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| 1 | Ammonium removal pathways and microbial community in GAC-sand dual media filter in drinking water treatment显示文摘A GAC-sand dual media filter(GSF) was devised as an alternative solution for drinking water treatment plant to tackle the raw water polluted by ammonium in place of expensive ozone-GAC processes or bio-pretreatments.The ammonium removal pathways and microbial community in the GSFs were investigated.The concentrations of ammonium,nitrite and nitrate nitrogen were monitored along the filter.Total inorganic nitrogen(TIN) loss occurred during the filtration.For 1 mg ammonium removal,the TIN loss was as high as 0.35 mg,DO consumption was 3.06 mg,and alkalinity consumption was 5.55 mg.It was assumed that both nitrification and denitrification processes occur in the filters to fit the TIN loss and low DO consumption.During the filtration,nitritation,nitrification and nitritation-anaerobic ammonium oxidation processes probably occur,while traditional nitrification and denitrification and simultaneous nitrification and denitrification processes may occur.In the GSFs,Nitrosomonas and Nitrospira are likely to be involved in nitrification processes,while Novosphingobium,Comamonadaceae and Oxalobacteraceae may be involved in denitrification processes. | Shuo Feng Shuguang Xie Xiaojian Zhang Zhiyu Yang Wei Ding Xiaobin Liao Yuanyuan Liu Chao Chen | 2012 | Journal of Environmental Sciences2012，24，9： | 14 |
| 2 | N-doped defective carbon with trace Co for efficient rechargeable liquid electrolyte-/all-solid-state Zn-air batteries显示文摘Simple synthesis of multifunctional electrocatalysts with plentiful active sites from earth-abundant materials is especially fascinating. Here, N-doped defective carbon with trace Co(1.5 wt%) was prepared via a scalable one pot solid pyrolysis process. The sample exhibits efficient bifunctional OER/ORR activity in alkaline, mainly ascribed to the unique micro-mesoporous structure(1–3 nm), high population of graphitic-N doping(up to 49.0%), abundant defects and the encapsulated Co nanoparticles with graphitized carbon. The according rechargeable liquid Zn-air batteries showed excellent performance(maximum power density of 154.0 mW cm^(-2); energy density of 773 Wh kg^(-1) at 5 mA cm^(-2) and charging-discharging cycling stability over 100 cycles). As a proof-of-concept, the flexible, rechargeable all-solid-state Zn-air batteries were constructed, and displayed a maximum power density as high as 45.9 mW cm^(-2), among the top level of those reported previously. | Zhiyan Chen Qichen Wang Xiaobin Zhang Yongpeng Lei Wei Hu Yao Luo Yaobing Wang | 2018 | Science Bulletin2018，63，9： | 14 |
| 3 | BMP2 and VEGF promote angiogenesis but retard terminal differentiation of osteoblasts in bone regeneration by up-regulating Idl显示文摘不适当的 vascularization 限制骨头缺点的修理。以便改进 angiogenesis 并且加速成骨,有在骨头新生的基因修正的 co 有教养的房间的协同在这研究被调查。Endothelial 祖先房间(EPC ) 和骨头髓干细胞(BMSC ) 是有脉管的 endothelial 生长因素(VEGF ) 和骨头的基因的 transfected 形态基因的蛋白质 2 (BMP2 ) 由侵入人体气管粘膜的病菌分别地。co 有教养的房间,包括 BMSC + EPC, Ad-BMP2BMSC + EPC, BMSC + Ad-VEGFEPC,和 Ad-BMP2BMSC + 指定 Ad-VEGFEPC 组织为四个组,在 alginate 胶化上被播种然后肌内地植入进老鼠在 angiogenesis 和成骨上评估效果。VEGF 和 BMP2 能导致禁止者的 overexpression DNA 有约束力 1 (Id1 ) 显著地在 vitro 和增加支持了试管形成的基因在在培植以后的 Ad-BMP2BMSC + Ad-VEGFEPC 组的血容器的数量。不过, Id1 的 overexpression 延迟了造骨细胞和骨头形成的终端区别。后来,在 transcriptional 水平,钙小瘤,和碱的磷酸酶(高山) 活动的 osteogenic 基因表示证明渐渐的减少和最新形成的成骨区域的数量在 Ad-BMP2BMSC + Ad-VEGFEPC 组展出了小增加。这发现建议在 VEGFEPC 和 BMP2BMSCs 的 Id1 表示的一条平衡规定可能对为骨头新生的基于房间、基于基因的途径批评。 | Xiaobin Song Shaohua Liu Xun Qu Yingwei Hu Xiaoying Zhang Tao Wang Fengcai Wei | 2011 | Acta Biochimica et Biophysica Sinica2011，43，10： | 13 |
| 4 | Validation of dynamic cavitation model for unsteady cavitating flow on NACA66显示文摘Unsteady cavitating flow is extremely complicated and brings more serious damages and unignorable problems compared with steady cavitating flow.CFD has become a practical way to model cavitation;however,the popularly used full cavitation model cannot reflect the pressure-change that the bubble experiences during its life path in the highly unsteady flow like cloud cavitating.Thus a dynamic cavitation model(DCM)is proposed and it has been considered to have not only the first-order pressure effects but also zero-order effect and can provide greater insight into the physical process of bubble producing,developing and collapsing compared to the traditional cavitation model.DCM has already been validated for steady cavitating flow,and the results were reported.Furthermore,DCM is designed and supposed to be more accurate and efficient in modeling unsteady cavitating flow,which is also the purpose of this paper.The basic characteristic of the unsteady cavitating flow,such as the vapor volume fraction distribution and the evolution of pressure amplitude and frequency at different locations of the hydrofoil,are carefully studied to validate DCM.It is found that not only these characteristics mentioned above accord well with the experimental results,but also some detailed transient flow information is depicted,including the re-entrant jet flow that caused the shedding of the cavity,and the phenomenon of two-peak pressure fluctuation in the vicinity of the cavity closure in a cycle.The numerical results validate the capability of DCM for the application of modeling the complicated unsteady cavitating flow. | ZHANG XiaoBin ZHANG Wei CHEN JianYe QIU LiMin SUN DaMing | 2014 | Science China(Technological Sciences)2014，57，4： | 8 |
| 5 | Deep electrical structure of the Sulu orogen and neighboring areas显示文摘Because of the discovery of ultrahigh pressure metamorphic (UHPM) belt beneath the Sulu (Jiangsu Province-Shandong Province) orogen, this area has become a focused subject of current geoscience, as it has a close relationship with the evolution of the orogen and the neighboring North China craton. Probing the deep structure beneath this area would be of great significance for the geological inter- pretation of this issue. In this study, we make an analysis of magnetotelluric (MT) data along a profile across the Sulu orogen to provide evidence of deep structure below this region. The profile begins in west from the North China block, extending in S129oE, across the Tan-Lu fault, Sulu UHPM zone, and Sulu high pressure metamorphic (HPM) zone, and terminates in the Yangtze block in east. We use the nonlinear conjugate gradient method and TE-TM combined mode to perform inversion and interpreta- tion of the MT data, and obtain an electrical structure image above depth of 150 km along the profile. It shows that the structure can be divided into seven sections in lateral direction, between which the electric boundaries coincide well with the major faults, such as the Tan-Lu, Haizhou-Siyang, and Ji- ashan-Xiangshui faults. In vertical direction the electrical structure can be subdivided into six layers of different resistivities. It is noted that there exist high-conductivity areas in crust below the North China block and Yangtze block, while such a feature is not present beneath the Sulu orogen, which is very different from the Dabie orogen. It is also observed that a fairly continuous zone of relatively low-resistivity exists at depths of 50-90 km of the electrical structure image, which is presumably a weak zone in the uppermost mantle. Just below this low-resistivity zone are the relatively high- resis- tivity layer of the North China block, relatively low-resistivity layer of the Sulu orogen, and relatively high-resistivity layer of the Yangtze block, all in the shallow upper mantle, respectively. From the whole 2D electrical structure image, there is no abnormally low-resistivity layer in the shallow upper mantle beneath the Sulu orogen and neighboring areas, indicating that no hot asthenoshperic material asso- ciated with lithospheric thinning exists at present. | XIAO QiBin ZHAO GuoZe WANG JiJun ZHAN Yan CHEN XiaoBin TANG Ji CAI JunTao WAN ZhanSheng WANG LiFeng MA Wei ZHANG JiHong | 2009 | Science China Earth Sciences2009，52，3： | 7 |
| 6 | Endothelial cells modified by adenovirus vector containing nine copies hypoxia response elements and human vascular endothelial growth factor as the novel seed cells for bone tissue engineering显示文摘Vascularization 在为骨头织物工程的新治疗学的策略的发展期间是热点之一,它能减轻 hypoxic 情形并且阻止移植失败。脉管的 endothelial 生长因素(VEGF ) 基因 transfection 使用 recombinant 侵入人体气管粘膜的病菌(广告) 向量能有效地支持 angiogenesis,但是 VEGF 的不受管束的长期的连续表示带安全担心。这里,我们构造了包含 HRE 倡导者和 hVEGF165 基因的九个拷贝的 recombinant 广告向量,它保存了组织缺氧可诱导的 factor-1/hypoxia 反应元素(HIF-1/HRE ) 的氧敏感。在进人的脐的静脉 endothelial 房间(HUVEC ) 的 transfection 以后, hVEGF165 mRNA 和蛋白质层次响应组织缺氧是高得多的,作为分别地由 RT-PCR 和 ELISA 揭示了。而且, Ad-9HRE-hVEGF165 向量有效地在 hypoxic 条件下面支持了增长,移植和 HUVEC 的试管形成。因此,我们相信 Ad-9HRE-hVEGF165 向量能贡献 vascularization 的规定,哪个可以在骨头织物工程期间为 hVEGF165 的表达式的更好的控制提供一条新途径(吗?作者 2017。代表生物化学和房间生物学的研究所由牛津大学出版社出版了,为生物科学的上海研究所,中国科学院。版权所有。为权限,请发邮件:journals.permissions@oup.com。) | Xiaobin Song Liang Shi Lamei Chen Xinyu Liu Xun Qu Ketao Wang Fengcai Wei | 2017 | Acta Biochimica et Biophysica Sinica2017，49，11： | 5 |
| 7 | Exogenous rare earth element-yttrium deteriorated soil microbial community structure显示文摘In this study, we selected yttrium as the representative of REEs to investigate the impacts of exogenous yttrium on soil physicochemical properties and microbiota. The results showed that exogenous yttrium has no significant effect on soil physical properties but a significantly negative impact on soil chemical properties. The results of high-throughput sequencing demonstrate that exogenous yttrium significantly decreases the number of OTUs, ACE, Chao 1, and Shannon indices while increases the Simpson index(P < 0.05), indicating the low soil microbial diversity. The relative abundances of soil microbes are significantly changed at phylum and genus level. Principal component analysis(PCA) showed the significant difference of microbial community between yttrium treatments(YCl_3-250 and YCl_3-500) and non-yttrium treatment(CK) and the similarity of that between YCl_3-250 and YCI_3-500. Proteobacteria and Bacteroidetes are found to be the most tolerant phyla to exogenous yttrium while Verrucomicrobia the most sensitive phylum. Redundancy analysis(RDA) results suggest that exogenous yttrium affects soil microbiota only through changing the soil chemical properties but not soil physical properties, and C/N ratio is the key environmental factor. | Caigui Luo Yangwu Deng Jian Liang Sipin Zhu Zhenya Wei Xiaobin Guo Xianping Luo | 2018 | Journal of Rare Earths2018，36，4： | 5 |
| 8 | Selenium-enriched and ordinary green tea extracts prevent high blood pressure and alter gut microbiota composition of hypertensive rats caused by high-salt diet显示文摘High-salt diet is well recognized as a risk factor for hypertension,and dietary intervention plays a critical role in the prevention of hypertension.The current study investigated the effects of selenium-enriched green tea(Se-GT)and ordinary green tea(GT)on prevention of hypertension of rats induced by high-salt diet,as well as their potential regulatory and mechanism.Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure(BP),activated the phosphoinosmde-3-kinase/protein kinase B(PI3K/Akt)signaling pathway,and regulated the gene expression related to BP,as well as improved the tissue damage like heart,liver,and kidneys.Besides,the key parameters associated with oxidative stress,inflammation and endothelial dysfunction were also altered by GT and Se-GT treatments.Importantly,GT or Se-GT administration adjusted the diversity and composition of the intestinal flora.Moreover,GT and Se-GT supplementations increased the abundance of beneficial bacteria and reduced the abundance of harmful or conditional pathogenic bacteria.More specifically,GT intake specifically and significantly enriched the relative abundance of Paraprevotella and Bacteroides,whereas Se-GT was characterized by specific and significant enrichment for Allobaculum and Bifidobacterium.Our results proved that dietary supplement of GT and Se-GT remarkably improved the vascular functions and effectively prevented tissue damage by regulation of intestinal flora,and thus preventing hypertension induced by high-salt diet. | Meirong Wu Xiaobin Wu Jiangxiong Zhu Fanglan Li Xinlin Wei Yuanfeng Wang | 2022 | Food Science and Human Wellness2022，11，3： | 4 |
| 9 | Experimental study on dynamic gas adsorption显示文摘In order to predict the actual adsorption amount as gas adsorption reaches the equilibrium,this research designed a dynamic gas adsorption experiment under constant temperature and pressure,and also studied the isopiestic adsorption characteristics of coal samples with same quality but different sizes.Through the experiment,the study found the adsorption-time changing relationships under different pressures of four different size samples.After regression analysis,we obtained the functional relationship between adsorption and time.According to this,the research resulted in the actual adsorption amount when gas adsorption reaches the equilibrium.In addition,the current study obtained the relationship between adsorption and pressure as well as the effect of the coal size to the adsorption rate.These results have great theoretical and practical significance for the prediction of gas amount in coal seam and gas adsorption process. | Qin Yueping Wang Yaru Yang Xiaobin Liu Wei Luo Wei | 2012 | International Journal of Mining Science and Technology2012，22，6： | 4 |
| 10 | Yielding behavior of copper nanowire in the presence of vacancies显示文摘In the present research,the measurement fluctuations of mechanical properties in nanowires (NWs) are investigated by using the molecular dynamics simulation.The large numbers of simulations are performed to study the yield behaviors of the NWs.The results have shown that the yield behavior of the smaller diameter NW is more sensitive to the presence of vacancies,and the dispersion of the measured mechanical properties for the small scale NW is larger than that for the large scale NW.Present results have also shown that vacancies escape from the bulk to the free surfaces as a result of high stress applied at the small scale systems similar to the dislocation starvation phenomenon observed in the compression test of nano-pillars,and dislocation nucleation induced by surface defect occurs after the vacancy reaches free surface leading to lower yield strength.Moreover,the strong surface vacancy interactions at the nanoscale level are also investigated. | LIU XiaoMing YANG XiaoBin WEI YueGuang | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，6： | 4 |
| 11 | Monitoring of atmospheric radionuclides from the Fukushima nuclear accident and assessing their impact on Xi'an, China显示文摘Aerosol radionuclides (131I, 134Cs, 137Cs) and gaseous radioactive xenon (133Xe) were monitored at Xi'an, China following the accident at the Fukushima nuclear power plant in March 2011. The additional annual effective dose attributable to the Fukushima emissions was much lower than the public annual effective dose from natural radiation, according to Chinese national standards. The monitoring results were compared with data from other countries as well as with the radionuclide concentrations observed in Xi'an after the Chernobyl nuclear accident in 1986. Possible transport pathways of the released radionuclides from Fukushima to Xi'an were investigated. The occurrence of an anticyclone in the Pacific Ocean region and the extended period over which the radionuclides were released made the determination transport pathways complex, but divergence in the plume and easterly flow evidently brought the initial suite of radionuclides to Xi'an. | LIU LongBo WU Shan CAO JunJi XIE Feng SHI QuanLin ZHANG ChangYun TANG HanBing HE XiaoBin ZHANG Rong CHEN LiYun WEI GuanYi ZHANG ZhiHong ZHANG JiaMei DANG HaiJun | 2013 | Chinese Science Bulletin2013，58，13： | 4 |
| 12 | Disaster Risk Science:A Geographical Perspective and a Research Framework显示文摘In this article,we recall the United Nations’30-year journey in disaster risk reduction strategy and framework,review the latest progress and key scientific and technological questions related to the United Nations disaster risk reduction initiatives,and summarize the framework and contents of disaster risk science research.The object of disaster risk science research is the'disaster system'consisting of hazard,the geographical environment,and exposed units,with features of regionality,interconnectedness,coupling,and complexity.Environmental stability,hazard threat,and socioeconomic vulnerability together determine the way that disasters are formed,establish the spatial extent of disaster impact,and generate the scale of losses.In the formation of a disaster,a conducive environment is the prerequisite,a hazard is the necessary condition,and socioeconomic exposure is the sufficient condition.The geographical environment affects local hazard intensity and therefore can change the pattern of loss distribution.Regional multi-hazard,disaster chain,and disaster compound could induce complex impacts,amplifying or attenuating hazard intensity and changing the scope of affected areas.In the light of research progress,particularly in the context of China,we propose a threelayer disaster risk science disciplinary structure,which contains three pillars(disaster science,disaster technology,and disaster governance),nine core areas,and 27 research fields.Based on these elements,we discuss the frontiers in disaster risk science research. | Peijun Shi Tao Ye Ying Wang Tao Zhou Wei Xu Juan Du Jing'ai Wang Ning Li Chongfu Huang Lianyou Liu Bo Chen Yun Su Weihua Fang Ming Wang Xiaobin Hu Jidong Wu Chunyang He Qiang Zhang Qian Ye Carlo Jaeger Norio Okada | 2020 | International Journal of Disaster Risk Science2020，11，4： | 4 |
| 13 | Heat stress-induced mucosal barrier dysfunction is potentially associated with gut microbiota dysbiosis in pigs显示文摘Heat stress(HS)can be detrimental to the gut health of swine.Many negative outcomes induced by HS are increasingly recognized as including modulation of intestinal microbiota.In turn,the intestinal microbiota is a unique ecosystem playing a critical role in mediating the host stress response.Therefore,we aimed to characterize gut microbiota of pigs’exposure to short-term HS,to explore a possible link between the intestinal microbiota and HS-related changes,including serum cytokines,oxidation status,and intestinal epithelial barrier function.Our findings showed that HS led to intestinal morphological and integrity changes(villus height,serum diamine oxidase[DAO],serum D-lactate and the relative expressions of tight junction proteins),reduction of serum cytokines(interleukin[IL]-8,IL-12,interferongamma[IFN-g]),and antioxidant activity(higher glutathione[GSH]and malondialdehyde[MDA]content,and lower superoxide dismutase[SOD]).Also,16S rRNA sequencing analysis revealed that although there was no difference in microbial a-diversity,some HS-associated composition differences were revealed in the ileum and cecum,which partly led to an imbalance in the production of short-chain fatty acids including propionate acid and valerate acid.Relevance networks revealed that HS-derived changes in bacterial genera and microbial metabolites,such as Chlamydia,Lactobacillus,Succinivibrio,Bifidobacterium,Lachnoclostridium,and propionic acid,were correlated with oxidative stress,intestinal barrier dysfunction,and inflammation in pigs.Collectively,our observations suggest that intestinal damage induced by HS is probably partly related to the gut microbiota dysbiosis,though the underlying mechanism remains to be fully elucidated. | Bing Xia Weida Wu Wei Fang Xiaobin Wen Jingjing Xie Hongfu Zhang | 2022 | Animal Nutrition2022，，1： | 3 |
| 14 | Study on the Source Characteristics of Downhole Airgun with Different Excitation Environments显示文摘The measurement of underground medium variation using a repeated artificial source has gradually become an important goal to pursue. In recent years,we have developed and improved a technology system with large capacity airguns excited in land reservoirs by transplanting marine seismic exploration technology. The excitation effect has a close relationship to airgun capacity,water environment,and excitation conditions. In view that large capacity airgun must be excited without a water environment,we expand the system to use in downhole. Based on the BHS-2200 LL downhole airgun with a capacity of250in3,this paper carries out a comparative analysis on the characteristics of an airgun source excited in 0. 2m- and 5. 0m-diameter wells,and the results show that:( 1) The dominant frequency of the airgun signal excited in a 5. 0m well is mainly from 10 Hz to40Hz,lower than that in a 0. 2m well,and the larger body of water is good for bubble oscillation.( 2) In terms of exciting energy,the signal excited in a 5. 0m well has stronger energy than in a 0. 2m well,with a difference of 1 order in magnitude,and the signal can be detected up to 9km excited in a 5. 0m well with a single shot.( 3) The airgun signal has good repeatability in both excitation wells. The downhole airgun excitation technology system has potential application in dynamic monitoring near a fault zone with a small scale range, exploration of oil and mineral resources, and modern urban geophysical environment. | Yang Wei Wang Baoshan Liu Zhengyi Yang Jun Li Xiaobin Chen Yong | 2016 | Earthquake Research in China2016，30，3： | 2 |
| 15 | Carbon emissions induced by farmland expansion in China during the past 300 years显示文摘Scientific assessment of the accounting over carbon in the terrestrial ecosystem in the process land use/land cover changes caused by human activities will help reduce the uncertainty in estimating carbon emissions from the terrestrial ecosystem. This study employs a bookkeeping model to estimate the carbon emissions from farmland reclamation in China during the past 300 years based on the annual rate of land use changes(derived from historical natural vegetation, farmland data), preset carbon density and coefficients of disturbance curves. We find out that:(1) there was a net increase of 79.30×10~4km^2 in national farmland; about 65% of reclaimed farmland had been forest land and 26% of that had been grass land previously;(2) the total amount of carbon emissions from farmland expansion in China had been between 2.94 and 5.61 Pg with the median 3.78 Pg during the past 300 years; specifically, carbon emissions of vegetation were 1.58 Pg while those of soil ranged from 1.35 Pg to4.03 Pg with the median 2.20 Pg;(3) carbon emissions vary greatly across various ecosystems: the emissions were most from forest land, and then grass land and swamps, and the least from shrubs; deserts functioned more likely to be carbon stock in the process of land reclamation;(4) along the time line, carbon emissions had decreased first and then increased while the peak emissions occurred in the first half of 20 th century; and spatially, carbon emissions were most released in Northeast and Southwest China; Northwest China was of the minimum carbon emissions. | Xuhong YANG Xiaobin JIN Xiaomin XIANG Yeting FAN Jing LIU Wei SHAN Yinkang ZHOU | 2019 | Science China Earth Sciences2019，62，2： | 2 |
| 16 | Multi-scale three-dimensional variational data assimilation for high-resolution aerosol observations: Methodology and application显示文摘With an increasing number of air quality monitoring stations installed around the Chinese mainland,high-resolution aerosol observations become available,allowing improvements in air pollution monitoring and aerosol forecasting.However,the multi scales(especially small-scale)information included in high-resolution aerosol observations could not be effectively utilized by the traditional three-dimensional variational method(3DVAR).This study attempted to extend the traditional 3DVAR to a multi-scale 3DVAR with two iteration steps,two-scale-3DVAR(TS-3DVAR),to improve the effectiveness of assimilating high-resolution observations.In TS-3DVAR,the large-scale and small-scale components of observation information were decomposed from the original high-resolution observations using a Gaussian smoothing method and then assimilated using the corresponding large-scale or small-scale background error covariances which were derived from the partitioned background error samples.The data assimilation(DA)analysis field generated by TS-3DVAR is more accurate than 3DVAR in reproducing the field’s multi-scale characteristics,which could thus be used as the initial chemical field of the air quality model to improve aerosol forecasting.Particulate matter with an aerodynamic diameter of less than 2.5μm(PM_(2.5))and 10.0μm(PM_(10)) from the surface air quality monitoring stations from November 01 to November 30,2018 at 00:00 were assimilated daily to verify the effects of TS-3DVAR and 3DVAR on the aerosol analysis and forecast accuracy.The results showed that TS-3DVAR better constrained both large-scale and small-scale,especially the spatial wavelengths in a range of 54-216 km and those above 351 km.The average power spectra of the TS-3DVAR assimilation increment in the two wavelength ranges were 71.70%and 35.33%higher than those of 3DVAR.As a result,the TS-3DVAR was more effective than 3DVAR in improving the accuracy of the initial chemical field,and thereby the forecasting capability for PM_(2.5).In the initial chemical field,the 30-day average correlation coefficient(Corr)of PM_(2.5) of TS-3DVAR was 0.052(6.12%)higher than that of 3DVAR,and the root mean square error(RMSE)of TS-3DVAR was 3.446μg m^(−3)(16.4%)lower than that of 3DVAR.For the forecasting capability for PM_(2.5) mass concentration,the 30-day average Corr of TS-3DVAR during the 0-24 hour forecast period was 0.025(5.08%)higher than that of 3DVAR,and the average RMSE was 2.027μg m^(−3)(4.85%)lower.The positive effect of TS-3DVAR on the improvement of forecasting capability can last for more than 24 h. | Zengliang ZANG Yanfei LIANG Wei YOU Yi LI Xiaobin PAN Zhijin LI | 2022 | Science China Earth Sciences2022，65，10： | 2 |
| 17 | Chronic heat stress induces the disorder of gut transport and immune function associated with endoplasmic reticulum stress in growing pigs显示文摘Although high temperatures influence gut health,data on underlying mechanisms remains scant.Using a pig model,this study performed a global analysis on how chronic heat stress affects the transport and immune function of the gut through transcriptome,proteome,microbial diversity and flow cytometry.A total of 27 pigs with similar body weights were assigned into 3 groups,control(Con)group(23℃),chronic heat stressed(HS)group(33°C),and pair-fed(PF)group,in a controlled environment for 21 days.Our results showed that pigs in the HS group had reduced growth performance and diminished height of ileal villi(P<0.01).Transcriptome and proteome analyses demonstrated notable modification of expression of nutrients and ion transport-related transporters and gut mechanical barrier-related genes by chronic heart stress(P<0.05),suggesting damage of transport functions and the gut barrier.Chronic heat stress-induced endoplasmic reticulum stress also increased the synthesis of misfolded proteins,leading to upregulation of misfolded protein degradation and synthesis,as well as vesicle transport disorder(P<0.05).Energy supply processes were enhanced in the mitochondrion(P<0.05)to maintain biological processes with high energy demands.Furthermore,chronic heat stress activated complement cascade response-related genes and proteins in the gut mucosa(P<0.05).Our flow cytometry assays showed that the proportion of gut lymphocytes(CD4^(+)T cells,T cells,B cells in Peyer’s patch lymphocytes and CD4^(+)CD25^(+)T cells in intraepithelial lymphocytes)were significantly altered in the HS group pigs(P<0.05).In addition,the occurrence of gut microbial dysbiosis in the HS group pigs was characterized by increased potential pathogens(e.g.,Asteroleplasma,Shuttleworthia,Mycoplasma)and suppression of beneficial bacteria(e.g.,Coprococcus and Aeriscardovia),which are associated with gut immune function.Altogether,our data demonstrated that chronic heat stress induced gut transport and immune function disorder associated with endoplasmic reticulum stress in growing pigs. | Shanlong Tang Jingjing Xie Wei Fang Xiaobin Wen Chang Yin Qingshi Meng Ruqing Zhong Liang Chen Hongfu Zhang | 2022 | Animal Nutrition2022，，4： | 2 |
| 18 | MoS2/MnO2 heterostructured nanodevices for electro- chemical energy storage显示文摘 | Xiaobin Liao Yunlong Zhao Junhui Wang Wei Yang Lin Xu Xiaocong Tian Yi Shuang Kwadwo Asare Owusu Mengyu Yan Liqiang Mai | 2018 | Nano Research2018，11，4： | 2 |
| 19 | Rabies Virus Pseudotyped with CVS-N2C Glycoprotein as a Powerful Tool for Retrograde Neuronal Network Tracing显示文摘Efficient viral vectors for mapping and manipulating long-projection neuronal circuits are crucial in structural and functional studies of the brain. The SAD strain rabies virus with the glycoprotein gene deleted pseudotyped with the N2 C glycoprotein(SAD-RV(DG)-N2 C(G)) shows strong neuro-tropism in cell culture, but its in vivo efficiency for retrograde gene transduction and neuro-tropism have not been systematically characterized.We compared these features in different mouse brain regions for SAD-RV-N2 C(G) and two other widely-used retrograde tracers, SAD-RV(DG)-B19(G) and r AAV2-retro. We found that SAD-RV(DG)-N2 C(G) enhanced the infection efficiency of long-projecting neurons by^10 times but with very similar neuro-tropism, compared with SAD-RV(DG)-B19(G). On the other hand, SAD-RV(DG)-N2 C(G) had an infection efficiency comparable with r AAV2-retro, but a more restricted diffusion range, and broader tropism to different types and regions of longprojecting neuronal populations. These results demonstrate that SAD-RV(DG)-N2 C(G) can serve as an effective retrograde vector for studying neuronal circuits. | Xutao Zhu Kunzhang Lin Qing Liu Xinpei Yue Huijie Mi Xiaoping Huang Xiaobin He Ruiqi Wu Danhao Zheng Dong Wei Liangliang Jia Weilin Wang Anne Manyande Jie Wang Zhijian Zhang Fuqiang Xu | 2020 | Neuroscience Bulletin2020，36，3： | 2 |
| 20 | Statistical Analysis of Thunderstorms on the Eastern Tibetan Plateau Based on Modified Thunderstorm Indices显示文摘The Tibetan Plateau, with an average altitude above 4000 m, is the highest and largest plateau in the world. The frequency of thunderstorms in this region is extremely high. Many indices are used in operational forecasting to assess the stability of the atmosphere and predict the probability of severe thunderstorm development. One of the disadvantages of many of these indices is that they are mainly based on observations from plains. However, considering the Plateau's high elevation, most convective parameters cannot be applied directly, or their application is ineffective. The pre-convective environment on thunderstorm days in this region is investigated based on sounding data obtained throughout a five-year period(2006–10).Thunderstorms occur over the Tibetan Plateau under conditions that differ strikingly from those in plains. On this basis,stability indices, such as the Showalter index(including SI and SICCL), and the K index are improved to better assess the thunderstorm environments on the Plateau. Verification parameters, such as the true-skill statistic(TSS) and Heidke skill score(HSS), are adopted to evaluate the optimal thresholds and relative forecast skill for each modified index. Lastly, the modified indices are verified with a two-year independent dataset(2011–12), showing satisfactory results for the modified indices. For determining whether or not a thunderstorm day is likely to occur, we recommend the modified SICCLindex. | YOU Wei ZANG Zengliang PAN Xiaobin ZHANG Lifeng LI Yi | 2015 | Advances in Atmospheric Sciences2015，32，4： | 2 |
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