0018%, which agrees with the theoretical prediction. The results suggested that 300 m, rather than 1000 m, is a reasonable distance to ensure a tolerable threshold of pollen flow (less than 0.01%) under conditions of winter rapeseed production in China. | ZHAO XiangXiang TANG Tang CHEN GuiMin LIU FuXia WANG XingLong BU CuiPing LU ChangMing | 2013 | Chinese Science Bulletin2013,58,13: | 1 |
| 14 | Deciphering the Role of Fluoroethylene Carbonate towards Highly Reversible Sodium Metal Anodes显示文摘Sodium metal anodes(SMAs)sufer from extremely low reversibility(<20%)in carbonate based clectrolytes-this piece of knowledge gained from previous studics has ruled out the application of carbonate solvents for sodium metal batteries.Here,we overturn this conclusion by incorporating fluoroethylene carbonate(FEC)as cosolvent that renders a Na plating/stripping fficiency of>95%with conventional NaPF。salt at a regular concentration(1.0M).The peculiar role of FEC is firstly.unraveled via its involvement into the solvation structure,where a threshold FEC concentration with a coordination number>1.2 is needed in guaranteeing high Na reversibility over the long-term.Specifially,by incorporating an average number of 1.2 FEC molecules into the primary Na*solvation sheath,lowest unoccupied molecular orbital(LUMO)levels of such Nat-FEC solvates undergo further decrease,with spin electrons residing either on the O=C 0(O)moiety of FEC or sharing between Na*and its C=:O bond,which ensures a prior FEC decomposition in passivating the Na surface against other carbonate molecules.Further,by adopting cryogenic tranmission electron microscopy(cryo-TEM),we found that the Na filaments grow into substantially larger diameter from-400nm to>1 pum with addition of FEC upon the threshold value.A.highly crstalline and much thiner(-40 nm)slid-electrolyte interphase(SED)is consequently observed to uniformly wrap the Na surface,in contrast to the severely corroded Na as retrieved from the blank electrolyte.The potence of FEC is further demonstrated in a series of'corrosive solvents'such as ethy!l acetate(EA)。trimethyl phosphate(TMP),and actonitrile(AN)enabling highly reversible SMAs in the otherwise unusable solvent systems. | Xueying Zheng Suting Weng Wei Luo Bo Chen Xiao Zhang Zhenyi Gu Haotian Wang Xiaolu Ye Xuyang Liu Liqiang Huang Xinglong Wu Xuefeng Wang Yunhui Huang | 2022 | Research2022,,2: | 1 |
| 15 | Effect of carbon black on the mechanical performances of magnetorheolog ical elastomers显示文摘 | Chen Lin Gong Xinglong Li Weihua | 2008 | Polymer Testing2008,27,: | 1 |
| 16 | salang wenhua shi qiangzu wenhua de muqin wenhua(Salang Culture is the Mother Culture of the Qiang Culture)显示文摘 | Chen Xinglong | | 0,,04: | 1 |
| 17 | Preparation of water-soluble magnetite nanocrystals through hydrothermal approach显示文摘 | Shouhu Xuan Lingyun Hao Wanquan Jiang Xinglong Gong Yuan Hu Zuyao Chen | 2006 | Journal of Magnetism and Magnetic Materials2006,,2: | 1 |
| 18 | Study of utilizable magnetorheological elastomers 显示文摘 | Gong Xinglong Chen Lin Li Jianfeng | 2007 | International Journal of Modern Physics(B)2007,21,2829: | 1 |
| 19 | Preparation of water-soluble magnetite nanoerystals through hydrothermal approaeh显示文摘 | Shouhu Xuan Lingyun Hao Wanquan Jiang Xinglong Gong Yuan Hu Zuyao Chen | 2007 | Journal of Magnetism and Magnetic Materials2007,308,: | 1 |
| 20 | Samdy of utilizable magnetorheological elastomers显示文摘 | Gong Xinglong Chen Ling | 2007 | International Journal of Modern Phy- sics B2007,21,2829: | 1 |