|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Physical characteristics of Chinese Hakka显示文摘Using standard and internationally validated methods,86 anthropologic characteristics were determined in 650 male(305 from urban areas and 345 from rural areas) and 704 female(331 from urban areas,373 from rural areas) Chinese Hakka adults living in Guangdong and Jiangxi.The data were used to calculate 24 anthropologic indices,which were analyzed statistically.The physical characteristics of Hakka subjects were analyzed and compared with reference ethnic data.There were four main findings of this study.First,a small proportion of Hakka adults had an eye fold on the upper eyelid,but a large proportion had a mongoloid fold.The eye slits were narrow in most adults,had a medium nasal root height and straight bridges,and most of the external angles were prominent.The nasal base was upturned in most men.The distributions of the three types of nasal base in women were similar.The proportions of subjects with middle and high alae nasi heights were high and similar.Males with a maximum nostril diameter were mostly classified as transverse and oblique,while many women were classified as transverse and had relatively wide alae nasi.The round lobe type was the most common.Upper lip skin height was mostly classified as medium.Lips were classified as thin.The hair was black,eyes were brown,and the skin was yellowish.Second,the head length was long in male Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Meanwhile,head breadth,morphological facial height,nose breadth,mouth breadth,and nose height were similar to those of South-Asian populations.Head length was long in female Hakka.The minimum frontal breadth,face breadth,lip height,and interocular breadth were similar to those of North-Asian populations.Head breadth,nose breadth,and mouth breadth were similar to those of South-Asian populations.Third,the stature of male and female Hakka in urban and rural areas was classified as medium.The proportions of male and female Hakka classified as mesocephaly(length-breadth index of the head),hypsicephalic type,metriocephalic type(breadth-height index of the head) mesorrhiny,long trunk,subbrachyskelic type,broad shoulder breadth,and narrow distance between iliac crests were higher than those of other types.Finally,principal component analyses showed that the physical characteristics of Hakka were between those of South-Asian and North-Asian ethnic populations,but were generally closer to those of North-Asian populations in China. | ZHENG LianBin LI YongLan LU ShunHua BAO JinPing WANG Yang ZHANG XiaoRui XUE Hong RONG WenGuo | 2013 | Science China(Life Sciences)2013，56，6： | 13 |
| 2 | National 2000' GPS control network of China显示文摘有超过 2500 个车站的一个精确地统一的国家 GPS 网络,说出“国家 2000' GPS 控制 Netweork ”,签署了时代 2000.0,被集成存在建立了中国的六个全国性的 GPS 网络与不同目的由不同部门建立了。这篇论文论述令人激动的 GPS 网络的特征,在 GPS 网络,包括的功能的模型,随机的模型以及调整的综合调整总结策略原则修正。由根据存在 GPS 网络并且在 IGS 车站的支持下面的特征修改调整策略,综合国家 GPS 网络的精确性极大地被改进。在潜水艇网络之中的资料差别消失,系统的错误影响被削弱,并且估计的坐标和他们的变化上的孤立点的效果被控制。为水平部件的平均标准差当时更小,这被显示出 1.0 厘米,垂直部件比 2.0 厘米小,并且三维(3-D ) geocenter 坐标的位置比 3.0 厘米小。为 3-D 位置的外面的检查精确性比 1.0 厘米平均好。 | Yang Yuanxi Tang Yingzhe Chen Chuanlu Wang Min Zhang Peng Wang Xiaorui Song Lijie Zhang Zusheng | 2007 | Progress in Natural Science:Materials International2007，17，8： | 7 |
| 3 | Flexible and biocompatible nanopaper-based electrode arrays for neural activity recording显示文摘 | Yichuan Guo Zhiqiang Fang Mingde Du Long Yang Leihou Shao Xiaorui Zhang Li Li Jidong Shi Jinsong Tao Jinfen Wang Hongbian Li Ying Fang | 2018 | Nano Research2018，11，10： | 3 |
| 4 | Real-time Raman detection by the cavity mode enhanced Raman scattering显示文摘Integrating surface enhanced Raman scattering (SERS) with microfluidics is the long-term goal for reduced volume,multiplex and automation fingerprint detection of biomolecules.High sensitivity,repeatability,stability,reusability and real-time detection are the performance goals of Raman detection in the aqueous solution environment.Here,we reported the study on cavity mode enhanced SERS detection of both surface-adsorbed molecules and non-surface-adsorbed molecules in the solution environment.The cavity modes had important influence on the SERS enhancement,especially for the non-surface adsorbed molecules.Uniform,repeatable,reusable and real-time Raman signal detection of the non-surface adsorbed Rhodamine 6G molecules was demonstrated.Our work is an important step for the practical on-chip microfluidic Raman detection applications. | Yang Liu Xiaorui Tian Weiran Guo Wenqiang Wang Zhiqiang Guan Hongxing Xu | 2019 | Nano Research2019，12，7： | 2 |
| 5 | Overview of the Mars climate station for Tianwen-1 mission显示文摘The background and scientific objectives of the Mars Climate Station(MCS)for Tianwen-1 are introduced,accompanied by a comparative review of the status of related meteorological observation missions and of advanced sensing technologies.As one of the China Tianwen-1 Mission’s principal scientific payloads,the MCS contains four measurement sensors and one electronic processing unit that are specially designed to measure local temperature,pressure,wind,and sound on the Martian surface.The MCS’s measurement principles,technical schemes,ground calibration techniques,and adaptability evaluation to the Mars surface environment of MCS are introduced in details.The conclusion presents measurement performance specifications of the MCS,based on ground test results,that will provide guidance to future research based on data from the Tianwen-1 and later Mars missions. | YongQing Peng LeiBo Zhang ZhiGuo Cai ZhaoGang Wang HaiLong Jiao DongLi Wang XianTao Yang LianGuo Wang Xu Tan Feng Wang Jing Fang ZhouLu Sun HongLiang Feng XiaoRui Huang Yan Zhu Ming Chen LiangHai Li YanHua Li | 2020 | Earth and Planetary Physics2020，4，4： | 2 |
| 6 | Hydrothermal synthesis and visible-light photocatalytic activity of α-Fe 2 O 3 /TiO 2 composite hollow microspheres显示文摘 | Hua Tang Du Zhang Guogang Tang Xiaorui Ji Wenjing Li Changsheng Li Xiaofei Yang | 2013 | Ceramics International2013，，： | 2 |
| 7 | Overexpressing dominant-negative FGFR2-IIIb impedes lung branching morphogenesis in pigs显示文摘Genetic studies with mouse models have shown that fibroblast growth factor receptor 2-IIIb(FGFR2-IIIb)plays crucial roles in lung development and differentiation. To evaluate the effect of FGFR2-IIIb in pig lung development, we employed somatic cell nuclear transfer(SCNT) technology to generate transgenic pig fetuses overexpressing the transmembrane(dn FGFR2-IIIb-Tm) and soluble(dn FGFR2-IIIb-HFc) forms of the dominant-negative human FGFR2-IIIb driven by the human surfactant protein C(SP-C) promoter,which was specifically expressed in lung epithelia. Eight dn FGFR2-IIIb-Tm transgenic and twelve dn FGFR2-IIIb-HFc transgenic pig fetuses were collected from three and two recipient sows, respectively.Repression of FGFR2-IIIb in lung epithelia resulted in smaller lobes and retardation of alveolarization in both forms of dn FGFR2-IIIb transgenic fetuses. Moreover, the dn FGFR2-IIIb-HFc transgenic ones showed more deterioration in lung development. Our results demonstrate that disruption of FGFR2-IIIb signaling in the epithelium impedes normal branching and alveolarization in pig lungs, which is less severe than the results observed in transgenic mice. The dn FGFR2-IIIb transgenic pig is a good model for the studies of blastocyst complementation as well as the mechanisms of lung development and organogenesis. | Qin Chen Bin Fang Ying Wang Chu Li Xiaoxue Li Ronggen Wang Qiang Xiong Lining Zhang Yong Jin Manling Zhang Xiaorui Liu Lin Li Lisha Mou Rongfeng Li Haiyuan Yang Yifan Dai | 2018 | Journal of Genetics and Genomics2018，45，3： | 2 |
| 8 | A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex显示文摘Tuberous sclerosis complex(TSC)is a dominant genetic neurocutaneous syndrome characterized by multiple organ hamartomas.Although rodent models bearing a germline mutation in either TSC1 or TSC2 gene have been generated,they do not develop pathogenic lesions matching those seen in patients with TSC because of the significant differences between mice and humans,highlighting the need for an improved large animal model of TSC.Here,we successfully generate monoallelic TSC1-modified Bama miniature pigs using the CRISPR/Cas9 system along with somatic cell nuclear transfer(SCNT)technology.The expression of phosphorylated target ribosomal protein S6 is significantly enhanced in the piglets,indicating that disruption of a TSC1 allele activate the mechanistic target of rapamycin(mTOR)signaling pathway.Notably,differing from the mouse TSC models reported previously,the TSC1^(+/−)Bama miniature pig developed cardiac rhabdomyoma and subependymal nodules,resembling the major clinical features that occur in patients with TSC.These TSC1^(+/−)Bama miniature pigs could serve as valuable large animal models for further elucidation of the pathogenesis of TSC and the development of therapeutic strategies for TSC disease. | Xiaoxue Li Tingdong Hu Jiying Liu Bin Fang Xue Geng Qiang Xiong Lining Zhang Yong Jin Xiaorui Liu Lin Li Ying Wang Rongfeng Li Xiaochun Bai Haiyuan Yang Yifan Dai | 2020 | Journal of Genetics and Genomics2020，47，12： | 2 |
| 9 | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms显示文摘The ongoing coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has resulted in an unprecedented public health crisis,galvanizing a global effort for rapidly developing new therapeutic strategies effective against COVID-19.Human monoclonal antibodies(mAbs)are promising therapeutic molecules that can be used for the prevention or treatment of viral infectious diseases,including COVID-19.For instance,ZMapp^(TM),a cocktail consisting of three different mAbs targeting the Ebola glycoprotein is one of the most successful antibody-based therapeutic for treating infections caused by Ebola virus.1 Notably,this cocktail combines the best-performing neutralizing antibodies(NAbs)screened and developed using two separate approaches,one from humanized antibodies of origin and the other from human survivors. | Yao Sun Lei Wang Rui Feng Nan Wang Yuxi Wang Dandan Zhu Xiaorui Xing Peng Yang Yanjun Zhang Weimin Li Xiangxi Wang | 2021 | Cell Research2021，31，5： | 2 |
| 10 | Unsupervised hyperspectral unmixing based on robust nonnegative dictionary learning显示文摘Considering the sparsity of hyperspectral images(HSIs),dictionary learning frameworks have been widely used in the field of unsupervised spectral unmixing.However,it is worth mentioning here that existing dictionary learning method-based unmixing methods are found to be short of robustness in noisy contexts.To improve the performance,this study specifically puts forward a new unsupervised spectral unmixing solution.For the reason that the solution only functions in a condition that both endmembers and the abundances meet non-negative con-straints,a model is built to solve the unsupervised spectral un-mixing problem on the account of the dictionary learning me-thod.To raise the screening accuracy of final members,a new form of the target function is introduced into dictionary learning practice,which is conducive to the growing robustness of noisy HSI statistics.Then,by introducing the total variation(TV)terms into the proposed spectral unmixing based on robust nonnega-tive dictionary learning(RNDLSU),the context information under HSI space is to be cited as prior knowledge to compute the abundances when performing sparse unmixing operations.Ac-cording to the final results of the experiment,this method makes favorable performance under varying noise conditions,which is especially true under low signal to noise conditions. | LI Yang JIANG Bitao LI Xiaobin TIAN Jing SONG Xiaorui | 2022 | Journal of Systems Engineering and Electronics2022，33，2： | 1 |
| 11 | Effects of a reputation feedback system on an online consumer - to - consumer auction market 显示文摘 | Jian Yang Xiaorui Hu Han Zhang | 2007 | Decision Support Systems2007，，44： | 1 |
| 12 | An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk,local immunosuppression and tumor progression显示文摘Dissecting and understanding the cancer ecosystem,especially that around the tumor margins,which have strong implications for tumor cell infiltration and invasion,are essential for exploring the mechanisms of tumor metastasis and developing effective new treatments.Using a novel tumor border scanning and digitization model enabled by nanoscale resolution-SpaTial Enhanced REsolution Omics-sequencing(Stereo-seq),we identified a 500µm-wide zone centered around the tumor border in patients with liver cancer,referred to as“the invasive zone”.We detected strong immunosuppression,metabolic reprogramming,and severely damaged hepatocytes in this zone.We also identified a subpopulation of damaged hepatocytes with increased expression of serum amyloid A1 and A2(referred to collectively as SAAs)located close to the border on the paratumor side.Overexpression of CXCL6 in adjacent malignant cells could induce activation of the JAK-STAT3 pathway in nearby hepatocytes,which subsequently caused SAAs’overexpression in these hepatocytes.Furthermore,overexpression and secretion of SAAs by hepatocytes in the invasive zone could lead to the recruitment of macrophages and M2 polarization,further promoting local immunosuppression,potentially resulting in tumor progression.Clinical association analysis in additional five independent cohorts of patients with primary and secondary liver cancer(n=423)showed that patients with overexpression of SAAs in the invasive zone had a worse prognosis.Further in vivo experiments using mouse liver tumor models in situ confirmed that the knockdown of genes encoding SAAs in hepatocytes decreased macrophage accumulation around the tumor border and delayed tumor growth.The identification and characterization of a novel invasive zone in human cancer patients not only add an important layer of understanding regarding the mechanisms of tumor invasion and metastasis,but may also pave the way for developing novel therapeutic strategies for advanced liver cancer and other solid tumors. | Liang Wu Jiayan Yan Yinqi Bai Feiyu Chen Xuanxuan Zou Jiangshan Xu Ao Huang Liangzhen Hou Yu Zhong Zehua Jing Qichao Yu Xiaorui Zhou Zhifeng Jiang Chunqing Wang Mengnan Cheng Yuan Ji Yingyong Hou Rongkui Luo Qinqin Li Liang Wu Jianwen Cheng Pengxiang Wang Dezhen Guo Waidong Huang Junjie Lei Shang Liu Yizhen Yan Yiling Chen Sha Liao Yuxiang Li Haixiang Sun Na Yao Xiangyu Zhang Shiyu Zhang Xi Chen Yang Yu Yao Li Fengming Liu Zheng Wang Shaolai Zhou Huanming Yang Shuang Yang Xun Xu Longqi Liu Qiang Gao Zhaoyou Tang Xiangdong Wang Jian Wang Jia Fan Shiping Liu Xinrong Yang Ao Chen Jian Zhou | 2023 | Cell Research2023，33，8： | 1 |
| 13 | Effects of a reputation feedback system on an online consumer- to-consumer auction market显示文摘 | Jian Yang Xiaorui Hu Han Zhang | 2007 | Decision Support Systems2007，44，： | 1 |
| 14 | Deployment and Exploration of a Gas Storage Well Pattern Based on the Threshold Radius显示文摘To tackle the problem that wells that are deployed in a specific pattern based on the requirements of gas reservoir development are not suitable for gas storage,we have conducted concentrically circular injection and production simulation experiments for gas storage,discovered the existence of a threshold radius,denoted by Rt,and derived the expression for Rt.Based on the analysis and discussion results,we propose a strategy for deploying gas storage wells in specific patterns.The expression for Rt shows that it is affected by factors such as the gas storage gas production/injection time,the upper pressure limit,the lower pressure limit,the bottomhole flow pressure at the ends of injection and production,the and permeability.The analysis and discussion results show that the Rt of a gas storage facility is much smaller than the Rt for gas reservoir development.In the gas storage facilities in China,the Rt for gas production is less than the Rt for the gas injection,and Rt increases with the difference in the operating pressure and with permeability K.Based on the characteristics of Rt,we propose three suggestions for gas storage well pattern deployment:(1)calculate Rt according to the designed functions of the gas storage facility and deploy the well pattern according to Rt;(2)deploy sparser,large-wellbore patterns in high-permeability areas and denser,small-wellbore patterns in high-permeability areas;and(3)achieve the gas injection well pattern by new drilling,and the gas production well pattern through a combination of the gas injection well pattern and old wells.By assessing a gas storage facility with a perfect well pattern after a number of adjustments,we found that the Rt of the 12 wells calculated in this paper is basically close to the corresponding actual radius,which validates our method.The results of this study provide a methodological basis for well pattern deployment in new gas storage construction. | TANG Ligen ZHU Weiyao ZHU Huayin SUN Chunhui YANG Fenglai WANG Yan Li Xiaorui Li Haiming CHU Guangzhen WANG Jieming KONG Debin YUE Ming LIU Yuwei HUANG Kun | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 15 | Brassinosteroids regulate outer ovule integument growth in part via the control of INNER NO OUTER by BRASSINOZOLE‐RESISTANT family transcription factors显示文摘Brassinosteroids(BRs)play important roles in regulating plant reproductive processes.BR signaling or BR biosynthesis null mutants do not produce seeds under natural conditions,but the molecular mechanism underlying this infertility is poorly understood.In this study,we report that outer integument growth and embryo sac development were impaired in the ovules of the Arabidopsis thaliana BR receptor null mutant bri1-116.Gene expression and RNA-seq analyses showed that the expression of INNER NO OUTER(INO),an essential regulator of outer integument growth,was significantly reduced in the bri1-116 mutant.Increased INO expression due to overexpression or increased transcriptional activity of BRASSINAZOLE-RESISTANT 1(BZR1)in the mutant alleviated the outer integument growth defect in bri1-116 ovules,suggesting that BRs regulate outer integument growth partially via BZR1-mediated transcriptional regulation of INO.Meanwhile,INO expression in bzr-h,a null mutant for all BZR1 family genes,was barely detectable;and the outer integument of bzr-h ovules had much more severe growth defects than those of the bri1-116 mutant.Together,our findings establish a new role for BRs in regulating ovule development and suggest that BZR1 family transcription factors might regulate outer integument growth through both BRI1-dependent and BRI1-independent pathways. | Dandan Jia Lian-Ge Chen Guimin Yin Xiaorui Yang Zhihua Gao Yi Guo Yu Sun Wenqiang Tang | 2020 | Journal of Integrative Plant Biology2020，62，8： | 1 |
| 16 | Advancements in understanding mechanisms of hepatocellular carcinoma radiosensitivity:A comprehensive review显示文摘Primary liver cancer is a significant health problem worldwide.Hepatocellular carcinoma(HCC)is the main pathological type of primary liver cancer,accounting for 75%-85%of cases.In recent years,radiotherapy has become an emerging treatment for HCC and is effective for various stages of HCC.However,radiosensitivity of liver cancer cells has a significant effect on the efficacy of radiotherapy and is regulated by various factors.How to increase radiosensitivity and improve the therapeutic effects of radiotherapy require further exploration.This review summarizes the recent research progress on the mechanisms affecting sensitivity to radiotherapy,including epigenetics,transportation and metabolism,regulated cell death pathways,the microenvironment,and redox status,as well as the effect of nanoparticles on the radiosensitivity of liver cancer.It is expected to provide more effective strategies and methods for clinical treatment of liver cancer by radiotherapy. | Gaoyuan Yang Huamei Yan Yongchang Tang Feng Yuan Mingbo Cao Yupeng Ren Yuxuan Li Zhiwei He Xiaorui Su Zhicheng Yao Meihai Deng | 2023 | Chinese Journal of Cancer Research2023，35，3： | 1 |
| 17 | Variations of vinblastine accumulation and redox state affected by exogenous H2O2 in Catharanthus roseus (L.) G. Don显示文摘 | Zhonghua Tang Lei Yang Yuangang Zu Xiaorui Guo | 2009 | Plant Growth Regulation2009，，1： | 1 |
| 18 | Identification and characterization of two members of the FtsH gene family in maize (Zea mays L.)显示文摘 | Guidong Yue Xiaorui Hu Ying He Aifang Yang Juren Zhang | 2010 | Molecular Biology Reports2010，，2： | 1 |
| 19 | Fabrication and magnetic properties of Fe3O4 octahedra显示文摘 | Hu Chaoquan Gao Zhenghong Yang Xiaorui | 2006 | Chem Phys Lett2006，429，： | 1 |
| 20 | Effects of a Reputation Feedback System on an Online Consumer-to-consumer Auction Market 显示文摘 | YANG J XIAORUI H ZHANG H | 2007 | Decision Support Systems2007，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员