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| 1 | Effect of nanoheat stimulation mediated by magnetic nanocomposite hydrogel on the osteogenic differentiation of mesenchymal stem cells显示文摘Hyperthermia has been considered as a promising healing treatment in bone regeneration. We designed a tissue engineering hydrogel based on magnetic nanoparticles to explore the characteristics of hyperthermia for osteogenic regeneration. This nanocomposite hydrogel was successfully fabricated by incorporating magnetic Fe_3O_4 nanoparticles into chitosan/polyethylene glycol(PEG) hydrogel, which showed excellent biocompatibility and were able to easily achieve increasing temperatures under an alternative magnetic field(AMF). With uniformly dispersed nanoparticles, the composite hydrogel resulted in high viability of mesenchymal stem cells(MSCs), and the elevated temperature contributed to the highest osteogenic differentiation ability compared with direct heat treatment applied under equal temperatures. Therefore, the nanoheat stimulation method using the magnetic nanocomposite hydrogel under an AMF may be considered as an alternative candidate in bone tissue engineering regenerative applications. | Zheng Cao Dan Wang Yongsan Li Wensheng Xie Xing Wang Lei Wao Yen Wei Xiumei Wang Lingyun Zhao | 2018 | Science China(Life Sciences)2018，61，4： | 5 |
| 2 | Effects of dietary protein level on nutrients digestibility and reproductive performance of female mink(Neovison vison)during gestation显示文摘The objective of this study was to determine whether nutrient digestibility and reproductive performance of pregnant mink(Neovison vison) were affected by different dietary protein levels. One hundred and twenty female mink were randomly assigned to four groups, receiving diets of fresh material with different protein levels. The dietary protein levels,expressed as percentage of dry matter(DM),were 32,36, 40 and 44% respectively. These values corresponded to average 320, 360, 400 and 440 g protein/kg DM, respectively. Results were as follows. All of crude protein digestibility, nitrogen(N) intake, N retention increased along with dietary protein level increasing. Low protein level(32%) significantly reduced the above indicators(P < 0.05). DM digestibility and ether extract digestibility were not affected by dietary protein level. Results of mated females, barren females, kids per litter, live born kids per mated female, birth survival rate, and birth weight showed that mink achieved optimal reproductive performance when dietary protein level was 36%. In conclusion, dietary protein was anticipated to significantly influence some nutrients' utilization. Adopting the appropriate dietary protein level allow better reproduction performance. The most preferable reproductive performance was achieved when diet contained 275.5 g digestible protein per kg DM for female mink in gestation. | Qingkui Jiang Guangyu Li Tietao Zhang Haihua Zhang Xiuhua Gao Xiumei Xing Jiaping Zhao Fuhe Yang | 2015 | Animal Nutrition2015，，2： | 3 |
| 3 | The prevalence of dementia in urban and rural areas of China显示文摘 | Jianping Jia Fen Wang Cuibai Wei Aihong Zhou Xiangfei Jia Fang Li Muni Tang Lan Chu Youlong Zhou Chunkui Zhou Yong Cui Qi Wang Weishan Wang Peng Yin Nan Hu Xiumei Zuo Haiqing Song Wei Qin Liyong Wu Dan Li Longfei Jia Juexian Song Ying Han Yi Xing Peijie Y | 2013 | Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association2013，，： | 2 |
| 4 | Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis显示文摘 | LIU Jianjun XING Xiumei HUANG Haiyan | 2009 | Toxicol Appl Pharmacol2009，240，3： | 1 |
| 5 | The First High-quality Reference Genome of Sika Deer Provides Insights into High-tannin Adaptation显示文摘Sika deer are known to prefer oak leaves,which are rich in tannins and toxic to most mammals;however,the genetic mechanisms underlying their unique ability to adapt to living in the jungle are still unclear.In identifying the mechanism responsible for the tolerance of a highly toxic diet,we have made a major advancement by explaining the genome of sika deer.We generated the first high-quality,chromosome-level genome assembly of sika deer and measured the correlation between tannin intake and RNA expression in 15 tissues through 180 experiments.Comparative genome analyses showed that the UGT and CYP gene families are functionally involved in the adaptation of sika deer to high-tannin food,especially the expansion of the UGT family 2 subfamily B of UGT genes.The first chromosome-level assembly and genetic characterization of the tolerance to a highly toxic diet suggest that the sika deer genome may serve as an essential resource for understanding evolutionary events and tannin adaptation.Our study provides a paradigm of comparative expressive genomics that can be applied to the study of unique biological features in non-model animals. | Xiumei Xing Cheng Ai Tianjiao Wang Yang Li Huitao Liu Pengfei Hu Guiwu Wang Huamiao Liu Hongliang Wang Ranran Zhang Junjun Zheng Xiaobo Wang Lei Wang Yuxiao Chang Qian Qian Jinghua Yu Lixin Tang Shigang Wu Xiujuan Shao Alun Li Peng Cui Wei Zhan Sheng Zhao Zhichao Wu Xiqun Shao Yimeng Dong Min Rong Yihong Tan Xuezhe Cui Shuzhuo Chang Xingchao Song Tongao Yang Limin Sun Yan Ju Pei Zhao Huanhuan Fan Ying Liu Xinhui Wang Wanyun Yang Min Yang Tao Wei Shanshan Song Jiaping Xu Zhigang Yue Qiqi Liang Chunyi Li Jue Ruan Fuhe Yang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 1 |
| 6 | Sequencing and Analysis of G HR Gene from Genomic DNA Pools of Mink显示文摘In order to study the single nucleotide polymorphisms(SNPs) of growth hormone receptor( GHR) gene in mink populations, genomic DNA pools of Minghua black minks and silver-blue minks were constructed, and the 10 thexon of GHR gene was PCR amplified from the two DNA pools and sequenced. The results showed that two SNPs were found at position 209(T/C) and position 533(C/A) of the 10 thexon of GHR gene in the two mink populations. | Rong Min Xu Jiaping Tu Jianfeng Gao Feng Xing Xiumei | 2018 | Animal Husbandry and Feed Science2018，10，3： | 0 |
| 7 | Analysis of the valence electronic structures and calculation of the physical properties of Fe,Co,and Ni显示文摘The valence electronic structures of Fe, Co and Ni have been investigated with Empirical Electron Theory of Solids and Molecules. The magnetic moments, Curie temperature, cohesive energy and melting point have been calculated according to the valence electronic structure. These calculations fit the experimental data very well. Based on the calculations, the magnetic moments are proportional to the number of 3d magnetic electrons. Curie temperatures are related to the magnetic electrons and the bond lengths between magnetic atoms. Cohesive energies increase with the increase of the number of covalent electrons, and the decrease of the number of magnetic and dumb pair electrons. The melting point is mainly related to the number of covalent electron pairs distributed in the strongest bond. The contribution from the lattice electrons is very small, the dumb pair electrons weaken the melting point; however, the contribution to melting point of the magnetic electrons can be neglected. It reveals that the magnetic and thermal properties are closely related to the valence electronic structures, and the changes or transitions between the electrons obviously affect the physical properties. | WU WenXia XUE ZhiYong HONG Xing LI XiuMei GUO YongQuan | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，6： | 0 |
| 8 | Development Characteristics,Problems and Recommendations of Sweet Potato Industry in Fuyang City显示文摘The development of sweet potato industry in Fuyang City takes on following characteristics:increase in planting area of specialized households and professional cooperatives;increase in production input and yield;constant optimization of planting varieties;diversified planting modes.Sweet potato industry has made significant contribution to Fuyang City:(1)enriching types of agricultural products and promoting healthy diet;(2)driving development of agricultural product processing industry and increasing the employment rate of rural labor;(3)increasing financial revenue and rate of export-making foreign exchange of agricultural products;(4)increasing farmers'income and promoting new socialist countryside construction.In line with comparative advantages and existing problems of sweet potato industry in Fuyang City,it presents corresponding industrial development recommendations. | Zemin FAN Xinliang LIU Yuling ZHU Xiumei WANG Xiaolu JIANG Fengwu XING | 2013 | Asian Agricultural Research2013，5，12： | 0 |
| 9 | Analysis of the Indicence and Survival of Female Breast Cancer Patients in Beijing Over a 20-Year Period显示文摘 | Qijun Wang Weixing Zhu Xiumei Xing Chenxu Qu | 2006 | Chinese Journal of Clinical Oncology2006，3，6： | 0 |
| 10 | Analysis on Growth and Development Laws of Different Mink Varieties显示文摘This study was conducted to investigate the growth and development laws of different mink varieties. The weights of six mink varieties were determined at different growth and development stages,respectively. The growth curves were drawn,and the differences in 150-day-old weight were analyzed. The results showed that the weight of each mink variety grew rapidly after weaning to adult weight; the weight of sliver blue mink was significantly higher than those of imported regal white mink and imported palomino mink; and there were no significant differences between other varieties. | Min RONG Jianfeng TU Zhiming ZHANG Xiumei XING | 2018 | Agricultural Biotechnology2018，7，5： | 0 |
| 11 | Effects of electroacupuncture combined with hydrogel on the formation and changes in the glial scar in rats with spinal cord injury显示文摘Objective: To observe the effect of electroacupuncture(EA) combined with oriented conductive bioprotein hydrogel(OCBH) on the recovery of nerve function in rats with complete spinal cord injury(SCI)and to explore its effect and mechanism on the formation and changes of glial scars.Methods: A total of 72 female Sprague-Dawley rats were randomly divided into groups according to the treatment received. A rat model of complete SCI was constructed using a spinal cord transection.Behavioral assessments, hematoxylin-eosin(H&E) staining, immunofluorescence staining, and Western blotting were performed at a fixed period after the operation.Results: The material group and the material + EA group obtained better results in the behavioral assessments(all P <.05) and the H&E staining. In the immunofluorescence staining and Western blotting,the GFAP protein was expressed more and denser in the material group and the material + EA group than in the model group, and the density of the GFAP expression in the material + EA group was lower at week 12 than in the material group(all P <.05). The expression of complement C3 in the model, material,and material + EA groups decreased in turn. Some inflammatory factors and the NF-κB signaling pathway showed similar results in the Western blotting(all P <.05). The expression of the GDNF protein in the material + EA group was significantly higher than that in the model group and the material group(both P <.01).Conclusion: EA combined with OCBH can promote the recovery of motor functions after SCI by facilitating the formation of glial scars in the early stage, preventing the further spread of an inflammatory response that would affect the activation of A1/A2 astrocytes and change the morphology of glial scars at the spinal cord-material interface in its late stage. | Kaitan Yang Yushan Gao Yongdong Yang Chuanhong Li Zheng Cao Xiumei Wang Zaibo Li Xing Yu | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，2： | 0 |
| 12 | Boundedness of semilinear Duffing equations with singularity显示文摘我们证明方程 x + V (x)= D 的所有解决方案的固定<潜水艇class=“ a-plus-plus ”> x G ( x , t )在 V (x)具有单个潜力的地方,即, lim <潜水艇class=“ a-plus-plus ”> x1 V (x)=+,和 G ( x , t )被围住并且在 t 周期。我们在 V (x) 和 G 上给足够的条件(x, t ) 所有答案被围住保证那。 | Xiumei XING Lei JIAO | 2014 | Frontiers of Mathematics in China2014，9，6： | 0 |
| 13 | Photodegradation of new herbicide HW-02 in organic solvents显示文摘HW-02 is a new organophosphates herbicide which is discovered and developed in China. The kinetics and mechanism of HW- 02 photodegradation in the organic solvents were studied at 25°C under the irradiation of ultraviolet light. The results showed that photochemical reaction of HW-02 in organic solvents such as n-hexane, methanol, dimethyl benzene and acetone under UV light could be well described by the first kinetic equation, and the photodegradation efficiency decreased with a order of n-hexane > methanol > xylene > acetone. The photodegradation efficiency constant of HW-02 in n-hexane, methanol, xylene and acetone were 4.951 × 10 2 , 3.253 × 10 2 , 2.377 × 10 2 and 1.628 × 10 2 min 1 , and the corresponding half-lives were 13.99, 21.20, 29.15 and 42.56 min, respectively. By separation and identification of photoproducts using GC-MS, it could be concluded that HW-02 was photolyzed through ester cleavage, photo-dechlorination and photoisomerization of the molecule itself. | Zhongbin Lu Zhiguang Hou Xiumei Wang Siwei Wang Yanyan Shang Xing Yuan | 2010 | Journal of Environmental Sciences2010，22，11： | 0 |
| 14 | Developmental Changes of GHR Gene Expression in Multiple Tissues of Mink显示文摘[Objective] The paper was to explore the changes of GHR gene expression in different tissues of mink.[Method] With American mink as the research object, the expression volumes of GHR gene in heart, liver, spleen, lung, kidney, intestine and skin tissues at different growth stages(45, 90, 120, 150 and 180 days of age) were detected by real-time PCR, and comparative analysis was performed.[Result] The GHR gene expressions in heart, liver and spleen tissues at 180 days of age were extremely higher than those at other days of age( P<0.01). The GHR gene expression in lung tissue at 120 days of age was extremely higher than those at other days of age( P<0.01). The GHR gene expressions in intestine tissue at 45 and 120 days of age were extremely higher than those at other days of age(P<0.01), but no significant difference was observed between 45 and 120 days of age(P>0.05). The GHR gene expression in kidney tissue at 150 days of age was significantly higher than those at other days of age( P<0.05).The GHR gene expression in skin tissue was extremely higher than that those at other days of age( P<0.01). The GHR gene expressions in intestinal tissue at 45 and 120 days of age were extremely higher than those in other tissues(P<0.01). The GHR gene expressions in skin tissue at 90 days of age was extremely higher than those in other tissues(P<0.01). The GHR gene expressions in intestine, spleen and kidney tissues at 150 days of age were extremely higher than those in other tissues(P<0.01). The GHR gene expressions in spleen tissue at 180 days of age was extremely higher than those in other tissues(P<0.01).[Conclusion] The expression of GHR gene in mink showed obvious spatio-temporal specificity. | Rong Min Tu Jianfeng Yang Ying Xu Jiaping Xing Xiumei | 2019 | Animal Husbandry and Feed Science2019，11，2： | 0 |
| 15 | Gene characterization and phylogenetic analysis of four mitochondrial genomes in Caenogastropoda显示文摘Caenogastropoda is a highly diverse group,containing~60%of all existing gastropods.Species in this subclass predominantly inhabit marine environments and have a high ecological and economic value.Owing to the increase in relevant phylogenetic studies,our understanding of between species relatedness in Caenogastropoda has improved.However,the biodiversity,taxonomic status,and phylogenetic relationships of this group remain unclear.In the present study,we performed next-generation sequencing of four complete mitochondrial genomes from three families(Buccinidae,Columbellidae,and Cypraeidae)and the four mitogenomes were classical circular structures,with a length of 16177 bp in Volutharpa ampullacea,16244 bp in Mitrella albuginosa,16926bp in Mauritia arabica asiatica and 15422 bp in Erronea errones.Base composition analysis indicated that whole sequences were biased toward A and T.Then compared them with 171 complete mitochondrial genomes of Caenogastropoda.The phylogenetic relationship of Caenogastropoda derived from Maximum Likelihood(ML)and Bayesian Inference(BI)trees constructed based on CDS sequences was consistent with the results of traditional morphological analysis,with all three families showing close relationships.This study supported Caenogastropoda at the molecular level as a separate clade of Mollusca.According to our divergence time estimations,Caenogastropoda was formed during the middle Triassic period(~247.2–237 Ma).Our novel mitochondrial genomes provide evidence for the speciation of Caenogastropoda in addition to elucidating the mitochondrial genomic evolution of this subclass. | Jiangyong Qu Wanqi Yang Xindong Teng Li Xu Dachuan Zhang Zhikai Xing Shuang Wang Xiumei Liu Lijun Wang Xumin Wang | 2024 | Acta Oceanologica Sinica2024，43，2： | 0 |
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