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| 1 | Zircon U-Pb Ages of the Granodioritic Porphyry in the Laba Molybdenum Deposit,Yunnan,SW China and Its Geological Implication显示文摘Geza 岛弧是一个著名矿化作用集中区域,在西藏的高原的东方边缘的 Sanjiang 领域的部分。在最近的年里,几迟了的 Yanshanian 花岗石的侵入和联系存款在这个区域被发现了,在桃花源,区域是其一最大 Laba 铝存款。以前的研究建议预定 Laba 矿化作用是 85 ±2 妈。然而, granodioritic 斑岩的年龄仍然保持未知。在这研究,从忍受辉钼矿的 granodioritic 斑岩的三件样品锆石标明日期的 LA-ICP-MS U-Pb 与 85.00 ± 的产生日期一起被进行了0.23 妈(MSWD = 0.58 ) , 85.28 ±0.28 妈(MSWD = 1.12 ) ,并且 84.83 ±0.26 妈(MSWD = 0.79 ) 分别地,显示这些 granodioritic 斑岩在 ∼85 附近在迟了的 Yanshanian 形成了妈。与矿化作用的地质的特征结合了,时间地, Laba 存款遗传上空间地与 granodioritic 斑岩被联系。另外, Laba 存款的年龄与另外的迟了的 Yanshanian 侵入和矿化作用一致,建议矿化作用可能在在迟了的白垩纪期间的 intra 板 extensional 环境下面被产生。 | YU Haijun LI Wenchang YIN Guanghou LU Yingxiang CAO Xiaomin HUANG Dingzhu DONG Tao ZHANG Youming | 2014 | Acta Geologica Sinica(English Edition)2014，88，4： | 14 |
| 2 | Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate显示文摘 | Jiezhao Zheng Zhujun Li Rui Tian Youming Lu Xiangyu Guo Yong-hui Jiang Xiao-Jiang Li Yong Q Zhang | 2017 | Cell Research2017，27，10： | 11 |
| 3 | Isolation,purification and characterization of secondary structure of antifreeze protein from Ammopiptanthus mongo-licus显示文摘Antifreeze protein (AFP) from Ammopiptanthus mongolicus leaves was isolated and purified with DEAE cellulose 52, Sephacryl 300, heat treatment and preparative isotachophoresis. The molecular weight of AFP was 50 ku by SDS-PAGE measurement. The average thermal hysteresis activity (THA) of AFP was 0.35℃ at 5 mg/mL using a differential scanning calorimeter (DSC). This AFP showed heated stability. From circular dichroism (CD) of AFP spectral data from 195-240 nm, a well-defined secondary structure of 11% a-helix, 34% antiparallel β-sheet and 55% random coil for the plant AFP was deduced. | FEI Yunbiao WEI Lingbo GAO Suqin LU Manchun WANG Baohuai LI Zhifen ZHANG Youming SHU Nianhong JIANG Yong WANG Weixiang | 2001 | Chinese Science Bulletin2001，46，6： | 8 |
| 4 | Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes显示文摘As an excitatory transmitter system,the glutamatergic transmitter system controls excitability and conductivity of neurons.Since both cardiomyocytes and neurons are excitable cells,we hypothesized that cardiomyocytes may also be regulated by a similar system. | Duanyang Xie Ke Xiong Xuling Su Guanghua Wang Qiang Ji Qicheng Zou Lingling Wang Yi Liu Dandan Liang Jinfeng Xue Luxin Wang Xueting Gao Xingdong Gu Hongyu Liu r Xiaoyu He Li Li Jian Yang Youming Lu Luying Peng Yi-Han Chen | 2021 | Cell Research2021，31，9： | 5 |
| 5 | Selecting pinning nodes to control complex networked systems显示文摘One of the fundamental problems in pinning control of complex networks is selecting appropriate pinning nodes, such that the whole system is controlled. This is particularly useful for complex networks with huge numbers of nodes. Recent research has yielded several pinning node selection strategies, which may be efficient. However, selecting a set of pinning nodes and identifying the nodes that should be selected first remain challenging problems. In this paper, we present a network control strategy based on left Perron vector. For directed networks where nodes have the same in-and out-degrees, there has so far been no effective pinning node selection strategy, but our method can find suitable nodes. Likewise, our method also performs well for undirected networks where the nodes have the same degree. In addition, we can derive the minimum set of pinning nodes and the order in which they should be selected for given coupling strengths. Our proofs of these results depend on the properties of non-negative matrices and M-matrices. Several examples show that this strategy can effectively select appropriate pinning nodes, and that it can achieve better results for both directed and undirected networks. | CHENG ZunShui XIN YouMing CAO JinDe YU XingHuo LU GuoPing | 2018 | Science China(Technological Sciences)2018，61，10： | 4 |
| 6 | A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin Ⅱb显示文摘Dominance hierarchy is a fundamental phenomenon in grouped animals and human beings,however,the underlying regulatory mechanisms remain elusive.Here,we report that an antisense long non-coding RNA(lncRNA)of synapsinⅡ;named as AtLAS,plays a crucial role in the regulation of social hierarchy.AtLAS is decreased in the prefrontal cortical excitatory pyramidal neurons of dominant mice;consistently,silencing or overexpression of AtLAS increases or decreases the social rank,respectively.Mechanistically,we show that AtLAS regulates alternative polyadenylation of synapsinⅡgene and increases synapsin 2b(syn2b)expression.Syn2b reduces AMPA receptor(AMPAR)-mediated excitatory synaptic transmission through a direct binding with AMPAR at the postsynaptic site via its unique C-terminal sequence.Moreover,a peptide disrupting the binding of syn2b with AMPARs enhances the synaptic strength and social ranks.These findings reveal a novel role for lncRNA AtLAS and its target syn2b in the regulation of social behaviors by controlling postsynaptic AMPAR trafficking. | Mei Ma Wan Xiong Fan Hu Man-Fei Deng Xian Huang Jian-Guo Chen Heng-Ye Man Youming Lu Dan Liu Ling-Qiang Zhu | 2020 | Cell Research2020，30，2： | 3 |
| 7 | Determination of ginsenoside compound K in human plasma by liquid chromatography–tandem mass spectrometry of lithium adducts显示文摘Ginsenoside compound K(GCK), the main metabolite of protopanaxadiol constituents of Panax ginseng, easily produces alkali metal adduct ions during mass spectrometry particularly with lithium. Accordingly, we have developed a rapid and sensitive liquid chromatography–tandem mass spectrometric method for analysis of GCK in human plasma based on formation of a lithium adduct. The analyte and paclitaxel(internal standard) were extracted from 50 m L human plasma using methyl tertbutyl ether. Chromatographic separation was performed on a Phenomenex Gemini C18 column(50 mm 2.0 mm; 5 μm) using stepwise gradient elution with acetonitrile–water and 0.2 mmol/L lithium carbonate at a flow rate of 0.5 m L/min. Detection was performed in the positive ion mode using multiple reaction monitoring of the transitions at m/z 629-449 for the GCK-lithium adduct and m/z 860-292 for the adduct of paclitaxel. The assay was linear in the concentration range 1.00–1000 ng/m L(r^2>40.9988)with intra- and inter-day precision of ±8.4% and accuracy in the range of 4.8% to 6.5%. Recovery,stability and matrix effects were all satisfactory. The method was successfully applied to a pharmacokinetic study involving administration of a single GCK 50 mg tablet to healthy Chinese volunteers. | Yunhui Chen Youming Lu Yong Yang Xiaoyan Chen Liang Zhu Dafang Zhong | 2015 | Acta Pharmaceutica Sinica B2015，5，5： | 3 |
| 8 | VGLUT3 neurons in median raphe control the efficacy of spatial memory retrieval via ETV4 regulation of VGLUT3 transcription显示文摘The raphe nucleus is critical for feeding, rewarding and memory. However, how the heterogenous raphe neurons are molecularly and structurally organized to engage their divergent functions remains unknown. Here, we genetically target a subset of neurons expressing VGLUT3. VGLUT3 neurons control the efficacy of spatial memory retrieval by synapsing directly with parvalbumin-expressing GABA interneurons(PGIs) in the dentate gyrus. In a mouse model of Alzheimer's disease(AD mice),VGLUT3→PGIs synaptic transmission is impaired by ETV4 inhibition of VGLUT3 transcription. ETV4 binds to a promoter region of VGLUT3 and activates VGLUT3 transcription in VGLUT3 neurons. Strengthening VGLUT3→PGIs synaptic transmission by ETV4 activation of VGLUT3 transcription upscales the efficacy of spatial memory retrieval in AD mice. This study reports a novel circuit and molecular mechanism underlying the efficacy of spatial memory retrieval via ETV4 inhibition of VGLUT3 transcription and hence provides a promising target for therapeutic intervention of the disease progression. | Aodi He Chen Zhang Xiao Ke Yao Yi Quntao Yu Tongmei Zhang Hongyan Yu Huiyun Du Hao Li Qing Tian Ling-Qiang Zhu Youming Lu | 2022 | Science China(Life Sciences)2022，65，8： | 2 |
| 9 | Strain enhancement for a MoS2-on-GaN photodetector with an Al2O3 stress liner grown by atomic layer deposition显示文摘Strain regulation as an effective way to enhance the photoelectric properties of two dimensional(2D)transition metal dichalcogenides has been widely employed to improve the performance of photovoltaic devices.In this work,tensile strain was introduced in multilayer MoS2 grown on GaN by depositing 3 nm of Al2O3 on the surface.The temperature dependent Raman spectrum shows that the thermal stability of MoS2 is improved by Al2O3.Theoretical simulations confirmed the existence of tensile strain on MoS2 covered with Al2O3,and the bandgap and electron effective mass of six layers of MoS2 decreased due to tensile strain,which resulted in an increase of electron mobility.Due to the tensile strain ffect,the photodetector with the Al2O3 stress liner achieved better performance under the illumination of 365 nm wavelength,including a higher responsivity of 24.6 A/W,photoconductive gain of 520,and external quantum fficiency of 8381%,which are more than twice the corresponding values of photodetectors without Al2O3.Our work provides an effective technical way for improving the performance of 2D material photodetectors. | ZHIWEN LI JIANGLIU LUO SHENGQUN HU QIANG LIU WENJIE Yu YOUMING LU XINKE LIU | 2020 | Photonics Research2020，8，6： | 1 |
| 10 | Hole transport in p-type ZnO films grown by plasma-assisted molecular beam epitaxy显示文摘 | Sun Jianwu Lu Youming Liu Yichun | 2006 | Applied Physics Letters2006，89，23： | 1 |
| 11 | Functionalized lignin by grafting phosphorus-nitrogen improves the thermal stability and flame retardancy of polypropylene显示文摘 | Youming Yu Shenyuan Fu Ping’an Song Xiping Luo Yongming Jin Fengzhu Lu Qiang Wu Jiewang Ye | 2012 | Polymer Degradation and Stability2012，，4： | 1 |
| 12 | Effect of Mg content on the structural and optical properties of Mg_xZn_(1-x)O alloys显示文摘Mgx Zn1–x O thin films with x = 0, 0.11, 0.28, 0.44, 0.51, and 0.65 were grown by plasma-assisted molecular beam epitaxy on (0001) sapphire substrates. X-ray diffraction measurement reveals that phase separation of the Mgx Zn1–x O films occurred at x =0.44 and 0.51. Optical absorption spectra show that the absorption edges of the films shift to high-energy side with increasing Mg contents. In resonant Raman spectra, multiple-order Raman peaks originating from ZnO-like longitudinal optical phonons were observed. Moreover, the blue shift and the full width at half maximum of Raman scattering peaks increase continuously with x increasing from 0 to 0.28, which indicates that Zn is substituted by Mg in hexagonal lattice. | WU ChunXia LU YouMing SHEN DeZhen FAN XiWu | 2010 | Chinese Science Bulletin2010，55，1： | 1 |
| 13 | Observation of table-like magnetocaloric effect and large refrigerant capacity in Nd_(6)Fe_(13)Pd_(1-x)Cu_(x) compounds显示文摘The table-like magnetocaloric effect is significant for the magnetic refrigeration applications above 20 K based on the Ericsson cycle.Herein,we prepared a series of Nd_(6)Fe_(13)Pd_(1-x)Cu_(x)(x=0.05,0.1,0.15)compounds by the arc-melting method.These compounds show the single crystalline phase in the tetragonal Nd_(6)Fe_(13)Si-type structure with the space group I4/mcm.A magnetic phase transition from ferromagnetism to antiferromagnetism and a metamagnetic transition from the antiferromagnetic state to the ferromagnetic state are observed in each of the compounds.The compounds exhibit table-like magnetocaloric effects with large refrigerant capacities.A constantΔSM in a temperature span of 40 K in the Nd_(6)Fe_(13)Pd_(0.85)Cu_(0.15) compound are observed.For a field change of 0–5 T,the peak values of–ΔS_(M) for the Nd_(6)Fe_(13)Pd_(0.95)Cu_(0.05),Nd_(6)Fe_(13)Pd_(0.90)Cu_(0.10),and Nd_(6)Fe_(13)Pd_(0.85)Cu_(0.15) compounds are estimated to be 4.8,4.6 and 4.4 J/(kg·K)with corresponding refrigerant capacity values of 323,331 and 316 J/kg,respectively.The obtained table-like magnetocaloric effects with large refrigerant capacities as well as fairly small thermal and magnetic hysteresis deem these series of compounds good candidates for single-phase magnetic refrigeration based on the Ericsson cycle. | Yusong Du Chaohua Zhang Youming Lu Junqin Li Gang Cheng Jiang Wang Guanghui Rao | 2022 | Journal of Rare Earths2022，40，4： | 1 |
| 14 | Effects of Se-enriched polysaccharides produced by Enterobacter cloacae Z0206 on alloxan-induced diabetic mice显示文摘 | Mingliang Jin Zeqing Lu Ming Huang Youming Wang Yizhen Wang | 2011 | International Journal of Biological Macromolecules2011，，2： | 1 |
| 15 | Functionalized lignin by grafting phosphorus-nitrogen improves the thermal stability and flame retardancy of polypropylene显示文摘 | Youming Yu Shenyuan Fu Ping’an Song Xiping Luo Yongming Jin Fengzhu Lu Qiang Wu Jiewang Ye | 2012 | Polymer Degradation and Stability2012，，4： | 1 |
| 16 | The dependence of emission spectra of rare earth ion on the band-gap energy of Mg x Zn 1? x O alloy显示文摘 | Dongxu Zhao Yichun Liu Dezhen Shen Jiying Zhang Youming Lu Xiwu Fan | 2002 | Journal of Crystal Growth2002，，1： | 1 |
| 17 | Study on the impact of window shades’physical characteristics and opening modes on air conditioning energy consumption in China显示文摘This paper focused on the impact of window shades’physical characteristics and opening modes on annual air conditioning energy consumption of residential buildings in China.Three building models with different window layouts were proposed initially,and then validated by the dimensionless indicator annual energy performance(AEP)to determine the final building model adopted in this study.Harbin,Beijing,Guangzhou,Changsha and Kunming were selected to represent five different climate zones in China.The shading model has taken six physical characteristics of window shades,viz.outer emissivity,inner emissivity,solar transmittance,solar reflectance,thermal infrared transmittance,conductivity and two opening modes,viz.up&down mode as well as left&right mode,into consideration.Besides,the window shades operation schedule was summarized through 949 valid questionnaires.The annual air conditioning energy consumption was calculated via EnergyPlus software,and then the impact of the above different opening modes and parameters on energy use were investigated.The analysis results indicated that the top&bottom opening mode is better than the left&right mode when used in Harbin,and the effect of two different modes in air conditioning energy consumption in Kunming is similar.But in the other three cities,the left and right mode is preferred.Besides,the analysis results of the impact of different physical characteristics on air conditioning energy use in different climate zones could help improve the energy performance of window shades. | Yutong Tan Jinqing Peng Charlie Curcija Rongxin Yin Lu Deng Youming Chen | 2020 | Energy and Built Environment2020，1，3： | 0 |
| 18 | African swine fever in China:Emergence and control显示文摘On August 3,2018,the first outbreak of African swine fever(ASF)was confirmed in Shenyang,Liaoning Province,with the virus belonging to genotype II.As of January 2,2019,100 outbreaks in 23 provinces have been identified(see Fig.1),with 12,701 pigs infected and 9,437 of them dead.Following the National Emergency Guidelines for ASF Control,0.84 million pigs within the three-kilometer radius of the infected premises have been stamped out. | Wang Youming Gao Lu Li Yin Xu Quangang Yang Honglin Shen Chaojian Huang Baoxu | 2019 | Journal of Biosafety and Biosecurity2019，1，1： | 0 |
| 19 | miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice显示文摘Post-stroke depression(PSD)is a serious and common complication of stroke,which seriously afects the rehabilitation of stroke patients.To date,the pathogenesis of PSD is unclear and efective treatments remain unavailable.Here,we established a mouse model of PSD through photothrombosis-induced focal ischemia.By using a combination of brain imaging,transcriptome sequencing,and bioinformatics analysis,we found that the hippocampus of PSD mice had a signifcantly lower metabolic level than other brain regions.RNA sequencing revealed a signifcant reduction of miR34b-3p,which was expressed in hippocampal neurons and inhibited the translation of eukaryotic translation initiation factor 4E(eIF4E).Furthermore,silencing eIF4E inactivated microglia,inhibited neuroinfammation,and abolished the depression-like behaviors in PSD mice.Together,our data demonstrated that insufcient miR34b-3p after stroke cannot inhibit eIF4E translation,which causes PSD by the activation of microglia in the hippocampus.Therefore,miR34b-3p and eIF4E may serve as potential therapeutic targets for the treatment of PSD. | Xiao Ke Manfei Deng Zhuoze Wu Hongyan Yu Dian Yu Hao Li Youming Lu Kai Shu Lei Pei | 2023 | Neuroscience Bulletin2023，39，2： | 0 |
| 20 | Author Correction: A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb显示文摘Correction to:Cell Research http://gffzzd3cc09b8251d45dfs0uqb0uncwckf6uxb.ffgz.tsg.suse.edu.cn/10.1038/s41422-020-0273-1 In the initial published version of this Article,there was an error in author information.Youming Lu(lym@hust.edu.cn)is a co-corresponding author.This correction does not affect the description of the results or the conclusions of this work. | Mei Ma Wan Xiong Fan Hu Man-Fei Deng Xian Huang Heng-Ye Man Youming Lu Dan Liu Ling-Qiang Zhu | 2021 | Cell Research2021，31，5： | 0 |
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