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| 1 | Numerical analysis of the failure process of soil-rock mixtures through computed tomography and PFC3D models显示文摘 | Yang Ju Huafei Sun Mingxu Xing Xiaofei Wang Jiangtao Zheng | 2018 | International Journal of Coal Science & Technology2018，5，2： | 17 |
| 2 | Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells显示文摘Sjögren’s syndrome(SS)is a systemic autoimmune disease characterized by progressive inflammation and tissue damage in salivary glands and lacrimal glands.Our previous studies showed that myeloid-derived suppressor cells(MDSCs)exhibited impaired immunosuppressive function during disease progression in patients with SS and mice with experimental Sjögren’s syndrome(ESS),but it remains unclear whether restoring the function of MDSCs can effectively ameliorate the development of ESS.In this study,we found that murine olfactory ecto-mesenchymal stem cell-derived exosomes(OE-MSC-Exos)significantly enhanced the suppressive function of MDSCs by upregulating arginase expression and increasing ROS and NO levels.Moreover,treatment with OE-MSC-Exos via intravenous injection markedly attenuated disease progression and restored MDSC function in ESS mice.Mechanistically,OE-MSC-Exo-secreted IL-6 activated the Jak2/Stat3 pathway in MDSCs.In addition,the abundant S100A4 in OE-MSC-Exos acted as a key factor in mediating the endogenous production of IL-6 by MDSCs via TLR4 signaling,indicating an autocrine pathway of MDSC functional modulation by IL-6.Taken together,our results demonstrated that OE-MSC-Exos possess therapeutic potential to attenuate ESS progression by enhancing the immunosuppressive function of MDSCs,possibly constituting a new strategy for the treatment of Sjögren’s syndrome and other autoimmune diseases. | Ke Rui Yue Hong Qiugang Zhu Xiaofei Shi Fan Xiao Hailong Fu Qing Yin Yida Xing Xinfeng Wu Xiaodan Kong Huaxi Xu Jie Tian Shengjun Wang Liwei Lu | 2021 | Cellular & Molecular Immunology2021，18，2： | 12 |
| 3 | Fluorescence regional integration and differential fluorescence spectroscopy for analysis of structural characteristics and proton binding properties of fulvic acid sub-fractions显示文摘Structural characteristics and proton binding properties of sub-fractions(FA3–FA13) of fulvic acid(FA), eluted stepwise by pyrophosphate buffer were examined by use of fluorescence titration combined with fluorescence regional integration(FRI) and differential fluorescence spectroscopy(DFS). Humic-like(H-L) and fulvic-like(F-L) materials, which accounted for more than 80% of fluorescence response, were dominant in five sub-fractions of FA. Based on FRI analysis, except the response of F-L materials in FA9 and FA13, maximum changes in percent fluorescence response were less than 10% as pH was increased from 2.5 to 11.5.Contents of carboxylic and phenolic groups were compared for fluorescence peaks of FA sub-fractions based on pH-dependent fluorescence derived from DFS. Static quenching was the dominant mechanism for binding of protons by FA sub-fractions. Dissociation constants(p Ka) were calculated by use of results of DFS and the modified Stern-Volmer relationship. The p Kaof H-L, F-L, tryptophan-like and tyrosine-like materials of FA subfractions exhibited ranges of 3.17–4.06, 3.12–3.97, 4.14–4.45 and 4.25–4.76, respectively, for acidic pHs. At basic pHs, values of p Ka for corresponding materials were in ranges of 9.71–10.24, 9.62–10.99, 9.67–10.31 and 9.33–10.28, respectively. At acidic pH, protein-like(P-L)materials had greater affinities for protons than did either H-L or F-L materials. The dicarboxylic and phenolic groups were likely predominant sites of protonation for both H-L and F-L materials at both acidic and basic pHs. Amino acid groups were significant factors during proton binding to protein-like materials of FA sub-fractions at basic pH. | Fanhao Song Fengchang Wu Weiying Feng Zhi Tang John P.Giesy Fei Guo Di Shi Xiaofei Liu Ning Qin Baoshan Xing Yingchen Bai | 2018 | Journal of Environmental Sciences2018，30，12： | 9 |
| 4 | Highly conductive dodecaborate/MXene composites for high performance supercapacitors显示文摘With the increasingly prominent energy and environmental issues,the supercapacitors,as a highly efficient and clean energy conversion and storage devices,meet the requirements well.However,it is still a challenge to enhance the capacitance and energy density of supercapacitors.A novel and highly conductive dodecaborate/MXene composites have been designed for high performance supercapacitors.The surface charge property of MXene was modified by a simple ultrasonic treatment with ammonium ion,and the dodecaborate ion can be inserted into the inner surface of MXene by electrostatic adsorption.Due to the unique icosahedral cage conjugate structure formed by the B-B bond and the highly delocalized three-dimensionalπbond structure of the electrons,the negative charge is delocalied on the whole dodecaborate ion,which reduces the ability to bind to cations.Therefore,the cations can move easily,and the dodecaborate can act as a“lubricant”for ion diffusion between the MXene layers,which significantly improves the ion transfer rate of supercapacitors.The dodecaborate/MXene composites can achieve an extremely high specific capacitance of 366 F.g^-1 at a scan rate of 2 mV.s^-1,which is more than eight times higher than that of MXene(43 F1-)at the same scan rate.Our finding provides a novel route on the fabrication of the high performance supercapacitors. | Zhenxing Li Chang Ma Yangyang Wen Zhiting Wei Xiaofei Xing Junmei Chu Chengcheng Yu Kaili Wang Zhao-Kui Wang | 2020 | Nano Research2020，13，1： | 7 |
| 5 | Genotypic variation in spatiotemporal distribution of canopy light interception in relation to yield formation in cotton显示文摘Background: Within-canopy interception of photosynthetically active radiation(PAR) impacts yield and other agronomic traits in cotton(Gossypium hirsutum L.). Field experiments were conducted to investigate the influence of 6 cotton varieties(they belong to 3 different plant types) on yield, yield distribution, light interception(LI), LI distribution and the relationship between yield formation and LI in Anyang, Henan, in 2014 and 2015.Result: The results showed that cotton cultivars with long branches(loose-type) intercepted more LI than did cultivars with short branches(compact-type), due to increased LI in the middle and upper canopy. Although loose-type varieties had greater LI, they did not yield significantly higher than compact-type varieties, due to decreased harvest index. Therefore, improving the harvest index by adjusting the source-to-sink relationship may further increase cotton yield for loose-type cotton. In addition, there was a positive relationship between reproductive organ biomass accumulation and canopy-accumulated LI, indicating that enhancing LI is important for yield improvement for each cultivar. Furthermore, yield distribution within the canopy was significantly linearly related to vertical LI distribution.Conclusion: Therefore, optimizing canopy structure of different plant type and subsequently optimizing LI distribution within the cotton canopy can effectively enhance the yield. | XING Fangfang HAN Yingchun FENG Lu ZHI Xiaoyu WANG Guoping YANG Beifang FAN Zhengyi LEI Yaping DU Wenli WANG Zhanbiao XIONG Shiwu LI Xiaofei Ll Yabing | 2018 | Journal of Cotton Research2018，1，3： | 3 |
| 6 | Polytype target coverage scheme for heterogeneous wireless sensor networks using linear programming显示文摘 | Xing Xiaofei Wang Guojun Li Jie | 2014 | Wireless Communications and Mobile Computing2014，14，8： | 1 |
| 7 | MicroRNA-193b regulates proliferation, migration and invasion in human hepatocellular carcinoma cells显示文摘 | Chengwang Xu Shanshan Liu Hanjiang Fu Shuai Li Yi Tie Jie Zhu Ruiyun Xing Yinghua Jin Zhixian Sun Xiaofei Zheng | 2010 | European Journal of Cancer2010，，15： | 1 |
| 8 | Polytypetargetcoverageschemefor heterogeneous wirelesssensornetworks usinglinear programming 显示文摘 | Xing Xiaofei Wang GuojunLiJie | 2014 | WirelessCommunicationsand Mobile Computing2014，14，8： | 1 |
| 9 | Highly ordered macroporous-mesoporous Ce0.4Zr0.6O2 as dual-functional material in a polysulfide polymer显示文摘 | Zhenxing Li Jianzheng Zhang Mingming Li Xiaofei xing Qiuyu Zhang | 2018 | Nano Research2018，11，1： | 1 |
| 10 | High-density/efficient surface active sites on modified separators to boost Li-S batteries via atomic Co^(3+)-Se termination显示文摘Various and critical electrocatalytic processes are involved during the redox reactions in the Li-S batteries,which extremely depend on the surface structure and chemical state.Recently,single-atom concept unlocks a route to maximize the use of surface-active atoms,however,further increasing the density of active site is still strictly limited by the inherent structure that single-atoms are only highly-dispersed on substrate.Herein,we provide a viewpoint that an elaborate facet design with singlecrystalline structure engineering can harvest high-density surface active sites,which can significantly boost the electrocatalyst performance for excellent Li-S batteries.Specifically,the single-crystal CoSe_(2)(scCS)exhibits three-types of terminated(011)facet,efficiently obtaining the surface with a high-rich Co^(3+)–Se bond termination,in contrast with lots of surface grain boundaries and dangling bonds in polycrystalline CoSe_(2).Surprisingly,the surface active sites concentration can reach more than 69%.As anticipated,it can provide high-density and high-efficient active sites,enormously suppressing the shuttle effect and improving the reaction kinetics via accelerating the conversion and deposition of polysulfides and Li2S.This surface lattice strategy with element terminated mode is a promising approach for designing electrocatalyst effect-based energy system,not merely for Li-S batteries. | Shujie Liu Xiaofei Liu Manfang Chen Dong Wang Xin Ge Wei Zhang Xiyang Wang Chunhui Wang Tingting Qin Haozhe Qin Liang Qiao Dan Zhang Xing Ou Weitao Zheng | 2022 | Nano Research2022，15，8： | 1 |
| 11 | Comparative Nutritional Analysis on Fish Meal and Meat and Bone Meal of Harmless Treatment of Dead Pig Carcass显示文摘In order to explore the resource utilization of the harmless treatment product(pork meat and bone meal,abbreviated PM)of pigs died of non-communicable diseases,the general nutritional components and amino acid composition of PM and fish meal were determined and compared.The results showed that the contents of moisture,crude protein,crude fat and ash in PM and fish meal were 3.25%and 8.92%,66.65%and 66.67%,13.52%and 8.23%,18.25%and 21.50%,respectively.The contents of essential amino acids(EAA)in PM and fish meal were 19.94%and 22.35%,respectively.For PM and fish meal,the first limiting amino acid was Met(methionine)+Cys(cysteine),and the second limiting amino acid was Lys(lysine);their essential amino acid indexes(EAAI)were 66.60 and 77.04,respectively;and their delicious amino acid(DAA)contents were 26.89%and 23.15%,respectively.In summary,the meat and bone meal of pigs died of non-communicable diseases has the characteristics of high protein and low ash contents,and has certain development and utilization potential as a recycled waste resource,especially in aquatic feed to replace fish meal. | Xiaofei CHENG Jin XIANG Shiming DENG Xing TIAN Xiping YUAN Shaoming LI Rui SONG Li LIU | 2020 | Agricultural Biotechnology2020，9，6： | 1 |
| 12 | A novel method for ionizing radiation-induced RNA damage detection by poly(A)-tailing RT-PCR显示文摘Ionizing radiation (IR) causes severe cellular damage both directly and indirectly and disrupts RNA integrity. RNA strand breaks are the most frequent type of damage caused by IR. RNA damage is involved in the development of degenerative diseases, including Alzheimer’s disease and Parkinson’s disease. However, the mechanism of mRNA damage and any resulting pathophysiological outcomes are poorly understood. This is partly because there is a lack of sensitive tools to monitor damage randomly occurring in RNA, especially RNA strand break damage in a given RNA. In this work, a method using the reverse transcription polymerase chain reaction (RT-PCR) after poly(A) addition to 3′-end of RNA to determine RNA strand break damage in a specific RNA by poly(A) polymerase has been developed. The levels of damage in specific mRNAs, including ABL1, TP53, GADD45A and ATR from IR-treated HeLa cells were examined. Strand breaks were detected in all mRNAs examined. The study provides a novel and sensitive method based on 3 -end poly(A)-tailing RT-PCR to monitor RNA strand break damage. | TIE Yi HU Zheng LU GuiXiang FU HanJiang XING RuiYun ZHU Jie SUN ZhiXian HENG XiaoFei | 2011 | Chinese Science Bulletin2011，56，30： | 1 |
| 13 | Correlation of microRNAs responding to high dose γ-irradiation with predicted target mRNAs in HeLa cells using microarray analyses显示文摘An increasing data indicates that altered microRNAs(miRNAs)participate in the radiation-induced DNA damage response.However,a correlation of mRNA and miRNA profiles across the entire genome and in response to irradiation has not been thoroughly assessed.We analyzed miRNA microarray data collected from HeLa cells after ionizing radiation(IR),quantified the expression profiles of mRNAs and performed comparative analysis of the data sets using target prediction algorithms,Gene Ontology(GO)analysis,pathway analysis,and gene network construction.The results showed that the altered miRNAs were involved in regulation of various cellular functions.miRNA-gene network analyses revealed that miR-186,miR-106b,miR-15a/b,CCND1and CDK6 played vital role in the cellular radiation response.Using qRT-PCR,we confirmed that twenty-two miRNAs showed differential expression in HeLa cells treated with IR and some of these miRNAs affected cell cycle progression.This study demonstrated that miRNAs influence gene expression in the entire genome during the cellular radiation response and suggested vital pathways for further research. | HU Zheng TIE Yi Lü GuiXiang FU HanJiang XING RuiYun ZHU Jie SUN ZhiXian ZHENG XiaoFei | 2013 | Chinese Science Bulletin2013，58，36： | 1 |
| 14 | Collaborative target tracking in wireless sensor networks 显示文摘 | XING Xiaofei WANG Guojun LI Jie | 2014 | Ad- hoc and Sensor Networks2014，23，8： | 1 |
| 15 | Reticulon 3 attenuates the clearance of cytosolie prion aggregates via inhibiting au- tophagy显示文摘 | Chert Rui Jin Rui Wu Lu Ye Xiaofei Yang Yi Luo Kan Wang Wenxi Wu Di Ye Xing Huang Liqin Huang Tao Xiao Gengfu | 2011 | Autophagy2011，7，2： | 1 |
| 16 | The first two leading modes of the tropical Pacific and their linkage without global warming显示文摘A discrepancy remains in the first two leading empirical orthogonal function(EOF) modes of the tropical Pacific sea surface temperature anomaly(SSTA) based on observations since the 1980s. The EOF1 mode, representing the El Ni?o-Southern Oscillation(ENSO), is a robust result. However, the EOF2 features either El Ni?o Modoki(EM) or ENSO evolution during different periods, which is probably associated with the impacts of global warming. The underlying question is what the EOF2 mode of the tropical Pacific would be without global warming. Using the CMIP5 preindustrial scenario to exclude the influence of global warming, we find that the EOF1 mode of the tropical Pacific SSTA represents ENSO and that the EOF2 mode is not EM. According to the lead–lag correlation between the ENSO and EOF2 modes, the linkage between these two modes is as follows: …El Ni?o → EOF2 → La Ni?a →–EOF2 → El Ni?o…. By analyzing the evolution of sea surface temperature, surface wind, and subsurface ocean temperature anomalies, we find the mechanism linking the ENSO and EOF2 modes is the air–sea interaction associated with the ENSO cycle. This result suggests that the EOF2 mode represents an aspect of ENSO evolution under preindustrial conditions. Therefore, this study further indicates that the EM is probably due to the influence of global warming. | Yang Li QuanLiang Chen XiaoRan Liu Nan Xing ZhiGang Cheng HongKe Cai Xin Zhou Dong Chen XiaoFei Wu MingGang Li | 2019 | Earth and Planetary Physics2019，3，2： | 1 |
| 17 | Reservoir space and enrichment model of shale oil in the first member of Cretaceous Qingshankou Formation in the Changling Sag, southern Songliao Basin, NE China显示文摘The lithology, lithofacies, reservoir properties and shale oil enrichment model of the fine-grained sedimentary system in a lake basin with terrigenous clastics of large depression are studied taking the organic-rich shale in the first member of Cretaceous Qingshankou Formation(shortened as Qing 1 Member) in the Changling Sag, southern Songliao Basin as an example. A comprehensive analysis of mineralogy, thin section, test, log and drilling geologic data shows that lamellar shale with high TOC content of semi-deep lake to deep lake facies has higher hydrocarbon generation potential than the massive mudstone facies with medium TOC content, and has bedding-parallel fractures acting as effective reservoir space under over pressure. The sedimentary environments changing periodically and the undercurrent transport deposits in the outer delta front give rise to laminated shale area. The laminated shale with medium TOC content has higher hydrocarbon generation potential than the laminated shale with low TOC content, and the generated oil migrates a short distance to the sandy laminae to retain and accumulate in situ. Ultra-low permeability massive mudstone facies as the top and bottom seals, good preservation conditions, high pressure coefficient, and lamellar shale facies with high TOC are the conditions for 'lamellation type' shale oil enrichment in some sequences and zones. The sequence and zone with laminated shale of medium TOC content in oil window and with micro-migration of expelled hydrocarbon are the condition for the enrichment of 'lamination type' shale oil. The tight oil and 'lamination type' shale oil are in contiguous distribution. | LIU Bo SUN Jiahui ZHANG Yongqing HE Junling FU Xiaofei YANG Liang XING Jilin ZHAO Xiaoqing | 2021 | Petroleum Exploration and Development2021，48，3： | 1 |
| 18 | Polytype tar- get coverage scheme for heterogeneous wireless sensor networks using linear programming 显示文摘 | XING Xiaofei WANG Guojun LI Jie | 2014 | Wireless Communications and Mobile Computing2014，14，8： | 1 |
| 19 | Polytype Target Coverage Scheme for Heterogeneous Wireless Sensor Networks Using Linear Programming显示文摘 | Xing Xiaofei Wang Guojun Li Jie | 2014 | Wireless Communications and Mobile Computing2014，14，8： | 1 |
| 20 | Nonprinted IC Textiles for Wearable Electronics显示文摘1.INTRODUCTION There is an increasing interest in wearable electronic devices that can potentially change the way people live,especially in the era of comprehensive healthcare and telemedicine.Printed circuit boards(PCBs)are the basis of existing electronic device technologies,playing the role of connecting and supporting different electronic components on a plastic board to form an integrated circuit(IC)as the core of a device.However,the plastic board of traditional PCBs is too rigid to seamlessly accommodate the naturally curved surfaces of the human body. | Xiaofei Wei Wei Zhang Xing Fan | 2022 | Accounts of Materials Research2022，3，12： | 1 |
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