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66篇 您的检索式:作者名="Xiao Kan"
    题名 作者 年代 出处 被引量
1Robust Position Anti-Interference Control for PMSM Servo System With Uncertain Disturbance显示文摘Aiming to suppress the influence of uncertain disturbances in the drive control of permanent magnet synchronous machines(PMSM),such as the parameter uncertainties and load disturbance,a robust anti-interference control for the angular position tracking control of a PMSM servo system has been proposed in this paper.During the position tracking,uncertain system disturbances being regarded as a lumped unknown term will be online observed by a nonlinear disturbance observer(NDOB),of which the influence will consequently be counteracted by a robust backstepping compensator(RBC).The asymptotical stability of proposed control scheme is analyzed and designed according to the Lyapunov stability criterion,and its convergence against the system uncertain disturbance is verified on a prototype PMSM servo platform and shows good performance in rotor angular position tracking and anti-interference.Longfei Li Jie Xiao Yun Zhao Kan Liu Xiaoyan Peng Haozhe Luan Kaiqing Li 2020CES Transactions on Electrical Machines and Systems2020,4,2:13
2Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer显示文摘Xin Tian Baofa Sun Chuanyuan Chen Chunchun Gao Ji Zhang XingYu Lu Linchen Wang Xiangnan Li Yurong Xing Ruijuan Liu Xiao Han Zheng Qi Xiaojian Zhang Chuan He Dali Han Yun-Gui Yang Quancheng Kan 2018Cell Research2018,28,5:12
3Science and Prediction of Heavy Rainfall over China:Research Progress since the Reform and Opening-Up of New China显示文摘This paper reviews the major progress on development of the science and prediction of heavy rainfall over China since the beginning of the reform and opening-up of new China(roughly between 1980 and 2019).The progress of research on the physical mechanisms of heavy rainfall over China is summarized from three perspectives:1)the relevant synoptic weather systems,2)heavy rainfall in major sub-regions of China,and 3)heavy rainfall induced by typhoons.The development and application of forecasting techniques for heavy rainfall are summarized in terms of numerical weather prediction techniques and objective forecasting methods.Greatly aided by the rapid progress in meteorological observing technology and substantial improvement in electronic computing,studies of heavy rainfall in China have advanced to investigating the evolution of heavy-rain-producing storms and observational analysis of the cloud microphysical features.A deeper and more systematic understanding of the synoptic systems of importance to the production of heavy rainfall has also been developed.Operational forecast of heavy rainfall in China has changed from subjective weather event forecasts to a combination of both subjective and objective quantitative precipitation forecasts,and is now advancing toward probabilistic quantitative precipitation forecasts with the provision of forecast uncertainty information.Yali LUO Jisong SUN Ying LI Rudi XIA Yu DU Shuai YANG Yuanchun ZHANG Jing CHEN Kan DAI Xueshun SHEN Haoming CHEN Feifan ZHOU Yimin LIU Shenming FU Mengwen WU Tiangui XIAO Yangruixue CHEN Huiqi LI Mingxin LI 2020Journal of Meteorological Research2020,34,3:10
4Neural endoscopic assisted micro-invasive management of Chiari I malformation显示文摘背景以便为 Chiari 的管理做以后的窝解压缩我简单、不太侵略的畸形性当使用直接可视化时,一个新奇完全内视镜的过程为 Chiari 的解压缩被采用了畸形性类型我。这研究的目的是为 Chiari 类型介绍神经的内视镜的以后的窝解压缩和地图集 laminectomy 我有 Chiari 的 21 个病人打的 patients.Methods 我经历了神经的内视镜的以后的窝解压缩和地图集 laminectomy。我们为神经的内视镜的以后的窝解压缩和地图集 laminectomy 描述了过程。在这个系列的所有病人除了 syringomyelia 在孔大酒瓶下面表明了小脑的扁桃腺形成疝。在考察学习的所有病人象 3 月的手术后的 MRI 一样经历了外科手术前的 MRI。改变,但是通常是的另外的后续 MRI 在外科以后重复了 12 个月到 18 个月。手术后的 MRI 研究回顾地被考察,与外科手术前的 studies.Results 相比,所有病人显示出临床的改进,并且任何一个都没有任何复杂并发症。有 syringomyelia 的病人完全有症状消失。十一个病人(52.4%) 在后续时期期间在 syringomyelia (减少的尺寸或决定) 经历了 X 光线照相术的改进。九个病人(42.8%) 表明了减少的鸣管尺寸,(19%) 四表明了解决的鸣管。有征兆的 syringomyelia 的 15 个病人,(73.3%) 11 经历了征兆的改进。症状改进的中部的时间是在外科以后的四个月。显示的外科的 MRI 考试完成的波斯特和孔大酒瓶 region.Conclusions 内诊镜 atlanto 枕骨的解压缩外科的足够的解压缩是一个创新、安全、有效的外科的过程。它与传统的外科相比有类似的结果,然而与是最小的增加的优点侵略,有更少复杂并发症,对枕骨的多骨的结构的稳定性的减少的影响,和更快的恢复以及减少的医院停留和开销。DENG Kan LI Yong-ning LI Gui-lin GAO Jun YANG Zhong DI Xiao WANG Ren-zhi 2010Chinese Medical Journal2010,,14:7
5Ecological vulnerability analysis of Tibetan towns with tourism-based economy: a case study of the Bayi District显示文摘This paper provides a generalizable mode for the ecological vulnerability evaluation for tourism planning and development in high mountain areas.The Bayi District located in southeastern Tibet is taken as a typical town to study the conflict between the protection of natural ecological environment and the exploitation of tourism resources. Based on the Sensitivity-Recovery-Pressure(SRP) framework, a set of vulnerability evaluation systems for plateau tourism regions were developed. The spatial principal component analysis(SPCA), remote sensing and GIS technologies were integrated to apply for spatial quantification of evaluation index system. The ecological vulnerability of the Bayi District was divided into five levels: potential, mild, moderate,severe, and extreme, and our results showed that significantly severe and extreme vulnerability areas were mainly distributed throughout the southwestern and central northern alpine pasture and glacial zones.Potential and mild vulnerability areas were mainly distributed in the vicinity of the Yarlung Zangbo River tributary basin. Then three tourism development and environmental protection zones were classified and appropriate measures for the protection were proposed. It also provides a reference for the spatial distribution of a range of areas that require different protection measures according to ecological vulnerability classification.KAN Ai-ke LI Guo-qing YANG Xiao ZENG Ye-long TESREN Luobu HE Jie 2018Journal of Mountain Science2018,15,5:7
6Strabismus surgery distribution during 10-year period in a tertiary hospital显示文摘Jiao Yonghong Zhu Yunting Zhou Zhen Jie Ying Wang Jinghui Lu Wei Wu Xiao Kan Mengmeng Zhao Guohong 2014Chinese Medical Journal2014,,16:5
7Reactive mesoporous silica nanoparticles loaded with limonene for improving physical and mental health of mice at simulated microgravity condition显示文摘Astronauts are under high stress for a long time because of the microgravity condition,which leads to anxiety,affects their learning and memory abilities,and seriously impairs the health of astronauts.Aromatherapy can improve the physical and mental health of astronauts in a way that moisturizes them softly and silently.However,the strong volatility of fragrances and inconvenience of aroma treatment greatly limit their application in the field of spaceflight.In this study,reactive mesoporous silica nanoparticles were prepared to encapsulate and slowly release limonene.The limonene loaded nanoparticles were named limonene@mesoporous silica nanoparticles-cyanuric chloride(LE@MSNs-CYC).LE@MSNs-CYC were then applied to wallpaper to improve the convenience of aromatherapy.LE@MSNs-CYC could chemically react with the wallpaper,thus firmly adsorbed on the wallpaper.In the following,the mice were treated with hindlimb unloading(HU)to simulate a microgravity environment.The results showed that 28-day HU led to an increase in the level of anxiety and declines in learning,memory,and physical health in mice.LE@MSNs-CYC showed significant relief effects on anxiety,learning,memory,and physical health of HU treated mice.Subsequently,the molecular mechanisms were explored by hypothalamic-pituitary-adrenal axis related hormones,immune-related cytokines,learning,and memory-related neurotransmitters and proteins.Zhiguo Lu Jianze Wang Lina Qu Guanghan Kan Tianlu Zhang Jie Shen Yan Li Jun Yang Yunwei Niu Zuobing Xiao Yinghui Li Xin Zhang 2020Bioactive Materials2020,5,4:5
8Effects of 1-MCP on proline,polyamine,and nitric oxide metabolism in postharvest peach fruit under chilling stress显示文摘Peach(Prunus persica Batsch‘Yuhualu’)fruit are sensitive to chilling injury(CI).Proline,polyamine(PA),and nitric oxide(NO)are important small regulators of various metabolic pathways under chilling stress that mitigate CI.Ethylene is known to promote senescence and CI,while 1-methylcyclopropene(1-MCP)is an antagonist that inhibits the effects of ethylene.However,how1-MCP and ethylene affect proline,PA,and NO levels under chilling stress remains unclear.To address these questions,1-MCP(1μL·L^(−1))and ethylene(1μL·L^(−1))treatments were applied to peach fruit.Fruit were stored at 4°C for 28 d,then moved to 25°C for 3 d immediately after cold storage.Peach fruit exhibited CI symptoms after 7 d of cold storage with enhanced electrolyte leakage and malondialdehyde contents.The 1-MCP treatment significantly(P<0.05)restrained peach CI,and fruit did not exhibit CI symptoms until 14 d of cold storage.Proline and PAs in peach under chilling stress weremostly synthesized from glutamate and arginine,which were catalyzed by1-pyrroline-5-carboxylate synthetase and arginine decarboxylase,respectively.1-MCPtreated fruit exhibited higher proline and PA contents and enhanced chilling tolerance compared to the control,while ethylene-treated fruit had lower proline and PA contents and reduced chilling tolerance.Ethylene-treated fruit,which exhibited more severe CI symptoms compared to the control,had significantly(P<0.05)lower NO contents and NO synthase activities.However,NOmay not be a direct acting factor in 1-MCPinduced chilling tolerance,as 1-MCP-treated fruit had lower NO contents and NO synthase activities compared to the control.In conclusion,proline and PA clearly played direct and important roles in 1-MCP-induced peach chilling tolerance,while NO may not be actively involved.Chunlu Qian Zhengjie Ji Qin Zhu Xiaohua Qi Qianqian Li Jiandong Yin Jun Liu Juan Kan Man Zhang Changhai Jin Lixia Xiao 2021Horticultural Plant Journal2021,7,3:4
9Activity of T Cells Stimulated by Hemagglutinin-neuraminidase of Newcastle Disease Virus in vivo显示文摘To investigate the stimulated activity of T cells and the anti-tumor properties of hemagglutinin-neuraminidase(HN) of Newcastle disease virus(NDV) strain Changchun(NDVcc), the expression of HN gene in hepatoma cells(human HepG-2 and mouse H22 cells) infected with the recombinant adenovirus(Ad-HN) was identified by Western blot analysis and flow cytometry. Sialidase activity of NDVcc HN expressed by Ad-HN was assayed by the periodate-resorcinol method. The in vivo anti-tumor effects of NDVcc HN were evaluated in the H22 solid tumor model. Regional lymph nodes of the mouse model treated with Ad-HN were removed to harvest T lymphocytes and evaluating the specific cytotoxicity of cytotoxic T lymphocyte(CTL) and natural killer(NK) cells by an L-lactate dehydrogenase(LDH) assay, in the mean time, the secretion of cytokines was analyzed by enzyme linked immunosorbent assays(ELISA). The results show that NDVcc HN was effectively expressed by Ad-HN in HepG-2 and H22 cells. The sialidase activity assay showed that Ad-HN significantly reduced sialic acid level of the hepatoma cells compared with the cells infected the empty adenovirus vector(Ad-mock). When treated with Ad-HN, the growth of subcutaneous H22 primary tumors in C57BL/6 mice was suppressed, and the mean mice survival increased. In addition, the treatment of Ad-HN elicited strong NK and CTL responses, and high levels of Th1 cytokines, such as IL-2 and IFN-γ. In conclusion, NDVcc HN effectively elicits T cell-mediate anti-tumor cytotoxicity via sialidase activity and may be a novel strategy for cancer immunotherapy.PIAO Bing-guo LI Xiao SUN Li-li KAN Shi-fu LIU Lei HUANG Hai-yan YANG Guo-hua WANG Yu-hang WANG Zhuo-yue SUN Jiu-hua PIAO Yun-feng JIN Ning-yi 2011Chemical Research in Chinese Universities2011,27,3:3
10New WHO global air quality guidelines help prevent premature deaths in China显示文摘The air quality guidelines (AQGs) issued by the World Health Organization (WHO) in 2005 are key references for the National Ambient Air Quality Standards (NAAQSs) in China.On 22September 2021,the WHO issued new AQGs (NAQGs)[1],which propose more stringent targets to control exposure to multiple air pollutants,including fine particulate matter (PM_(2.5)) and ozone (O_(3)),to which,in 2019,451 million premature deaths,globally,were attributable [2].Tao Xue Guannan Geng Xia Meng Qingyang Xiao Yixuan Zheng Jicheng Gong Jun Liu Wei Wan Qiang Zhang Haidong Kan Shiqiu Zhang Tong Zhu 2022National Science Review2022,9,4:3
11Anti-tumor Effects of a Recombinant Fowlpox Virus Expressing Apoptin on Human Cervical Carcinoma in Vivo and in Vitro显示文摘Apoptin is a chicken anemia virus-derived,p53-independent,bcl-2-insensitive apoptotic protein with the ability to specifically induce apoptosis of various human tumor cells,but not of normal diploid cells.To explore the application of apoptin in tumor gene therapy,we used a recombinant fowlpox virus expressing apoptin protein (vFV-Apoptin) to investigate the anti-tumor effectes of vFV-Apoptin on human cervical carcinoma(HeLa) cells in vivo and in vitro through 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide(MTT) assay,acridine orage/ethidium bromide(AO/EB) and annexin V staining test,respectively.The results show that vFV-Apoptin inhibites the proliferation of HeLa cells in vitro through inducing the apoptosis of HeLa cells,and the inhibition effect of vFV-Apoptin has a dose-effect and time-effect relationship.The results of animal models show that vFV-Apoptin significantly inhibits tumor growth,extends the lifespan of animals and improves the mean survival.Experimental results indicate that vFV-Apoptin has a potential application in the tumor gene therapy.ZHU Ji-hong LI Xiao SUN Li-li ZHANG Mu-chun KAN Shi-fu LIU Lei HUANG Hai-yan YANG Guo-hua PIAO Bing-guo JIN Ning-yi 2011Chemical Research in Chinese Universities2011,27,4:3
12A new electroplated Ir/Ir(OH)_x pH electrode and its application in the coastal areas of Newport Harbor, California显示文摘Resulting from the rising levels of atmospheric carbon, ocean acidification has become a global problem. It has significant impacts on the development, survival, growth and physiology of marine organisms. Therefore, a highprecision sensor is urgently needed to measure the pH of sea-water. Iridium wire with a diameter of 0.25 mm is used as the substrate, and an Ir/Ir(OH)_x pH electrode is prepared by a one-step electrochemical method in a Li OH solution at the room temperature. A scanning electron microscope(SEM) observation reveals that it is coated with nanoscale particles. In laboratory tests, the electrode exhibits a very promising pH response, with an ideal Nernst slope(56.14–59.52), fast response, good stability and long life-span in tested pH buffer solutions. For a sea trial,four pH electrodes and one Ag/Ag Cl reference electrode are integrated with a self-made chemical sensor, and a profile detection of nearly 70 m is implemented near Newport Harbor, California on August 3, 2015. The results reflect that the pH value measured by the sensor is very close to the data given by Sea-Bird 911 plus CTD, with a difference value ranging from 0.000 075 to 0.064 719. And the sensor shows a better data matching degree in 0–40m water depth. In addition, the high precision and accuracy of the sensor make it possible to use in the ocean observation field.ZHANG Xiao YE Ying KAN Yating HUANG Yuanfeng JIA Jianjun ZHAO Yue CHEN Chen-Tung Arthur QIN Huawei 2017Acta Oceanologica Sinica2017,36,5:2
13Expression and Characterization of a Recombinant Truncated Capsid Protein of Hepatitis E Virus in Pichia pastoris显示文摘Hepatitis E is an enterically transmitted viral disease caused by infection with hepatitis E virus(HEV).HEV is a nonenveloped virus that has been classified in the family of Caliciviridae.The virus appears to be a polyadenylated,positive-stranded RNA virus with three major open reading frames(ORFs).The capsid protein of HEV is encoded by the open reading frame 2(ORF2).We attempted to produce a truncated capsid protein,designed p293,in Pichia pastoris.The p293 gene encoding amino acids(aa) 382-674 of HEV ORF2 was designed based on the full length of HEV ORF2,cloned into the yeast vector pPIC9K,and expressed in P.pastoris strain GS115.SDS-PAGE and Western blotting demonstrated that the recombinant protein p293 could well be expressed in P.pastoris.Under optimized conditions (culture medium pH,6.0―6.5;methanol concentration added daily,3.0%;inoculum density,OD600=60;induction time point,72―96h),the yield of soluble p293 was approximately 80 mg/L.We also observed p293 secretory expressed in P.pastoris to be 30 nm viral like particles by using electron microscopy.These results show that the p293 may has utility in the analysis of cell specific factors in the protein processing and assembly of HEV,and serve as a useful antigen for both diagnostic and vaccine purposes.YANG En-cheng CHI Bao-rong LI Xiao LIU Yan GAO Peng JIA Peng KAN Shi-fu WEN Zhong-mei WANG Wan JIN Ning-yi 2010Chemical Research in Chinese Universities2010,26,2:2
14A novel HBV genotypes detecting system combined with microfluidic chip, loop-mediated isothermal amplification and GMR sensors显示文摘Xiao Zhi Min Deng Hao Yang Guo Gao Kan Wang Hualin Fu Yixia Zhang Di Chen Daxiang Cui 2014Biosensors and Bioelectronics2014,,:2
15Influence of Environmental Conditions on the Sound Velocity Ratio of Seafloor Surficial Sediment显示文摘In this work,we investigated the influences of salinity,temperature,and hydrostatic pressure on the acoustics of seafloor surficial sediment by theoretically and experimentally analyzing the sound velocity ratio of the seafloor sediment to the bottom sea-water in typical environmental conditions.Temperature-and pressure-controlled experiments were conducted to examine the charac-teristics of the sound velocity ratio,the results of which agree with the theoretical analysis using the effective density fluid model.Of the three environmental factors considered,the sound velocity ratio was found to be sensitive to temperature and pressure but not to salinity,with the sound velocity ratio decreasing with temperature and hydrostatic pressure.With respect to surficial sediments,pore water plays a key role in the sound velocity ratio of sediment influenced by different environmental factors.The sound velocities of different types of sediments(sandy,silty,and clayey)change similarly with temperature,but change slightly differently with hydro-static pressure.The influence of environmental factors on the sound velocity ratio of seafloor sediment is independent of the detec-tion frequency.The results show that the sound velocity ratio can change up to 0.0008 per℃ when the temperature ranges from 2℃ to 25℃ and up to 0.00064MPa−1 when the seawater depth pressure ranges from 0MPa to 40MPa.ZOU Dapeng ZENG Ziwen KAN Guangming LIU Wei XIAO Tibing 2021Journal of Ocean University of China2021,20,3:2
16GmFtsH25 overexpression increases soybean seed yield by enhancing photosynthesis and photosynthates显示文摘Increasing plant photosynthetic capacity is a promising approach to boost yields,but it is particularly challenging in C3crops,such as soybean(Glycine max(L.)Merr.).Here,we identified GmFtsH25,encoding a member of the filamentation temperature-sensitive protein H protease family,as a major gene involved in soybean photosynthesis,using linkage mapping and a genome-wide association study.Overexpressing GmFtsH25 resulted in more grana thylakoid stacks in chloroplasts and increased photosynthetic efficiency and starch content,while knocking out GmFtsH25 produced the opposite phenotypes.GmFtsH25 interacted with photosystem I light harvesting complex 2(GmLHCa2),and this interaction may contribute to the observed enhanced photosynthesis.GmFtsH25 overexpression lines had superior yield traits,such as yield per plant,compared to the wild type and knockout lines.Additionally,we identified an elite haplotype of GmFtsH25,generated by natural mutations,which appears to have been selected during soybean domestication.Our study sheds light on the molecular mechanism by which GmFtsH25 modulates photosynthesis and provides a promising strategy for improving the yields of soybean and other crops.Li Wang Yuming Yang Zhongyi Yang Wenlong Li Dezhou Hu Huilian Yu Xiao Li Hao Cheng Guizhen Kan Zhijun Che Dan Zhang Hengyou Zhang Hui Wang Fang Huang Deyue Yu 2023Journal of Integrative Plant Biology2023,65,4:2
17Near-zero-dispersion soliton and broadband modulational instability Kerr microcombs in anomalous dispersion显示文摘The developing advances of microresonator-based Ker cavity solitons have enabled versatile applications ranging from communication,signal processing to high-precision measurements.Resonator dispersion is the key factor determining the Kerr comb dynamics.Near the zero group-velocity-dispersion(GVD)regime,low-noise and broadband microcomb sources are achievable,which is crucial to the application of the Kerr soliton.When the GVD is almost vanished,higher-order dispersion can significantly affect the Kerr comb dynamics.Although many studies have investigated the Kerr comb dynamics near the zero-dispersion regime in microresonator or fiber ring system,limited by dispersion profles and dispersion perturbations,the near-zero-dispersion soliton structure pumped in the anomalous dispersion side is still elusive so far.Here,we theoretically and experimentally investigate the microcomb dynamics in fiber-based Fabry-Perot microresonator with ultra-small anomalous GVD.We obtain 2/3-octave-spaning microcombs with~10 GHz spacing,>84 THz span,and>8400 comb lines in the modulational instability(MI)state,without any external nonlinear spectral broadening.Such widely-spanned Ml combs are also able to enter the soliton state.Moreover,we report the first observation of anomalous-dispersion based near-zero-dispersion solitons,which exhibits a local repetition rate up to 8.6 THz,an individual pulse duration<100 fs,a span>32 THz and>3200 comb lines.These two distinct comb states have their own advantages.The broadband MI combs possess high conversion efficiency and wide existing range,while the near-zero-dispersion soliton exhibits relatively low phase noise and ultra-high local repetition rate.This work complements the dynamics of Kerr cavity soliton near the zero-dispersion regime,and may stimulate cross-disciplinary inspirations ranging from dispersion-controlled microresonators to broadband coherent comb devices.Zeyu Xiao Tieying Li Minglu Cai Hongyi Zhang Yi Huang Chao Li Baicheng Yao Kan Wu Jianping Chen 2023Light(Science & Applications)2023,12,2:2
18Quantitative analysis of secretome from adipocytes regulated by insulin显示文摘Adipocyte 是经由肽和蛋白质的分泌物在另外的机关涉及精力的存储和版本,而且在精力新陈代谢的规定的不仅一个中央播放器。在胰岛素抵抗和类型的致病期间 2 糖尿病, adipocytes 受到胰岛素的增加的层次,它可以在 adipokines 的分泌物上有主要影响。我们承担了劈得开的编码同位素的亲密关系标签(cICAT ) ,没有标签的 quantitation 来临鉴别是差别的能分泌的因素由 3T3-L1 adipocytes 藏匿了与或没有胰岛素处理并且确定。cICAT 和没有标签的结果的联合,有 317 蛋白质,预言或注解同样能分泌的蛋白质。在这些能分泌的蛋白质之中, 179 蛋白质和 53 蛋白质分别地显著地起来调整、下面调整。77 的一个总数报导 adipokines 在我们的学习被确定,例如 adiponectin,组织蛋白酶 D, cystatin C, resistin,和 transferrin。这些 adipokines 的西方的污点分析从集体 spectrometry 证实了量的结果,并且由增加胰岛素剂量揭示了这些蛋白质的个性化的 secreting 模式。另外, 240 蛋白质是在我们的学习,其大多数在胰岛素处理之上起来调整从 3T3-L1 adipocytes 分泌了蛋白质最新被识别并且确定。进一步全面的生物信息学分析表明在细胞外的矩阵受体相互作用小径和 glycan 结构降级小径的能分泌的蛋白质由胰岛素刺激是显著地起来调整的。Hu Zhou Yuanyuan Xiao Rongxia Li Shangyu Hong Sujun Li Lianshui Wang Rong Zeng Kan Liao 2009Acta Biochimica et Biophysica Sinica2009,41,11:2
19Comparative Study of the Genetic Diversity, Antimicrobial Resistance, and Pathogenicity of Aeromonas Isolates from Clinical Patients and Healthy Individuals显示文摘Objective This study was performed to compare the genetic diversity,virulence,and antimicrobial resistance of Aeromonas strains isolated from patients and healthy individuals.Methods A total of 38 clinical strains and 19 strains from healthy individuals were isolated from the samples collected in Ma’anshan City,Anhui Province.Their taxonomy was investigated using concatenated gyrB-cpn60 sequences,and their resistance to 12 antibiotics was evaluated.The pathogenicity of these strains was examined through beta-hemolysis,protease activity,and virulence gene assays.Results The 57 Aeromonas strains were divided into 55 sequence types.Of these types,21 were novel,suggesting that their genetic diversity was high.These Aeromonas isolates could be divided into 7 species,and the positive rates of beta-hemolysis and protease activity were 49.1%and 73.7%,respectively.The detection rate of clinical patients in terms of beta-hemolysis and protease activity was higher than that of healthy individuals.Among the four most common Aeromonas strains,A.dhakensis had the highest detection rate of virulence genes.The multidrug resistance rate of the clinical isolates was much higher than that of the strains isolated from healthy individuals.Conclusions The taxonomy,virulence properties,and antibiotic resistance of Aeromonas isolates from patients differ from those of the isolates from healthy individuals.MENG Shuang DU Xiao Li WANG Yong Lu QU Feng Tian XIE Gui Lin ZHOU Hai Jian HU Jin Rui QIN Zheng WANG Yue KAN Biao CUI Zhi Gang 2021Biomedical and Environmental Sciences2021,34,6:2
20Temperature Profile of Black Hole Accretion Disc with Magnetic Coupling显示文摘Two new mapping relations between the angular coordinate on the black hole (BH) horizon and radialcoordinate on the disc are given according to the requirement of general relativity and Maxwell's equations, and theeffects of magnetic coupling (MC) on temperature of accretion disc are investigated by comparing with pure accretion.It is shown that the MC effects on the temperature profile are related intimately to the BH spin, and the influenceon the peak value of disc temperature based on the modified mapping relations is not as great as that based on thelinear mapping.The peak value and the corresponding radius of peak value ring of disc temperature do not increasemonotonically as the increasing spin of BH, each containing a maximum for the fast-spinning BH. The value ranges ofthe bolometric luminosity and color temperature of the disc are both extended by the MC effects.LEI Wei-Hua WANG Ding-Xiong XIAO Kan 2002Communications in Theoretical Physics2002,,8:1
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