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| 1 | Enhancement of acellular cartilage matrix scaffold by Wharton’s jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration显示文摘Articular cartilage defect repair is a problem that has long plagued clinicians.Although mesenchymal stem cells(MSCs)have the potential to regenerate articular cartilage,they also have many limitations.Recent studies have found that MSC-derived exosomes(MSC-Exos)play an important role in tissue regeneration.The purpose of this study was to verify whether MSC-Exos can enhance the reparative effect of the acellular cartilage extracellular matrix(ACECM)scaffold and to explore the underlying mechanism.The results of in vitro experiments show that human umbilical cord Wharton’s jelly MSC-Exos(hWJMSC-Exos)can promote the migration and proliferation of bone marrow-derived MSCs(BMSCs)and the proliferation of chondrocytes.We also found that hWJMSC-Exos can promote the polarization of macrophages toward the M2 phenotype.The results of a rabbit knee osteochondral defect repair model confirmed that hWJMSC-Exos can enhance the effect of the ACECM scaffold and promote osteochondral regeneration.We demonstrated that hWJMSC-Exos can regulate the microenvironment of the articular cavity using a rat knee joint osteochondral defect model.This effect was mainly manifested in promoting the polarization of macrophages toward the M2 phenotype and inhibiting the inflammatory response,which may be a promoting factor for osteochondral regeneration.In addition,microRNA(miRNA)sequencing confirmed that hWJMSC-Exos contain many miRNAs that can promote the regeneration of hyaline cartilage.We further clarified the role of hWJMSC-Exos in osteochondral regeneration through target gene prediction and pathway enrichment analysis.In summary,this study confirms that hWJMSC-Exos can enhance the effect of the ACECM scaffold and promote osteochondral regeneration. | Shuangpeng Jiang Guangzhao Tian Zhen Yang Xiang Gao Fuxin Wang Juntan Li Zhuang Tian Bo Huang Fu Wei Xinyu Sang Liuqi Shao Jian Zhou Zhenyong Wang Shuyun Liu Xiang Sui Quanyi Guo Weimin Guo Xu Li | 2021 | Bioactive Materials2021，6，9： | 11 |
| 2 | An Association Study on the Cognitive Function and the Cerebral Grey Matter Volume of Patients with First-Episode Schizophrenia显示文摘 | Xinyue ZHANG Jingjing YAO Yiding LV Xiaoxin ZHAO Yuan LI Yuxiu SUI Zhiping DAI | 2018 | 上海精神医学2018，30，3： | 4 |
| 3 | Balancing the anionic framework polarity for enhanced thermoelectric performance in YbMg_(2)Sb_(2) Zintl compounds显示文摘1-2-2-type Zintl phase compound has aroused great interest for potential thermoelectric applications.However,YbMg_(2)Sb_(2) is seldom studied due to the very low electrical conductivity resulting from the large difference in the electronegativity between Mg and Sb.In this paper,we adjust the covalently bonded network of MgeSb by replacing part of the Mg with Zn which has the electronegativity closer to that of Sb.The decreased polarity in the anionic framework offers more free distance for electrons for the enhanced Hall mobility and electrical conductivity.Together with the increased point defect and the decreased lattice thermal conductivity by introduction of Zn,the maximum ZT value of ~0.8 at 773 K is achieved in YbMg_(0.9)Zn_(1.1)Sb_(2) which is~100% enhancement compared with that of YbMg_(2)Sb_(2). | Zongwei Zhang Xinyu Wang Yijie Liu Chen Chen Honghao Yao Li Yin Xiaofang Li Shan Li Fan Zhang Fengxian Bai Jiehe Sui Bo Yu Feng Cao Xingjun Liu Jun Mao Guoqiang Xie Qian Zhang | 2019 | Journal of Materiomics2019，5，4： | 3 |
| 4 | Phase Boundary Mapping in ZrNiSn Half-Heusler for Enhanced Thermoelectric Performance显示文摘The solubility range of interstitial Ni in the ZrNi1+xSn half-Heusler phase is a controversial issue,but it has an impact on the thermoelectric properties.In this study,two isothermal section phase diagrams of the Zr-Ni-Sn ternary system at 973K and 1173 K were experimentally constructed based on the binary phase diagrams of Zr-Ni,Zr-Sn,and Ni-Sn.The thermodynamic equilibrium phases were obtained after a long time of heating treatment on the raw alloys prepared by levitation melting.Solubilities of x<0:07 at 973 K and x<0:13 at 1173 K were clearly indicated.An intermediate-Heusler phase with a partly filled Ni void was observed,which is believed to be beneficial to the lowered lattice thermal conductivity.The highest ZT value~0:71 at 973 K was obtained for ZrNi_(1.11)Sn_(1.04).The phase boundary mapping provides an important instruction for the further optimization of ZrNiSn-based materials and other systems. | Xiaofang Li Pengbo Yang Yumei Wang Zongwei Zhang Dandan Qin Wenhua Xue Chen Chen Yifang Huang Xiaodong Xie Xinyu Wang Mujin Yang Cuiping Wang Feng Cao Jiehe Sui Xingjun Liu Qian Zhang | 2020 | Research2020，，1： | 2 |
| 5 | Hierarchical macro-microporous WPU-ECM scaffolds combined with Microfracture Promote in Situ Articular Cartilage Regeneration in Rabbits显示文摘Tissue engineering provides a promising avenue for treating cartilage defects.However,great challenges remain in the development of structurally and functionally optimized scaffolds for cartilage repair and regeneration.In this study,decellularized cartilage extracellular matrix(ECM)and waterborne polyurethane(WPU)were employed to construct WPU and WPU-ECM scaffolds by water-based 3D printing using low-temperature deposition manufacturing(LDM)system,which combines rapid deposition manufacturing with phase separation techniques.The scaffolds successfully achieved hierarchical macro-microporous structures.After adding ECM,WPU scaffolds were markedly optimized in terms of porosity,hydrophilia and bioactive components.Moreover,the optimized WPU-ECM scaffolds were found to be more suitable for cell distribution,adhesion,and proliferation than the WPU scaffolds.Most importantly,the WPU-ECM scaffold could facilitate the production of glycosaminoglycan(GAG)and collagen and the upregulation of cartilage-specific genes.These results indicated that the WPU-ECM scaffold with hierarchical macro-microporous structures could recreate a favorable microenvironment for cell adhesion,proliferation,differentiation,and ECM production.In vivo studies further revealed that the hierarchical macro-microporous WPU-ECM scaffold combined with the microfracture procedure successfully regenerated hyaline cartilage in a rabbit model.Six months after implantation,the repaired cartilage showed a similar histological structure and mechanical performance to that of normal cartilage.In conclusion,the hierarchical macro-microporous WPU-ECM scaffold may be a promising candidate for cartilage tissue engineering applications in the future. | Mingxue Chen YangYang Li Shuyun Liu Zhaoxuan Feng Hao Wang Dejin Yang Weimin Guo Zhiguo Yuan Shuang Gao Yu Zhang Kangkang Zha Bo Huang Fu Wei Xinyu Sang Qinyu Tian Xuan Yang Xiang sui Yixin Zhou Yufeng Zheng Quanyi Guo | 2021 | Bioactive Materials2021，6，7： | 1 |
| 6 | Sulfur vs. tellurium: the heteroatom effects on the nonfullerene acceptors显示文摘The effect of chalcogen heteroatom variation on donor materials has been systematically investigated. However, this effect on acceptors has rarely been explored. Herein, nonfullerene acceptors BFPSP and BFPTP were reported by simply changing the chalcogen atoms from S to Te. The differences between BFPSP and BFPTP in light absorption, energy levels, excited-state lifetimes, energy loss, charge mobilities, morphology, and photovoltaic properties were systematically investigated to understand the heteroatom effects. More importantly, the electroluminescence spectra, external quantum efficiency of photovoltaics and TDDFTcalculations revealed that the triplet excited state(T1) in energy of BFPTP equals to the charge transfer(CT) state in PBDBT:BFPTP, which allows T1 excitons, generated by intersystem crossing, to split into free charges to contribute to the efficiency.This contribution provides a strategy for tuning the photophysical properties of nonfullerene acceptors and designing high performance triplet materials for OSCs. | Lei Yang Linqing Qin Yunxiao Xu Huotian Zhang Lei Lv Kepeng Chen Xinyu Sui Yangguang Zhong Yuan Guo Feng Gao Jianzhang Zhao Yuhao Li Xinfeng Liu Yuanping Yi Xinhui Lu Aidong Peng Hui Huang | 2019 | Science China Chemistry2019，62，7： | 1 |
| 7 | Unsupervised machine learning for discovery of promising half-Heusler thermoelectric materials显示文摘hermoelectric materials can be potentially applied to waste heat recovery and solid-state cooling because they allow a direct energy conversion between heat and electricity and vice versa.The accelerated materials design based on machine learning has enabled the systematic discovery of promising materials.Herein we proposed a successful strategy to discover and design a series of promising half-Heusler thermoelectric materials through the iterative combination of unsupervised machine learning with the labeled known half-Heusler thermoelectric materials.Subsequently,optimized zT values of~0.5 at 925 K for p-type Sc_(0.7)Y_(0.3)NiSb_(0.97)Sn_(0.03)and~0.3 at 778 K for n-type Sc_(0.65)Y_(0.3)Ti_(0.05)NiSb were experimentally achieved on the same parent ScNiSb. | Xue Jia Yanshuai Deng Xin Bao Honghao Yao Shan Li Zhou Li Chen Chen Xinyu Wang Jun Mao Feng Cao Jiehe Sui Junwei Wu Cuiping Wang Qian Zhang Xingjun Liu | 2022 | npj Computational Materials2022，，1： | 1 |
| 8 | Phase/size dual controlled 2D semiconductor In_(2)X_(3)(X=S,Se,Te)for saturable absorption modulation显示文摘The production of two-dimensional nanosheets(2D NSs)with all sizes(1-100 nm)and few(<10)layers is highly desired but far from satisfactory.Herein,we report an all-physical top-down method to produce indium chalcogenide(In2X3(X=S,Se,Te))NSs with wide-range(150-3.0 nm)controlled sizes.The method combines silica-assisted ball-milling and sonication-assisted solvent exfoliation to fabricate multiscale NSs with varying distributions,which are then precisely separated by cascade centrifugation.Multiple characterization techniques reveal that the as-produced In2X3 NSs are intrinsic and defect-free and remainβ-phase during the whole process.The redispersions of In2X3 NSs exhibit prominent excitation wavelength-,solvent-,concentration-,and size-dependent photoluminescence.The NSs-poly(methyl methacrylate)(PMMA)hybrid thin films demonstrate strong size effects in nonlinear saturation absorption.The absolute modulation depths of 35.4%,43.3%,47.2%and saturation intensities of 1.63,1.05,0.83 MW·cm^(−2)(i.e.,163,105,and 83 nJ·cm^(−2))are derived for the In_(2)S_(3),In_(2)Se_(3),and In2Te3 quantum sheets,respectively.Our method paves the way for mass production and full exploration of full-scale 2D NSs. | Weibiao Wang Zhexue Chen Xinyu Sui Yueqi Li Xinfeng Liu Yong Zhang | 2022 | Nano Research2022，15，6： | 1 |
| 9 | Lateral quantum confinement regulates charge carrier transfer and biexciton interaction in CdSe/CdSeS core/crown nanoplatelets显示文摘Charge carrier dynamics essentially determines the performance of various optoelectronic applications of colloidal semiconductor nanocrystals.Among them,two-dimensional nanoplatelets provide new adjustment freedom for their unique core/crown heterostructures.Herein,we demonstrate that by fine-tuning the core size and the lateral quantum confinement,the charge carrier transfer rate from the crown to the core can be varied by one order of magnitude in CdSe/CdSeS core/alloy-crown nanoplatelets.In addition,the transfer can be affected by a carrier blocking mechanism,i.e.,the filled carriers hinder further possible transfer.Furthermore,we found that the biexciton interaction is oppositely affected by quantum confinement and electron delocalization,resulting in a non-monotonic variation of the biexciton binding energy with the emission wavelength.This work provides new observations and insights into the charge carrier transfer dynamics and exciton interactions in colloidal nanoplatelets and will promote their further applications in lasing,display,sensing,etc. | Yige Yao Xiaotian Bao Yunke Zhu Xinyu Sui An Hu Peng Bai Shufeng Wang Hong Yang Xinfeng Liu Yunan Gao | 2023 | Nano Research2023，16，7： | 0 |
| 10 | CH_(3)I sensing using yttrium single atom-doped perovskite nanocrystals显示文摘Nanocrystals(NCs)of cesium lead halide perovskites are optically unstable,which prevents their use in optical sensors.The combination of perovskite NCs and metal single atoms(SAs)may be a good solution to this issue.Unfortunately,depositing metal SAs on perovskite NCs remains a challenge due to relative weak metal-halide bonds.Herein,we present that,via a photo assisted method using cesium lead halide perovskite NCs as host material to anchor Y single atoms,we successfully synthesize Y SA anchored CsPbBr_(3)NCs(Y-SA/CsPbBr_(3)NCs)with outstanding fluorescence stability through the formation of two Y-O bonds and two Y-Br bonds.In comparison to bare CsPbBr_(3)NCs,Y-SA/CsPbBr_(3)NCs possess more stable optical characteristics.The as-synthesized Y-SA/CsPbBr_(3)NCs can be employed as a colorimetric platform to perform rapid CH_(3)I sensing.Detection limit of 0.044 ppm is exhibited in this approach with excellent anti-interference performance.The YSA/CsPbBr_(3)NCs-based system has been applied to the detection of CH_(3)I in sweet potato samples with satisfying results. | Xiaowei Feng Yuanlong Qin Rui Sui Guo Wang Xinyu Zhang Xinyu Liu Jiajing Pei Di Liu Zhengbo Chen | 2023 | Nano Research2023，16，7： | 0 |
| 11 | Phase-modulated quantum-sized TMDs for extreme saturable absorption显示文摘Two-dimensional semiconductors such as transition metal dichalcogenides(TMDs)have attracted much interest in the past decade.Herein,we present an all-physical top-down method for the scalable production of the intrinsic TMD quantum sheets(QSs).The phases of the TMDs(e.g.,2H-MoSe_(2),2H-WSe_(2),and Td-WTe2)remain stable during the transformation from bulk to QSs.However,phase transition(from Td to 2H)is detected in MoTe2.Such phase-modulation by size-reduction has never been reported before.The TMD QSs can be well dispersed in solvents,resulting in remarkable photoluminescence with excitation wavelength-,concentration-,and solvent-dependence.Meanwhile,the TMD QSs can be readily solution-processed into hybrid thin films,which demonstrate exceptional nonlinear saturation absorption(NSA).Notably,2H-MoTe2 QSs in poly(methyl methacrylate)show extremely high NSA performance with(absolute)modulation depth up to 46.6%and saturation intensity down to 0.81 MW·cm^(−2).Our work paves the way towards quantum-sized TMDs. | Zhexue Chen Xinyu Sui Zhangqiang Li Yueqi Li Xinfeng Liu Yong Zhang | 2023 | Nano Research2023，16，4： | 0 |
| 12 | Silver based single atom catalyst with heteroatom coordination environment as high performance oxygen reduction reaction catalyst显示文摘Ag is a potential low-cost oxygen reduction reaction(ORR)catalyst in alkaline condition,which is important for the zinc-air batteries.Here,we report that an Ag based single atom catalyst with heteroatom coordination.Ag1-h-NPClSC,has been synthesized and shown much improved performance towards ORR by manipulating the coordination environment of the Ag center.It shows a high half wave potential(0.896 V)and a high turnover frequency(TOF)(5.9 s^(−1))at 0.85 V,which are higher than the previously reported Ag based catalysts and commercial Pt/C.A zinc-air battery with high peak power density of 270 mW·cm^(−2)is fabricated by using the Ag1-h-NPClSC as air electrode.The high performance is attributed to(1)the hollow structure providing good mass transfer;(2)the single atom metal center structure providing high utility of the Ag;(3)heteroatom coordination environment providing the adjusted binding to the ORR intermediates.Density functional theory(DFT)calculations show that the energy barrier for the formation of OOH*,which is considered as the rate determine step for ORR on Ag nanoparticles,is lowered on Ag1-h-NPClSC,thus improving the ORR activity.This work demonstrates that the well manipulated Ag based single atom catalysts are promising in electrocatalysis. | Rui Sui Xuejiang Zhang Xingdong Wang Xinyu Wang Jiajing Pei Yufeng Zhang Xuerui Liu Wenxing Chen Wei Zhu Zhongbin Zhuang | 2022 | Nano Research2022，15，9： | 0 |
| 13 | De novo creation of popcorn-like fragrant foxtail millet显示文摘Aroma plays a crucial role in the sensory appeal and enjoyment of food,and it significantly impacts the grain quality of cereals,thereby influencing the value and consumption of agricultural products.For example,aromatic rice varieties like Basmati and Jasmine are renowned for their distinct aroma and command almost double the price of regular rice in the market. | Yanyan Zhang Qiang He Shihui Zhang Xinyu Man Yi Sui Guanqing Jia Sha Tang Hui Zhi Chuanyin Wu Xianmin Diao | 2023 | Journal of Integrative Plant Biology2023，65，11： | 0 |
| 14 | Investigation of charge transfer between donor and acceptor for small-molecule organic solar cells by scanning tunneling microscopy and ultrafast transient absorption spectroscopy显示文摘Small-molecule organic solar cell is a category of clean energy potential device since charge transfers between donor and acceptor.The morphologies,co-assembly behavior,interaction sites,and charge transfer of BTID-nF(n=1,2)/PC71BM donor-acceptor system in the active layer of organic solar cell have been studied employing scanning tunneling microscopy(STM),scanning tunneling spectroscopy(STS),density functional theory(DFT)calculations,and transient absorption(TA)spectroscopy.The results show that BTID-1F and BTID-2F form bright strip structures,whereas BTID-nF(n=1,2)/PC71BM form ridge-like structures with each complex composed of one BTID-nF(n=1,2)molecule and four PC71BM molecules which adsorbed around the BTID-nF(n=1,2)molecule by S···πinteraction.With the assistance of S···πinteraction between BTID-nF(n=1,2)and PC71BM,BTID-nF(n=1,2)/PC71BM co-assembled ridge-like structures are more stable than the BTID-nF(n=1,2)ridge structures.To investigate the charge transfer of BTID-nF(n=1,2)/PC71BM system,STS measurements,DFT calculation,and TA spectroscopy are further performed.The results show that charge transfer occurs in BTID-nF(n=1,2)/PC71BM system with the electron transferring from BTID-nF(n=1,2)molecules to PC71BM. | Yuchuan Xiao Linxiu Cheng Xinyu Sui Qi Wang Jie Chen Dan Deng Jianqi Zhang Xuan Peng Xiaokang Li Xunwen Xiao Ke Deng Xinfeng Liu Zhixiang Wei Qingdao Zeng | 2022 | Nano Research2022，15，9： | 0 |
| 15 | Linking ecosystem services and economic development for optimizing land use change in the poverty areas显示文摘For the sustainable development of human beings and society,it is important to conserve the ecosystems and alleviate poverty in the low agricultural productivity or ecologically vulnerable areas.To avoid the decrease in ecosystem services(ES)under the effects associated with reducing poverty,we need to carefully consider the relationship between land use changes and the economic development in economically poor areas.We selected the Lingqiu County as our study area,which is a national impoverished county in China,and analyzed the impact of poverty alleviation efforts on the ecological and economic sustainability in the region through ES evaluation.The results showed that land use change in the Lingqiu County has not changed the ES significantly during 2007-2016.The gross domestic product(GDP)growth rate(15.81%)during 2001-2016,indicates the effectiveness of the poverty alleviation efforts implemented.The rise in the index of ecological and economic relationship during 2001-2016(from 0.2389 to 0.3629)maintains in a harmonious coordination situation.Presently,the value of ES has not been converted to market-based benefits,and therefore,it is indispensable to find a marketplace for ES(in an innovative way)to promote the high-quality sustainable development of a local economy. | Yinan Xu Jianing Wei Zhijun Li Yingxing Zhao Xinyu Lei Peng Sui Yuanquan Chen | 2021 | Ecosystem Health and Sustainability2021，7，1： | 0 |
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