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| 1 | Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice显示文摘In the present study,we transplanted adipose-derived mesenchymal stem cells into the hippocampi of APP/PS1 transgenic Alzheimer’s disease model mice.Immunofluorescence staining revealed that the number of newly generated(BrdU+)cells in the subgranular zone of the dentate gyrus in the hippocampus was significantly higher in Alzheimer’s disease mice after adipose-derived mesenchymal stem cell transplantation,and there was also a significant increase in the number of BrdU+/DCX+neuroblasts in these animals.Adipose-derived mesenchymal stem cell transplantation enhanced neurogenic activity in the subventricular zone as well.Furthermore,adipose-derived mesenchymal stem cell transplantation reduced oxidative stress and alleviated cognitive impairment in the mice.Based on these findings,we propose that adipose-derived mesenchymal stem cell transplantation enhances endogenous neurogenesis in both the subgranular and subventricular zones in APP/PS1 transgenic Alzheimer’s disease mice,thereby facilitating functional recovery. | Yufang Yan Tuo Ma Kai Gong Qiang Ao Xiufang Zhang Yao Gong | 2014 | Neural Regeneration Research2014，9，8： | 16 |
| 2 | Recent change of the ice core accumulation rates on the Qinghai-Tibetan Plateau显示文摘Three ice cores recovered from the Himalayas (i.e. the East Rongbuk Glacier and the Far East Rongbuk Glacier at Mt. Qomolangma (Everest), and the Dasuopu Glacier at Xixiabangma) show a sharp decline in the accumulation rates since the 1950s, which is consistent with the precipitation fluctuation over India and the low northern latitude zone (5°-35癗). Correspondingly, an increasing trend is observed for the ice core accumulations from the central and northern Qinghai-Tibetan Plateau (i.e. the Xiao Dongkemadi Glacier in the central Tanggula Mountains, the Guliya Ice Cap in the western Kunlun Mountains, and the Dunde Ice Cap in the Qilian Mountains) since the 1950s, which is consistent with the precipitation fluctuation over the middle-high northern latitude zone (35°-70°N). However, the variation magnitude of the high-elevation ice core accumulations is more significant than that of precipitation at the low-eleva- tion places, suggesting its extra sensitivity of high-elevation areas to climatic change. | Shugui Hou Dahe Qin Tandong Yao Dongqi Zhang Tuo Chen | 2002 | Chinese Science Bulletin2002，47，20： | 10 |
| 3 | Effects of Salinity on Embryonic Development, Survival, and Growth of Crassostrea hongkongensis显示文摘This study examined the effects of salinity on embryonic development, survival, and growth of the Hong Kong oyster Crassostrea hongkongensis. The embryos, larvae, and juveniles of C. hongkongensis were held in artificial seawater at three different salinities(low, 15; medium, 23; and high, 30) to determine the optimum hatchery and nursery conditions for mass production of the seeds. Results showed that the percentage production of straight-hinged larvae from fertilized eggs was significantly lower at the high salinity than at the low- and medium-salinities(P < 0.05). The survival rates of larvae and juveniles differed significantly among the three salinity trials, with the highest survival rate observed at the low salinity(P < 0.05). The shell height of larvae was significantly larger at the low salinity than at the high and medium salinities from days 9 to 15(P < 0.05), whereas that of juveniles was significantly larger at the low salinity than at the high and medium salinities on day 70(P < 0.05). These results indicate that the larvae and juveniles of C. hongkongensis are tolerant to a wide range of salinities(15 to 30), but show better growth and survival at relatively low salinities. Thus, it is recommended to use relatively low salinities in hatchery and nursery systems for improved yields of C. hongkongensis. | HUO Zhongming WANG Zhaoping LIANG Jian ZHANG Yuehuan SHEN Jianping YAO Tuo SU Jiaqi YU Ruihai | 2014 | Journal of Ocean University of China2014，13，4： | 6 |
| 4 | Performances of different efficiency calibration methods of high-purity-germanium gamma-ray spectrometry in an inter-comparison exercise显示文摘This study reports the performances of efficiency calibrations for high-purity-germanium gamma-ray spectrometry using the source-, Laboratory Sourceless Object Calibration Software(LabSOCS)-and ANGLE-based methods in an inter-comparison exercise. Although the results of LabSOCS and ANGLE for ^(241)Am emitting lowenergy gamma rays were not very satisfactory, all of the three efficiency calibration methods passed acceptance criteria. The results confirmed the reliability of the calculation codes ANGLE and LabSOCS as alternative efficiency calibration methods in high-purity-germanium gamma spectrometry. This study is likely to promote the further application of the ANGLE and LabSOCS calculation codes in radioactivity measurements. | Bao-Lu Yang Qiang Zhou Jing Zhang Shuai-Mo Yao Ze-Shu Li Wen-Hong Li Fei Tuo | 2019 | Nuclear Science and Techniques2019，30，3： | 5 |
| 5 | Comparison of sequential feeding and continuous feeding on the blood glucose of critically ill patients:a non-inferiority randomized controlled trial显示文摘Background:Glucose control is an important aspect in managing critically ill patients.The goal of this study was to compare the effects of sequential feeding(SF)and continuous feeding(CF)on the blood glucose of critically ill patients.Methods:A non-inferiority randomized controlled trial was adopted in this study.A total of 62 patients who were fed enteral nutritional suspension through gastric tubes were enrolled.After achieving 80%of the nutrition target calories(25 kcal·kg^(-1)·day^(-1))through CF,the patients were then randomly assigned into SF and CF groups.In the SF group,the feeding/fasting time was reasonably determined according to the circadian rhythm of the human body as laid out in traditional Chinese medicine theory.The total daily dosage of the enteral nutritional suspension was equally distributed among three time periods of 7 to 9 o’clock,11 to 13 o’clock,and 17 to 19 o’clock.The enteral nutritional suspension in each time period was pumped at a uniform rate within 2 h by an enteral feeding pump.In the CF group,patients received CF at a constant velocity by an enteral feeding pump throughout the study.Blood glucose values at five points(6:00/11:00/15:00/21:00/1:00)were monitored and recorded for seven consecutive days after randomization.Enteral feeding intolerance was also recorded.Non-inferiority testing was adopted in this study,the chi-square test or Fisher test was used for qualitative data,and the Mann-Whitney U test was used for quantitative data to determine differences between groups.In particular,a repeated measure one-way analysis of variance was used to identify whether changes in glucose value variables across the time points were different between the two groups.Results:There were no significant demographic or physiological differences between the SF and CF groups(P>0.050).The average glucose level in SF was not higher than that in CF(8.8[7.3–10.3]vs.10.7[9.1–12.1]mmol/L,Z=-2.079,P for non-inferiority=0.019).Hyperglycemia incidence of each patient was more common in the CF group than that in the SF group(38.4[19.1–63.7]%vs.11.8[3.0–36.7]%,Z=-2.213,P=0.027).Hypoglycemia was not found in either group.Moreover,there was no significant difference during the 7 days in the incidence of feeding intolerance(P>0.050).Conclusions:In this non-inferiority study,the average blood glucose in SF was not inferior to that in CF.The feeding intolerance in SF was similar to that in CF.SF may be as safe as CF for critically ill patients. | Chang-Jie Ren Bo Yao Miao Tuo Hui Lin Xiang-Yu Wan Xu-Feng Pang | 2021 | Chinese Medical Journal2021，，14： | 3 |
| 6 | Ecological Environment Conservation and Restoration and Sustainable Development of Minqin Oasis显示文摘Minqin oasis in the lower reaches of the Shiyang River is a main natural barrier for the Wuwei Basin. Due to the combined influence of human activities and natural factors in the past half a century, water quality in the lower reaches of the Shiyang River decreased and ecological environment deteriorated, which influenced sustainable development of this area and surrounding area seriously. This paper analyzed current situation and reasons of the deteriorated ecological environment in the lower reaches of the Shiyang River, and proposed that water environment regulation was the primary task in the eco-environment control of Minqin area, specifically,(a) By using existing policies, accelerating the construction of water-saving agriculture in the middle reaches of the Shiyang River, water quantity in the lower reaches would be guanranted, water shortage for agricultural production and ecological use in Minqin oasis would be relieved;(b) Unreasonable human activities such as overexploitation of underground water should be controlled strictly;(c) Water conservancy project should be developed vigorously to ensure rate of flow. It was expected that the above schemes would contribute to the benign circulation of ecological environment in Minqin oasis. | WANG Lide YAO Tuo XU Feng HAN Fugui GUO Chunxiu WANG Fangling Li Faming | 2016 | Journal of Landscape Research2016，8，1： | 2 |
| 7 | Clinical Study of Autologous Cytokine-Induced Killer Cells for the Treatment of Elderly Patients with Diffuse Large B-Cell Lymphoma显示文摘 | Xue-chun Lu Bo Yang Rui-li Yu Xiao-hua Chi Shuai Tuo Chao-wei Tuo Hong-li Zhu Yao Wang Chao-guang Jiang Xiao-bing Fu Yang Yang Yang Liu Shan-qian Yao Han-ren Dai Li-li Cai Bing-jun Li Wei-dong Han | 2012 | Cell Biochemistry and Biophysics2012，，1： | 2 |
| 8 | Interspecific Hybridization Between Crassostrea angulata and C. ariakensis显示文摘Interspecific hybridization can generate heterosis, which is proven to be a useful tool in selective breeding programs for oyster culture. Crassostrea angulata and C. ariakensis are two important economic shellfish species in China. We conducted 2 × 2 reciprocal crosses to determine whether these two species can cross-fertilize and their hybrids can hatch, survive and perform heterosis. Fertilization was found symmetrical without delay. The rate of fertilization success of C. angulata ♀× C. ariakensis ♂ was lower than that of C. ariakensis ♀× C. angulata ♂, and the success rate of both hybridizations was lower than that of two intraspecific crosses each. During the planktonic period, survival rate of the progeny was lower in the hybrid crosses than in the intraspecific crosses. On day 360, mean shell height of the progeny of C. angulata ♀× C. angulata ♂ was highest, which was followed by that of C. angulata ♀× C. ariakensis ♂, C. ariakensis ♀× C. ariakensis ♂ and C. ariakensis ♀× C. angulata ♂ in a descending order. Morphology of adults produced by the hybrid crosses was similar to that of C. angulata. Both hybrids underwent normal gonad development and produced mature gametes in the mating season. This study provided new insights into the quantitative traits in interspecific crosses of Crassostrea species, thus being of guidance value for selective breeding of oyster. | YAO Tuo ZHANG Yuehuan YAN Xiwu WANG Zhaoping LI Dongchun SU Jiaqi YU Ruihai | 2015 | Journal of Ocean University of China2015，14，4： | 2 |
| 9 | MicroRNA-375 promotes 3T3-L adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling显示文摘 | Ling HY Wen GB Feng SD Tuo QH Ou HS Yao CH | 2011 | Clin Exp Pharmacol Physiol2011，38，4： | 1 |
| 10 | Asynchronous Holocene climatic change across China显示文摘 | Y. He Wilfred H. Theakstone Zhang Zhonglin Zhang Dian Yao Tandong Chen Tuo Shen Yongping Pang Hongxi | 2003 | Quaternary Research2003，，1： | 1 |
| 11 | Effects of Starvation on Growth, Survival, and Body Biochemical Composition Among Different Sizes of Manila Clam Ruditapes philippinarum 显示文摘 | YANG Feng YAO Tuo HUO Zhong ming | 2010 | Acta Ecologica Sinica2010，30，3： | 1 |
| 12 | Effects ofstarvation on growth, survival, and body biochemicalcomposition of different sizes of Manila clamRuditapes philippinarum 显示文摘 | Yang Feng Yao Tuo Huo Zhongming | 2010 | Acta Ecologica Sinica2010，30，3： | 1 |
| 13 | On-line preconcentration of trace nickel from electrolytic manganese using minicolumn packed activated carbon for electrothermal atomic absorption spectrometry显示文摘 | Yao Jun Krzysztof Jankowski Tuo Yong Yao Zu-feng Xiao Yi Xiao Song-hua Tan Zhu-zhong | 2004 | Journal of Wuhan University of Technology - Mater Sci Ed2004，，4： | 1 |
| 14 | Solid-phase Extraction of Nickel from Electrolytic Manganese Using 'Sorbent in Syringe'Technique for Electrothermal Atomic Absorption Spectrometry 显示文摘 | YAO J LIU Y TUO Y ZHOU F ZHANG J | 2004 | Canadian Journal of Analytical Sciences and Spectroscopy2004，49，5： | 1 |
| 15 | Performance Study of Ti-Pillared Montmorillonite Nanocomposites显示文摘 | TUO B Y WANG J L YAO Y L | 2014 | Advanced Materials Research2014，，： | 1 |
| 16 | Studies on the growth metabolism of bacillus thuringiensis and its vegetative insecticidal protein engineered strains by mieroealorimetry显示文摘 | Yao J Liu Y Tuo Y | 2006 | Applied Biochemistry and Microbiology2006，42，3： | 1 |
| 17 | Studies on the growthmetabolism of bacillus thuringiensis and its vegetative insecticidalprotein engineered strains by microcalorimetry 显示文摘 | Yao J Liu Y Tuo Y | 2006 | AppliedBiochemistry and Microbiology2006，42，3： | 1 |
| 18 | Observation of regular pulse train in a narrow-band optoelectronic oscillator显示文摘We have experimentally observed a new operating state of a regular pulse train in a narrow-band optoelectronic oscillator(OEO) system, where the direct-current(DC) bias of the Mach-Zehnder modulator is set at the maximum value of the transmission transfer function instead of the usual quadrature point. The observed quasi-steady-state pulse train is distinctly periodic, with a period of 10.5 μs and a center frequency of 10 GHz, and resembles a mode-locked OEO in its waveform. The formation of regular pulses here may arise from the dynamic balance of nonlinearity and narrow-band filter effects, with the transient characteristics of the pulses arising mainly from instabilities between the gain and cavity loss. Our results are of great importance for deepening the understanding of the nonlinear dynamical processes in OEO systems. | ZHAO Chunbo TUO Zhuoyue YAO Jiali HE Yuling ZHAI Shenghua MENG Yansong | 2024 | Optoelectronics Letters2024，20，2： | 0 |
| 19 | Synchronous early gastric and intestinal mucosa-associated lymphoid tissue lymphoma in a Helicobacter pylori-negative patient:A case report显示文摘BACKGROUND Mucosa-associated lymphoid tissue(MALT)lymphoma occurs largely in the digestive tract,with the stomach being the most commonly affected organ,followed by the small intestine,large intestine,and esophagus.It is rarely found in both the stomach and colon.Helicobacter pylori(H.pylori)infection is strongly associated with gastric MALT lymphoma,although there is a small number of H.pylori-negative gastric MALT lymphomas.Diagnosis of MALT lymphoma is challenging because of nonspecific symptoms and diverse presentations of endoscopic findings.CASE SUMMARY We report a case of an asymptomatic patient who during screening endoscopy and was found to have stromal tumor-like submucosal uplift lesions in the stomach body and polypoid lesions in the rectum.After endoscopic resection,the patient was diagnosed with multiple early simultaneous gastrointestinal MALT lymphomas.CONCLUSION This study may help improve our understanding of MALT lymphomas and multifocal lesions treated using early endoscopy. | Sheng-Nian Lu Cheng Huang Ling-Li Li Lian-Jun Di Jin Yao Bi-Guang Tuo Rui Xie | 2022 | World Journal of Clinical Cases2022，10，33： | 0 |
| 20 | The correlated study of hyperuricemia and metabolicsyndromes among males of Han ethnicity in the Xinjiang UygurAutonomous Region,China显示文摘This study investigates the relationship between hyperuricemia and metabolic syndrome(MS)among males of Han ethnicity in the Xinjiang Uygur Autonomous Region,China.The blood samples were collected from January to May,2006 in Urumqi.It included 1496 subjects with ages between 20 to 70 years.All these subjects had physical examinations,blood pressure(BP)measurement and analysis for serum uric acid(SUA),fasting blood sugar(FBS),serum triglycer-ide(TG),serum total cholesterol(TC),serum high den-sity lipoprotein(HDL-C)and serum low density lipoprotein(LDL-C)as well as biochemistry assay.The Data were analyzed using the Pearson Chi-Square Test,Independent-Samples T-Test and the Mantel-Haenszel Test for linear trend,respectively.The results show that the prevalence of MS in the present study was 18%.Blood pressure,fasting blood sugar,body mass index(BMI),waist/hip ratio(WHR),TG,TC and LDL-C were significantly higher in the hyperuricemic group than in normal group and these parameters were strongly related to serum uric acid levels.The com-ponents of metabolic syndrome such as obesity,hyper-glycemia,hypertension and dyslipidemia had a close correlation with SUA.The Odds ratios of these meta-bolic diseases in the hyperuricemic group were 3.097 times,2.633 times,2.226 times and 3.058 times of the normal SUA group,respectively.They all have a positive correlation with hyperuricemia.Hyperurice-mia is closely linked to the various components of the metabolic syndrome.More emphasis should be put on the evolving control and prevalence of hyperuricemia and metabolic syndrome among males of Han ethnicity in Xinjiang. | Hua YAO Yuping SUN Qing LI Wenhai YAO Qiuyun WANG Jing HU Gulibaha ABUDUREHEMAN Ling TUO Yan JIANG | 2008 | Frontiers of Medicine2008，2，1： | 0 |
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