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138篇 您的检索式:作者名="YANG XiaoBin"
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1Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases显示文摘在各种各样的纸巾的 microRNAs (miRNAs ) 的 Dysregulated 表示与许多疾病被联系了,包括癌症。这里,我们证明 miRNAs 在象老鼠,老鼠,牛的胎儿,小牛,和马那样的人和另外的动物的浆液和血浆是在场的。在浆液的 miRNAs 的层次在一样的种类的个人之中稳定、可再现、一致。采用 Solexa,我们定序健康中国题目的所有浆液 miRNAs 并且分别地在男、女的题目发现超过 100 和 91 浆液 miRNAs。我们也为肺癌症, colorectal 癌症,和糖尿病识别了浆液 miRNAs 的特定的表示模式,提供证据那浆液 miRNAs 为各种各样的疾病包含指纹。癌症特定的浆液 miRNAs 由 Solexa 获得了的二个非小的房间肺进一步在 75 个健康施主和 152 个癌症病人的独立审判被验证,用量的反向的抄写聚合酶链反应试金。通过这些分析,我们断定浆液 miRNAs 能为各种各样的癌症和另外的疾病的察觉用作潜在的 biomarkers。Xi Chen Yi Ba Lijia Ma Xing Cai Yuan Yin Kehui Wang Jig ang Guo Yujing Zhang Jiangning Chen Xing Guo Qibin Li Xiaoying Li Wenjing Wang Yan Zhang Jin Wang Xueyuan Jiang Yang Xiang Chen Xu Pingping Zheng Juanbin Zhang Ruiqiang Li Hongjie Zhang Xiaobin Shang Ting Gong Guang Ning Jun Wang Ke Zen Junfeng Zhang Chen-Yu Zhang 2008Cell Research2008,18,10:975
2Analyses on the tectonic thermal evolution and influence factors in the deep-water Qiongdongnan Basin显示文摘To reveal the tectonic thermal evolution and influence factors on the present heat flow distribution, based on 154 heat flow data, the present heat flow distribution features of the main tectonic units are first analyzed in detail, then the tectonic thermal evolution histories of 20 profiles are reestablished crossing the main deep-water sags with a structural, thermal and sedimentary coupled numerical model. On the basis of the present geothermal features, the Qiongdongnan Basin could be divided into three regions: the northern shelf and upper slope region with a heat flow of 50–70 m W/m2, most of the central depression zone of 70–85 m W/m2, and a NE trending high heat flow zone of 85–105 m W/m2 lying in the eastern basin. Numerical modeling shows that during the syn-rift phase, the heat flow increases generally with time, and is higher in basement high area than in its adjacent sags. At the end of the syn-rift phase, the heat flow in the deepwater sags was in a range of 60–85 m W/m2, while in the basement high area, it was in a range of 75–100 m W/m2. During the post-rift phase, the heat flow decreased gradually, and tended to be more uniform in the basement highs and sags. However, an extensive magmatism, which equivalently happened at around 5 Ma, has greatly increased the heat flow values, and the relict heat still contributes about 10–25 m W/m2 to the present surface heat flow in the central depression zone and the southern uplift zone. Further analyses suggested that the present high heat flow in the deep-water Qiongdongnan Basin is a combined result of the thermal anomaly in the upper mantle, highly thinning of the lithosphere, and the recent extensive magmatism. Other secondary factors might have affected the heat flow distribution features in some local regions. These factors include basement and seafloor topography, sediment heat generation, thermal blanketing, local magmatic injecting and hydrothermal activities related to faulting and overpressure.WANG Zhenfeng SHI Xiaobin YANG Jun HUANG Baojia SUN Zhen WANG Yahui JIANG Haiyan YU Chuanhai YANG Xiaoqiu 2014Acta Oceanologica Sinica2014,33,12:22
3Ammonium removal pathways and microbial community in GAC-sand dual media filter in drinking water treatment显示文摘A GAC-sand dual media filter(GSF) was devised as an alternative solution for drinking water treatment plant to tackle the raw water polluted by ammonium in place of expensive ozone-GAC processes or bio-pretreatments.The ammonium removal pathways and microbial community in the GSFs were investigated.The concentrations of ammonium,nitrite and nitrate nitrogen were monitored along the filter.Total inorganic nitrogen(TIN) loss occurred during the filtration.For 1 mg ammonium removal,the TIN loss was as high as 0.35 mg,DO consumption was 3.06 mg,and alkalinity consumption was 5.55 mg.It was assumed that both nitrification and denitrification processes occur in the filters to fit the TIN loss and low DO consumption.During the filtration,nitritation,nitrification and nitritation-anaerobic ammonium oxidation processes probably occur,while traditional nitrification and denitrification and simultaneous nitrification and denitrification processes may occur.In the GSFs,Nitrosomonas and Nitrospira are likely to be involved in nitrification processes,while Novosphingobium,Comamonadaceae and Oxalobacteraceae may be involved in denitrification processes.Shuo Feng Shuguang Xie Xiaojian Zhang Zhiyu Yang Wei Ding Xiaobin Liao Yuanyuan Liu Chao Chen 2012Journal of Environmental Sciences2012,24,9:14
4Three-dimensional hierarchical Pt-Cu superstructures显示文摘三维(3D ) 层次 Pt-Cu 四角形,高度分叉,并且树枝状的上层建筑被一条灵巧的没有模板的热水的途径综合了,出现生长模式沿着(111, 110 ) ,(111 ) ,并且(100 ) 飞机分别地。这些结构被传播电子显微镜学( TEM )描绘了,X光检查衍射( XRD ),精力散X光检查光谱学( EDX ),诱导地联合的血浆光排放 spectrometry ( ICP-OES )和详细形成机制被开发了,它证明在里面形成的 situ 我<潜水艇class=“ a-plus-plus ”>在 Cu 和磅之间的 2 和流电的代替反应<啜class=“ a-plus-plus ”>4+可以指导这些上层建筑的形成。比较 electrocatalytic 性质为甲醇和乙醇氧化被调查了。由于他们的互连的手臂,足够的吸收地点,和暴露的表面,这些上层建筑展览为甲醇和乙醇的电镀物品氧化提高了 electrocatalytic 性能什么时候与商业 Pt/C 和磅黑色相比。Farhat Nosheen Zhicheng Zhang Guolei Xiang Biao Xu Yong Yang Faisal Saleem Xiaobin Xu Jingchao Zhang Xun Wang 2015Nano Research2015,8,3:14
5State of art on energy management strategy for hybrid-powered unmanned aerial vehicle显示文摘New energy sources such as solar energy and hydrogen energy have been applied to the Unmanned Aerial Vehicle(UAV), which could be formed as the hybrid power sources due to the requirement of miniaturization, lightweight, and environmental protection issue for UAV. Hybrid electrical propulsion technology has been used in UAV and it further enforces this trend for the evolution to the Hybrid-Powered System(HPS). In order to realize long endurance flight mission and improve the energy efficiency of UAV, many researching works are focused on the Energy Management Strategy(EMS) of the HPS with digital simulation, ground demonstration platforms and a few flight tests for the UAV in recent years. energy management strategy, in which off-line or on-line control algorithms acted as the core part, could optimize dynamic electrical power distribution further and directly affect the efficiency and fuel economy of hybrid-powered system onboard.In order to give the guideline for this emerging technology for UAV, this paper presents a review of the topic highlighting energy optimal management strategies of UAV. The characteristics of typical new energy sources applied in UAV are summarized firstly, and then the classification and analysis of the architecture for hybrid power systems in UAV are presented. In the context of new energy sources and configuration of energy system, a comprehensive comparison and analysis for the state of art of EMS are presented, and the various levels of complexity and accuracy of EMS are considered in terms of real time, computational burden and optimization performance based on the optimal control and operational modes of UAV. Finally, the tendency and challenges of energy management strategy applied to the UAV have been forecasted.Tao LEI Zhou YANG Zicun LIN Xiaobin ZHANG 2019Chinese Journal of Aeronautics2019,32,6:11
6Pressure balance and imbalance in the optic nerve chamber: The Beijing Intracranial and Intraocular Pressure (iCOP) Study显示文摘To determine the interdependence of intracranial pressure(ICP) and intraocular pressure(IOP) and how it affects optic nerve pressures, eight normal dogs were examined using pressure-sensing probes implanted into the left ventricle, lumbar cistern, optic nerve subarachnoid space in the left eye, and anterior chamber in the left eye. This allowed ICP, lumbar cistern pressure(LCP), optic nerve subarachnoid space pressure(ONSP) and IOP to be simultaneously recorded. After establishing baseline pressure levels, pressure changes that resulted from lowering ICP(via shunting cerebrospinal fluid(CSF) from the ventricle) were recorded. At baseline, all examined pressures were different(ICP>LCP>ONSP), but correlated(P<0.001). As ICP was lowered during CSF shunting, IOP also dropped in a parallel time course so that the trans-lamina cribrosa gradient(TLPG) remained stable(ICP-IOP dependent zone). However, once ICP fell below a critical breakpoint, ICP and IOP became uncoupled and TLPG changed as ICP declined(ICP-IOP independent zone). The optic nerve pressure gradient(ONPG) and trans-optic nerve pressure gradient(TOPG) increased linearly as ICP decreased through both the ICP-IOP dependent and independent zones. We conclude that ICP and IOP are coupled in a specific pressure range, but when ICP drops below a critical point, IOP and ICP become uncoupled and TLPG increases. When ICP drops, a rise in the ONPG and TOPG creates more pressure and reduces CSF flow around the optic nerve. This change may play a role in the development and progression of various ophthalmic and neurological diseases, including glaucoma.Ruowu Hou Zheng Zhang Diya Yang Huaizhou Wang Weiwei Chen Zhen Li Jinghong Sang Sumeng Liu Yiwen Cao Xiaobin Xie Ruojing Ren Yazhuo Zhang Bernhard A. Sabel Ningli Wang 2016Science China(Life Sciences)2016,59,5:11
7Palladium Nanoparticle-Graphene Hybrids as Active Catalysts for the Suzuki Reaction显示文摘Graphene has been successfully modified with palladium nanoparticles in a facile manner by reducing palladium acetate [Pd(OAc)2] in the present of sodium dodecyl sulfate (SDS), which is used as both surfactant and the reducing agent. The palladium nanoparticle-graphene hybrids (Pd-graphene hybrids) are characterized by high- resolution transmission electron microscopy, atomic force microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and energy dispersive X-ray spectroscopy. We demonstrate that the Pd-graphene hybrids can act as an efficient catalyst for the Suzuki reaction under aqueous and aerobic conditions, with the reaction reaching completion in as little as 5 min. The influence of the preparation conditions on the catalytic activities of the hybrids is also investigated.Yang Li Xiaobin Fan Junjie Qi Junyi Ji Shulan Wang Guoliang Zhang Fengbao Zhang 2010Nano Research2010,3,6:10
8High resolution temperature measurement technique for measuring marine heat flow显示文摘High resolution temperature measurement technique is one of the key techniques for measuring marine heat flow. Basing on Pt1000 platinum resistance which has the characteristics of high accuracy and good stability, we designed a bridge reversal excitation circuit for high resolution temperature measurement. And the deep ocean floor in-situ test results show that: (1) temperature deviation and peak-to-peak resolution of the first version circuit board (V1) are 1.960-1.990 mK and 0.980-0.995 m Kat 1.2-2.7°C, respectively; and temperature deviation and peak-to-peak resolution of the second circuit board (V2) are 2.260mK and 1.130 mK at 1.2-1.3°C, respectively; (2) During the 2012NSFC-IndOcean cruise, seafloor geothermal gradient at Ind2012HF03,-07 and-12 stations (water depth ranges from 3841 to 4541 m) were successfully measured, the values are 59.1,75.1 and 71.6°C/km, respectively. And the measurement errors of geothermal gradient at these three stations are less than 3.0% in terms of the peak-to-peak resolution. These indicate that the high resolution temperature measurement technique based on Pt1000 platinum resistance in this paper can be applied to marine heat flow measurement to obtain high precision geothermal parameters.QIN YangYang YANG XiaoQiu WU BaoZhen SUN ZhaoHua SHI XiaoBin 2013Science China(Technological Sciences)2013,56,7:9
9Performing optical logic operations by a diffractive neural network显示文摘Optical logic operations lie at the heart of optical computing,and they enable many applications such as ultrahighspeed information processing.However,the reported optical logic gates rely heavily on the precise control of input light signals,including their phase difference,polarization,and intensity and the size of the incident beams.Due to the complexity and difficulty in these precise controls,the two output optical logic states may suffer from an inherent instability and a low contrast ratio of intensity.Moreover,the miniaturization of optical logic gates becomes difficult if the extra bulky apparatus for these controls is considered.As such,it is desirable to get rid of these complicated controls and to achieve full logic functionality in a compact photonic system.Such a goal remains challenging.Here,we introduce a simple yet universal design strategy,capable of using plane waves as the incident signal,to perform optical logic operations via a diffractive neural network.Physically,the incident plane wave is first spatially encoded by a specific logic operation at the input layer and further decoded through the hidden layers,namely,a compound Huygens’metasurface.That is,the judiciously designed metasurface scatters the encoded light into one of two small designated areas at the output layer,which provides the information of output logic states.Importantly,after training of the diffractive neural network,all seven basic types of optical logic operations can be realized by the same metasurface.As a conceptual illustration,three logic operations(NOT,OR,and AND)are experimentally demonstrated at microwave frequencies.Chao Qian Xiao Lin Xiaobin Lin Jian Xu Yang Sun Erping Li Baile Zhang Hongsheng Chen 2020Light(Science & Applications)2020,9,1:8
10Spatial-temporal pattern changes of main agriculture natural disasters in China during 1990-2011显示文摘China is a disaster prone country, and a comprehensive understanding of change of disasters is very important for China's agricultural development. In this study, statistical techniques and geographic information system tools are employed to quantify the main agriculture disasters changes and effects on grain production in China during the period of 1990–2011. The results show that China's grain production was severely affected by disasters including drought, flood, hail, frost and typhoon. The annual area covered by these disasters reached up to 48.7×106 ha during the study period, which accounted for 44.8% of the total sown area, and about 55.1% of the per unit area grain yield change was caused by disasters. In addition, all of the disasters showed high variability, different changing trends, and spatial distribution. Drought, flood, and hail showed significantly decreasing trends, while frost and typhoon showed increasing trends. Drought and flood showed gradual changes and were distributed across the country, and disasters became more diversified from north to south. Drought was the dominated disaster type in northern China, while flood was the most important disaster type in the southern part. Hail was mainly observed in central and northern China, and frost was mainly distributed in southern China. Typhoon was greatly limited to the southeast coast. Furthermore, the resilience of grain production of each province was quite different, especially in several major grain producing areas, such as Shandong, Liaoning, Jilin and Jiangsu, where grain production was seriously affected by disasters. One reason for the difference of resilience of grain production was that grain production was marginalized in developed provinces when the economy underwent rapid development. For China's agricultural development and grain security, we suggest that governments should place more emphasis on grain production, and invest more money in disaster prevention and mitigation, especially in the major grain producing provinces.DU Xindong JIN Xiaobin YANG Xilian YANG Xuhong XIANG Xiaomin 2015Journal of Geographical Sciences2015,25,4:8
11Bottom water temperature measurements in the South China Sea,eastern Indian Ocean and western Pacific Ocean显示文摘文章报道了一批新的海底底水温度(BWT)数据,其中南海(SCS)158个站位、东印度洋(EIO)30个站位及西太平洋(WPO)37个站位。基于这批新的BWT数据,获得南海和西太平洋海域底水温度与水深经验关系,可为地球物理和物理海洋提供准确、可靠的海底温度边界。这将有助于海底油气资源调查与评估。同时,这批实测数据表明:1)水深超过3500m的海域,其底水温度在南海约为2.47℃,比东印度洋(~1.34℃)和西太平洋(~1.60℃)稍微偏高。这与大洋传送带模式所预测的情况比较吻合。该模式认为:低温高盐的海水,从北大西洋格陵兰岛和冰岛附近海域下沉到深层,然后向南流动,再与南极洲周围海域的低温高盐海水一同向北进入印度洋和太平洋。而南海是一个相对比较封闭的热带边缘海,其内部海水与印度洋和菲律宾海交换有限,导致海水温度整体高于印度洋和太平洋。2)台西南盆地水深在2700~3000m的部分站位,其底水温高达约3.00℃,明显高于其周边同水深海域底水温度(平均值约为2.33℃)。这可能是台西南盆地海底水热活动导致的结果。3)在东印度洋和西太平洋水深超过4800m海域,底水温度随着水压增大稍有升高,其升高率分别为10.6mK·MPa^(-1)和12.0mK·MPa^(-1)。这与理论估算的深层底水绝热压力温度梯度范围较为吻合。这也意味着东印度洋和西太平洋深层底水,主要由绝热自压作用导致其温度随着深度的增大而升高。YANG Xiaoqiu SHI Xiaobin ZHAO Junfeng YU Chuanhai GAO Hongfang CHEN Aihua LU Yuanzheng CEN Xianrong LIN Weiren ZENG Xin XU Hehua REN Ziqiang ZHOU Shengqi XU Ziying SUN Jinlong KAMIYA Nana LIN Jian 2018热带海洋学报2018,37,5:8
12Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution显示文摘The speed of high-resolution optical imaging has been a rate-limiting factor for meso-scale mapping of brain structures and functional circuits,which is of fundamental importance for neuroscience research.Here,we describe a new microscopy method of Volumetric Imaging with Synchronized on-the-fly-scan and Readout(VISo R)for high-throughput,high-quality brain mapping.Combining synchronized scanning beam illumination and oblique imaging over cleared tissue sections in smooth motion,the VISo R system effectively eliminates motion blur to obtain undistorted images.By continuously imaging moving samples without stopping,the system achieves high-speed 3D image acquisition of an entire mouse brain within1.5 hours,at a resolution capable of visualizing synaptic spines.A pipeline is developed for sample preparation,imaging,3D image reconstruction and quantification.Our approach is compatible with immunofluorescence methods,enabling flexible cell-type specific brain mapping and is readily scalable for large biological samples such as primate brains.Using this system,we examined behaviorally relevant whole-brain neuronal activation in 16 c-Fos-sh EGFP mice under resting or forced swimming conditions.Our results indicate the involvement of multiple subcortical areas in stress response.Intriguingly,neuronal activation in these areas exhibits striking individual variability among different animals,suggesting the necessity of sufficient cohort size for such studies.Hao Wang Qingyuan Zhu Lufeng Ding Yan Shen Chao-Yu Yang Fang Xu Chang Shu Yujie Guo Zhiwei Xiong Qinghong Shan Fan Jia Peng Su Qian-Ru Yang Bing Li Yuxiao Cheng Xiaobin He Xi Chen Feng Wu Jiang-Ning Zhou Fuqiang Xu Hua Han Pak-Ming Lau Guo-Qiang Bi 2019National Science Review2019,6,5:7
13Last Deglaciation Climatic Fluctuation Record by the Palaeo-Daocheng Ice Cap, Southeastern Qinghai-Tibetan Plateau显示文摘The last deglaciation, a key period for understanding present and future climate changes, has long been the hot topic for palaeoclimatological study. The Qinghai-Tibetan Plateau(QTP) is often a target study area for understanding hemispheric, or even global environment changes. The glacial landforms on the QTP provide a unique perspective for its climate change. In order to investigate the onset of the last deglaciation at the QTP and its regional correlation, the terrestrial cosmogenic nuclides(TCN) 10 Be and 26 Al surface exposure dating was chosen to date the roche moutonnée, the polished surface and the moraine debris located at the palaeo-Daocheng Ice Cap(pDIC), southeastern QTP. Our results show that the onset of the last deglaciation is at about 19 ka, followed by another warming event occurring around 15 ka in the p-DIC area. These timings agree well with other records, e.g. equivalent with a rapid sea level rise at 19 ka and the onset of B?lling warming event at about 15 ka. Thus, our new data can provide good reveal constraint on the climate evolution at the QTP.ZHANG Zhigang XU Xiaobin WANG Jian ZHAO Zhijun BAI Shibiao CHANG Zhi Yang 2014Acta Geologica Sinica(English Edition)2014,88,6:6
14β-Cyclodextrin functionalized graphene oxide: an efficient and recyclable adsorbent for the removal of dye pollutants显示文摘为 -cyclodextrin grafted graphene 氧化物的准备的一个新奇方法去 -- CD 被开发了。GO -- CD 被 Fourier 变换描绘红外线的光谱学, < 啜 class= “ a-plus-plus ” > 13 C NMR 光谱学,拉曼光谱学和 thermogravimetric 分析。能力去 -- 把品红酸从解决方案移开的 CD 也被学习。GO -- CD 为品红酸有一个优秀吸附能力并且能被再循环并且再使用。吸附能力去 -- 为象甲基橘子和甲又蓝色那样的另外的染料污染物质的 CD 也被调查。为三染料的吸收能力在顺序:品红酸 > 甲又蓝色 > 甲基橘子。Shanshan WANG Yang LI Xiaobin FAN Fengbao ZHANG Guoliang ZHANG 2015Frontiers of Chemical Science and Engineering2015,9,1:6
15Command and Control Cities in Global Space-economy Before and after 2008 Geo-economic Transition显示文摘The global economic downturn caused primarily by the US sub-prime mortgage crisis in 2007 engendered revenue loss of the multinational corporations.Existing studies have yet to depict the detrimental impacts on city's command and control functions induced by the sub-prime mortgage crisis together with its residual wave of global economic recession on the global spatial economy.Recent and previous studies have produced an 'instant history' of the global spatial economy before the global economic downturn undermines the global economy in late 2008.However,the waxes and wanes of major cities' command and control functions on the global economic arena before and after the outbreak of financial crisis and its associated geo-economic transitions are still poorly understood.This paper attempts to contribute a new set of customized data to update and fill in the gap in the literature with the investigation of the command and control functions of cities around the world from 2005 to 2009.Particular attentions are paid to the time-space relationship of the geo-economic transition that can capture the recent historical images of the command and control situation of different cities in the world.Ernest Ka Shing LEE Simon Xiaobin ZHAO Yang XIE 2012Chinese Geographical Science2012,22,3:5
16Temperature effect on the structural strains of an ancient Tibetan building based on long-term monitoring data显示文摘Many studies have indicated that structural strain will be significantly influenced by temperature variations,and a good understanding of the effect of temperature on structural strain is essential.A structural health monitoring system has been installed in a typical Tibetan timber building to measure the structural strains and ambient temperature since 2012.This paper presents the correlation between temperature and strain data from the monitored structure.A method combining singular spectrum analysis and polynomial regression is proposed for modeling the temperature induced strains in the structure.Singular spectrum analysis is applied to smooth the temperature data,and the correlation between the resulting temperature time series and the measured strains is obtained by polynomial regression.Parameters of the singular spectrum analysis and the regression model are selected to have the least regression error.Results show that the proposed method has both good reproduction and prediction capabilities for temperature induced strains,and that the method is accurate and effective for eliminating the effect of temperature from the measured strain.A standardized Novelty Index based on the residual strain is also used for the condition assessment of the structure.Bai Xiaobin Yang Na Yang Qingshan 2018Earthquake Engineering and Engineering Vibration2018,17,3:5
17Reconstructing Spatial Distribution of Historical Cropland in China′s Traditional Cultivated Region: Methods and Case Study显示文摘As an important part of land use/cover change(LUCC), historical LUCC in long time series attracts much more attention from scholars. Currently, based on the view of combining the overall control of cropland area and ′top-down′ decision-making behaviors, here are two global historical land-use datasets, generally referred as the Sustainability and the Global Environment datasets(SAGE datasets) and History Database of the Global Environment datasets(HYDE datasets). However, at the regional level, these global datasets have coarse resolutions and inevitable errors. Considering various factors that influenced cropland distribution, including cropland connectivity and the limitation of natural and human factors, this study developed a reconstruction model of historical cropland based on constrained Cellular Automaton(CA) of ′bottom-up′. Then, an available labor force index is used as a proxy for the amount of cropland to inspect and calibrate these spatial patterns. Applied the reconstruction model to Shandong Province, we reconstructed its spatial distribution of cropland during 8 periods. The reconstructed results show that: 1) it is properly suitable for constrained CA to simulate and reconstruct the spatial distribution of cropland in traditional cultivated region of China; 2) compared with ′SAGE datasets′ and ′HYDE datasets′, this study have formed higher-resolution Boolean spatial distribution datasets of historical cropland with a more definitive concept of spatial pattern in terms of fractional format.YANG Xuhong GUO Beibei JIN Xiaobin LONG Ying ZHOU Yinkang 2015Chinese Geographical Science2015,25,5:4
18Flow Boiling of Ammonia in a Diamond-Made MicroChannel Heat Sink for High Heat Flux Hotspots显示文摘To solve the heat dissipation problem of electronic devices with high heat flux hotspots,a diamond microchannel heat sink consisting of 37 parallel triangular microchannels with channel lengths of 45 mm and hydraulic diameters of 280|im was designed.The flow boiling heat transfer characteristics of ammonia in the microchannels were investigated under high heat fluxes of 473.9-1000.4 W/cm^2.Saturated flow boiling experiments with saturation temperatures of 25℃,30℃,and 35℃ and mass fluxes of 98-1200 kg/m^2s were conducted,as well as subcooled flow boiling with inlet subcooling of 5℃ as a comparison.The temperature and pressure drop measurements were analyzed.The main conclusions below can be drawn.(1)At a given heat flux,the heat source temperature first decreased and then increased with the mass flux,and there existed an optimum mass flux to optimize the cooling performance of the heat sink.(2)The heat transfer performance under the saturated inlet condition was obviously better than that under the subcooled inlet condition.(3)A larger saturation temperature leaded to weakening of both the heat transfer capacity and the stability of the microchannel heat sink.Notably,with the high heat diffusion ability of the diamond substrate and the great heat transfer capacity of ammonia flow boiling in microchannels,the heat sink can achieve a heat removal capacity of up to 1000.4 W/cm^2.YANG Qi MIAO Jianyin ZHAO Jingquan HUANG Yanpei FU Weichun SHEN Xiaobin 2020Journal of Thermal Science2020,29,5:4
19Farmland dataset reconstruction and farmland change analysis in China during 1661-1985显示文摘This research reconstructs China's provincial farmland dataset in the last 300 years(1661–1985) by applying factor correction, citing replacement, linear interpolation, cohesion and contrast, man-land relationship test, farming trend test, provincial administrative area adjustment, etc. on available farmland data based on China's current provincial administrative boundary. Based on this dataset, a quantitative analysis has been applied to study the farmland amount and its change characteristics at both national and provincial level. Three conclusions are derived:(1) Along with the rapid population growth, national farmland amount has increased by about 320% in the last 300 years from 424,480 km2 in the early Qing Dynasty to 1,368,600 km2 in 1985. Comparing with global and national farmland datasets, in terms of the overall trend of national farmland growth, very low deviation exists but significant variances do appear for some provinces.(2) At the beginning of the Qing Dynasty, China's farming activities mainly existed in the Yangtze River Plain, the North China Plain, the Guanzhong Basin and the Yinchuan Plain. Thereafter, reclamation activities expanded to outer agricultural areas. Regarding of the growth rate, national farmland increase can be divided into five phases. National policy, disasters, wars, and economic development, are the main factors affecting farmland changes.(3) Significant regional variances exist in farmland changes. In the space shaped by the average farmland amount and the average annual change rate of farmland, the nation can be divided into six areas.JIN Xiaobin CAO Xue DU Xindong YANG Xuhong BAI Qing ZHOU Yinkang 2015Journal of Geographical Sciences2015,25,9:4
20Single small molecule-assembled nanoparticles mediate efficient oral drug delivery显示文摘Oral drug delivery,which requires surviving the harsh environment in the gastrointestinal(Gl)tract and penetrating the intestinal epithelium,has not bee n achieved using simple formulatio n nan oparticles(NPs).Medici nal natural products(MNPs)have bee n widely used in traditi onal medicine for disease management through oral consumption.However,most pharmacologically active compounds within MNPs do not have the properties suitable for oral applicatio ns.We hypothesize that some MNPs contain n atural nano materials that can convert those compounds into oral formulations by forming NPs.After screening 66 MNPs,we identified five classes of small molecules that form NPs,many of which are capable of efficient drug encapsulation and Gl penetration.We show that one of them,dehydrotrametenolic acid(DTA),is capable of mediating oral delivery for effective disease treatment.We determined that DTA NPs assemble through hydrogen bonding and penetra怕the Gl tract via apical sodium-depe ndent bile acid tran sporter.Our study reveals a no vel class of single comp orient,small molecule-assembled NPs for oral drug delivery,and suggests a n ovel approach to modernizi ng MNPs through nano material discovery.Xin Yang Chao Ma Zeming Chen Jun Liu Fuyao Liu Rongbin Xie Haitian Zhao Gang Deng Ann TChen Ningbo Gong Lei Yao Pengjian Zuo Kangkang Zhi Jiacheng Wang Xiaobin Gao Jing Wang Louzhen Fan Jiangbing Zhou 2019Nano Research2019,12,10:4
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