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| 1 | Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway显示文摘Although cisplatin is one of the chemotherapeutics most frequently used in oral squamous cell carcinoma(OSCC)treatment,it exerts multiple side effects and poor chemosensitivity.Nitrate reportedly demonstrates several beneficial biological functions,and synthesized nitrates enhance the therapeutic efficacy of chemotherapy.However,the role of inorganic nitrate in cisplatin chemotherapy remains unclear.We therefore investigated the effect of inorganic nitrate exerted on cisplatin sensitivity in OSCC.We found that nitrate did not affect OSCC cell growth and apoptosis in OSCC cells and OSCC xenograft tumor animal studies.Cisplatin induced REDD1 expression and AKT activation in OSCC.However,nitrate could increase cisplatin chemosensitivity,reduce its REDD1 expression,and attenuate AKT signaling activation in OSCC cells.Dysregulation of high levels of REDD1,which could enhance AKT activation,was positively associated with poor prognosis in OSCC patients.Thus,reduced REDD1 expression and retarded AKT activation induced by inorganic nitrate might be a new potential approach to the sensitization of oral cancer to cisplatin treatment in the future. | Yuanyong Feng Xuedi Cao Bin Zhao Chunyan Song Baoxing Pang Liang Hu Chunmei Zhang Jinsong Wang Junqi He Songlin Wang | 2021 | Science China(Life Sciences)2021，64，11： | 2 |
| 2 | Hopf bifurcation analysis for a ratio dependent predator-prey system with two delays and stage structure for the predator显示文摘 | DENG Lianwang WANG Xuedi PENG Miao | 2014 | Applied Mathematics and Computation2014，231，15： | 1 |
| 3 | Hopf bifurcation analysis for a ratio-dependent predator–prey system with two delays and stage structure for the predator显示文摘 | Lianwang Deng Xuedi Wang Miao Peng | 2014 | Applied Mathematics and Computation2014，，： | 1 |
| 4 | Hopf bifurcation analysis and amplitude control of the modified Lorenz system显示文摘 | Xuedi Wang Lianwang Deng Wenli Zhang | 2013 | Applied Mathematics and Computation2013，，： | 1 |
| 5 | Hopf Bifurcation Analysis and Amplitude Control of the Modified Lorenz System 显示文摘 | WANG Xuedi DENG Lianwang ZHANG Wenli | 2013 | Applied Mathematics and Computation2013，225，1： | 1 |
| 6 | Hopf bifurcation analysis and amplitude control of the modi-fied Lorenz system 显示文摘 | WANG Xuedi DENG Lianwang ZHANG Wenli | 2013 | Appl Math Comput2013，225，1： | 1 |
| 7 | Tracing control of chaos for the coupled dynamos dynamical system 显示文摘 | Wang Xuedi Tian Lixin | 2004 | Chaos Solitons and Fractals2004，21，： | 1 |
| 8 | The Cymbidium genome reveals the evolution of unique morphological traits显示文摘The marvelously diverse Orchidaceae constitutes the largest family of angiosperms.The genus Cymbidium in Orchidaceae is well known for its unique vegetation,floral morphology,and flower scent traits.Here,a chromosomescale assembly of the genome of Cymbidium ensifolium(Jianlan)is presented.Comparative genomic analysis showed that C.ensifolium has experienced two whole-genome duplication(WGD)events,the most recent of which was shared by all orchids,while the older event was the t event shared by most monocots.The results of MADS-box genes analysis provided support for establishing a unique gene model of orchid flower development regulation,and flower shape mutations in C.ensifolium were shown to be associated with the abnormal expression of MADS-box genes.The most abundant floral scent components identi fied included methyl jasmonate,acacia alcohol and linalool,and the genes involved in the floral scent component network of C.ensifolium were determined.Furthermore,the decreased expression of photosynthesis-antennae and photosynthesis metabolic pathway genes in leaves was shown to result in colorful striped leaves,while the increased expression of MADS-box genes in leaves led to perianth-like leaves.Our results provide fundamental insights into orchid evolution and diversi fication. | Ye Ai Zhen Li Wei-Hong Sun Juan Chen Diyang Zhang Liang Ma Qing-Hua Zhang Ming-Kun Chen Qing-Dong Zheng Jiang-Feng Liu Yu-Ting Jiang Bai-Jun Li Xuedie Liu Xin-Yu Xu Xia Yu Yu Zheng Xing-Yu Liao Zhuang Zhou Jie-Yu Wang Zhi-Wen Wang Tai-Xiang Xie Shan-Hu Ma Jie Zhou Yu-Jie Ke Yu-Zhen Zhou Hsiang-Chia Lu Ke-Wei Liu Feng-Xi Yang Gen-Fa Zhu Laiqiang Huang Dong-Hui Peng Shi-Pin Chen Siren Lan Yves Van de Peer Zhong-Jian Liu | 2021 | Horticulture Research2021，8，1： | 1 |
| 9 | Flow rate measurement method and apparatus of thick pastes显示文摘 | ZHANG Shuangyu WANG Zhinan HAO Xuedi | 2013 | Advanced Materials Research2013，605，： | 1 |
| 10 | Correction: The Cymbidium genome reveals the evolution of unique morphological traits显示文摘After online publication of the article 1 the author noticed minor typo in Fig.4c.CeSEP1/2/3/4 should be read as CeSEP1/3/4.Revised figure supplied during the proof correction was inadvertently not reproduced in the final version.In addition,the affiliation numbers of the authors revised in the original article during proof correction,but not reflected in the title page in Supplementary Information. | Ye Ai Zhen Li Wei-Hong Sun Juan Chen Diyang Zhang Liang Ma Qing-Hua Zhang Ming-Kun Chen Qing-Dong Zheng Jiang-Feng Liu Yu-Ting Jiang Bai-Jun Li Xuedie Liu Xin-Yu Xu Xia Yu Yu Zheng Xing-Yu Liao Zhuang Zhou Jie-Yu Wang Zhi-Wen Wang Tai-Xiang Xie Shan-Hu Ma Jie Zhou Yu-Jie Ke Yu-Zhen Zhou Hsiang-Chia Lu Ke-Wei Liu Feng-Xi Yang Gen-Fa Zhu Laiqiang Huang Dong-Hui Peng Shi-Pin Chen Siren Lan Yves Van de Peer Zhong-Jian Liu | 2021 | Horticulture Research2021，8，1： | 1 |
| 11 | Silencing cathepsin S gene expression inhibits growth, invasion and angiogenesis of human hepatocellular carcinoma in vitro显示文摘 | Qi Fan Xuedi Wang Hanguang Zhang Chuanwei Li Junhua Fan Jing Xu | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 1 |
| 12 | Choledocholithiasis caused by anatomical variation of cystic duct: A case report显示文摘Laparoscopic cholecystectomy(LC)has gradually become the first choice for the treatment of cholecystolithiasis in recent years.Iatrogenic bile duct injury(IBDI)is an important clinical problem in LC.The anatomical variation of the cystic duct increases the probability of IBDI and the difficulty of operation.We present a case of a 44-year-old male with a anatomical variation of the cystic duct complicated with cholecystolithiasis and choledocholithiasis,who successfully underwent choledocholithotomy,choledochoscopic exploration and T-tube drainage surgery.The patient recovered well and was discharged home on postoperative day 10.The T-tube was removed at 1 month postoperatively after cholangiography examination of no choledocholithiasis left. | Meng Tong Yumeng Li Xuedi Sun Yingli Wang Shuai Yang Bocheng Zhang Feiyu Jia Lijun Peng Jinghua Liu | 2022 | Laparoscopic, Endoscopic and Robotic Surgery2022，5，1： | 0 |
| 13 | Enhanced thermoelectric performance of 3D-printed Bi2Te3-based materials via adding Te/Se显示文摘Bi_(2)Te_(3)-based materials were prepared by direct ink writing(DIW)3D printing and their microstructure and thermoelectric properties were investigated with an emphasis on the effect of the content of DMF and Te/Se addition.As the mass ratio of DMF in the composition increased from 6.5%to 8.0%(in mass),the electrical conductivity deteriorated because of the corresponding increased porosity and organic remains in the samples.However,the volatilization of DMF would reduce the fluidity of the slurry.Thus,thermoelectric slurry with 7.0%DMF is the most suitable mass ratio for 3D printing.Additionally,adding Te in the p-type Bi0.4Sb1.6Te3 and adding Se in the n-type Bi2Te2.6Se0.4 have significantly improved their electrical conductivity due to the increased carrier concentration and mobility.Combining with the moderate Seebeck coefficient(~200 mV/K),high power factors with~802 mW·m^(-1)·K^(-2)and 1266 mW·m^(-1)·K^(-2)were obtained for the n-type Bi_(2)Te_(2.6)Se_(0.4)þ10%Se and p-type Bi_(0.4)Sb_(1.6)Te_(3)þ7%Te,respectively,which result in the final relatively high zT values of 0.68 at 573 K and 0.56 at 330 K for ntype and p-type 3D-printed samples. | Xuedi Zhang Jin Chen Han Zhang Pengfei Zhu Rong Wang Fu Li Bo Li | 2023 | Journal of Materiomics2023，9，2： | 0 |
| 14 | Acute effect of twice-daily 15 mA transcranial alternating current stimulation on treatment-resistant depression: a case series study显示文摘Totheeditor:Major depressive disorder(MDD)is a principal cause of disability worldwide and is often associated with high morbidity and mortality rates.Although there are several therapies available for the treatment of depression,about one-third of patients with MMD will not respond to two or more antidepressant drugs with different mechanisms;the patients are then referred to as having treatment-resistant depression(TRD).Patients with TRD have a poorer quality of life,greater economic burden and increased suicidal behaviours.Therefore,new antidepressant treatments that are effective,safe,long-lasting and tolerable are needed.Ketamine infusion,intranasal esketamine and transcranial magnetic stimulation(TMS)have been used to treat early stage TRD.’A recent review suggests that electroconvulsive therapy(ECT)may be superior to ketamine for reducing depression severity in the acute treatment of TRD. | Wenfeng Zhao Huang Wang Haixia Leng Qing Xue Mao Peng Xiukun Jin Liucen Tan Na Pan Xuedi Wang Jie Wang Keming Gao Xiangyang Zhang Hongxing Wang | 2023 | General Psychiatry2023，36，6： | 0 |
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