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| 1 | Trend analysis of cancer incidence and mortality in China显示文摘The National Central Cancer Registry of China(NCCRC)updated their nationwide statistics of cancer incidence and mortality in China according to 2013 population-based cancer registration data(due to the time required for data collection,quality control and analysis,the latest cancer statistics available in China have a 3-year lag behind the current year).In this report,the NCCRC provides a comprehensive review of cancer incidence and mortality rates,as well as the statistics overall and by geographical area,cancer sites or age groups(Chen et al.,2017a).It shows that the burden of cancer | Fang Wei Yingfen Wu Le Tang Fang Xiong Can Guo Xiayu Li Ming Zhou Bo Xiang Xiaoling Li Guiyuan Li Wei Xiong Zhaoyang Zeng | 2017 | Science China(Life Sciences)2017，60，11： | 16 |
| 2 | Xa7, a new executor R gene that confers durable and broad-spectrum resistance to bacterial blight disease in rice显示文摘Bacterial blight(BB)is a globally devastating rice disease caused by Xanthomonas oryzae pv.oryzae(Xoo).The use of disease resistance(R)genes in rice breeding is an effective and economical strategy for the control of this disease.Nevertheless,a majority of R genes lack durable resistance for long-term use under global warming conditions.Here,we report the isolation of a novel executor R gene,Xa7,that confers extremely durable,broad-spectrum,and heat-tolerant resistance to Xoo.The expression of Xa7 was induced by incompatible Xoo strains that secreted the transcription activator-like effector(TALE)AvrXa7 or PthXo3,which recognized effector binding elements(EBEs)in the Xa7 promoter.Furthermore,Xa7 induction was faster and stronger under high temperatures.Overexpression of Xa7 or co-transformation of Xa7 with avrXa7 triggered a hypersensitive response in plants.Constitutive expression of Xa7 activated a defense response in the absence of Xoo but inhibited the growth of transgenic rice plants.In addition,analysis of over 3000 rice varieties showed that the Xa7 locuswas found primarily in the indica and aus subgroups.A variation consisting of an 11-bp insertion and a base substitution(G to T)was found in EBEAvrXa7 in the tested varieties,resulting in a loss of Xa7 BB resistance.Through a decade of effort,we have identified an important BB resistance gene and characterized its distinctive interaction with Xoo strains;these findings will greatly facilitate research on the molecular mechanism of Xa7-mediated resistance and promote the use of this valuable gene in breeding. | Xifeng Chen Pengcheng Liu Le Mei Xiaoling He Long Chen Hui Liu Shurong Shen Zhandong Ji Xixi Zheng Yuchen Zhang Zhenyu Gao Dali Zeng Qian Qian Bojun Ma | 2021 | Plant Communications2021，2，3： | 9 |
| 3 | An investigation on application potentiality of microstructure heat sinks with different flow topological morphology显示文摘Microstructure heat sinks have great potential for high heat flux cooling.In this paper,we compared microchannel(MC),micro-pin-fin(MPF),manifold microchannel(MMC),and manifold micro-pin-fin(MMPF)heat sinks to figure out the pros and cons.Fluid flow and manifold unit models are used to study thermal and hydrodynamic performance.The heat sinks with different channel/fin sizes,manifold numbers,and porosities are discussed according to the pressure drop,temperature,thermal resistance,and coefficient of performance.Results show that MMC and MMPF heat sinks are superior to MC and MPF heat sinks,and there are also differences between MMC and MMPF heat sinks.Typically,the MMPF heat sink has lower maximum temperature,temperature non-uniformity,and total thermal resistance R_(tot).In contrast,the MMC heat sink has a lower pressure drop and higher COP.For the MMPF heat sink,at the nozzle width of 6.75μm and the MPF width of 70.71μm(porosity=0.167),it achieves the lowest total thermal resistance of R_(tot)=2.97×10^(-6)K m^(2)/W.Under 10^(3)W/cm^(2)heat flux,the maximum surface temperature rise is 29.74 K,and the maximum temperature difference of the heating surface is 3.15 K.This research initially provides a clear reference on the selection of single-phase cooling microstructures for ultra-high heat flux dissipation. | YAO XiaoLe SHI QianLei LIU Qian QIN Le JU Xing XU Chao | 2022 | Science China(Technological Sciences)2022，65，12： | 2 |
| 4 | The effects of training intensities on motor recovery and gait symmetry in a rat model of ischemia显示文摘 | Le Li Wei Rong Zheng Ke Xiaoling Hu Kai-yu Tong | 2013 | Brain Injury2013，，4： | 1 |
| 5 | HRCT Scans of Peripheral Non-Small Cell Lung Cancers and their Relationship with Cyclin D1 Expression:a Longitudinal Study显示文摘OBJECTIVE To investigate cyclin D1 expression in peripheral lung cancers and its relationship with CT signs and prognosis. METHODS Cyclin D1 expression in peripheral lung cancers and its relationship with the CT imaging and prognosis were analyzed retrospectively by means of SP immunohistochemistry and spiral CT scanning in 92 patients with peripheral lung cancer verified by pathology. RESULTS Cyclin D1 expression was related to deep lobulation,spiculate protuberance,short thin spinules sign and mediastina lymph node metastasis.Cyclin D1 expression was not related to tumor size,cavity,pleural indentation,histological type,differentiation,tumor TNM stage,age or sex.Cyclin D1 was a negative prognostic factor whose over-expression indicated a poor prognosis. CONCLUSION Cyclin D1 expression may play an important role in the occurrence,progress and CT scan results of lung cancers.Cyclin D1 was a negative factor whose over-expression implied a poor prognosis.Detection of the cyclin D1 and observation of the CT scan can be considered as indexes of clinical diagnosis and prognostic evaluation. | Shuhua Ma Linfa Wu Xiaomao Xu Hongbo Le Xiaoling Cheng Huihong Zhang Zhengyu Sun Zhaoxin Wang Min Wu Wei Mei Zhiguo Hu Yuguang Li | 2008 | Chinese Journal of Clinical Oncology2008，5，3： | 0 |
| 6 | Microreactor platform for continuous synthesis of electronic doped quantum dots显示文摘Electronic doped quantum dots(Ed-QDs),by heterovalent cations doping,have held promise for future device concepts in optoelectronic and spin-based technologies due to their broadband Stokes-shifted luminescence,enhanced electrical transport and tailored magnetic behavior.Considering their scale-up requirement and the low yielding of several current colloidal synthesis methods,a stable and efficient bulk synthesis strategy must be developed.Microreactors have long been recognized as an effective platform for producing nanomaterials and fabricating large-scale structures.Here,we chose microreactor platform for continuous synthesis of Ed-QDs in the air at low temperatures.By original reverse cation exchange reaction mechanism together with varying the kinetic conditions of microreactor platform,such as liquid flow rate,the Ag doped CdS(CdS:Ag)Ed-QDs with higher yield have been synthesized successfully due to the continuous synthesis advantages with a high degree of size selectivity.Enabled by microreactor engineering simulation,this research not only provides a new synthetic method towards scale-up production but also enables to improve chemical mass production of similar functional QDs for optical devices,bioimaging and innovative information processing applications. | Yuxi Li Yanbin Li Xinyuan Li Tailei Hou Chen Qiao Yunpeng Tai Xiaole Gu Di Zhao Le Sang Jiatao Zhang | 2022 | Nano Research2022，15，10： | 0 |
| 7 | An investigation on topologies of hybrid manifold,impinging-jet nozzle and micro-pin-fin heat sinks显示文摘The hybrid manifold micro-pin-fin(MMPF)heat sink combined nozzle jets is an option for large-scale integrated circuits(LSI).The demond for uniform and ultra-high heat flux removal by MMPF heat sink has not been adequately investigated.This work aims to solve the problem of fluid organization.The proposed basic tiling topologies,including square,regular hexagon,30°rhombus,and 60°rhombus topologies,provide different organized fluid flows and heat transfer patterns.The present study focuses on comparing these topologies according to independent porous medium parameters,such as nozzle pore size D_(Z),flow pore size D_(X,Y),and porosityε.The results show that the square topology achieves the smallest total thermal resistance R_(tot)value of0.0975×10^(-4)K m^2/W,while the hexagon topology achieved the highest value of COP/?T,which was 2033.9 K^(-1).According to the sensitivity analysis results,the optimal total thermal resistance can be obtained by balancing the influences of nozzle pore size,flow pore size,and porosity.The optimal pressure drop can be obtained by maximizing the porosity. | SHI QianLei YAO XiaoLe LIU Qian QIN Le JU Xing XU Chao | 2024 | Science China(Technological Sciences)2024，67，4： | 0 |
| 8 | Research on the sampling performance of a new bionic gravity sampler显示文摘Gravity sampling is of vital importance for sampling seabed sediments and understanding submarine sedimentary environments and resources.In this study,a new bionic sampler tube(BST)with non-smooth surface for low-disturbance and rapid sampling is presented.The BST with depressions and swellings on its surface was designed on the model of the non-smooth surface of the dung beetle.Sufficient theoretical calculations,numerical simulations,and experimental tests were carried out to study its sampling performance.The penetration depth,sample length,and frictional drag of the sampler tube were calculated.The finite element model and the coupled Eulerian-Lagrangian(CEL)method were used to analyze and compare its sampling performance.Laboratory and field gravity sampling tests were conducted and the results demonstrated the advantages of the BST in improving sampling performance and in reducing adhesion and drag. | Yongqiang GE Jiamin HE Jin GUO Peihao ZhANG Hao WANG Ziqiang REN Xiaoling LE Ying WANG Yuhong WANG Jiawang CHEN | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，8： | 0 |
| 9 | Study on Design Rainstorm Profile in Liuzhou City:Chicago Method显示文摘The design rainstorm profile is the basis of scientifically and rationally planning and designing urban drainage system,which can provide scientific theoretical basis and accurate design parameters for municipal construction,water and planning departments. In this paper,the minute-minute rainfall process data at Liuzhou National Meteorological Observation Station from 1975 to 2014 were used. Chicago method was used to analyze and study design rainstorm profile in urban district of Liuzhou,and the profiles of the rainfalls lasting for 30,60,90,120,150,and 180 min were obtained. The results showed that the design rainstorm profile with the same duration in each reappearance period was consistent in Liuzhou,and short-time rainfall profile roughly showed single-peak shape. The peak of each short-time design rainstorm profile was almost in 1/3 part of the whole rainfall process,and the intensity of rainfall increased with the prolonging of the recurrence period. The rainfall intensity at the peak in the same reproducing period showed ' decrease-increase-decrease' as the duration increased,and the peak value of rainfall lasting for 120 min was the maximum. | Xie Dong Su Xiaoling Liu Lei Liang Chunrong Liu Zhourong Li Yu Lan Qiu Ren Le | 2018 | Meteorological and Environmental Research2018，9，4： | 0 |
| 10 | Boosting CO_(2) electroreduction to formate via bismuth oxide clusters显示文摘Supported metal(oxide)clusters,with both rich surface sites and high atom utilization efficiency,have shown improved activity and selectivity for many catalytic reactions over nanoparticle and single atom catalysts.Yet,the role of cluster catalysts has been rarely reported in CO_(2)electroreduction reaction(CO_(2)RR),which is a promising route for converting CO_(2)to liquid fuels like formic acid with renewable electricity.Here we develop a bismuth oxide(BiOn)cluster catalyst for highly efficient CO_(2)RR to formate.The BiOn cluster catalyst exhibits excellent activity,selectivity,and stability towards formate production,with a formate Faradaic efficiency of over 90%at a current density up to 500 mA·cm^(−2)in an alkaline membrane electrode assembly electrolyzer,corresponding to a mass activity as high as 3,750 A·gBi−1.The electrolyzer with the BiOn cluster catalyst delivers a remarkable formate production rate of 0.56 mmol·min−1 at a high single-pass CO_(2)conversion of 44%.Density functional theory calculations indicate that Bi4O_(3)cluster is more favorable for stabilizing the HCOO^(*)intermediate than Bi(001)surface and single site BiC_(4)motif,rationalizing the improved formate production over the BiOn cluster catalyst.This work highlights the great importance of cluster catalysts in activity and selectivity control in electrocatalytic CO_(2)conversion. | Xiaole Jiang Le Lin Youwen Rong Rongtan Li Qike Jiang Yaoyue Yang Dunfeng Gao | 2023 | Nano Research2023，16，10： | 0 |
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