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| 1 | Elevated risk of recurrent colorectal neoplasia with Helicobacter pylori?associatedchronic atrophic gastritis: A follow?up study of patients with endoscopicallyresected colorectal neoplasia显示文摘 | Izumi Inoue Jun Kato Noriko Yoshimura Yoshimasa Maeda Kosaku Moribata Naoki Shingaki Hisanobu Deguchi Shotaro Enomoto Takao Maekita Kazuki Ueda Mikitaka Iguchi Hideyuki Tamai Mitsuhiro Fujishiro Nobutake Yamamichi Tatsuya Takeshita Masao Ichinose | 2013 | Molecular and Clinical Oncology2013,,1: | 1 |
| 2 | Overexpression of the miR-34 family suppresses invasive growth of malignantmelanoma with the wild-type p53 gene显示文摘 | Hitoshi Yamazaki Tsuyoshi Chijiwa Yoshimasa Inoue Yoshiyuki Abe Hiroshi Suemizu Kenji Kawai Masatoshi Wakui Daisuke Furukawa Masaya Mukai Sadahito Kuwao Makoto Saegusa Masato Nakamura | 2012 | Experimental and Therapeutic Medicine2012,,5: | 1 |
| 3 | Determination of fluvoxamine and its metabolite fluvoxamino acid by liquid-liquid extraction and column-switching high- performance liquid chromatography 显示文摘 | NORIO YASUI-FURUKORIA YOSHIMASA INOUE SUNAO KANEKO | 2005 | Journal of Pharmaceutical and Biomedical Analysis2005,37,: | 1 |
| 4 | Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease显示文摘AIM: To investigate the effects of Japanese apricot(JA) consumption on gastroesophageal reflux disease(GERD)-related symptoms.METHODS: Participants included individuals living in Minabe-cho,a well-known JA-growing region,who received specific medical check-ups by the local community health service in 2010.GERD-related symptoms were examined in 1303 Japanese individuals using a validated questionnaire,the Frequency Scale for Symptoms of GERD(FSSG),which consists of 7 questions associated with acid reflux symptoms and 5 questions asking about gastrointestinal dysmotility symptoms.Each question was answered using a 4-point scale,with higher scores indicating more severe GERDrelated symptoms.Subjects were divided into two groups according to their intake of dried and pickled JA: daily intake(≥ 1 JA daily)(392 subjects) and none oroccasional intake(< 1 JA daily)(911 subjects).FSSG scores were compared between subjects who consumed JA daily and those who did not.Next,subjects were stratified by age,gender and Helicobacter pylori(H.pylori) status for subanalyses.RESULTS: Those who ate JA daily were significantly older than those who did not(60.6 ± 10.5 years vs 56.0 ± 11.0 years,P < 0.001).Total FSSG scores were significantly lower in subjects with daily JA intake than in those with none or only occasional intake(2.13 ± 3.14 vs 2.70 ± 3.82,P = 0.005).In particular,subjects who consumed JA daily showed significantly improved FSSG dysmotility scores compared with subjects who did not(1.05 ± 1.58 vs 1.46 ± 2.11,P < 0.001).In contrast,the FSSG reflux score did not differ between subjects with and without daily intake of JA(1.08 ± 1.90 vs 1.24 ± 2.11,P = 0.177).Subanalysis indicated that improvement in dysmotility by JA intake was specifically observed in non-elderly(1.24 ± 1.68 vs 1.62 ± 2.22,P = 0.005) and H.pylori-negative subjects(0.99 ± 1.58 vs 1.57 ± 2.06,P < 0.001).GERD patients(total FSSG score ≥ 8) were less frequently observed among subjects with daily intake of JA as compared to those without daily intake of JA(6.1% vs 9.7%,P = 0.040).CONCLUSION: Daily JA intake may improve digestive dysmotility symptoms,resulting in relief of GERD symptoms.The effect is more obvious in non-elderly and H.pylori-negative subjects. | Takao Maekita Jun Kato Shotaro Enomoto Takeichi Yoshida Hirotoshi Utsunomiya Hideyuki Hayashi Toshiko Hanamitsu Izumi Inoue Yoshimasa Maeda Kosaku Moribata Yosuke Muraki Naoki Shingaki Hisanobu Deguchi Kazuki Ueda Mikitaka Iguchi Hideyuki Tamai Masao Ichinose | 2015 | World Journal of Gastroenterology2015,21,26: | 1 |
| 5 | 在屏蔽胃的 mucosal 瘤形成的 Transnasal 和标准 transoral 内视镜检查法显示文摘 AIM: To compare the diagnostic performances of transnasal and standard transoral esophagogastroduodenoscopy (EGD) in gastric cancer screening of asymptomatic healthy subjects. METHODS: Between January 2006 and March 2010, atotal of 3324 subjects underwent examination of the upper gastrointestinal tract by EGD for cancer screening, with 1382 subjects (41.6%) screened by transnasal EGD and the remaining 1942 subjects (58.4%) by standard transoral EGD. Clinical profiles of the screened subjects, detection rates of gastric neoplasia and histopathology of the detected neoplasias were compared between groups according to the stage of Helicobacter pylori (H. pylori )-related chronic gastritis. RESULTS: Clinical profiles of subjects did not differ significantly between the two EGD groups, except that there were significantly more men in the transnasal EGD group. During the study period, 55 cases of gastric mucosal neoplasias were detected. Of these, 23 cases were detected by transnasal EGD and 32 cases by standard transoral EGD. The detection rate for gastric mucosal neoplasia in the transnasal EGD group was thus 1.66%, compared to 1.65% in the standard transoral EGD group, with no significant difference between the two groups. Detection rates using the two endoscopies were likewise comparable, regardless of H. pylori infection. However, detection rates when screening subjects without extensive chronic atrophic gastritis (CAG) were significantly higher with standard transoral EGD (0.70%) than with transnasal EGD (0.12%, P < 0.05). In particular, standard transoral EGD was far better for detecting neoplasia in subjects with H. pylorirelated non-atrophic gastritis, with a detection rate of 3.11% compared to 0.53% using transnasal EGD (P < 0.05). In the screening of subjects with extensive CAG, no significant differences in detection of neoplasia were evident between the two endoscopies, although the mean size of detected cancers was significantly smaller and the percentage of early cancers was significantly higher with standard transoral EGD. CONCLUSION: These results strongly suggest that the diagnostic performance of transnasal endoscopy issuboptimal for cancer screening, particularly in subjects with H. pylori-related non-atrophic gastritis. | Hiroya Nakata Shotaro Enomoto Takao Maekita Izumi Inoue Kazuki Ueda Hisanobu Deguchi Naoki Shingaki Kosaku Moribata Yoshimasa Maeda Yoshiyuki Mori Mikitaka Iguchi Hideyuki Tamai Hiroya Nakata Nobutake Yamamichi Mitsuhiro Fujishiro Jun Kato Masao Ichinose | 2011 | World Journal of Gastrointestinal Endoscopy2011,3,8: | 1 |
| 6 | Frequency and Risk Factors of Various Complications After Computed Tomography–Guided Radiofrequency Ablation of Lung Tumors显示文摘 | Tomohisa Okuma Toshiyuki Matsuoka Akira Yamamoto Yoshimasa Oyama Masami Toyoshima Kenji Nakamura Yuichi Inoue | 2008 | CardioVascular and Interventional Radiology2008,,1: | 1 |
| 7 | Properties of clutch using thixotropic MR fluid with surfactants显示文摘 | Takata Shinzo Hosoo Kenjiro Inoue Yoshimasa | 2007 | Proceedings of SPIE - The International Society for Optical Engineering2007,6423,: | 1 |
| 8 | High Molecular Weight Adiponectin as a Predictor of Long-Term Clinical Outcome in Patients With Coronary Artery Disease显示文摘 | Teruo Inoue Norihiko Kotooka Toshifumi Morooka Hiroshi Komoda Toshihiko Uchida Yoshimasa Aso Toshihiko Inukai Takehiko Okuno Koichi Node | 2007 | The American Journal of Cardiology2007,,4: | 1 |
| 9 | Clinical evaluation of chemosensitivity testing for patients with unresectable non-small cell lung cancer (NSCLC) using collagen gel droplet embedded culture drug sensitivity test (CD-DST)显示文摘 | Masafumi Kawamura Masatoshi Gika Tomohiro Abiko Yoshimasa Inoue Takahiko Oyama Yotaro Izumi Hisayuki Kobayashi Koichi Kobayashi | 2007 | Cancer Chemotherapy and Pharmacology2007,,4: | 1 |
| 10 | Sensitive determination of midazolam and 1 - hydroxymidazolam in plasma by liquid - liquid extraction and column - switching liquid chromatography with ultraviolet absorbance detection and its application for measuring CYP3A activity 显示文摘 | Norio Yasui - Furukori Yoshimasa Inoue Tomonori Tateishi | 2004 | J Chromatogr2004,811,: | 1 |
| 11 | Down regulation of peroxisome proliferator-activated receptorγ expression by inflammatory cytokines and its reversal by thiazolidinediones显示文摘 | T. Tanaka H. Itoh K. Doi Y. Fukunaga K. Hosoda M. Shintani J. Yamashita T.-H. Chun M. Inoue K. Masatsugu N. Sawada T. Saito G. Inoue H. Nishimura Y. Yoshimasa K. Nakao | 1999 | Diabetologia1999,,6: | 1 |
| 12 | High Molecular Weight Adiponectin as a Predictor of Long-Term Clinical Outcome in Patients With Coronary Artery Disease显示文摘 | Teruo Inoue Norihiko Kotooka Toshifumi Morooka Hiroshi Komoda Toshihiko Uchida Yoshimasa Aso Toshihiko Inukai Takehiko Okuno Koichi Node | 2007 | The American Journal of Cardiology2007,,4: | 1 |
| 13 | Radiofrequency Ablated Lesion in the Normal Porcine Lung: Long-Term Follow-Up with MRI and Pathology显示文摘 | Yoshimasa Oyama Kenji Nakamura Toshiyuki Matsuoka Masami Toyoshima Akira Yamamoto Tomohisa Okuma Yoshihiro Ikura Makiko Ueda Yuichi Inoue | 2005 | CardioVascular and Interventional Radiology2005,,3: | 1 |
| 14 | 固溶碳和晶界对超低碳细晶钢应变时效的影响显示文摘我们采用碳含量为1~3 ppm、铁素体晶粒尺寸为9.5 um和183 um的含Nb超低碳钢.在70℃-400℃时效条件下,研究了溶质C和晶界对多晶铁素体钢应变时效现象的影响作用。这种钢呈现出两个明显的硬化阶段。无论是细晶粒试样或是粗晶粒试样,都有第一个硬化阶段,在这个硬化阶段,屈服点YP的增量(△YP】最高达到30 MPa。根据表观活化能和硬化动力学可知,硬化的原因是由于C原子对位错的钉扎。第二个硬化阶段主要表现在细晶粒试样中,伴随着HaJl—Petch系数的增大,△YP也很大,达到了90 MPa。在时效试样中,用透射电镜(rrEM)和三维原子探4t(3DAP)没有检测到细小的析出物。溶质C向晶界的偏析和晶界上Fe原子的扩散是出现第二个硬化阶段的原因。因此,晶界硬化是多晶铁素体钢应变时效硬化的原因。 | Yoshihiko ONO Yoshimasa FUNAKAWA Kaneharu OKUDA Kazuhiro SETO Naoki EBISAWA Koji INOUE Yasuyoshi NAGAI | 2017 | 水钢科技2017,0,4: | 0 |