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| 1 | CMIP6和CMIP5模式对中国极端温度的模拟能力的评估显示文摘本文评估了CMIP5和CMIP6模式对中国在1979-2005年期间的极端温度的模拟性能。结果表明:CMIP6模式可以很好地再现年最大日最高气温,年最小日最低气温和霜冻日数的空间分布特征。对于年最大日最高气温,持续暖日日数和暖昼,CMIP6模式间的不确定性相对于CMIP5模式有所降低。并且,CMIP6模式也能表现出观测到的极端温度的趋势。然而,CMIP6模式再现暖昼和冷夜的能力仍然不足,特别是在青藏高原上存在明显的冷偏差或者暖偏差对于某些指数。单个CMIP6或CMIP5模式的模拟能力就不同的指数而有所不同,某些模式的模拟能力较为突出。对于一些来自同一机构不同版本的模式,改进的CMIP6模式与CMIP5模式的模拟结果没有明显差异。多模式中位数平均的模拟效果优于大多数单个模式。 | LUO Neng GUO Yan GAO Zhibo CHEN Kexin CHOU Jieming | 2020 | Atmospheric and Oceanic Science Letters2020，13，6： | 15 |
| 2 | A survey on barrier coverage with sensors显示文摘 | Fan WU Yang GUI Zhibo WANG Xiaofeng GAO Guihai CHEN | 2016 | Frontiers of Computer Science2016，10，6： | 6 |
| 3 | Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer显示文摘Neoantigens are considered to be ultimate target of tumor immunotherapy due to their high tumor specificity and immunogenicity.Dendritic cell(DCs)vaccines based on neoantigens have exciting effects in treatment of some malignant tumors and are a promising therapeutic modality.Lung cancer is a lethal disease with the highest morbidity and mortality rate in the world.Despite the rapid development of targeted therapy and immune checkpoint inhibitors for lung cancer in recent years,their efficacy is still unsatisfactory overall.Therefore,there is an urgent unmet clinical need for lung cancer treatment.Here,we attempted to treat lung cancer using a personalized neoantigen peptide-pulsed autologous DC vaccine and conducted a single-arm,2 medical centers,pilot study initiated by the investigator(ChiCTR-ONC 16009100,NCT02956551).The patients enrolled were patients with heavily treated metastatic lung cancer.Candidate neoantigens were derived from whole-exome sequencing and RNA sequencing of fresh biopsy tissues as well as bioinformatics analysis.A total of 12 patients were enrolled in this study.A total of 85 vaccine treatments were administered with a median value of 5 doses/person(range:3-14 doses/person).In total,12-30 peptide-based neoantigens were selected for each patient.AIl treatment-related adverse events were grade 1-2 and there were no delays in dosing due to toxic effects.The objective effectiveness rate was 25%;the disease control rate was 75%;the median progression-free survival was 5.5 months and the median overall survival was 7.9 months.This study provides new evidence for neoantigen vaccine therapy and new therapeutic opportunities for lung cancer treatment. | Zhenyu Ding Qing Li Rui Zhang Li Xie Yang shu Song Gao Peipei Wang Xiaoqing Su Yun Qin Yuelan Wang Juemin Fang Zhongzheng Zhu Xuyang Xia Guochao Wei Hui Wang Hong Qian Xianling Guo Zhibo Gao Yu Wang Yuquan Wei Qing Xu Heng Xu Li Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，2： | 3 |
| 4 | Pan-cancer analysis of somatic mutations across 21 neuroendocrine tumor types显示文摘 | Yanan Cao Weiwei Zhou Lin Li Jiaqian Wang Zhibo Gao Yiran Jiang Xiuli Jiang Aijing Shan Matthew H. Bailey Kuan-lin Huang Sam Q. Sun Michael D. McLellan Beifang Niu Weiqing Wang Li Ding Guang Ning | 2018 | Cell Research2018，28，5： | 3 |
| 5 | Publisher's note to“Texture engineering of mono-crystalline silicon via alcohol-free alkali solution for efficient PERC solar cells”[J.Energy Chem.71(2022)104-107显示文摘The publisher regrets that the page range of this paper was incorrect due to production error,and we added al-a5 after page 107 to the pdf version to correct this mistake. | Danni Zhang Jiawang Chen Rui Jia Zhibo Gao Ke Tao Longjie Wang Huayun Ge Xinpu Li Xing Li | 2022 | Journal of Energy Chemistry2022，31，8： | 3 |
| 6 | New Zircon U-Pb Age of the Ore-bearing Porphyry from the Kuga Copper Deposit in the Eastern Bangongco–Nujiang Matallogenic Belt, Tibet显示文摘Objective As the third most important copper polymetallic metallogenic belt in Tibet,the Bangongco–Nujiang metallogenic belt(BNMB)has attracted much attention among geoscientists all over the world(Lin Bin et al.,2017a).There are two ore clusters in the western of BNMB,the Duolong giant porphyry-epithermal Cu(Au,Ag)ore cluster and the Ga’erqiong–Galalelarge porphyry- | LIN Bin SONG Yang LIU Zhibo LIU Zhenyu GAO Yiming | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 3 |
| 7 | Petrogenesis and Tectonic Significance of the Three-Period Porphyries from the Daruoluolong Cu(Au) Deposit, Tibet, China显示文摘The Daruoluolong deposit is the first high-grade Cu(Au) deposit discovered in the middle section of theBangonghu-Nujiang (herein after referred to as Ban-Nu)metallogenic belt, which has not been documented aboutpreviously. This deposit is located in Shuanghu County ofnorthern Tibet, and its geotectonic position belongs to thenorthern margin of the Ban-Nu suture and southern marginof the Qiangtang terrane. There are three-periodporphyries including ore-bearing granodiorite porphyry,barren granite porphyry and biotite granodiorite porphyryin the deposit. In this paper, we present new zircon U-Pbdate, petrogeochemistry, and Hf isotopic compositions toassess host rock and mineralization age, rock type andmagma source. We have also discussed the metallogenicbackground of the Daruoluolong deposit which isconsistent with that of Naruo the deposit in the westernsection of the Ban-Nu metallogenic belt (Ding Shuai et al.,2017). | GAO Ke SONG Yang LIU Zhibo FANG Xiang LI Faqiao LI Haifeng | 2018 | Acta Geologica Sinica(English Edition)2018，92，3： | 2 |
| 8 | Identi-fication and characterization of the causal agent of bacterialcanker of kiwifruit in the Shaanxi Province of China 显示文摘 | ZHAO Zhibo’GAO Xiaoning HUANG Qiling ef al | 2013 | Journal of Plant Pathology2013，95，1： | 1 |
| 9 | Burch colposuspension for stress urinary incontinence: a 14-year prospective follow-up显示文摘We aimed to evaluate the long-term effectiveness and safety of Burch colposuspension(BC) for stress urinary incontinence(SUI). In this prospective cohort study, 84 patients with SUI undergoing BC were enrolled from February 2004 to January 2010.Data on long-term subjective success and postoperative complications were collected at clinic visits and by telephone follow-up.During a mean follow-up period of 14.2 years, 68%(57/84) patients completed the follow-up. A total of 68.4% of patients(39/57) reported absence of SUI symptoms, 73.6%(42/57) were subjectively satisfied according to the Patient Global Impression of Improvement, and 68.4%(39/57) reported subjective success regarding urinary symptoms via the Urinary Distress Inventory Short Form. However, 28.1%(16/57) suffered at least one long-term postoperative complication and incident. Specifically, 1 in25(4.0%) sexually active patients reported dyspareunia, 3 patients(5.3%) had de novo overactive bladder, and 6 patients(10.5%)reported voiding dysfunction. Four patients(7.0%) reported new onset prolapse symptoms, and 3 patients(5.3%) underwent secondary urinary incontinence surgery. Our study indicated that Burch colposuspension is an effective procedure for SUI, and the cure effect was largely maintained for the 14-year follow-up period, with relatively low complication rates. BC should be considered a surgical option for SUI. | Yang Ye Yuan Wang Weijie Tian Zhibo Zhang Shuo Liang Xiaochen Song Jianbin Guo Qianqian Gao Honghui Shi Zhijing Sun Juan Chen Jinghe Lang Lan Zhu | 2022 | Science China(Life Sciences)2022，65，8： | 1 |
| 10 | Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma显示文摘 | Devendra Singh Joseph Minhow Chan Pietro Zoppoli Francesco Niola Ryan Sullivan Angelica Castano Eric Minwei Liu Jonathan Reichel Paola Porrati Serena Pellegatta Kunlong Qiu Zhibo Gao Michele Ceccarelli Riccardo Riccardi Daniel J. Brat Abhijit Guha Ken Ald | 2012 | Science2012，，6099： | 1 |
| 11 | Reinforced Concrete Protective Layer in Construction显示文摘Reinforced concrete structure is widely used in housing construction.In the daily work of our construction project,the control of the physical quality of reinforced concrete structural engineering is a key point.Due to the large amount of reinforced concrete works,we often find that the construction workers have not paid enough attention to the thickness control of the reinforced concrete layer in the concrete structure,resulting in diff erent thickness of the steel protective layer and the displacement of the steel.Coupled with the template size deviation and other factors caused by the protective layer of steel does not meet the requirements,and after pouring concrete,and cannot intuitively see its internal structure,and thus bring the hidden quality of the project.In addition to the raw material quality factors,the deflection of the reinforced protective layer of the reinforced concrete structural members directly affects the mechanical properties and durability of the reinforced concrete members,and the direct relationship between the mechanical properties and the durability of the reinforced concrete structures is directly related to the mechanical properties and the durability of the reinforced concrete structures,safety and service life of buildings.Therefore,the parties involved in the construction and the construction should pay enough attention and concern the protective layer of reinforced concrete structures.Here on the author involved in the construction work since the accumulation of experience and experience,the thickness of reinforced concrete structure protective layer of the views of some views for everyone to explore. | Lijun Gao Xiaojun Zhou Zhibo Xu Changsheng Zhang | 2018 | Insight-Civil Engineering2018，1，1： | 0 |
| 12 | Ultra‑Efficient and Cost‑Effective Platinum Nanomembrane Electrocatalyst for Sustainable Hydrogen Production显示文摘Hydrogen production through hydrogen evolution reaction(HER)offers a promising solution to combat climate change by replacing fossil fuels with clean energy sources.However,the widespread adoption of efficient electrocatalysts,such as platinum(Pt),has been hindered by their high cost.In this study,we developed an easy-to-implement method to create ultrathin Pt nanomembranes,which catalyze HER at a cost significantly lower than commercial Pt/C and comparable to non-noble metal electrocatalysts.These Pt nanomembranes consist of highly distorted Pt nanocrystals and exhibit a heterogeneous elastic strain field,a characteristic rarely seen in conventional crystals.This unique feature results in significantly higher electrocatalytic efficiency than various forms of Pt electrocatalysts,including Pt/C,Pt foils,and numerous Pt singleatom or single-cluster catalysts.Our research offers a promising approach to develop highly efficient and cost-effective low-dimensional electrocatalysts for sustainable hydrogen production,potentially addressing the challenges posed by the climate crisis. | Xiang Gao Shicheng Dai Yun Teng Qing Wang Zhibo Zhang Ziyin Yang Minhyuk Park Hang Wang Zhe Jia Yunjiang Wang Yong Yang | 2024 | Nano-Micro Letters2024，16，6： | 0 |
| 13 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2022 | Research2022，，1： | 0 |
| 14 | Bus Priority Control for Dynamic Exclusive Bus Lane显示文摘One problem with the existing dynamic exclusive bus lane strategies is that bus signal priority strategies with multi-phase priority request at intersections are not adequately considered.The principle of bus signal priority level was designed based on the isolated multi-phase structure principle consideration of the bus signal priority,and a new priority approach for the dynamic exclusive bus lane was proposed.Two types of priority strategies,green extension and red truncation,were proposed for current phase and next phase buses,respectively.The control parameters including minimum green time,green extension time,maximum green time and bus arrival time are calculated.The case studies for this paper were carried out using four consecutive intersections of Huaide Middle Road in Changzhou City.The signal control scheme was designed using the conventional,exclusive bus lane method,the dynamic exclusive bus lane without signal priority method,and the proposed approach,respectively.The authors used the VISSIM simulation platform to evaluate the efficiency of each approach.Results showed that the method of approach can significantly decrease delays caused by social and conventional buses and make up for the negative impact social buses have on the bus rapid transit(BRT)operation,which allows the method to complement the dynamic,exclusive bus lane design. | Zhibo Gao Kejun Long Chaoqun Li Wei Wu Lee.D.Han | 2019 | Computers, Materials & Continua2019，，7： | 0 |
| 15 | Blood cell counting based on U-Net++ and YOLOv5显示文摘Clinical information about a variety of disorders is available through blood cell counting,which is usually done by manual methods.However,manual methods are complex,time-consuming and susceptible to the subjective experience of inspectors.Although many efforts have been made to develop automated blood cell counting algorithms,the complexity of blood cell distribution and the highly overlapping nature of some red blood cells(RBCs) remain significant challenges that limit the improvement of analytical accuracy.Here,we proposed an end-to-end method for blood cell counting based on deep learning.Firstly,U-Net++ was used to segment the whole blood cell image into several regions of interest(ROI),and each ROI contains only one single cell or multiple overlapping cells.Subsequently,YOLOv5 was used to detect blood cells in each ROI.Specifically,we proposed several strategies,including fine classification of RBCs,adaptive adjustment for non-maximal suppression(NMS) threshold and blood cell morphology constraints to improve the accuracy of detection.Finally,the detection outcomes for each ROI were combined and superimposed.The results show that our method can effectively address the issue of high overlap and precisely segment and detect blood cells,with a 98.18% accuracy rate for blood cell counting. | BAI Hua WANG Xuechun GUAN Yingjian GAO Qiang HAN Zhibo | 2023 | Optoelectronics Letters2023，19，6： | 0 |
| 16 | Texture engineering of mono-crystalline silicon via alcohol-free alkali solution for efficient PERC solar cells显示文摘Control of texture structures is an effective method to reduce surface reflectivity and enhance the efficiency of solar cells.In this paper,pyramid structures are prepared on mono-crystalline silicon wafers by cyclodextrin as surfactant to slow down the etching rate in alcohol-free alkali solution.Compared with volatile alcohol surfactant(e.g.isopropanol,IPA),the cyclodextrin not only possesses a relative high boiling point(1534.4℃),but displays non-toxic and biodegradable properties.Furthermore,the surface morphology,average reflectivity,surface recombination of mono-crystalline silicon wafers were studied in detail.The results show that cyclodextrin can decrease the size and depth of pyramid structures,and thus a lower average reflectivity of 7.5%was obtained.In addition,ray tracing simulation was performed to calculate the photo-generated carrier concentration of PN junction with different sizes of pyramids,and the conclusion is that the carrier concentration of small pyramids is much higher than that of large pyramids.Finally,the average efficiency of large-area mono-crystalline silicon PERC solar cells fabricated by cyclodextrin surfactant was 22.69%,which was 0.43%absolutely higher than that of conventional IPA surfactant. | Danni Zhang Jiawang Chen Rui Jia Zhibo Gao Ke Tao Longjie Wang Huayun Ge Xinpu Li Xing Li | 2022 | Journal of Energy Chemistry2022，31，8： | 0 |
| 17 | Comparison of different land-surface perturbation methods in short-range ensemble forecasts显示文摘为了比较不同陆面扰动方法对短时集合预报的影响,本研究设计了陆面模式扰动实验(LSMPE),初始土壤湿度扰动实验(ISMPE),陆面-大气耦合系数扰动实验(LCCPE)以及大气扰动对照实验(GEFSPE).结果表明,在三组陆面扰动实验中,LSMPE能代表最大的不确定性且误差最小;ISMPE的离散度要比LCCPE稍大,但是耦合系数的减弱能有效降低区域平均降水量.然而,所有陆面扰动实验产生的离散度均小于GEFSPE,这表明未来有必要将陆面扰动与大气扰动相结合,以使得模式能代表更多的不确定性. | Zhibo Gao Jiangshan Zhu Yan Guo Xiaodong Yan Xiujuan Wang Huoqing Li Shuwen Li | 2021 | Atmospheric and Oceanic Science Letters2021，14，3： | 0 |
| 18 | 与飞机观测资料对比评估WRF微物理方案集合的模拟能力显示文摘使用WRF模式中的Morrison,WSM6,SBM,P3四种微物理方案的集合,模拟中尺度对流系统降水过程.研究发现不同的微物理方案模拟的对流云区液态含水量,冰水含量的垂直分布各不相同,而模拟的层状云区液态含水量,冰水含量的垂直分布结果相似.总的来说与其他方案相比,Morrison方案和集合平均的结果最接近观测值.我们也注意到在一些区域,所有成员均高估了液态含水量2-8倍,这也导致了在这些区域集合平均值与观测相比仍然有很大的差距. | Yuan Fu Hengchi Lei Jie-fan Yang Zhibo Gao | 2021 | Atmospheric and Oceanic Science Letters2021，14，2： | 0 |
| 19 | Robust Joule-heating ceramic reactors for catalytic CO oxidation显示文摘Joule-heating reactors have the higher energy efficiency and product selectivity compared with the reactors based on radiative heating.Current Joule-heating reactors are constructed with electrically-conductive metals or carbon materials,and therefore suffer from stability issue due to the presence of corrosive or oxidizing gases during high-temperature reactions.In this study,chemicallystable and electrically-conductive(La_(0.80)Sr_(0.20))_(0.95)FeO_(3)(LSF)/Gd_(0.1)Ce_(0.9)O_(2)(GDC)ceramics have been used to construct Joule-heating reactors for the first time.Taking the advantage of the resistance decrease of the ceramic reactors with temperature increase,the ceramic reactors heated under current control mode achieved the automatic adjustment of heating to stabilize reactor temperatures.In addition,the electrical resistance of LSF/GDC reactors can be tuned by the content of the highconductive LSF in composite ceramics and ceramic density via sintering temperature,which offers flexibility to control reactor temperatures.The ceramic reactors with dendritic channels(less than 100μm in diameter)showed the catalytic activity for CO oxidation,which was further improved by coating efficient MnO_(2)nanocatalyst on reactor channel wall.The Joule-heating ceramic reactors achieved complete CO oxidation at a low temperature of 165℃.Therefore,robust ceramic reactors have successfully demonstrated effective Joule heating for CO oxidation,which are potentially applied in other high-temperature catalytic reactions. | Fangsheng LIU Zhibo ZHAO Yuyao MA Yi GAO Jiajie LI Xun HU Zhengmao YE Yihan LING Dehua DONG | 2022 | Journal of Advanced Ceramics2022，11，7： | 0 |
| 20 | High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway显示文摘Chronic inflammation is a crucial inducerof diabetesvascular complications.Onereason is that high glucose easily induces macrophage activation.1 Macrophages are the principal participants in innate immunity and exist in all human tissues.In pathological vascular,infiltrated macrophages secrete inflammatory factors leading to an increase in plaque stability.?In macrophage polarization,autophagy plays an important role.Enhancement of macrophage autophagy could induce macrophage polarization from the M1 phenotype to M2 phenotype and inhibit inflammatory reactions.3 Our previous research found that high glucose condition promotes miR-32 expression and macrophage M1 polarization,4 but the mechanism of miR-32 promoting macrophage M1 polarization is unclear.In this study,we found that,under a high-glucose condition,miR-32/Mef2d/cAMP signaling promoted M1 macrophage polarization via inhibited autophagy.These results provide a theoretical and experimental basis for the prevention and treatment of T2D vascular inflammation. | Cong Chen Jingsong Cao Yan Gao Xiaoping Xie Zhibo Zhao Qing Yuan Yuqi He Xuyu Zu Jianghua Liu | 2024 | Genes & Diseases2024，11，2： | 0 |
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