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| 1 | Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro显示文摘Dear Editor,In December 2019,a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan,a city of 11 million people in central China.The initial cases were linked to exposures in a seafood market in Wuhan.1 As of January 27,2020,the Chinese authorities reported 2835 confirmed cases in China's Mainland,including 81 deaths.Additionally,19 confirmed cases were identified in Hong Kong,Macao and Taiwan,and 39 imported cases were identified in Thailand,Japan,South Korea,United States,Vietnam,Singapore,Nepal,France,Australia and Canada.The pathogen was soon identified as a novel coronavirus(2019-nCoV),which is closely related to sever acute respiratory syndrome CoV(SARS-CoV).2 Currently,there is no specific treatment against the new virus.Therefore,identifying effective antiviral agents to combat the disease is urgently needed. | Manli Wang Ruiyuan Cao Leike Zhang Xinglou Yang Jia Liu Mingyue Xu Zhengli Shi Zhihong Hu Wu Zhong Gengfu Xiao | 2020 | Cell Research2020，30，3： | 563 |
| 2 | A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy显示文摘anti-CTLA-4 抗体由阻止 B7-CTLA-4 相互作用接近否定发信号引起肿瘤拒绝,这被假定。在比临床上有效的 dosing 完成的血浆层次更加高的集中,令人惊讶地, anti-CTLA-4 抗体 Ipilimumab 不由 CTLA-4 也不 CTLA-4 绑定堵住任何一 B7 trans-endocytosis 到使不能调动或联系房间的 B7。因而, Ipilimumab 不从人性化的任何一个 CTLA4 基因在树枝状的房间(DC ) 上增加 B7 (Ctla4 h/h ) 或人的 CD34 + 茎重新组成房间的 NSG 老鼠。在 Ctla4 高效地表示人和老鼠 CTLA4 基因,绑在人的 anti-CTLA-4 抗体然而并非老鼠 CTLA-4 的 h/m 老鼠导致 Treg 弄空和 Fc 受体依赖者肿瘤拒绝。堵住的抗体 L3D10 比得上在引起肿瘤拒绝的非阻塞的 Ipilimumab。显著地,输在人类化期间堵住活动的 L3D10 子孙在导致 Treg 弄空和肿瘤拒绝仍然保持充分能干。有效地在淋巴的器官堵住 CD4 T 细胞激活和 de novo CD8 T 细胞 priming 的 Anti-B7 抗体否定地不影响 Ipilimumab 的 immunotherapeutic 效果。因此,临床上有效的 anti-CTLA-4 mAb 由独立于检查点封锁的机制引起肿瘤拒绝但是依赖于主人 Fc 受体。我们为 CTLA-4 检查点的一个重评价的数据电话封锁假设并且为安全、有效的 anti-CTLA-4 mAbs 的下一代提供新卓见。 | Xuexiang Du Fei Tang Mingyue Liu Juanjuan Su Yan Zhang Wei Wu Martin Devenport Christopher A Lazarski Peng Zhang Xu Wang Peiying Ye Changyu Wang Eugene Hwang Tinghui Zhu Ting Xu Pan Zheng Yang Liu | 2018 | Cell Research2018，28，4： | 25 |
| 3 | Quaternary glacier development and the relationship between the climate change and tectonic uplift in the Helan Mountain显示文摘孤立拉长 Helan 山脉山岳的 NE-SW,分开从 Tenggeli 沙漠的 Ordos 高原的适度的草地,是在西方中国学习冰河发展的一个关键位置以及气候的联合条件随着变化构造高举。冰川的地形和存款包括冰斗,山峰,刀口山脉,侧面的冰碛,和终端冰碛在 Helan 山的中间的部分在 2800 m a.s.l 上面散布。这分布显示这曾经是 glaciated 在期间晚第四级。形态学特征证明形成事件的风景的一个清楚的序列发生在整个 Helan 山。实验室光学地刺激了光(OSL ) 和标明日期的加速器团 spectrometry 放射性碳(AMS 14C ) 结果显示冰川的进展的迟了的历史。在 Helan 山的中间的部分的迟了的更新世冰河进展了接近他们的位置至少四次,并且冰川的序列能作为最后一个冰川的周期的中间的阶段被分配(MIS3b, 43.2 ????????? ′ ? 錸? 錸?@ | ZHANG Wei HE MingYue LI YongHua CUI ZhiJiu WANG ZhiLin YU Yang | 2012 | Chinese Science Bulletin2012，57，34： | 14 |
| 4 | Simultaneous virus identification and characterization of severe unexplained pneumonia cases using a metagenomics sequencing technique显示文摘Many viruses can cause respiratory diseases in humans.Although great advances have been achieved in methods of diagnosis,it remains challenging to identify pathogens in unexplained pneumonia(UP) cases.In this study,we applied next-generation sequencing(NGS) technology and a metagenomic approach to detect and characterize respiratory viruses in UP cases from Guizhou Province,China.A total of 33 oropharyngeal swabs were obtained from hospitalized UP patients and subjected to NGS.An unbiased metagenomic analysis pipeline identified 13 virus species in 16 samples.Human rhinovirus C was the virus most frequently detected and was identified in seven samples.Human measles virus,adenovirus B 55 and coxsackievirus A10 were also identified.Metagenomic sequencing also provided virus genomic sequences,which enabled genotype characterization and phylogenetic analysis.For cases of multiple infection,metagenomic sequencing afforded information regarding the quantity of each virus in the sample,which could be used to evaluate each viruses' role in the disease.Our study highlights the potential of metagenomic sequencing for pathogen identification in UP cases. | Xiaohui Zou Guangpeng Tang Xiang Zhao Yan Huang Tao Chen Mingyu Lei Wenbing Chen Lei Yang Wenfei Zhu Li Zhuang Jing Yang Zhaomin Feng Dayan Wang Dingming Wang Yuelong Shu | 2017 | Science China(Life Sciences)2017，60，3： | 14 |
| 5 | Magnetoresistance enhancement and temperature stability of magnetoresistance in La_(1-x)(Sr_(1-y)Na_y)_xMnO_3显示文摘A series of the samples La_(1-x)(Sr_(1-y)Na_y)_xMnO_3(y=0.0,0.2,0.4,0.6,0.8,1.0) were prepared by the solid-state reaction method.Magnetoresistance enhancement and temperature stability of magnetoresistance in the system La_(1-x)(Sr_(1-y)Na_y)_xMnO_3 with unchanged Mn^(3+)/Mn^(4+) ratio through the doping of both monovalent and divalent elements at A site were studied through the measurements of X-ray diffraction(XRD) patterns,resistivity-temperature(ρ-T) curves and magnetoresistance-temperature(MR-T) curves.The results indicate that with the increase of Na doping amount,the peak value of MR increases,and it increases from 12.4% for y=0.2 to 50.6% for y=1.0 in the magnetic field B=0.8 T;ρ-T curves exhibit the double-peak phenomenon,which comes from the competition between the resistivity of surface phase and that of body phase;for the sample of y=0.8,MR increases slowly from 8.3% to 9.4% in the temperature range from 259 to 179 K,and MR is so stable in such a wide temperature range,which provides reference for the research on the temperature stability of MR. | Wang, Guiying Yan, Guoqing Yang, Jie Wang, Wenqi Tang, Yonggang Song, Qixiang Zhang, Mingyu Peng, Zhensheng | 2012 | Rare Metals2012，31，4： | 13 |
| 6 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 7 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 8 | Measuring Tourist’s Water Footprint in a Mountain Destination of Northwest Yunnan, China显示文摘Monitoring and minimizing tourist’s water consumption is essential for the sustainable development of mountain destinations in the world. However, available data and a generally accepted protocol on such measurement are still limited. This study uses water footprint accounting to quantify tourist’s water demand in the Liming valley, a World Heritage site and a rapidly growing tourism destination in Northwest Yunnan, China. Both the water for direct and indirect use is taken into account based on the consumptive behavior of the tourists in the valley. Data were collected through guesthouse monitoring and a tourist survey in the 2005 tourist season. The results indicate that an average tourist leaves behind a footprint of 5.2 m3 on local water resources per day. Food production and waste dilution are the two most important water consumption factors. The results also show tourists consume more water than the local residents on per capita basis. This suggests more commitment is necessary to cope with this stress by individual tourists. Management implications to make water use more sustainable in mountain destinations are derived from this study. | YANG Mingyu Luc HENS Robert DE WULF OU Xiaokun | 2011 | Journal of Mountain Science2011，8，5： | 7 |
| 9 | Low-field magnetoresistance of (1-x)La_(0.6)Dy_(0.1)Sr_(0.3)MnO_3/0.5x (Sb_2O_3) composite system under different sintering temperatures of matrix显示文摘A series of (1-x)La0.6Dy0.1Sr0.3MnO3/0.5x(Sb2O3)(x=0.15) samples were prepared by the solid-state reaction method, and the influence of sintering temperature of the matrix on low-field magnetoresistance of (1-x)La0.6Dy0.1Sr0.3MnO3/0.5x (Sb2O3) was studied through the measurements of X-ray diffraction (XRD) patterns, scanning electron microscope (SEM) image, resistivity-temperature (ρ-T) curves, and magnetoresistance-temperature (MR-T) curves. The results indicate that for the samples with low sintering temperature of the matrix, lowfield magnetoresistance effect appears on the whole temperature range and can be explained by grain boundary effect; for the sample with high sintering temperature of the matrix, intrinsic magnetoresistance peak appears on the high-temperature range, low-field magnetore-sistance effect appears on low temperature range, and the magnetoresistance in the magnetic field of 0.2 T and on the comparatively large temperature range between 280 K and 225 K hardly changes with temperature and remains at 4.8%, which can be explained by the competition between the intrinsic magnetoresistance induced by double-exchange function inside grains and the tunneling magnetoresis-tance (TMR) induced by grain boundary effect. The temperature stability of magnetoresistance is beneficial to the practical applications of MR. | Yang, Jie Yan, Guoqing Wang, Guiying Tang, Yonggang Song, Qixiang Zhang, Mingyu Peng, Zhensheng | 2012 | Rare Metals2012，31，3： | 7 |
| 10 | Uncoupling therapeutic from effects for safer and effective CTLA4 humanized mice immunotherapy-related adverse anti-CTLA-4 antibodies in显示文摘 | Xuexiang Du Mingyue Liu Juanjuan Su Peng Zhang Fei Tang Peiying Ye Martin Devenport Xu Wang Yan Zhang Yang Liu Pan Zheng | 2018 | Cell Research2018，28，4： | 6 |
| 11 | Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy显示文摘It remains unclear why the clinically used anti-CTLA-4 antibodies, popularly called checkpoint inhibitors, have severe immunotherapy-related adverse effects (irAEs) and yet suboptimal cancer immunotherapeutic effects (CITE). Here we report that while irAE-prone Ipilimumab and TremeIgG1 rapidly direct cell surface CTLA-4 for lysosomal degradation, the non-irAE-prone antibodies we generated, HL12 or HL32, dissociate from CTLA-4 after endocytosis and allow CTLA-4 recycling to cell surface by the LRBA-dependent mechanism. Disrupting CTLA-4 recycling results in robust CTLA-4 downregulation by all anti-CTLA-4 antibodies and confers toxicity to a non-irAE-prone anti-CTLA-4 mAb. Conversely, increasing the pH sensitivity of TremeIgG1 by introducing designed tyrosine-to-histidine mutations prevents antibody-triggered lysosomal CTLA-4 downregulation and dramatically attenuates irAE. Surprisingly, by avoiding CTLA-4 downregulation and due to their increased bioavailability, pH-sensitive anti-CTLA-4 antibodies are more effective in intratumor regulatory T-cell depletion and rejection of large established tumors. Our data establish a new paradigm for cancer research that allows for abrogating irAE while increasing CITE of anti-CTLA-4 antibodies. | Yan Zhang Xuexiang Du Mingyue Liu Fei Tang Peng Zhang Chunxia Ai James K. Fields Eric J. Sundberg Olga S. Latinovic Martin Devenport Pan Zheng Yang Liu | 2019 | Cell Research2019，29，8： | 6 |
| 12 | Evaluating Soil Dissolved Organic Matter Extraction Using Three-Dimensional Excitation-Emission Matrix Fluorescence Spectroscopy显示文摘Soil dissolved organic matter(DOM) consists of many organic compounds and plays an important role in contaminant transport in the ecosystem. However, the effects of different extraction conditions on contents of different DOM components are poorly understood.We extracted DOM from three soils using different extraction times, solid to liquid ratios(SLR), and extraction solution(KCl)concentrations, and evaluated the extractions using three-dimensional excitation-emission matrix(EEM) fluorescence spectroscopy.The sum of the contents of the main DOM components(protein-, fulvic-, and humic-like compounds) increased by 0.6–3.5, 2.5–3.9,and 0.11–0.37 times(P < 0.05) when SLR decreased from 1:2 to 1:10, the extraction solution concentration increased from 0.01 to 1.5 mol L^(-1), and extraction time increased from 10 to 300 min, respectively. The three-dimensional EEM fluorescence spectroscopy is a useful tool to characterize the components of DOM and evaluate DOM extraction in soils. | XIE Wenming ZHANG Shanshan RUAN Lin YANG Mingyue SHI Weiming ZHANG Hailin LI Weihua | 2017 | Pedosphere2017，27，5： | 6 |
| 13 | Microstructure evolutions and interfacial bonding behavior of Ni-based superalloys during solid state plastic deformation bonding显示文摘As an advanced solid state bonding process,plastic deformation bonding(PDB)is a highly reliable metallurgical joining method that produces significant plastic deformation at the bonding interface of welded joints through thermo-mechanical coupling.In this study,PDB behavior of IN718 superalloy was systematically investigated by performing a series of isothermal compression tests at various processing conditions.It was revealed that new grains evolved in the bonding area through discontinuous dynamic recrystallization(DDRX)at 1000–1150℃.Electron backscattered diffraction(EBSD)and transmission electron microscopy(TEM)results revealed that the bonding of joints is related with interfacial grain boundary(IGB)bulging process,which is considered as a nucleation process of DRXed grain under different deformation environments.During recrystallization process,the bonded interface moved due to strain-induced boundary migration(SIBM)process.Stored energy difference(caused by accumulation of dislocations at the bonding interface)was the dominant factor for SIBM during DRX.The mechanical properties of the bonded joints were dependent upon the recrystallized microstructure and SIBM ensued during PDB. | Jian Yang Zhang Bin Xu Naeemul Haq Tariq MingYue Sun DianZhong Li Yi Yi Li | 2020 | Journal of Materials Science & Technology2020，42，11： | 6 |
| 14 | The Medium Energy X-ray telescope (ME) onboard the Insight-HXMT astronomy satellite显示文摘The Medium Energy X-ray telescope(ME) is one of the three main telescopes on board the Insight hard X-ray modulation telescope(Insight-HXMT) astronomy satellite. ME contains 1728 pixels of Si-PIN detectors sensitive in 5-30 ke V with a total geometrical area of 952 cm^2. The application specific integrated circuit(ASIC) chip, VA32TA6, is used to achieve low power consumption and low readout noise. The collimators define three kinds of field of views(FOVs) for the telescope, 1°×4°, 4°×4°,and blocked ones. Combination of such FOVs can be used to estimate the in-orbit X-ray and particle background components.The energy resolution of ME is ~3 ke V at 17.8 ke V(FWHM) and the time resolution is 255 μs. In this paper, we introduce the design and performance of ME. | XueLei Cao WeiChun Jiang Bin Meng WanChang Zhang Tao Luo Sheng Yang ChunLei Zhang YuDong Gu Liang Sun XiaoJing Liu JiaWei Yang Xian Li Ying Tan ShaoZhen Liu YuanYuan Du FangJun Lu YuPeng Xu Ju Guan ShuangNan Zhang HuanYu Wang TiPei Li ChengMo Zhang XiangYang Wen JinLu Qu LiMing Song XiaoBo Li MingYu Ge YuPeng Zhou ShaoLin Xiong Shu Zhang YongJie Zhang ZeHao Cheng Fei Zhang MaoShun Li XiaoHua Liang Min Gao EnBo Yang XiaoHang Liu HongWei Liu YiJung Yang Fan Zhang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 5 |
| 15 | Synthesis and enhanced photocatalytic performance of Ag/AgCl/TiO^(2)nanocomposites prepared by ion exchange method显示文摘Ag/AgCl/TiO^(2)nanocomposite was synthesized through the combination of sol-gel process and hydrothermal(HT)method followed by ion exchange method in the paper.Transmission electron microscope,UVevis absorption property and X-ray diffraction were utilized to characterize the morphology,optical absorption property and phase structure of the as-prepared photocatalysts.The morphological and performance studies of Ag/AgCl/TiO^(2)revealed that a well-interconnected mixed phase heterojunction photocatalyst was achieved through as-prepared TiO^(2)and the subsequent ion exchange method.By the degradation of Rhodamine B under xenon lamp,Ag/AgCl/TiO^(2)exhibited a significant enhancement in photocatalytic activity compared with TiO^(2)and Ag/TiO^(2).The band gap of Ag/AgCl/TiO^(2)can reach to 2.53eV compared with 3.22eV of the prepared TiO^(2).Furthermore,the synthesis process and photoreaction mechanisms of TiO^(2),Ag/TiO^(2)and Ag/AgCl/TiO^(2)photocatalysts were proposed.It demonstrated that the enhancement of photocatalytic was mainly due to the reducing of electron-hole recombination in Ag/AgCl/TiO^(2). | Qionglian Yang Mingyu Hu Jun Guo Zhenhua Ge Jing Feng | 2018 | Journal of Materiomics2018，4，4： | 5 |
| 16 | Influence of Preparation Technology on the Structure and Phase Composition of MoSi_2-Mo_5Si_3 /SiC Multi-coating for Carbon/Carbon Composites显示文摘Oxidation protective MoSi 2 -Mo 5 Si 3 /SiC multi-coatings for carbon/carbon composites were prepared by chemical vapor reaction and slurry-sintering method. The influence of preparation technology on the structure and phase composition of the coating was investigated by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD) analyses, and then their relationship was discussed. The results indicate that the Si/Mo ratio of the slurry and sintering processing were two main factors that significantly affected the structure and phase composition of the multi-coating. Appropriate sintering process and relatively high Si/Mo ratio were essential for preparing the multi-coating with dense structure and favorable phase composition. After being sintered at 1723 K for 2 h and with the Si/Mo ratio of the slurry being 4.5 (weight ratio), a dense structure accompanied by favorable phase composition of the coating can be obtained. When heat treated at 2373 K for 1 h, this coating became more compact and continuous. Oxidation tests (performed at 1623 and 1823 K) demonstrated that both of these two obtained multi-coatings exhibited better anti-oxidation property than single layer SiC coating. | Xin Yang Yanhong Zou Qizhong Huang Zhean Su Mingyu Zhang Xin Chang Zhiyong Xie | 2010 | Journal of Materials Science & Technology2010，26，2： | 5 |
| 17 | Responses of ammonia-oxidizing microorganisms to biochar and compost amendments of heavy metals-polluted soil显示文摘Heavy metal pollution affects soil ecological function.Biochar and compost can effectively remediate heavy metals and increase soil nutrients.The effects and mechanisms of biochar and compost amendments on soil nitrogen cycle function in heavy-metal contaminated soils are not fully understood.This study examined how biochar,compost,and their integrated use affected ammonia-oxidizing microorganisms in heavy metal polluted soil.Quantitative PCR was used to determine the abundance of ammonia-oxidizing archaea(AOA)and bacteria(AOB).Ammonia monooxygenase(AMO)activity was evaluated by the enzymelinked immunosorbent assay.Results showed that compost rather than biochar improved nitrogen conversion in soil.Biochar,compost,or their integrated application significantly reduced the effective Zn and Cd speciation.Adding compost obviously increased As and Cu effective speciation,bacterial 16 S rRNA abundance,and AMO activity.AOB,stimulated by compost addition,was significantly more abundant than AOA throughout remediation.Correlation analysis showed that AOB abundance positively correlated with NO_(3)^(-)-N(r=0.830,P<0.01),and that AMO activity had significant correlation with EC(r=-0.908,P<0.01)and water-soluble carbon(r=-0.868,P<0.01).Those seem to be the most vital factors affecting AOB community and their function in heavy metal-polluted soil remediated by biochar and compost. | Mingyue Li Jiachao Zhang Xiao Yang Yaoyu Zhou Lihua Zhang Yuan Yang Lin Luo Qingyun Yan | 2021 | Journal of Environmental Sciences2021，33，4： | 5 |
| 18 | Long-term effects of silver nanoparticles on performance of phosphorus removal in a laboratory-scale vertical flow constructed wetland显示文摘Silver nanoparticles(AgNPs)have been widely used in many fields,which raised concerns about potential threats to biological sewage treatment systems.In this study,the phosphorus removal performance,enzymatic activity and microbial population dynamics in constructed wetlands(CWs)were evaluated under a long-term exposure to Ag NPs(0,50,and 200μg/L)for 450 days.Results have shown that Ag NPs inhibited the phosphorus removal efficiency in a short-term exposure,whereas caused no obviously negative effects from a long-term perspective.Moreover,in the coexisting CW system of Ag NPs and phosphorus,competition exhibited in the initial exposure phase,however,cooperation between them was observed in later phase.Enzymatic activity of acid-phosphatase at the moderate temperature(10–20℃)was visibly higher than that at the high temperature(20–30℃)and CWs with Ag NPs addition had no appreciable differences compared with the control.High-throughput sequencing results indicated that the microbial richness,diversity and composition of CWs were distinctly affected with the extension of exposure time at different Ag NPs levels.However,the phosphorus removal performance of CWs did not decline with the decrease of polyphosphate accumulating organisms(PAOs),which also confirmed that adsorption precipitation was the main way of phosphorus removal in CWs.The study suggested that Ag NPs and phosphorus could be removed synergistically in the coexistence system.This work has some reference for evaluating the influences of Ag NPs on the phosphorus removal and the interrelation between them in CWs. | Juan Huang Jun Xiao Yang Guo Wenzu Guan Chong Cao Chunni Yan Mingyu Wang | 2020 | Journal of Environmental Sciences2020，32，1： | 5 |
| 19 | Effects of alkalinity on interaction between EPS and hydroxy-aluminum with different speciation in wastewater sludge conditioning with aluminum based inorganic polymer flocculant显示文摘Extracellular polymeric substances(EPS)form a stable gel-like structure to combine with water molecules through steric hindrance,making the mechanical dewatering of wastewater sludge considerably difficult.Coagulation/flocculation has been widely applied in improving the sludge dewatering performance,while sludge properties(organic fraction and solution chemistry conditions)are highly changeable and have important effects on sludge flocculation process.In this work,the alkalinity effects on sludge conditioning with hydroxy-aluminum were comprehensively investigated,and the interaction mechanisms between EPS and hydroxy-aluminum with different speciation were unraveled.The results showed that the effectiveness of hydroxy-aluminum conditioning gradually deteriorated with increase in alkalinity.Meanwhile,the polymeric hydroxy-aluminum(Al 13)and highly polymerized hydroxy-aluminum(Al 30)were hydrolysed and converted into amorphous aluminum hydroxide(Al(OH)3),which changed the flocculation mechanism from charge neutralization and complexing adsorption to hydrogen bond interaction.Additionally,both Al 13 and Al 30 showed higher binding capacity for proteins and polysaccharides in EPS than monomeric aluminum and Al(OH)3.Al 13 and Al 30 coagulation changed the secondary structure of proteins in EPS,which caused a gelation reaction to increase molecular hydrophobicity of proteins and consequently sludge dewaterability.This study provided a guidance for optimizing the hydroxy-aluminum flocculation conditioning of sludge with high solution alkalinity. | Weijun Zhang Mingyue Tang Dandan Li Peng Yang Shiwei Xu Dongsheng Wang | 2021 | Journal of Environmental Sciences2021，33，2： | 5 |
| 20 | Precise temporal regulation of Dux is important for embryo development显示文摘Dear Editor,Zygotic genome activation(ZGA)following fertilization is accomplished through a process termed the maternal-to-zygotic transition,during which the maternal RNAs and proteins are degraded and zygotic genome is transcriptionally activated.In mice,minor ZGA occurs from S phase of the zygote to G1 phase of the two-cell(2C)embryo,while major ZGA takes place during the middle-to-late 2C stage with a burst of transcription of totipotent cleavage stage-specific genes and retrotransposons. | Mingyue Guo Yanping Zhang Jianfeng Zhou Yan Bi Junqin Xu Ce Xu Xiaochen Kou Yanhong Zhao Yanhe Li Zhifen Tu Kuisheng Liu Jiaming Lin Peng Yang Shaorong Gao Yixuan Wang | 2019 | Cell Research2019，29，11： | 5 |
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