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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Bone morphogenetic protein-2 is a negative regulator of hepatocyte proliferation downregulated in the regenerating liver显示文摘AIM: To characterize the expression and dynamic changes of bone morphogenetic protein (BMP)-2 in hepatocytes in the regenerating liver in rats after partial hepatectomy (PH), and examine the effects of BMP-2 on proliferation of human Huh7 hepatoma cells. METHODS: Fifty-four adult male Wistar rats were randomly divided into three groups: A normal control (NC) group, a partial hepatectomized (PH) group and a sham operated (SO) group. To study the effect of liver regeneration on BMP-2 expression, rats were sacrificed before and at different time points after PH or the sham intervention (6, 12, 24 and 48 h). For each time point, six rats were used in parallel. Expression and distribution of BMP-2 protein were determined in regenerating liver tissue by Western blot analysis and immunohistochemistry. Effects of BMP-2 on cell proliferation of human Huh7 hepatoma cell line were assessed using an MTT assay.RESULTS: In the normal liver strong BMP-2 expression was observed around the central and portal veins. The expression of BMP-2 decreased rapidly as measured by both immunohistochemistry and Western blot analysis. This decrease was at a maximum of 3.22 fold after 12 h and returned to normal levels at 48 h after PH. No significant changes in BMP-2 immunoreactivity were observed in the SO group. BMP-2 inhibited serum induced Huh7 cell proliferation.CONCLUSION: BMP-2 is expressed in normal adult rat liver and negatively regulates hepatocyte proliferation. The observed down regulation of BMP-2 following partial hepatectomy suggests that such down regulation may be necessary for hepatocyte proliferation. | Cui-Ping Xu Wen-Min Ji Gijs R van den Brink Maikel P Peppelenbosch | 2006 | World Journal of Gastroenterology2006,12,47: | 10 |
| 3 | Management Strategies and Research Orientations of Forest Diseases and Pests in China显示文摘Forest diseases and pests are perceived as a growing hazard to China economy. It is a common conclusion that the actualities of forest pests in china are no effective measures to the old important pests, some secondary pests are ascending to chief pests, increasing devastation from exotic pests, frequent ecological pest eruption induced by environmental detriment and host-leading diseases to threaten the 'Western Development Project 'in China, which is the most important economical strategy to China; th... | ZHANG Xingyao LIANG Jun LU Quan YAN Donghui LUO Youqing XU Zhichun WEN Junbao1. Research Institute of Forest Ecology. Environment and Protection. Chinese Academy of Forestry. Beijing, 100091. P R China:2. College of Biological Sciences and Technology. Beiiine Forestry University. Beiiine. 100083. P R China | 2002 | Chinese Forestry Science and Technology2002,1,2: | 4 |
| 4 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021,29,2: | 3 |
| 5 | 缺血性脑卒中后的中期血压变异性与临床结局的关系显示文摘本研究旨在探讨急性脑卒中患者发病7d内的中期血压变异性(blood pressure variability,BPV)与预后的关系。方法:本研究纳入873例急性缺血性脑卒中患者。通过计算发病7d内的收缩压和舒张压的变异系数来评价中期BPV。 | Wang Y Wang J Meng P Liu N Ji N Zhang G Xu B Zhou X Sun Y Xu Y Hui R He M 陈云 叶鹏 | 2018 | 中华高血压杂志2018,26,5: | 2 |
| 6 | Interaction of insulin receptor substrate 3 with insulin receptor, insulin receptor-related receptor, insulinlike growth factor-1 receptor, and downstream signaling proteins显示文摘 | Xu P Jacobs A R Taylor S I | 1999 | J Biol Chem1999,274,15: | 1 |
| 7 | Topologies for VSC transmission显示文摘 | Andersen B R Xu L Horton P J | 2002 | Power Engineering Journal2002,16,3: | 1 |
| 8 | Mortality and hospitalizations of 24-year-old members of the low-birthweight cohort in northern Finland 显示文摘 | Xu B Rantakallio P Jarvelin M R | 1998 | Epeidemiology1998,9,6: | 1 |
| 9 | VSC transmission operating under unbalanced AC conditions-analysis and control design显示文摘 | Xu L Andersen B R Cartwright P | 2005 | IEEE Trans on Power Delivery2005,20,1: | 1 |
| 10 | Temperature-Dependent Photoluminescence of ZnO Nanorods Prepared by a Simple Solution Route显示文摘 | Lv Y Z Zhang Y H Li C P Ren L R Guo L Xu H B Ding L Yang C L Ge W K and Yang S H | 2007 | Luminescence2007,,: | 1 |
| 11 | A study on the precision of mechanical watch movement with Tourbillon 显示文摘 | Gu Xu P H Ko R Du | 2011 | Journal of Sound and Vibra- tion2011,330,16: | 1 |
| 12 | Effective adsorption of sodium dodecylsulfate (SDS) by hydrocalumite (CaAl-LDH-Cl) induced by self-dissolution and re-precipitation mechanism显示文摘 | Zhang P Qian G R Xu Z P | 2012 | Journal of Colloid and Interface Science2012,367,4: | 1 |
| 13 | High-Rate Precise Point Posi- tioning (PPp) to Measure Seismic Wave Motions: An Ex- perimental Comparison of GPS PPP with Inertial Measurement Units显示文摘 | Xu P Shi C Fang R et ai | 2013 | Journal of Geodesy2013,87,4: | 1 |
| 14 | Power-geometric operators and their use in group decision making 显示文摘 | XU Z S YAGER P R | 2010 | IEEE Transactions on Fuzzy Systems2010,18,1: | 1 |
| 15 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008,,3: | 1 |
| 16 | Synergistic effect of CeO2 modified Pt/C catalysts on the alcohols oxidation显示文摘 | XU C W ZENG R SHEN P K | 2005 | Electrochimica Acta2005,51,: | 1 |
| 17 | Histochemistry and morphology of porcine mast cells 显示文摘 | Xu L R Carr M M Bland A P | 1993 | Histochem J1993,25,: | 1 |
| 18 | Topologies for VSC transmission显示文摘 | Andersen B R Xu L Horton P J | 2002 | Power Engineering Journal2002,21,4: | 1 |
| 19 | Effects of tungsten carbide onelectrochemical properties and microslructural features of AI/Pb-PANI-WC composite inert anodes used in zinc electrowinning 显示文摘 | XU R D HUANG L P ZHOU J F | 2012 | Hydrometallurgy2012,,: | 1 |
| 20 | Post-translational regulation of TGF-β receptor and Smad signaling 显示文摘 | Xu P Liu J Derynek R | 2012 | FEBS let2012,586,14: | 1 |