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| 1 | A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30显示文摘Mitochondrial 熔化是为正常 mitochondrial 功能和 mitochondrial DNA 继承混合并且统一 mitochondrial 分隔空间的一个高度协调的过程。Dysregulated mitochondrial 熔化原因 mitochondrial 破碎,反常 mitochondrial 生理学和继承,并且有原因地与很多 neuronal 疾病被连接了。这里,我们识别了 potently 导致了 mitochondrial 熔化在在 Mfn1 或 Mfn2 是缺乏的房间恢复 mitochondrial 网络和氧化呼吸的 diterpenoid 衍生物 15-oxospiramilactone (S3 ) 。线粒体局部性的 deubiquitinase USP30 是 S3 的一个目标。由 S3 的 USP30 的抑制导致 Mfn1/2 的 non-degradative ubiquitination 的增加,它提高 Mfn1 和 Mfn2 活动并且支持 mitochondrial 熔化。通过 USP30 的一个禁止者的使用,因此,我们的学习揭开在支持 mitochondrial 的 Mfns 的 non-degradative ubiquitination 的异乎寻常的功能熔化。 | Wen Yue Ziheng Chen HaiYang Li Chen Yan Ming Chen Du Feng Chaojun Yan Hao Wu Lei Du Yueying Wang Jinhua Liu Xiaohu Huang Laixin Xia Lei Liu Xiaohui Wang Haijing Jin Jun Wang Zhiyin Song Xiaojiang Hao Quan Chen | 2014 | Cell Research2014，24，4： | 18 |
| 2 | Diffusion bonding of AlCoCrFeNi2.1 eutectic high entropy alloy to TiAl alloy显示文摘High entropy alloys have special microstructure and remarkable properties.To explore their potential engineering application in high temperature structures,the microstructure evolution of bonding interface,the elemental diffusion behavior and mechanical property of the diffusion bonded joint between AlCoCrFeNi2.1eutectic high entropy alloy(EHEA)and TiAl alloy were investigated.Four reaction layers(rodlike B2 phase,Al(Co,Ni)2Ti,τ3-Al3NiTi2+TiAl,τ3-Al3NiTi2+TiAl+Ti3Al)formed in the diffusion zone near FCC phase of EHEA,but three layers(Al(Co,Ni)2Ti,τ3-Al3Ni Ti2+Ti Al,τ3-Al3Ni Ti2+Ti Al+Ti3Al)formed near B2 phase.Al and Ni controlled the reaction diffusion of EHEA and TiAl alloy,coarsened the acicular precipitated B2 phase and turned Ti Al phase into Al(Co,Ni)2Ti andτ3-Al3NiTi2 phases.All these reaction layers grew in a parabolic manner as a function of bonding temperature.Rodlike B2 phase has the lowest growth activation energy of 125.2 kJ/mol,and the growth activation energy ofτ3-Al3Ni Ti2+TiAl layer near B2 phase is much lower than that near FCC phase.The penetration phenomenon and convex structure formed in the diffusion zone,which resulted in interlocking effect and enhanced the strength of resultant joints.The highest shear strength of 449 MPa was achieved at 950℃.And the brittle fracture generally initiated at the interface between Al(Co,Ni)2Ti andτ3-Al3NiTi2+TiAl layers. | Peng Li Shuai Wang Yueqing Xia Xiaohu Hao Honggang Dong | 2020 | Journal of Materials Science & Technology2020，42，10： | 8 |
| 3 | Gold nanocages as multifunctional materials for nanomedicine显示文摘在在红外线附近的区域和空内部由悦耳的局部性的表面电浆子回声山峰展示了, Au nanocages 代表在最近的年里获得了可观的注意的多功能的 nanomaterials 的一个新奇的班。这短评论在 nanomedicine 在 Au nanocages 的能力上总结我们的最近的工作。我们以对 Au nanocages 的合成的简短描述开始并且为 Au nanocages 的可伸缩起来的生产加亮我们的最近的协议。我们然后使用很多个例子说明 Au nanocages 怎么能关于诊断和治疗贡献 nanomedicine。 | Xiaohu Xia | 2014 | Frontiers of physics2014，9，3： | 6 |
| 4 | Full-parameter vision navigation based on scene matching for aircrafts显示文摘Vision navigation based on scene matching between real-time images and a reference image has many advantages over the commonly used inertial navigation system(INS),such as no cumulative measurement errors for long-endurance flight.Recent developments in vision navigation are mainly used for partial navigation parameters measurements,such as the position and the relative velocity,which cannot meet the requirements of completely autonomous navigation.We present the concept,principle and method of full-parameter vision navigation(FPVN)based on scene matching.The proposed method can obtain the three-dimensional(3D)position and attitude angles of an aircraft by the scene matching for multiple feature points instead of a single point in existing vision navigations.Thus,FPVN can achieve the geodetic position coordinates and attitude angles of the aircraft and then the velocity vector,attitude angular velocity and acceleration can be derived by the time differentials,which provide a full set of navigation parameters for aircrafts and unmanned aerial vehicles(UAVs).The method can be combined with the INS and the cumulative errors of the INS can be corrected using the measurements of FPVN rather than satellite navigation systems.The approach provides a completely autonomous and accurate navigation method for long-endurance flight without the help of satellites. | YU QiFeng SHANG Yang LIU XiaoChun LEI ZhiHui LI Xiang ZHU XianWei LIU XiaoLin YANG Xia SU Ang ZHANG XiaoHu ZHANG HongLiang | 2014 | Science China(Information Sciences)2014，57，5： | 3 |
| 5 | Full-spectrum cell-free RAN for 6G systems:system design and experimental results显示文摘With distributed transceivers and scalable cooperative transmission,cell-free massive multipleinput multiple-output(CF-mMIMO)technology eliminates the“cells”of traditional mobile communications,thereby significantly improving the performance of wireless networks.CF-mMIMO is considered as a major technical tool for achieving the key performance indicators of sixth generation(6G)mobile communication systems.In this paper,a scalable implementation architecture for CF-mMIMO is proposed,based on which potential key technologies such as channel information acquisition,transceiver design,dynamic user and access point association,and novel duplexing are introduced.Finally,based on low-cost commercial access points,a CF-mMIMO testbed with 64 transmit and receive antennas is developed,and the performance of the distributed receiver design is evaluated. | Dongming WANG Xiaohu YOU Yongming HUANG Wei XU Jiamin LI Pengcheng ZHU Yanxiang JIANG Yang CAO Xinjiang XIA Ziyang ZHANG Qingji JIANG Pan WANG Dongjie LIU Kang ZHENG Mengting LOU Jing JIN Qixing WANG Jiangzhou WANG | 2023 | Science China(Information Sciences)2023，66，3： | 3 |
| 6 | Peroxidase-like properties of Ruthenium nanoframes显示文摘This work reports the inherent peroxidase-like properties of Ruthenium(Ru) nanoframes. After templating with Palladium(Pd) seeds, Ru nanoframes with an octahedral shape, average edge length of 6.2 nm, and thickness of 1.8 nm were synthesized in high purity([95 %) and good uniformity. Using the oxidation of 3,30,5,50-tetramethylbenzidine(TMB) by H2O2 as a model catalytic reaction, the Ru frames were demonstrated to be approximately three times more active than natural peroxidases in catalyzing the formation of colored products. As compared to their natural counterparts, Ru frames have a stronger binding affinity to TMB as well as a weaker binding affinity to hydrogen peroxide during the catalysis. The Ru frames as peroxidase mimics proved to be chemically and thermally stable. This work represents the first demonstration of Ru nanostructure-based peroxidase mimics and is therefore expected to inspire future research on bio-applications of Ru nanomaterials. | Haihang Ye Jacob Mohar Qingxiao Wang Massimo Catalano Moon J.Kim Xiaohu Xia | 2016 | Science Bulletin2016，61，22： | 3 |
| 7 | Discovery and significance of buried paleoearthquake of the early Shang Dynasty (1260-1520 BC) in Xuecun,Xingyang,Henan Province,China显示文摘Due to the South-to-North Water Diversion Project,the salvage archaeological excavations were conducted in Xuecun,Xingyang city,Henan Province,China,by the Institute of Cultural Relics and Archaeology of Henan Province in 2005 and 2006.Ample evidence for a paleoearthquake was found during the excavation in the Xuecun archaeological site.The evidence includes faults,two small grabens and a series of ground fissures.These geological structures are considered to be generated by the earthquake.Based on the relationship between the paleoseismic relics and the cultural layers excavated in the site,we inferred that the earthquake took place in the early Shang Dynasty (the Erligang period).The AMS 14C dates of charcoal from ash pits in the site indicate that the earthquake occurred between 1260 BC and 1520 BC.The paleoearthquake during this period was first discovered in the Central Plain of China.This discovery not only extents the scope of paleoseismic investigation,but also provides valuable information for safety evaluation of the South-to-North Water Diversion Project. | XIA ZhengKai ZHANG XiaoHu CHU XiaoLong ZHANG JunNa | 2010 | Chinese Science Bulletin2010，55，12： | 1 |
| 8 | Synthesis and Light Scattering Study of Mierogels With Interpenetrating Polymer Networks 显示文摘 | XIA Xiaohu HU Zhibing | 2004 | Langmuir2004，20，6： | 1 |
| 9 | Simulating land use dy- namics under planning policies by integrating artificial immune systems with cellular automata显示文摘 | Liu Xiaoping Li Xia Shi Xiaohu | 2010 | Intemational Journal of Geo- graphical Information Science2010，24，5： | 1 |
| 10 | The path to 5G:mmWave aspects显示文摘The wide spectrum and propagation characteristics over the air give mmWave communication unique advantages as well as design challenges for 5G applications.To increase the system speed,capacity,and coverage,there is a need for innovation in the RF system architecture,circuit,antenna,and package in terms of implementation opportunities and constraints.The discuss mmWave spectrum characteristics,circuits,RF system architecture,and their implementation issues are discussed.Moreover,the transmitter key components,i.e.,the receiver,antenna,and packaging are reviewed. | LI Lianming NIU Xiaokang CHAI Yuan CHEN Linhui ZHANG Tao CHENG Depeng XIA Haiyang WANG Jiangzhou CUI Tiejun YOU Xiaohu | 2016 | Journal of Communications and Information Networks2016，1，2： | 1 |
| 11 | Carbide precipitates and mechanical properties of medium Mn steel joint with metal inert gas welding显示文摘Medium Mn steel was metal inert gas(MIG)welded with NiCrMo-3 and 307 Si filler wires.The effect of filler wires on the microstructure and mechanical properties of joint was investigated,and the carbide precipitates were contrastively discussed.The results revealed that the microstructure of weld metal,heat-affected zone and base metal are austenite.Obvious grain coarsening occurred in the heat-affected zone(HAZ),and the maximum grain size grew up to 160μm.In HAZ,C and Cr segregated at grain boundaries,the carbides was identified as Cr7 C3.The dispersive(Nb,Mo)C phase was also found in weld metal with NiCrMo-3 filler wire.All the welded joints failed in HAZ during tensile tests.The tensile strength of welded joint with NiCrMo-3 filler wire was 675 MPa,which is much higher than that with307 Si filler wire.In comparison to base metal,higher microhardness and lower impact toughness were obtained in HAZ for these two welded joints,which was attributed to the precipitation of Cr7 C3 phase and grain coarsening.The impact toughness around the fusion line is the worst for these two welded joints. | Jiang Yang Honggang Dong Yueqing Xia Peng Li Xiaohu Hao Yaqiang Wang Wei Wu Baosen Wang | 2021 | Journal of Materials Science & Technology2021，，16： | 1 |
| 12 | Formation and volume phase transition of hydroxypropyl cellulose micro- gels in salt solution 显示文摘 | Xia Xiaohu Tang Shijun Lu Xihua | 2003 | Macromolecules2003，36，10： | 1 |
| 13 | 4-1 Dielectronic Recombination of 36Ar15+ and 112Sn34+ at the CSRm显示文摘The total recombination rate coefficients of lithium-like 36Ar15+ ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP[1]. Fig. 1 (a) shows the DR spectrum for electron energy from 0 to 35 eV in the center-of-mass (c.m.) frame involving all the DR resonances associated with 2s1=2!2p1=2 and 2s1=2!2p3=2 excitations. | Huang Zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Xu Xin Zhu Linfan Xu Weiqing Mao Lijun Li Jie Zhang Xiaohu Ma Xiaoming Yan Tailai Yang Jiancheng Yuan Youjin Xiao Guoqing Xia Jiawen Xie Luyou Dong Chenzhong DR collaboration | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 14 | Special focus on distributed storage coding显示文摘Due to their low cost and feasibility, distributed storage systems (DSSs) have been widely applied in large data centers, peer-to-peer storage systems such as Ocean Store, Total Recall, and DHash++, and for storage in wireless networks. However, as the storage scale dramatically increases, reliability becomes a critical issue in applications involving the DSSs. The most efficient way to guarantee reliability is to employ erasure coding. However, it brings many new challenges that need to be addressed in terms of scalable deployment, security, efficiency, new devices, and so on. | Xiaohu TANG Shu-Tao XIA Chao TIAN Qin HUANG Xiang-Gen XIA | 2018 | Science China(Information Sciences)2018，61，10： | 0 |
| 15 | Novel perspective for urban water resource management: 5R generation显示文摘Demand for water is expanding with increases in population,particularly in urban areas in developing countries.Additionally,urban water system needs a novel perspective for upgradation with urbanization.This perspective presents a novel 5R approach for managing urban water resources:Recover(storm water),Reduce(toilet flushing water),Recycle(gray water),Resource(black water),and Reuse(advanced-treated wastewater).The 5R generation incorporates the latest ideas for harvesting storm water,gray water,and black water in its several forms.This paper has briefly demonstrated each R of 5R generation for water treatment and reuse.China has the chance to upgrade its urban water systems according to 5R principles.Already,a demonstration project of 5R generation has been installed in Qingdao International Horticultural Exposition,and Dalian International Convention Center(China)has applied 5R,achieving over 70%water saving.The 5R offers promise for moving solutions for urban water scarcity from“hoped for in the future”to“realistic today”. | Lijie Zhou Hongwu Wang Zhiqiang Zhang Jian Zhang Hongbin Chen Xuejun Bi Xiaohu Dai Siqing Xia Lisa Alvarez-Cohen Bruce ERittmann | 2021 | Frontiers of Environmental Science & Engineering2021，15，1： | 0 |
| 16 | 6-2 Progress of the IH-DTL Accelerator for HIRFL Injector显示文摘As a powerful heavy ion injector for HIRFL, the SSC-Linac is under constructing at IMP. In 2015, the manu-facture of the rst IH-DTL cavity has been nished. Low power measurement and high power conditioning were performed in sequencely. The recent R&D progress of the SSC-Linac and the development of IH-DTL accelerator are presented. | Yin Xuejun Yuan Youjin Xia Jiawen Zhang Xiaohu Du Heng Li Zhongshan Li Xiaoni Qiao Jian Xu Zhe Cong Yan Wang Haoning | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 17 | Resource allocation in OFDMA heterogeneous networks for maximizing weighted sum energy efficiency显示文摘In this paper, a resource allocation algorithm for maximizing the weighted sum energy efficiency(EE) is investigated in orthogonal frequency division multiple access(OFDMA) heterogeneous networks(HetNets). We aim to balance the EE of macro cell and low power nodes by subchannel and power allocations. We formulate the problem as a nonlinear sum-of-ratios programming issue, and guarantee data rate requirements of users by using minimum rate constraints. Due to the nonconvexity of the problem, we develop a heuristic subchannel assignment algorithm, and then solve the power allocation problem by parameterized transformations and a first-order approximation based on an iterative algorithm. Numerical results illustrate the convergence and the effectiveness of the proposed algorithm. | Xiaoming WANG Fuchun ZHENG Xia JIA Xiaohu YOU | 2017 | Science China(Information Sciences)2017，60，6： | 0 |
| 18 | Electromagnetic anisotropic homogeneous model for eddy-current field in single-phase wound core显示文摘The analysis of the eddy-current field in the wound core widely used in the field of transformer energy conservation is taken as the theme.Adopting the homogenisation idea to consider the unique geometry of the wound core and features of its equivalent multi-stage circular cross-section magnetic boundary,a homogeneous model consisting of a columnar material with continuous homogeneous electromagnetic anisotropy is established by deriving the Maxwell equations of the magnetic quasi-static field in the columnar coordinate system.Finally,a homogeneous fine element model for the eddycurrent field in the wound core is established and the accuracy of the model has been verified by the test platform.The result shows that the homogeneous model can be effectively used for the analysis of the eddy-current field in the wound core,and the error of calculating the eddy-current loss under different excitation conditions is less than 6%under the premise of extremely saving the engineering calculation cost,which will help improve the operational performance of the wound core and contribute to the energysaving goal of the high-voltage equipment. | Lijun Zhou Woyang Li Yingyi Xia Jiawei Chen Chenqingyu Zhang Xiaohu Cai Lei Guo Dongyang Wang | 2024 | High Voltage2024，9，1： | 0 |
| 19 | How does working from home affect developer productivity?-A case study of Baidu during the COVID-19 pandemic显示文摘Nowadays,working from home(WFH)has become a popular work arrangement due to its many potential benefits for both companies and employees(e.g.,increasing job satisfaction and retention of employees).Many previous studies have investigated the impact of WFH on the productivity of employees.However,most of these studies usually use a qualitative analysis method such as surveys and interviews,and the studied participants do not work from home for a long continuing time.Due to the outbreak of coronavirus disease 2019(COVID-19),a large number of companies asked their employees to work from home,which provides us an opportunity to investigate whether WFH affects their productivity.In this study,to investigate the difference in developer productivity between WFH and working onsite,we conduct a quantitative analysis based on a dataset of developers’daily activities from Baidu Inc.,one of the largest IT companies in China.In total,we collected approximately four thousand records of 139 developers’activities of 138 working days.Out of these records,1103 records are submitted when developers work from home due to the COVID-19 pandemic.We find that WFH has both positive and negative impacts on developer productivity in terms of different metrics,e.g.,the number of builds/commits/code reviews.We also notice that WFH has different impacts on projects with different characteristics including programming language,project type/age/size.For example,WFH has a negative impact on developer productivity for large projects.Additionally,we find that productivity varies for different developers.Based on these findings,we get some feedback from developers of Baidu and understand some reasons why WFH has different impacts on developer productivity.We also conclude several implications for both companies and developers. | Lingfeng BAO Tao LI Xin XIA Kaiyu ZHU Hui LI Xiaohu YANG | 2022 | Science China(Information Sciences)2022，65，4： | 0 |
| 20 | RF and field measurements of the SSC-LINAC RFQ显示文摘The 53.667 MHz continuous-wave heavy ion RFQ has been designed and manufactured for the SSC-LINAC project.This four-rod RFQ accelerates ions with maximum mass to charge ratio of 7 from 3.728 keV/u to 143 keV/u.Measurements have been carried out to check the RF performance of the cavity and the quality of the electric field.The S11 of the power coupler is adjusted to better than-44 dB,and the Q0 of the cavity is 6440.The quality of the electric field is evaluated by the perturbation method.The measurement procedure and data analysis will be discussed in detail.The error due to gravity of the perturbation bead has been corrected by averaging the fields in different quadrants.As a result,the unflatness of the electric field is±2.5%,and the dipole field component distributes from 0%to 20%in different longitudinal positions,which indicates the asymmetry of the quadrupole field.The unflatness of the quadrupole field distribution represents a good agreement with the simulation results.High power RF test and beam commissioning of the RFQ are on schedule in early 2014. | LIU Ge LU YuanRong YIN XueJun ZHANG XiaoHu DU Heng JIANG PeiYong LI ZhongShan LI XiaoNi HE Yuan WANG Zhi GAO ShuLi YANG YaQing ZHU Kun YAN XueQing CHEN JiaEr YUAN YouJin XIA JiaWen ZHAO HongWei | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 0 |
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