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您的检索式：作者名="Xingxue Cheng"
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| 1 | Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination显示文摘 | Yiqiang Cui Yuyu Niu Jiankui Zhou Yongchang Chen Yiwei Cheng Shangang Li Zongyong Ai Chu Chu Hong Wang Bo Zheng Xuejin Chen Jiahao Sha Xuejiang Guo Xingxu Huang Weizhi Ji | 2018 | Cell Research2018，28，3： | 13 |
| 2 | Crack nucleation and propagation simulation in brittle two-phase perforated/particulate composites by a phase field model显示文摘Fracture is a very common failure mode of the composite materials,which seriously affects the reliability and service-life of composite materials.Therefore,the study of the fracture behavior of the composite materials is of great significance and necessity,which demands an accurate and efficient numerical tool in general cases because of the complexity of the arising boundary-value or initial-boundary value problems.In this paper,a phase field model is adopted and applied for the numerical simulation of the crack nucleation and propagation in brittle linear elastic two-phase perforated/particulate composites under a quasi-static tensile loading.The phase field model can well describe the initiation,propagation and coalescence of the cracks without assuming the existence and the geometry of the initial cracks in advance.Its numerical implementation is realized within the framework of the finite element method(FEM).The accuracy and the efficiency of the present phase field model are verified by the available reference results in literature.In the numerical examples,we first study and discuss the influences of the hole/particle size on the crack propagation trajectory and the force-displacement curve.Then,the effects of the hole/particle shape on the crack initiation and propagation are investigated.Furthermore,numerical examples are presented and discussed to show the influences of the hole/particle location on the crack initiation and propagation characteristics.It will be demonstrated that the present phase field model is an efficient tool for the numerical simulation of the crack initiation and propagation problems in brittle two-phase composite materials,and the corresponding results may play an important role in predicting and preventing possible hazardous crack initiation and propagation in engineering applications. | Xingxue Lu Yuliang Hou Ying Tie Cheng Li Chuanzeng Zhang | 2020 | Acta Mechanica Sinica2020，36，2： | 5 |
| 3 | Crack propagation simulation in brittle elastic materials by a phase field method显示文摘To overcome the difficulties of re-meshing and tracking the crack-tip in other computational methods for crack propagation simulations,the phase field method based on the minimum energy principle is introduced by defining a continuous phase field variable(x)∈[0,1]to characterize discontinuous cracks in brittle materials.This method can well describe the crack initiation and propagation without assuming the shape,size and orientation of the initial crack in advance.In this paper,a phase field method based on Miehe's approach[Miehe et al.,Comp.Meth.App.Mech.Eng.(2010)]is applied to simulate different crack propagation problems in twodimensional(2D),isotropic and linear elastic materials.The numerical implementation of the phase field method is realized within the framework of the finite element method(FEM).The validity,accuracy and efficiency of the present method are verified by comparing the numerical results with other reference results in literature.Several numerical examples are presented to show the effects of the loading type(tension and shear),boundary conditions,and initial crack location and orientation on the crack propagation path and force-displacement curve.Furthermore,for a single edge-cracked bi-material specimen,the influences of the loading type and the crack location on the crack propagation trajectory and force-displacement curve are also investigated and discussed.It is demonstrated that the phase field method is an efficient tool for the numerical simulation of the crack propagation problems in brittle elastic materials,and the corresponding results may have an important relevance for predicting and preventing possible crack propagations in engineering applications. | Xingxue Lu Cheng Li Ying Tie Yuliang Hou Chuanzeng Zhang | 2019 | Theoretical & Applied Mechanics Letters2019，9，6： | 2 |
| 4 | Association of self-reported health with alcohol consumption: a study conducted among Chinese and Canadian middle-aged and older adults显示文摘There has been lack of studies that examine the relationship between self-rated health(SRH)and alcohol consumption,particularly in middle-aged and older adult populations.This study aims to investigate association of SRH status with alcohol consumption in middle-aged and older adult populations.The study is a cross-sec-tional study design that was based on the China Health and Retired Longitudinal study(CHARLS)and the Canadian Alcohol and Drug Monitoring Survey(CAD-UMS)and the Canadian Alcohol,Tobacco and Drug Survey(CTADS).Measure of health is SRH status and self-reported alcohol use.Multinomial logistic regres-sion was performed to model the data and the odds ratio of self-reported excel-lent,very good,good and fair(versus poor)for current and former drinkers versus nondrinkers and current drinkers versus former drinkers was estimated in models after adjusting for covariates.This study found that in both Chinese and Canadian adult populations,current drinkers reported better health status than former drink-ers;lifetime nondrinkers reported better health status than former drinkers.Current drinkers reported better health status than nondrinkers.Canadian moderate drinkers(1.3-44 g per day)tended to report better health compared with occasional drinkers and Chinese heavy drinkers(45+grams per day)reported better health status com-pared with occasional drinkers in both populations.This study found current drink-ers tended to have better health status than former drinker and lifetime nondrinkers in adult populations.Nondrinkers tended to report better health status than former drinkers.Low and medium drinkers reported better health status. | Jinhui Zhao Hongpeng Sun Yana Ma Xingxue Cheng | 2020 | China Population and Development Studies2020，4，4： | 0 |
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