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| 1 | Reconstruction of 3-D digital cores using a hybrid method显示文摘A 3-D 数字核心描述岩石的毛孔空间微观结构。X 光检查微 CT 扫描是最精确、直接却昂贵的方法获得 3-D 数字核心。在这研究,我们建议联合沉积模拟的一个混合方法并且退火模仿(SA ) 产生 3-D 的方法数字核心基于岩石的 2-D 图象。有沉积模拟的方法开始造 3-D 数字核心,它是为 SA 方法的起始的配置。我们用 SA 方法更新起始的数字核心匹配 2-D 岩石图象的自相关功能并且最后造最后的 3-D 数字核心。与典型 SA 方法相比,混合方法显著地减少了计算时间。本地孔理论被用于份量上比较重建的 3-D 有 X 光检查微 CT 3-D 图象的数字核心。结果显示 3-D 数字核心由混合方法重建了有同质和 X 光检查微 CT 图象的类似于那些的几何连接。形成因素和重建的 3-D 的渗透数字核心用有限元素方法被估计(女性) 并且格子 Boltzmann 方法(LBM ) 分别地。模仿的结果在对试验性的大小的好同意。模拟结果的比较建议数字核心由更多仔细独自比典型 SA 方法反映真运输性质的混合方法重建了。 | Liu Xuefeng Sun Jianmeng Wang Haitao | 2009 | Applied Geophysics2009，6，2： | 28 |
| 2 | PepperHub, an Informatics Hub for the Chili Pepper Research Community显示文摘 | Feng Liu Huiyang Vu Yingtian Deng Jingyuan Zheng Minglei Liu Lijun Ou Bozhi Yang Xiongze Dai Yanqing Ma Shengyu Feng Shuang He Xuefeng Li Zhuqing Zhang Wenchao Chen Shudong Zhou Rong Chen Minmin Liu Sha Yang Ruimin Wei Huadong Li Feng Li Bo Ouyang Xuexiao Zou | 2017 | Molecular Plant2017，10，8： | 13 |
| 3 | Direct low-temperature synthesis of graphene on various glasses by plasma-enhanced chemical vapor deposition for versatile, cost-effective electrodes显示文摘在低温度的各种各样的玻璃底层上的 graphene 的没有催化剂、可伸缩的合成具有到象便宜透明电子学和最先进的显示器那样的众多的应用程序的首要的意义。然而,在这个有希望的研究领域以内的系统的学习远这样仍然保持少见。此处,我们用一个低温度的提高血浆的化学蒸汽免职方法在各种各样的眼镜上报导 graphene 的直接生长。如此的一条灵巧、可伸缩的途径在 400600 的一个生长温度范围在各种各样的玻璃底层上保证一致、没有转移的 graphene | Jingyu Sun Yubin Chen Xin Cai Bangjun Ma Zhaolong Chen Manish Kr. Priydarshi Ke Chen Teng Gao Xiuju Song Qingqing Ji Xuefeng Guo Dechun Zou Yanfeng Zhang Zhongfan Liu | 2015 | Nano Research2015，8，11： | 12 |
| 4 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 5 | 能使体外培养细胞长期存活的技术显示文摘美国科学家的最新研究表明Rho激酶抑制剂(Y-27632)与纤维母细胞饲养细胞合用能够诱导许多组织的正常上皮细胞以及肿瘤上皮细胞在体外无限增值,而不需要转导外源性病毒或细胞基因.例如原始前列腺和乳腺细胞重编程为基底细胞样干细胞样表型并在基底膜中形成有序的前列腺球和乳腺球.相较于筛选稀少的干细胞样细胞,在所述的生长条件下能够在活检组织获取后的5 d~6 d内产生2×106个细胞,能够从冷冻组织少于4个活细胞培养起来.持续的细胞增殖依赖于纤维母细胞饲养细胞和Y-27632两者,进行有条件重组的细胞(CRCs)保持了正常的核型和非致瘤性.该技术也能够有效建立人和啮齿类动物肿瘤细胞的培养系.例如,从人前列腺癌建立的CRCs表现出第13号染色体的不稳定性,在基底膜中的异常增殖以及在有严重合并免疫缺陷的老鼠中形成肿瘤.这种从少量活检样本和冷冻组织迅速产生许多肿瘤细胞的能力为基于细胞的诊断和治疗(包括测试化学敏感性)提供了很大机会并大大提高了生物银行的价值.另外,CRC方法能够对取自体内的上皮细胞进行遗传操作以及随后的自体体内评估. | Xuefeng Liu Virginie Ory Sandra Chapman | 2012 | 中国烧伤创疡杂志2012，24，3： | 11 |
| 6 | Potential association of hyperhomocysteinemia with the progression of IgA nephropathy: a retrospective study显示文摘 | Duan Shuwei Liu Shuwen Sun Xuefeng Zheng Ying Liu Linchang Yao Feixiang Wu Jie | 2014 | Chinese Medical Journal2014，，10： | 11 |
| 7 | Total mesopancreas excision for pancreatic head cancer: analysis of 120 cases显示文摘Objective: To evaluate the feasibility and safety of total mesopancreas excision(TMpE) in the treatment of pancreatic head cancer. Methods: The clinical and pathological data of 120 patients with pancreatic head cancer who had undergone TMpE in our center from May 2010 to January 2014 were retrospectively analyzed. Results: The mean operative time was(275.0±50.2) min and the average intra-operative blood loss was(390.0±160.5) mL. Post-operative complications were reported in 45 patients, while no peri-operative death was noted. The specimen margins were measured in three dimensions, and 86 patients(71.6%) achieved R0 resection. Conclusions: TMpE is safe and feasible for pancreatic head cancer and is particularly helpful to increase the R0 resection rate. | Wenguang Wu Xu'an Wang Xiangsong Wu Maolan Li Hao Weng Yang Cao Ruifa Bao Sijun Su Jianhua Lu Wei Gong Weibin Shi Jun Gu Xuefeng Wang Yingbin Liu Zhiwei Quan Shuyou Peng | 2016 | Chinese Journal of Cancer Research2016，28，4： | 10 |
| 8 | Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus显示文摘Increasing the self-resistance levels of Streptomyces is an effective strategy to improve the production of antibiotics.To increase the oxytetracycline(OTC) production in Streptomyces rimosus,we investigated the cooperative effect of three co-overexpressing OTC resistance genes:one gene encodes a ribosomal protection protein(otrA) and the other two express efflux proteins(otrB and otrC).Results indicated that combinational overexpression of otrA,otrB,and otrC(MKABC) exerted a synergetic effect.OTC production increased by 179%in the recombinant strain compared with that of the wild-type strain M4018.The resistance level to OTC was increased by approximately two-fold relative to the parental strain,thereby indicating that applying the cooperative effect of self-resistance genes is useful to improve OTC production.Furthermore,the previously identified cluster-situated activator OtcR was overexpressed in MKABC in constructing the recombinant strain MKRABC;such strain can produce OTC of approximately7.49 g L^((-1)),which represents an increase of 19%in comparison with that of the OtcR-overexpressing strain alone.Our work showed that the cooperative overexpression of self-resistance genes is a promising strategy to enhance the antibiotics production in Streptomyces. | Shouliang Yin Xuefeng Wang Mingxin Shi Fang Yuan Huizhuan Wang Xiaole Jia Fang Yuan Jinliang Sun Tiejun Liu Keqian Yang Yuxiu Zhang Keqiang Fan Zilong Li | 2017 | Science China(Life Sciences)2017，60，9： | 10 |
| 9 | A Discussion on the Origin of Shale Reservoir Inter-Laminar Fractures in the Shahejie Formation of Paleogene, Dongying Depression显示文摘This paper was conducted on the shale reservoir in the Dongying depression in the Shahejie Formation of Paleogene. Based on detailed core description, rock thin sections, argon ion polishing, scanning electron microscopy(SEM) analysis, CT scanning and carbon-oxygen isotopic test, the formation mechanism of the inter-laminar fractures(or seams) and their development conditions were discussed by comprehensive analysis of the diagenetic evolution features and the reservoir space evolution characteristics. The results show that the laminated composite pattern in Dongying depression was dominated by vertical distribution of laminated calcite and clay minerals. Contrasted to the traditional understanding, development degree of inter-laminar fractures was much lower. Pure fluid between layers cannot exist without framework minerals, and the pre-existing well connected pore or horizontal overpressure micro seam was favorable paths of fluid migration. From the points of inter-laminar fractures origin mechanism and its evolution, the so called seams, were much more complex than traditional understanding that hydrocarbon generation raised the pore pressure and led to the parallel microfractures. But the inter-laminar fractures had little relationship with that whether the lamination was developed or bedding boundary was clear or not. In fact, the shale reservoir inter-laminar fractures were not rigorous fracture. They were controlled by pre-existing inter-granular pore(or seam) or dissolved pore, which distributed along carbonate laminae boundary and were connected by later super pressure, dissolution and the seepage force. And the development conditions were burial depth(bigger than 3 000 m) and the Ro value(>0.6%). Discussion on its origin and evolution has important petroleum geological significance on optimizing reservoir segment and favorable target areas selection. | Huimin Liu Shun Zhang Guoqi Song Shoupeng Zhang Xuefeng Hao Zhonghuai Xie Ningning Xu Peng Liu | 2017 | Journal of Earth Science2017，28，6： | 10 |
| 10 | The High Energy X-ray telescope (HE) onboard the Insight-HXMT astronomy satellite显示文摘The Insight-Hard X-ray Modulation Telescope(Insight-HXMT) is a broadband X-ray and γ-ray(1-3000 ke V) astronomy satellite. One of its three main telescopes is the High Energy X-ray telescope(HE). The main detector plane of HE comprises 18 Na I(Tl)/Cs I(Na) phoswich detectors, where Na I(Tl) is used as the primary detector to measure ~ 20-250 ke V photons incident from the field of view(FOV) defined by collimators, and Cs I(Na) is used as the active shielding detector to Na I(Tl) by pulse shape discrimination. Additionally, Cs I(Na) is used as an omnidirectional γ-ray monitor. The HE collimators have a diverse FOV,i.e. 1.1°×5.7°(15 units), 5.7°×5.7°(2 units), and blocked(1 unit). Therefore, the combined FOV of HE is approximately5.7°×5.7°. Each HE detector has a diameter of 190 mm resulting in a total geometrical area of approximately 5100 cm2, and the energy resolution is ~15% at 60 ke V. For each recorded X-ray event by HE, the timing accuracy is less than 10 μs and the deadtime is less than 10 μs. HE is used for observing spectra and temporal variability of X-ray sources in the 20-250 ke V band either by pointing observations for known sources or scanning observations to unveil new sources. Additionally, HE is used for monitoring the γ-ray burst in 0.2-3 Me V band. This paper not only presents the design and performance of HE instruments but also reports results of the on-ground calibration experiments. | CongZhan Liu YiFei Zhang XuFang Li XueFeng Lu Zhi Chang ZhengWei Li AiMei Zhang YongJie Jin HuiMing Yu Zhao Zhang MinXue Fu YiBao Chen JianFeng Ji YuPeng Xu JingKang Deng RenCheng Shang GuoQing Liu FangJun Lu ShuangNan Zhang YongWei Dong TiPei Li Mei Wu YanGuo Li HuanYu Wang BoBing Wu YongJie Zhang Zhi Zhang ShaoLin Xiong Yuan Liu Shu Zhang HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 9 |
| 11 | Preliminary assessing no-surgical treatment response in bronchogenic carcinoma with double-phase contrast material-enhanced computed tomography显示文摘评估双阶段的功效的目的在 preliminarily 在 bronchogenic 癌估计没有外科的治疗反应对比提高材料的计算断层摄影术(CT ) 。有在没有外科的治疗以后的 bronchogenic 癌的 52 个病人经历了双阶段的方法对比提高材料的计算断层摄影术。在非离子的对比材料经由赌注被管理以后,二螺线 CT 扫描分别地在 25 和 90 秒点被获得以由使用一个汽车注射者的 4 mL/s 的率的肘的静脉。每扫描上的 Precontrast 和柱子对比变细被记录,山峰高度是计算的。改进模式在在对比媒介的注射以后在 25 和 90 秒点获得的图象上被评估。结果 Precontrast 变细,在 25 和 90 秒点的柱子对比变细是 42.20 ± 7.43 胡, 57.35 ± 10.09 胡和 71.85 ± 12.45 胡分别地。在 precontrast 变细的统计上重要的差别都没在我们在治疗前在情况中被获得的旧学习(吝啬的 precontrast 变细 40.70 胡) 在学习和结果在我们的结果之间被发现(t = 1.455, P = 0.152 >
0.05 ) 。在没有外科的治疗以后的 bronchogenic 癌的山峰高度(29.46 ± 10.85 胡) 是比在在我们的旧学习获得的治疗前的 bronchogenic 癌的显著地低的(吝啬的山峰高度 35.79 胡;t = 4.206, P = 0.001 <
0.05 ) 。52 个盒子中的 32 个在 90 秒点显示出同类的改进。32 个盒子,与不同类的改进有 21, 7 与不同类的改进, 2 与中央改进并且 2 与在 25 秒点的外部改进。在没有外科的处理以后的结论 Bronchogenic 癌在对比材料的管理以后显示出渐渐的增加到山峰高度。山峰高度能反映 bronchogenic 癌的血供应并且可能是为在 bronchogenic 癌的没有外科的治疗反应的评估的索引。 | Shenjiang Li Yong Zhao Yan Zhu Feng Zhu Debin Liu Wenjie Liang Xuefeng Cui Wenjie Bi | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，3： | 9 |
| 12 | Characteristics of internal-wave and internal-tide deposits and their hydrocarbon potential显示文摘内部波浪、内部潮的存款的学习在最后十年期间是 sedimentology 上的一个新研究领域。内部波浪和内部潮导致的深海的拖拉水流在现代的海地板上被开发,它能形成不仅各种小规模和疏开深海的拖拉水流存款,而且在 km 尺寸的大规模沉积波浪可伸缩。在这篇论文,在海洋学的内部波浪和内部潮的概念和特征被介绍,并且特征,沉积序列,沉积 microfacies 和沉积在深海底部发现的内部波浪、内部潮的存款和大规模沉积波浪的起源当模特儿被总结。在内部波浪、内部潮的存款和石油之间的关系被讨论,并且最后内部波浪、内部潮的存款被显示是为石油探索的一个新潜在的领域。 | He Youbin Gao Zhenzhong Luo Jinxiong Luo Shunshe Liu Xuefeng | 2008 | Petroleum Science2008，5，1： | 9 |
| 13 | OsCIPK7 point-mutation leads to conformation and kinase-activity change for sensing cold response显示文摘Calcineurin B-like interacting protein kinases(CIPKs) play important roles via environmental stress.However, less is known how to sense the stress in molecular structure conformation level. Here, an Os CIPK7 mutant via TILLING procedure with a point mutation in the kinase domain showed increased chilling tolerance, which could be potentially used in the molecular breeding. We found that this point mutation of Os CIPK7 led to a conformationalchange in the activation loop of the kinase domain,subsequently with an increase of protein kinase activity,thus conferred an increased tolerance to chilling stress. | Dajian Zhang Xiaoyu Guo Yunyuan Xu Hao Li Liang Ma Xuefeng Yao Yuxiang Weng Yan Guo Chun-Ming Liu Kang Chong | 2019 | Journal of Integrative Plant Biology2019，61，12： | 8 |
| 14 | Cryogenic minimum quantity lubrication machining: from mechanism to application显示文摘Cutting fluid plays a cooling-lubrication role in the cutting of metal materials.However,the substantial usage of cutting fluid in traditional flood machining seriously pollutes the environment and threatens the health of workers.Environmental machining technologies,such as dry cutting,minimum quantity lubrication(MQL),and cryogenic cooling technology,have been used as substitute for flood machining.However,the insufficient cooling capacity of MQL with normal-temperature compressed gas and the lack of lubricating performance of cryogenic cooling technology limit their industrial application.The technical bottleneck of mechanical-thermal damage of difficult-to-cut materials in aerospace and other fields can be solved by combining cryogenic medium and MQL.The latest progress of cryogenic minimum quantity lubrication(CMQL)technology is reviewed in this paper,and the key scientific issues in the research achievements of CMQL are clarified.First,the application forms and process characteristics of CMQL devices in turning,milling,and grinding are systematically summarized from traditional settings to innovative design.Second,the cooling-lubrication mechanism of CMQL and its influence mechanism on material hardness,cutting force,tool wear,and workpiece surface quality in cutting are extensively revealed.The effects of CMQL are systematically analyzed based on its mechanism and application form.Results show that the application effect of CMQL is better than that of cryogenic technology or MQL alone.Finally,the prospect,which provides basis and support for engineering application and development of CMQL technology,is introduced considering the limitations of CMQL. | Mingzheng LIU Changhe LI Yanbin ZHANG Qinglong AN Min YANG Teng GAO Cong MAO Bo LIU Huajun CAO Xuefeng XU Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafz Muhammad ALI Shubham SHARMA | 2021 | Frontiers of Mechanical Engineering2021，16，4： | 8 |
| 15 | Assessing the impacts of human activities and climate variations on grassland productivity by partial least squares structural equation modeling(PLS-SEM)显示文摘The cause-effect associations between geographical phenomena are an important focus in ecological research. Recent studies in structural equation modeling(SEM) demonstrated the potential for analyzing such associations. We applied the variance-based partial least squares SEM(PLS-SEM) and geographically-weighted regression(GWR) modeling to assess the human-climate impact on grassland productivity represented by above-ground biomass(AGB). The human and climate factors and their interaction were taken to explain the AGB variance by a PLS-SEM developed for the grassland ecosystem in Inner Mongolia, China. Results indicated that 65.5% of the AGB variance could be explained by the human and climate factors and their interaction. The case study showed that the human and climate factors imposed a significant and negative impact on the AGB and that their interaction alleviated to some extent the threat from the intensified human-climate pressure. The alleviation may be attributable to vegetation adaptation to high human-climate stresses, to human adaptation to climate conditions or/and to recent vegetation restoration programs in the highly degraded areas. Furthermore, the AGB response to the human and climate factors modeled by GWR exhibited significant spatial variations. This study demonstrated that the combination of PLS-SEM and GWR model is feasible to investigate the cause-effect relation in socio-ecological systems. | SHA Zongyao XIE Yichun TAN Xicheng BAI Yongfei LI Jonathan LIU Xuefeng | 2017 | Journal of Arid Land2017，9，4： | 8 |
| 16 | MOF-Derived Ni1-xCox@Carbon with Tunable Nano-Microstructure as Lightweight and Highly Efficient Electromagnetic Wave Absorber显示文摘Intrinsic electric-magnetic property and special nano-micro architecture of functional materials have a significant effect on its electromagnetic wave energy conversion,especially in the microwave absorption(MA) field.Herein,porous Ni1-xCox@Carbon composites derived from metal-organic framework(MOF)were successfully synthesized via solvothermal reaction and subsequent annealing treatments.Benefiting from the coordination,carbonized bimetallic Ni-Co-MOF maintained its initial skeleton and transformed into magnetic-carbon composites with tunable nano-micro structure.During the thermal decomposition,generated magnetic particles/clusters acted as a catalyst to promote the carbon sp^2 arrangement,forming special core-shell architecture.Therefore,pure Ni@C microspheres displayed strong MA behaviors than other Ni1-xCox@Carbon composites.Surprisingly,magnetic-dielectric Ni@C composites possessed the strongest reflection loss value-59.5 dB and the effective absorption frequency covered as wide as 4.7 GHz.Meanwhile,the MA capacity also can be boosted by adjusting the absorber content from 25% to 40%.Magnetic-dielectric synergy effect of MOF-derived Ni1-xCox@Carbon microspheres was confirmed by the off-axis electron holography technology making a thorough inquiry in the MA mechanism. | Lei Wang Mengqiu Huang Xuefeng Yu Wenbin You Jie Zhang Xianhu Liu Min Wang Renchao Che | 2020 | Nano-Micro Letters2020，12，11： | 7 |
| 17 | Surface-enhanced Raman scattering on dielectric microspheres with whispering gallery mode resonance显示文摘Conventionally, metallic nanostructures are used for surface-enhanced Raman spectroscopy(SERS), but recently there has been increasing interest in the enhancement of Raman scattering from dielectric substrates due to their improved stability and biocompatibility compared with metallic substrates. Here, we report the observation of enhanced Raman scattering from rhodamine 6 G molecules coated on silica microspheres. We excite the whispering gallery modes(WGMs) supported in the microspheres with a tapered fiber coupler for efficient WGM excitation, and the Raman enhancement can be attributed to the WGM mechanism. Strong resonance enhancement in pump laser intensity and modified Raman emission from the Purcell effect in the microsphere resonator are observed from the experiment and compared with theoretical results. A total Raman enhancement factor of 1.4 × 10~4 is observed, with contribution mostly from the enhancement in pump laser intensity. Our results show that, with an efficient pumping scheme, dielectric microspheres are a viable alternative to metallic SERS substrates. | STEVEN H.HUANG XUEFENG JIANG Bo PENG COREY JANISCH ALEXANDER COCKING SAHIN KAYA OZDEMIR ZHIWEN LIU LAN YANG | 2018 | Photonics Research2018，6，5： | 7 |
| 18 | Towards single-molecule optoelectronic devices显示文摘Benefiting from the development of molecular electronics and molecular plasmonics, the interplay of light and electronic transport in molecular junctions has attracted growing interest among researchers in both fields, leading to a new research direction of 'single-molecule optoelectronics'. Here, we review the latest developments of photo-modulated charge transport,electroluminescence and Raman spectroscopy from single-molecule junctions, and suggest future directions for single-molecule optoelectronics. | Lijue Chen Anni Feng Maoning Wang Junyang Liu Wenjing Hong Xuefeng Guo Dong Xiang | 2018 | Science China Chemistry2018，61，11： | 7 |
| 19 | Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings:A positive feedback loop regulation显示文摘Glioma is the most common type of primary brain tumors in the central nervous system(CNS). Migfilin occurs in human glioma and enhances cellular motility via the epidermal growth factor receptor(EGFR)pathway. However, the underlying molecular mechanism is not fully understood. In this study, we found that Migfilin promoted matrix metalloproteinase-2(MMP-2) activity, and restrained the expression of tissue inhibitor of metalloproteinase 2(TIMP2), which is an MMP-2 inhibitor. Functional and structural studies showed that the LIM1 domain of Migfilin was required for Migfilin-mediated TIMP2 expression inhibition and MMP-2 activity, and was also necessary in promoting cell motility. Furthermore, Migfilininduced EGFR phosphorylation was greatly reduced by MMP-2 inhibitor(GM6001) or si RNA, while Migfilin-induced MMP-2 activation was also blocked by the EGFR inhibitor(AG1478) or si RNA. MMP-2 and EGFR inhibitors and their si RNAs can block Migfilin-induced migration and invasion, respectively.These results demonstrated that EGFR and MMP-2 signalings may form a positive feedback loop to enhance Migfilin-induced migration and invasion. Finally, we detected that the expression of Migfilin,EGFR phosphorylation(Tyr1173) and MMP-2 activity had a positive correlation in the clinical glioma sample. Taken together, these results suggest that Migfilin is a critical regulator in cellular motility by driving the EGFR-MMP-2 feedback loop, and may be considered as a potential therapeutic target in glioma. | Yunwei Ou Qingnan Wu Chuanyue Wu Xuefeng Liu Yongmei Song Qimin Zhan | 2017 | Journal of Genetics and Genomics2017，44，12： | 7 |
| 20 | Optical observations of LIGO source GW 170817 by the Antarctic Survey Telescopes at Dome A,Antarctica显示文摘The LIGO detection of gravitational waves(GW) from merging black holes in 2015 marked the beginning of a new era in observational astronomy. The detection of an electromagnetic signal from a GW source is the critical next step to explore in detail the physics involved. The Antarctic Survey Telescopes(AST3),located at Dome A, Antarctica, is uniquely situated for rapid response time-domain astronomy with its continuous night-time coverage during the austral winter. We report optical observations of the GW source(GW 170817) in the nearby galaxy NGC 4993 using AST3. The data show a rapidly fading transient at around 1 day after the GW trigger, with the i-band magnitude declining from 17:23 ± 0:13 magnitude to 17:72 ± 0:09 magnitude in ~1:8 h. The brightness and time evolution of the optical transient associated with GW 170817 are broadly consistent with the predictions of models involving merging binary neutron stars. We infer from our data that the merging process ejected about ~10^(-2) solar mass of radioactive material at a speed of up to 30% the speed of light. | lei hu xuefeng wu igor andreoni michael c.b.ashley jeff cooke xiangqun cui fujia du zigao dai bozhong gu yi hu haiping lu xiaoyan li zhengyang li ensi liang liangduan liu bin ma zhaohui shang tianrui sun n.b.suntzeff charling tao syed a.uddin lifan wang xiaofeng wang haikun wen di xiao jin xu ji yang shihai yang xiangyan yuan hongyan zhou hui zhang jilin zhou zonghong zhu | 2017 | Science Bulletin2017，62，21： | 6 |
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