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| 1 | Synthesis of spherical CoAl_2O_4 pigment particles with high reflectivity by polymeric-aerosol pyrolysis显示文摘Spherical cobalt blue particles with good reflectivity characteristics were synthesized by spray pyrolysis. Two different spray solutions were prepared to investigate the differences in the morphology and the reflectivity properties of cobalt blue particles. One was an aqueous solution, and the other was a polycation solution that was obtained by chemically modifying the aqueous solution with NH4OH. The cobalt blue particles prepared with the aqueous solution had an irregular morphology after heat treatment at 1000°C for 2 h. On the contrary, spherical and dense particles were obtained from the polycation solution. The spherical and dense cobalt blue particles showed remarkable improvement in reflectivity compared with that of irregular morphology particles as well as the commercial. | HU Guorong DENG Xinrong CAO Yanbing PENG Zhongdong | 2007 | Rare Metals2007，26，3： | 11 |
| 2 | Carbon nanotube-polypyrrole core-shell sponge and its application as highly compressible supercapacitor electrode显示文摘 | Peixu Li Enzheng Shi Yanbing Yang Yuanyuan Shang Qingyu Peng Shiting Wu Jinquan Wei Kunlin Wang Hongwei Zhu Quan Yuan Anyuan Cao Dehai Wu | 2014 | Nano Research2014，7，2： | 10 |
| 3 | Unique characteristics of the genetics epidemiology of amyotrophic lateral sclerosis in China显示文摘Continual discoveries of new genes and unraveling the genetic etiology in amyotrophic lateral sclerosis(ALS) have provided greater insight into the underlying pathogenesis in motor neuron degeneration, as well as facilitating the disease modeling and the testing of targeted therapeutics. While, the genetic etiology accounted for two-thirds of FALS and approximately 11% of SALS in Caucasians. However, the contributions of these causative genes to ALS vary among different populations. Furthermore, the prominent difference between Chinese population and other ethnics remains a source of ongoing debate. We systemically reviewed genetics literature of Chinese ALS populations and updated the mutation frequencies of the main ALS-implicated genes aiming to determine the genetic features of ALS in Chinese population. We also reviewed the associations between ALSimplicated single nucleotide polymorphisms(SNPs) and the risk of ALS in Chinese population. A total of 116 studies were included in this analysis(86 gene mutation study articles and 30 SNPs study articles). The results showed that the overall gene mutation rates of ALS-related causative genes were 55.0% in familial ALS(FALS) and 11.7% in sporadic ALS(SALS) in Chinese population. In Chinese FALS, the highest mutation frequency was found in SOD1 gene(25.6%), followed by FUS(5.8%), TARDBP(5.8%), DCTN1(3.6%) and C9 orf 72(3.5%). In Chinese SALS, the highest mutation frequency was also identified in SOD1 gene(1.6%), followed by ANXA11(1.4%), FUS(1.3%), SQSTM1(1.0%), OPTN(0.9%) and CCNF(0.8%).The associations between several SNPs and risk of ALS were also reported in Chinese population. The genetic features of ALS in Chinese population are significantly different from those in Caucasian population, indicating an association between genetic susceptibility and origin of population. Further explorations are required to understand the gene complexity of ALS, including the contribution of most minor genes and the molecular mechanisms in ALS pathologies. | Qianqian Wei Xueping Chen Yongping Chen Ruwei Ou Bei Cao Yanbing Hou Lingyu Zhang Hui-Fang Shang | 2019 | Science China(Life Sciences)2019，62，4： | 7 |
| 4 | Preparation of spherical spinel LiCr_(0.04)Mn_(1.96)O_4 cathode materials based on the slurry spray drying method显示文摘Regular spherical chromium doped spinel lithium manganese oxides (LiCr0.04Mn1.96O4) with an average particle size of about 20 μm were prepared by the slurry spray drying process. The materials were compared with non-spherical LiCr0.04Mn1.96O4 materials prepared by the common drying process, and all materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), laser particle analyzer and Brunauer-Emmett-Teller (BET) specific surface area test. Electrochemical performances of these cathode materials were studied by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and Li/LiCr0.04Mn1.96O4 battery test. The results show that the spherical active material is single spinel structure, compact, and with narrow particle size distribution and low BET specific surface area. Compared with the non-spherical material, the spherical material prepared by the spray drying process shows a lower electrochemical impedance, a fewer electrochemical polarization and a better charge/discharge rate capability and capacity retention at elevated temperatures. | JIANG Qinglai HU Guorong PENG Zhongdong DU Ke CAO Yanbing TANG Daichun | 2009 | Rare Metals2009，28，6： | 3 |
| 5 | A precision medicine approach to managing 2019 novel coronavirus pneumonia显示文摘In December 2019,several patients with pneumonia of an unknown cause were detected in Wuhan,China.On 7 January 2020,the causal organism was identified as a new coronavirus,later named as the 2019 novel coronavirus(2019-nCoV).Genome sequencing found the genetic sequence of 2019-nCoV homologous to that of severe acute respiratory syndrome-associated coronavirus.As of 29 January 2020,the virus had been diagnosed in more than 7000 patients in China and 77 patients in other countries.It is reported that both symptomatic and asymptomatic patients with 2019-nCoV can play a role in disease transmission via airborne and contact.This finding has caused a great concern about the prevention of illness spread.The clinical features of the infection are not specific and are often indistinguishable from those of other respiratory infections,making it difficult to diagnose.Given that the virus has a strong ability to spread between individuals,it is of top priority to identify potential or suspected patients as soon as possible—or the virus may cause a serious pandemic.Therefore,a precision medicine approach to managing this disease is urgently needed for detecting and controlling the spread of the virus.In this article,we present such an approach to managing 2019-nCoV-related pneumonia based on the unique traits of the virus recently revealed and on our experience with coronaviruses at West China Hospital in Chengdu,China. | Minjin Wang Yanbing Zhou Zhiyong Zong Zongan Liang Yu Cao Hong Tang Bin Song Zixing Huang Yan Kang Ping Feng Binwu Ying Weimin Li | 2020 | Precision Clinical Medicine2020，3，1： | 3 |
| 6 | Synthesis of LiFePO_4 using FeSO_4·7H_2O byproduct from TiO_2 production as raw material显示文摘As the byproduct of TiO2 industrial production, impure FeSO4·7H2O was used for the synthesis of LiFePO4. With the purified solution of FeSO4·7H2O, FePO4·xH2O was prepared by a normal titration method and a controlled crystallization method, respectively. Then LiFePO4 materials were synthesized by calcining the mixture of FePO4·xH2O, Li2CO3, and glucose at 700°C for 10 h in flowing Ar. The results indicate that the elimination of FeSO4·7H2O impurities reached over 95%, and using FePO4·xH2O prepared by the controlled crystallization method, the obtained LiFePO4 material has fine and sphere-like particles. The material delivers a higher initial discharge specific capacity of 149 mAh·g-1 at a current density of 0.1C rate (1C=170 mA·g-1); the discharge specific capacity also maintains above 120 mAh·g1 after 100 cycles even at 2C rate. Thus, the employed processing is promising for easy control, low cost of raw material, and high electrochemical performance of the prepared material. | PENG Zhongdong CAO Yanbing ZHOU Yulin HU Guorong | 2009 | Rare Metals2009，28，6： | 2 |
| 7 | Direct fabrication of carbon nanotube-graphene hybrid films by a blown bubble method显示文摘有 graphene 的碳 nanotubes (CNT ) 的杂交提供集成两材料的属性的一个有希望的工具,从而创新的普遍申请。这里,我们在场直接由一个吹的水泡方法装配混合 CNT-graphene 电影的一个方法与选择底层退火结合了。我们把 polymethylmethacrylate (PMMA ) 用作聚合矩阵吹包含自我装配的多围的 CNT 数组的水泡,然后由在 Cu 底层上的热退火把水泡电影转变成一部 CNT-graphene 混合电影;PMMA 为在 CNT 网络之中对很少层 graphene 变得单个直到担任碳来源一连续地, hybridized 结构被形成。比作赤裸(non-hybridized ) CNT 联网,混合电影展览改进了电的电导率和结构的完整。我们的方法也启用一节多围的 CNT-Si 太阳能电池的制造,它有高力量变换效率,通过混合 CNT-graphene 结构的集会。 | Shiting Wu Enzheng Shi Yanbing Yang Wenjing Xu Xinyang Li Anyuan Cao | 2015 | Nano Research2015，8，5： | 2 |
| 8 | Surface coating of LiNi 0.8 Co 0.15 Al 0.05 O 2 with LiCoO 2 by a molten salt method显示文摘 | Wanmin Liu Guorong Hu Ke Du Zhongdong Peng Yanbing Cao | 2012 | Surface & Coatings Technology2012，，： | 1 |
| 9 | Synthesis and electrochemical performance of nanostructured LiMnPO_4/C composites as lithium-ion battery cathode by a precipitation technique显示文摘 | CAO Yanbing DUAN Jianguo HU Guorong | 2013 | Electrochim Acta2013，98，： | 1 |
| 10 | Development of a double antibodies sandwich ELISA for the detection of avian leukosis virus subgroup J based on monoclonal antibodies against gp85显示文摘Avian leukosis virus(ALV)belongs to the genus Alpharetrovirus of the family Retroviridae and can cause various types of neoplastic diseases,even mortality in infected chickens[1].ALV is categorized into seven subgroups,including A,B,C,D,E,J,and K,based on the pathogenicity and antibody neutralization characteristics[2].The subgroup E is endogenous and transmitted by Mendelian inheritance.The subgroups A,B,C,D,J,and K are exogenous and oncogenic,transmitted horizontally and vertically and caused different pathological lesions[3].Among them,subgroups A and B were most common in commercial poultry and subgroup J is the major cause for myeloid leukosis and nephromas in broilers.In 1980,ALV subgroup J(ALV-J)was first isolated and identified from infected broilers in Britain.It caused significant economic losses in the poultry industry because of increased myelocytomas and other tumors[4].In China,ALV-J was first detected in broilers in 1999 and,subsequently,spread to other chicken types.Compared to other ALV subgroups,ALV-J has been a serious issue in China poultry industry since 2007.Currently,there is no effective vaccine and drugs against ALV-J infection;thus,early detection and elimination of ALV-positive breeder chickens are key measures to block vertical and horizontal ALV-J transmission.Given the importance of ALV to the poultry industry,many ALV detection methods,including virus isolation,immunofluorescence assays,neutralization tests,reverse transcription polymerase chain reaction(PCR)or real-time fluorescent quantitative PCR-based molecular diagnosis ways,and enzyme-linked immunosorbent assays(ELISA)have been developed.Among them,ELISA is widely used for its efficiency,convenience,and sensitivity.Yun et al.[5]developed an antigen-capture ELISA for the detection of ALV based on highly conserved antigen p27.Yu et al.[6]exploited a colloidal gold test strip specific for the detection of ALV p27 antigen.These antigen capture-based serological detection methods share obviously simple,accurate,and rapid advantages in comparison with conventional time-consuming methods of indirect immunofluorescence assay or neutralization tests.However,it is difficult to identify different subgroups of ALV using p27-coated antibodies. | Lili Cao Panpan Zhao He Ding Nan Wang Xue Zhang Shuxian Yuan Hang Dong Yanbing Guo Xinhua Yao Qinlei Yu Hongze Shao Pengtao Gong | 2021 | Acta Biochimica et Biophysica Sinica2021，53，10： | 1 |
| 11 | The evaluation of metastatic lymph node ratio staging system in gastric cancer显示文摘 | Yanbing Zhou Jizhun Zhang Shougen Cao Yu Li | 2013 | Gastric Cancer2013，，3： | 1 |
| 12 | A Comparison Between the Seventh and Sixth Editions of the American Joint Committee on Cancer/International Union Against Classification of Gastric Cancer显示文摘 | Jizhun Zhang Zhaojian Niu Yanbing Zhou Shougen Cao | 2013 | Annals of Surgery2013，，1： | 1 |
| 13 | In vitro leishmanicidal activity of antimicrobial peptide KDEL against Leishmania tarentolae显示文摘Leishmaniasis,caused by the intracellular protozoan parasite Leishmania,remains an important neglected tropical infectious disease.Infection may be lethal if untreated.Currently,the available drugs for the disease are limited by high toxicity and drug resista nee.There is an urgent n eed to develop novel anti-leishmanial strategies.Antimicrobial peptides(AMPs)have been described as the first-line immune defense against pathogenic microbes and are being developed as emerging anti-parasitic therapies.In the present study,we showed the anti-leishmanial activity of the synthetic 4-amino acid peptide lysine,aspartic acid,glutamic acid,and leucine(KDEL),the endoplas?mic reticulum retention sequence,against Leishmania tarentolae promastigote and amastigote.Different concentrations of KDEL peptides were incubated with promastigotes,MTT viability assay,and promastigote assay were carried out.Macrophages infected with GFP-transfected L.tarentolae promastigotes were incubated with KDEL peptides,and the anti-amastigote activity of the KDEL peptides was measured by fluoresce nee microscopy.The damage of L.tarentolae was observed by light microscopy and electron microscopy.The cell apoptosis was analyzed using the Annexin V-FITC/PI apoptosis detection kit and mitochondrial membrane potential assay kit and by flow cytometry.Results showed that L.tarentolae was susceptible to KDEL peptides in a dosedepende nt manner,and KDEL peptides disrupted the surface membrane integrity and caused cell apoptosis.In our study,we found for the first time an AMP KDEL from Pseudomonas aeruginosa and proved its significant therapeutic potential as a novel anti-leishmanial drug. | Lili Cao Weina Jiang Songgao Cao Panpan Zhao Juan Liu Hang Dong Yanbing Guo Quan Liu Pengtao Gong | 2019 | Acta Biochimica et Biophysica Sinica2019，51，12： | 0 |
| 14 | Preparation and electrochemical characteristics of Co_3(PO_4)_2-coated LiNi_(0.8)Co_(0.2)O_2 by solid-state reaction at room temperature显示文摘LiNi0.8Co0.2O2 particles were modified by Co3(PO4)2 coating. The effects of the Co3(PO4)2 coating on the structure and electrochemical properties of the LiNi0.8Co0.2O2 cathode material were investigated. The Co3(PO4)2 coating forms a thin layer on the surface of the LiNi0.8Co0.2O2 material and a solid solution by interacting with the LiNi0.8Co0.2O2 core material during calcination at 700°C for 4 h. Charge-discharge experiment results show that the Co3(PO4)2 coating improves the cycling stability of the LiNi0.8Co0.2O2 cathode material. The capacity retention of the pristine LiNi0.8Co0.2O2 cathode after 50 cycles is 83.6%, whereas it is 91.7% in the case of the LiNi0.8Co0.2O2 cathode coated with 1 wt.% Co3(PO4)2. Storage tests of the 4.35 V charged electrode at 60°C after a month show that the Co3(PO4)2-coated sample exhibits good storage properties compared with the pristine sample. | DENG Xinrong HU Guorong PENG Zhongdong YANG Yanan CAO Yanbing DU Ke | 2008 | Rare Metals2008，27，5： | 0 |
| 15 | Intratumoral Bacteria Dysbiosis Is Associated with Human Papillary Thyroid Cancer and Correlated with Oncogenic Signaling Pathways显示文摘Emerging evidence suggests that microbial dysbiosis plays vital roles in many human cancers.However,knowledge of whether the microbial community in thyroid tumor is related to tumorigenesis remains elusive.In this study,we aimed to explore the microbial community in thyroid tissues and its contribution to papillary thyroid cancer(PTC).In parallel,we performed microbial profiling and transcriptome sequencing in the tumor and adjacent normal tissues of a large cohort of 340 PTC and benign thyroid nodule(BTN)patients.Distinct microbial signatures were identified in PTC,BTN,and their adjacent nontumor tissues.Intra-thyroid tissue bacteria were verified by means of bacteria staining,fluorescence in situ hybridization,and immunoelectron microscopy.We found that 17 bacterial taxa were differentially abundant in PTC compared with BTN,which included enrichment in PTC of the pathobionts Rhodococcus,Neisseria,Streptococcus,Halomonas,and Devosia,and depletion of the beneficial bacteria Amycolatopsis.These differentially abundant bacteria could differentiate PTC tumor tissues(PTC-T)from BTN tissues(BTN-T)with an area under the curve(AUC)of 81.66%.Microbial network analysis showed increased correlation strengths among the bacterial taxa in PTC-T in comparison with BTN-T.Immunefunction-corresponding bacteria(i.e.,Erwinia,Bacillus,and Acinetobacter)were found to be enriched in PTC with Hashimoto’s thyroiditis.Moreover,our integrative analysis revealed that the PTC-enriched bacteria had a positive association with key PTC-oncogenic pathway-related genes,including BRAF,KRAS,IRAK4,CTNNB1,PIK3CA,MAP3K7,and EGFR.In conclusion,our results suggest that intratumor bacteria dysbiosis is associated with the thyroid tumorigenesis and oncogenic signaling pathways of PTC. | Shuang Yu Yanqiang Ding Xuejie Wang Siu Kin Ng Siting Cao Weixin Liu Zhuming Guo Yubin Xie Shubin Hong Lixia Xu Xiaoxing Li Jie Li Weiming Lv Sui Peng Yanbing Li Joseph J.Y.Sung Jun Yu Haipeng Xiao | 2023 | Engineering2023，，9： | 0 |
| 16 | Red Blood Cell-Mimic Nanocatalyst Triggering Radical Storm to Augment Cancer Immunotherapy显示文摘Red blood cells(RBCs)have recently emerged as promosing candidates for cancer treatment in terms of relieving tumor hypoxia and inducing oxidative damage against cancer cells,but they are still far from satisfactory due to their limited oxygen transport and reactive oxygen species generation rate in tumor tissue.Herein,artificial RBCs(designated FTP@RBCM)with radical storm production ability were developed for oncotherapy through multidimensional reactivity pathways of Fe-protoporphyrin-based hybrid metal-organic frameworks(FTPs,as the core),including photodynamic/chemodynamic-like,catalase-like and glutathione peroxidase-like activities.Meanwhile,owing to the advantages of long circulation abilities of RBCs provided by their cell membranes(RBCMs),FTP with a surface coated with RBCMs(FTP@RBCM)could enormously accumulate at tumor site to achieve remarkably enhanced therapeutic efficiency.Intriguingly,this ROS-mediated dynamic therapy was demonstrated to induce acute local inflammation and high immunogenic cancer death,which evoked a systemic antitumor immune response when combined with the newly identified T cell immunoglobulin and mucin-containing molecule 3(Tim-3)checkpoint blockade,leading to not only effective elimination of primary tumors but also an abscopal effect of growth suppression of distant tumors.Therefore,such RBC-mimic nanocatalysts with multidimensional catalytic capacities might provide a promising new insight into synergistic cancer treatment. | Jiong Li Sijia Wang Xinyi Lin Yanbing Cao Zhixiong Cai Jing Wang Zhenxi Zhang Xiaolong Liu Ming Wu Cuiping Yao | 2022 | Nano-Micro Letters2022，14，4： | 0 |
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