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| 1 | Fluvial diversity in relation to valley setting in the source region of the Yangtze and Yellow Rivers显示文摘山谷设定的空间分发(旁边地自由,部分限制,或限制) 并且在 Yangtze 和黄河的来源区域的河的形态学被对比并且分析。长江的来源区域被划分成 3 宽广的节(我, II 和 III )基于山谷设定和隧道坡度,与被描绘由的在上游、下游的节限制(一些活动范围部分限制)山谷,当中间的节被描绘与时宽、浅,旁边地自由的山谷。峡在节是突出的我和 III,当编织隧道模式统治节 II 时。由对比,黄河的来源区域基于山谷特征和隧道坡度被划分成 5 宽广的节(节 IV ) 。节我, II 和 IV 是冲积活动范围与主要旁边地自由(一些短活动范围部分限制) 山谷。节 III 和 V 主要被限制或部分限制。更大的词法差异在相对上面的长江的黄河的来源区域是明显的。这包括编织, anabranching,吻合,蜿蜒地流并且笔直地冲积的模式,与在限制活动范围的峡。这个区域的宏消除(举起,坡度,方面,山谷排列和监禁) ,直接连接了到 Qinghai 西藏高原的构造运动,系住到气候, hydrologic 和关於生命的考虑,是在在这个区域的河差异的模式之上的主要控制。 | YU Guo-an LIU Le LI Zhiwei LI Yanfu HUANG Heqing Gary BRIERLEY Brendon BLUE WANG Zhaoyin PAN Baozhu | 2013 | Journal of Geographical Sciences2013，23，5： | 14 |
| 2 | esveratrol inhibits necroptosis by mediating the TNF-α/RIP1/RIP3/MLKL pathway in myocardial hypoxia/reoxygenation injury显示文摘Resveratrol(RES)protects myocardial cells from hypoxia/reoxygenation(H/R)-caused injury.However,the mechanism of this effect has not been clarified.Thus,in this study,we aimed to determine whether RES attenuates H/R-induced cell necroptosis by inhibiting the tumor necrosis factor-alpha(TNF-α)/receptor-interacting protein kinase 1(RIP1)/RIP3/mixed-lineage kinase domain-like(MLKL)signaling pathway.Rat myocardial ischemia/reperfusion(I/R)models and H/R-injured cell models were constructed.Our study showed that myocardial H/R injury significantly increased the levels of TNF-α,RIP1,RIP3,and p-MLKL/MLKL by western blot analysis.Cell viability assay and 4,6-dianmidino-2-phenylindole(DAPI)-propidium iodide staining showed that the cell viability was decreased,and necroptosis was increased after myocardial H/R injury.The expressions of TNF-α,RIP1,RIP3,and p-MLKL/MLKL in H/R myocardial cells treated with different concentrations of RES were significantly downregulated.In addition,we also found that the cell viability was increased and necroptosis was decreased in dose-dependent manners when H/R-injured cells were treated with RES.In addition,the enhanced effect of TNF-αon necroptosis in myocardial H/R-injured cells was improved by RES,and the effect of RES was confirmed in vivo in I/R rats.This study also showed that RES suppresses necroptosis in H9c2 cells,which may occur through the inhibition of the TNF-α/RIP1/RIP3/MLKL signaling pathway.Our data suggest that necroptosis is a promising therapeutic target and may be a promising therapeutic target for the treatment of myocardial I/R injury. | Yongjun Hu Hongwei Pan Jianqiang Peng Jin He Mingxiang Tang Sulan Yan Jingjing Rong Junshan Li Zhaofen Zheng Haijun Wang Yanfu Liu Xin Zhong | 2021 | Acta Biochimica et Biophysica Sinica2021，53，4： | 6 |
| 3 | Predicting protein secondary structure by a support vector machine based on a new cod ing scheme显示文摘 | Wang Longhui Liu Juan Li Yanfu | 2004 | Genome Informatics2004，15，2： | 1 |
| 4 | Effects of sodium ferulate on the ultrarapid delayed rectifier K^+ current in human atrial myocytes显示文摘Objective:To study the effects of sodium ferulate on the ultrarapid delayed rectifier K+ current(IKur) in human atrial myocytes. Methods:Human atrial myocytes were isolated by enzyme dispersion method. IKur in human atrial myocytes were recorded by using the whole cell patch clamp. The changes of IKur were compared in the absence and the presence of sodium ferulate. Results:There was no effect of 0.4 g/L sodium ferulate on I-V relation of IKur. However, 0.4 g/L sodium ferulate inhibited IKur to some degrees at each test pulse. The current densities of IKur at +60 mV decreased from 4.997 ± 0.35 PA/PF to 3.331 ± 0.26 PA/PF(n = 6, P < 0.05). The inhibitory effect was concentration-dependent. IC50 was(0.41±0.03)g/L and the Hill coefficient was 0.95±0.05. Conclusion:Sodium ferulate as a potassium channel blocker can inhibit IKur in human atrial myocytes effectively. | Xiang Gao Kun Liu Jinping Liu Yanfu Wang Changwei Zhang Zhijian Chen Qiutang Zeng Yuhua Liao | 2008 | Journal of Nanjing Medical University2008，22，1： | 1 |
| 5 | Constitutive model- ing on creep deformation for a SnPb-based composite solder rein- forced with microsized Cu particles 显示文摘 | Shi Yaowu Yan Yanfu Liu Jianping | 2010 | Microelectronics Relia- bility2010，50，12： | 1 |
| 6 | Molecular beam epitaxy of superconducting PdTe_2 films on topological insulator Bi_2Te_3显示文摘Majorana fermions have been observed in topological insulator/s-wave superconductor heterostructures. To manipulate Majorana fermions, superconducting materials should be deposited on the surfaces of topological insulators. In this study, highquality superconducting PdTe_2 films are deposited on the topological insulator Bi_2Te_3 surface using molecular beam epitaxy. The surface topography and electronic properties of PdTe_2/Bi_2Te_3 heterostructures are investigated via in situ scanning tunneling microscopy/spectroscopy. Under Te-rich conditions, the Pd atoms presumably form PdTe_2 film on Bi_2Te_3 surface rather than diffuse into Bi_2Te_3. The superconductivity of the PdTe_2/Bi_2Te_3 heterostructure is detected at a transition temperature of ~1.4 K using the two-coil mutual inductance technique. This study proposes a method for fabricating superconducting materials on topological insulator surfaces at low doping levels, paving ways for designing nanodevices that can manipulate Majorana fermions. | HuanYi Xue Hao Yang YanFu Wu Gang Yao Dandan Guan ShiYong Wang Hao Zheng CanHua Liu YaoYi Li JinFeng Jia | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，7： | 1 |
| 7 | Edge-enriched N, S co-doped hierarchical porous carbon for oxygen reduction reaction显示文摘The development of carbon materials with high electrochemical performance for next-generation energy device is emerging, especially N, S co-doped carbon materials have sparked intensive attention. However,the exploration of N, S co-doped carbon with well-defined active sites and hierarchical porous structures are still limited. In this study, we prepared a series of edge-enriched N, S co-doped carbon materials through pyrolysis of thiourea(TU) encapsulated in zeolitic imidazolate frameworks(TU@ZIF) composites,which delivered very good oxygen reduction reaction(ORR) performance in alkaline medium with onset potential of 0.94 V vs. reversible hydrogen electrode(RHE), good stability and methanol tolerance. Density functional theory(DFT) calculations suggested that carbon atoms adjacent to N and S are probable active sites for ORR intermediates in edge-enriched N, S co-doped carbon materials because higher electron density can enhance O_(2)adsorption, lower formation barriers of intermediates, improving the ORR performance comparing to intact N, S co-doped carbon materials. This study might provide a new pathway for improving ORR activity by the integration engineering of edge sites, and electronic structure of heteroatom doped carbon electrocatalysts. | Fangfang Chang Panpan Su Utsab Guharoy Runping Ye Yanfu Ma Huajun Zheng Yi Jia Jian Liu | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
| 8 | Inhibiting NF-κB increases cholesterol efflux from THP-1 derived-foam cells treated with AngⅡ via up-regulating the expression of ATP-binding cassette transporter A1显示文摘Objective: To study the role of nuclear factor-kappa B(NF-κB) in cholesterol efflux from THP-1 derived-foam cells treated with AngiotensinⅡ(AngⅡ). Methods:Cultured THP-1 derived-foam cells were treated with AngⅡ or preincubated with tosyl-phenylalanine chloromethyl-ketone(TPCK) NF-κB inhibitor. The levels of activated NF-κB in the cells were examined by sandwich ELISA. Cellular cholesterol content was studied by electron microscopy scanning and zymochemistry via fluorospectrophotometer and cholesterol efflux was detected by scintillation counting technique. ABCA1 mRNA and protein were quantified by RT-PCR and Western blotting. Results:Addition of TPCK to the cells before AngⅡ stimulation attenuated the response of NF-κB p65 nuclear translocation induced by AngⅡ and showed no peak in foam cells group and caused a reduction in cholesterol content and an increase in cholesterol efflux by 24.1%(P < 0.05) and 41.1%(P < 0.05) respectively,when compared with AngⅡgroup. In accordance,the ABCA1 mRNA and protein were increased by 30% and 19%(P < 0.05) respectively,when compared with AngⅡ group. Conclusion:AngⅡ can down-regulate ABCA1 in THP-1 derived-foam cells via NF-κB,which leads to less cholesterol efflux and the increase of cholesterol content with the consequence of the promotion of atherosclerosis. | Kun Liu Yanfu Wang Zhijian Chen Yuhua Liao Xiang Gao Jian Chen | 2008 | Journal of Nanjing Medical University2008，22，4： | 0 |
| 9 | A Selective and Sensitive Fluorescence Probe for Se(IV) Based on Fluorescence Quenching of Gatifloxacin显示文摘 | LIU Qing HUAN Yanfu ZHENG Qingchuan FEI Qiang FEI Yanqun FAN Qian FENG Guodong SHAN Hongyan | 2016 | Chemical Research in Chinese Universities2016，32，5： | 0 |
| 10 | Single Atom Catalysts in Liquid Phase Selective Hydrogenations显示文摘Single atom catalysts(SACs)offer exceptional atom efficiency,activity,and selectivity for many catalytic systems.In recent years,SACs have demonstrated great potential in liquid phase selective hydrogenation.In this review,we discuss the critical challenge of selective hydrogenation reactions.Meanwhile,we highlight recent achievements in the design and construction of SACs,as well as their application in liquid reactions.Finally,the current issues and future opportunities for development in the field of SACs are given. | MA Yanfu WANG Liwei LIU Jian | 2022 | Chemical Research in Chinese Universities2022，38，5： | 0 |
| 11 | Reactant enrichment in hollow void of Pt NPs@MnOx nanoreactors for boosting hydrogenation performance显示文摘In confined mesoscopic spaces,the unraveling of a catalytic mechanism with complex mass transfer and adsorption processes such as reactant enrichment is a great challenge.In this study,a hollow nanoarchitecture of MnOx-encapsulated Pt nanoparticles was designed as a nanoreactor to investigate the reactant enrichment in a mesoscopic hollow void.By employing advanced characterization techniques,we found that the reactant-enrichment behavior is derived from directional diffusion of the reactant driven through the local concentration gradient and this increased the amount of reactant.Combining experimental results with density functional theory calculations,the superior cinnamyl alcohol(COL)selectivity originates from the selective adsorption of cinnamaldehyde(CAL)and the rapid formation and desorption of COL in the MnOx shell.The superb performance of 95%CAL conversion and 95%COL selectivity is obtained at only 0.5 MPa H2 and 40 min.Our findings showcase that a rationally designed nanoreactor co uld boost catalytic performance in chemoselective hydrogenation,which can be of great aid and potential in various application scenarios. | Yanfu Ma Liwei Wang Wantong Zhao Tianyi Liu Haitao Li Wenhao Luo Qike Jiang Wei Liu Qihua Yang Jun Huang Riguang Zhang Jian Liu GQMax Lu Can Li | 2023 | National Science Review2023，10，10： | 0 |
| 12 | Ultra-thin Body Buried In_(0.35)Ga_(0.65)As Channel MOSFETs with Extremely Low Off-current on Si Substrates显示文摘In this paper, we investigated the electrical properties of the Metal-oxide-semiconductor gate stack of Ti/Al_(2)O_(3)/In P under different annealing conditions. A minimum interface trap density of 3×10^(11) cm^(-2) eV^(-1) is obtained without postmetallization annealing treatment.Additionally, utilizing Ti/Al_(2)O_(3)/In P MOS gate stack,we fabricated ultra-thin body buried In0.35 Ga0.65 As channel MOSFETs on Si substrates with optimized on/off trade-off. The 200 nm gate length device with extremely low off-current of 0.6 n A/μm, and on-off ratio of 3.3×10^(5), is demonstrated by employing buried low indium(In_(0.35) Ga_(0.65) As) channel with In P barrier/spacer device structure, giving strong potential for future highperformance and low-power applications. | WANG Bo DING Peng FENG Ruize WANG Yanfu LIU Xiaoyu SUN Tangyou CHEN Yonghe LIU Xingpeng LI Qi LI Yue LIU Yingbo YIN Yihui ZHAO Hao ZHANG Wei LI Haiou JIN Zhi | 2021 | Chinese Journal of Electronics2021，30，6： | 0 |
| 13 | Fabrication of monodispersed B,N co-doped hierarchical porous carbon nanocages through confined etching to boost electrocatalytic oxygen reduction显示文摘Dual heteroatom-doped carbons have attracted widespread research attention as catalysts in the field of energy storage and conversion due to their unique electronic structures and chemical tunability.In particular,boron and nitrogen co-doped carbon(B,N@C)has shown great potential for photo/electrocatalytic applications.However,more needs to be done for rational designing and regulating the structure of these materials to improve their catalytic performance.Herein,monodispersed hierarchical porous B,N@C nanocages were fabricated by pyrolyzing zeolite imidazole framework(ZIF)which was treated with ammonia borane or boric acid via an integrated double-solvent impregnation and nanocofined-etching method.The treated ZIF-8 provided an essential structural template to achieve B,N co-doped hierarchical structures with micro/meso/macro multimodal pore size distributions.The resultant B,N@C nanocages displayed high catalytic activities for electrochemical oxygen reduction reaction(ORR)in alkaline media,outperforming most carbon-based catalysts,particularly from the perspective of the half-wave potentials.Such high catalytic performance is due to the enhanced activity by the coexistence of B and N and the mass transfer promoted by the unique hierarchical porous structure. | Xuefei Wang Chao Han Haitao Li Panpan Su Na Ta Yanfu Ma Zhenguo Huang Jian Liu | 2023 | Nano Research2023，16，1： | 0 |
| 14 | Acute ST-elevation myocardial infarction in a patient with polycythemia vera显示文摘To the editor:Little is known about the management of acute myocardial infarction (AMI) in patient with polycythemia vera (PV),especially in those with primary percutaneous coronary intervention (PCI). | Zhang Wei Zhang Yan Liu Yuguo Gokool Indivar Rai Zhang Duoduo Li Pai Kong Jingjing Wang Yanfu Zhou Xuchen | 2014 | Chinese Medical Journal2014，，2： | 0 |
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