|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 2 | Hypoxia inducible factor l alpha regulates T cell receptor signal transduction显示文摘 | Neumann AK Yang J Biju MP et a1 | 2005 | Proc Natl Acad Sci USA2005，102，17： | 1 |
| 3 | CD4+ T lymphocytes mediate acute pulmonary ischemia-reperfusion injury显示文摘 | Yang Z Sharma AK Linden J | | 0，，03： | 1 |
| 4 | Early-onset stroke and vasculopaty associated with mutations in ADA2显示文摘 | Zhou Q Yang D Ombrello AK | 2014 | N Engl J Med2014，370，： | 1 |
| 5 | Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism 显示文摘 | CHEN L YANG J DAVEY AK | 2009 | Xenobiotica2009，39，12： | 1 |
| 6 | Protective systems for high-technological facilities against microvibration and earthquake 显示文摘 | Yang JN Agrawal AK | 2000 | Structural Engineering and Mechanics2000，10，： | 1 |
| 7 | MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer显示文摘 | Yang X Iyer AK Singh A | 2015 | Sci Rep2015，5，： | 1 |
| 8 | Disrupted signaling and in- hibited regeneration in obese mice with fatty livers : implications for nonalcoholic fatty liver disease pathophysiology 显示文摘 | Yang SQ Lin HZ Mandal AK | 2001 | Hepatology2001，34，41： | 1 |
| 9 | Hypoxia inducible factor l alpha regulates T cell receptor signal transduction显示文摘 | Neumann AK Yang J Biju MP | 2005 | Proc Natl Acad Sci USA2005，，17： | 1 |
| 10 | Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients 显示文摘 | Damjanovic AK Yang Y Glaser R | 2007 | J Immunol2007，179，6： | 1 |
| 11 | Hepatic hyperplasia in noncirrhotic fatty livers显示文摘 | Yang SQ Lin HZ Mandal AK | 2001 | Cancer Res2001，61，： | 1 |
| 12 | Norepinephrine up-regulates the ex- pression of vascular endothelial growth factor, matrix metallopmteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells 显示文摘 | Yang EV Sood AK Chen M | 2006 | Cancer Res2006，66，10： | 1 |
| 13 | Phase 1/2 trial of single-session stereotactic body radiotherapy for previously unirradiated spinal metas- tases显示文摘 | Garg AK Shiu AS Yang J | 2012 | Cancer2012，118，20： | 1 |
| 14 | (2000), Protective systems for high-technology facilities against microvibration and earthquake显示文摘 | Yang J N Agrawal AK | 2000 | Journal of Structure Engineering and Mechanics2000，10，6： | 1 |
| 15 | Effect of Tai Chi on gait and obstacle crossing behaviors in middle - aged adults 显示文摘 | Ramachandran AK Rosengren KS Yang Y Hsiao - Wecksler ET | 2007 | Gait Posture2007，26，2： | 1 |
| 16 | Norepinephrine up-regulates the expression of vascular endothelial growth factor,matrix metal- loproteinase (MMP) -2, and MMP-9 in nasopharyngeal carcinoma tumor cells 显示文摘 | Yang EV Sood AK Chen M | 2006 | Cancer Res2006，66，10： | 1 |
| 17 | Intrathecal gene delivery of glial cell line -derived neurotrophic factor ameliorated paraplegia in rats after spinal ischemia 显示文摘 | Chou AK Yang LC Wu PC | 2005 | Brain Res Mol Brain Res2005，133，2： | 1 |
| 18 | The harvesting and insetting of a chimeric anterolateral thigh flap to reconstruct through and through cheek defects显示文摘 | Liu WW Yang AK | 2011 | Int J Oral Maxillofac Surg2011，40，5： | 1 |
| 19 | Cornparison of three different interface mass transfer models used in the experimental measurement of solvent diffusivity in heavy oil显示文摘 | Tharanivasan AK Yang Chaodong Gu Yongan | 2004 | Journal of Petroleum Science and Engineering2004，44，4： | 1 |
| 20 | In vivo quantitative andqualitative assessment of foreign body giant cell formation onbiomaterials in mice deficient in natural killer lymphocytesubsets* mast cells, or the interleukin-4 receptora and in se-vere combined immunodeficient mice显示文摘 | Yang J Jao B McNally AK | 2014 | J Biomed Mater ResA2014，102，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员