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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Seasonal Changes in Phytoplankton Biomass and Dominant Species in the Changjiang River Estuary and Adjacent Seas:General Trends Based on Field Survey Data 1959-2009显示文摘The characteristics of seasonal variation in phytoplankton biomass and dominant species in the Changjiang River Estuary and adjacent seas were discussed based on field investigation data from 1959 to 2009. The field data from 1981 to 2004 showed that the Chlorophyll-a concentration in surface seawater was between 0.4 and 8.5 μg dm-3. The seasonal changes generally presented a bimodal trend, with the biomass peaks occurring in May and August, and Chlorophyll-a concentration was the lowest in winter. Seasonal biomass changes were mainly controlled by temperature and nutrient levels. From the end of autumn to the next early spring, phytoplankton biomass was mainly influenced by temperature, and in other seasons, nutrient level(including the nutrient supply from the terrestrial runoffs) was the major influence factor. Field investigation data from 1959 to 2009 demonstrated that diatoms were the main phytoplankton in this area, and Skeletonema costatum, Pseudo-nitzschia pungens, Coscinodiscus oculus-iridis, Thalassinoema nitzschioides, Paralia sulcata, Chaetoceros lorenzianus, Chaetoceros curvisetus, and Prorocentrum donghaiense Lu were common dominant species. The seasonal variations in major dominant phytoplankton species presented the following trends: 1) Skeletonema(mainly S. costatum) was dominant throughout the year; and 2) seasonal succession trends were Coscinodiscus(spring) →Chaetoceros(summer and autumn) → Coscinodiscus(winter). The annual dominance of S. costatum was attributed to its environmental eurytopicity and long standing time in surface waters. The seasonal succession of Coscinodiscus and Chaetoceros was associated with the seasonal variation in water stability and nutrient level in this area. On the other hand, long-term field data also indicated obvious interannual variation of phytoplankton biomass and community structure in the Changjiang River Estuary and adjacent seas: average annual phytoplankton biomass and dinoflagellate proportion both presented increased trends during the 1950 s-2000 s. | YANG Shu HAN Xiurong ZHANG Chuansong SUN Baiye WANG Xiulin SHI Xiaoyong | 2014 | Journal of Ocean University of China2014，13，6： | 7 |
| 3 | One-pot synthesis of interconnected Pt95Co5 nanowires with enhanced electrocatalytic performance for methanol oxidation reaction显示文摘 | Qingqing Lu Litai Sun Xue Zhao Jianshe Huang Ce Han Xiurong Yang | 2018 | Nano Research2018，11，5： | 6 |
| 4 | Bone tissue regeneration:The role of finely tuned pore architecture of bioactive scaffolds before clinical translation显示文摘Spatial dimension of pores and interconnection in macroporous scaffolds is of particular importance in facilitating endogenous cell migration and bone tissue ingrowth.However,it is still a challenge to widely tune structure parameters of scaffolds by conventional methods because of inevitable pore geometrical deformation and poor pore interconnectivity.Here,the long-term in vivo biological performances of nonstoichiometric bioceramic scaffolds with different pore dimensions were assessed in critical-size femoral bone defect model.The 6%Mg-substituted wollastonite(CSi-Mg6)powders were prepared via wet-chemical precipitation and the scaffolds elaborately printed by ceramic stereolithography,displaying designed constant pore strut and tailorable pore height(200,320,450,600μm),were investigated thoroughly in the bone regeneration process.Together with detailed structural stability and mechanical properties were collaboratively outlined.BothμCT and histological analyses indicated that bone tissue ingrowth was retarded in 200μm scaffolds in the whole stage(2-16 weeks)but the 320μm scaffolds showed appreciable bone tissue in the center of porous constructs at 6-10 weeks and matured bone tissue were uniformly invaded in the whole pore networks at 16 weeks.Interestingly,the neo-tissue ingrowth was facilitated in the 450μm and 600μm scaffolds after 2 weeks and higher extent of bone regeneration and remodeling at the later stage.These new findings provide critical information on how engineered porous architecture impact bone regeneration in vivo.Simultaneously,this study shows important implications for optimizing the porous scaffolds design by advanced additive manufacture technique to match the clinical translation with high performance. | Ronghuan Wu Yifan Li Miaoda Shen Xianyan Yang Lei Zhang Xiurong Ke Guojing Yang Changyou Gao Zhongru Gou Sanzhong Xu | 2021 | Bioactive Materials2021，6，5： | 5 |
| 5 | RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes显示文摘There remains a significant gap in our quantitative understanding of crosstalk between apoptosis and necroptosis pathways.By employing the SWATH-MS technique,we quantified absolute amounts of up to thousands of proteins in dynamic assembling/de-assembling of TNF signaling complexes.Combining SWATH-MS-based network modeling and experimental validation,we found that when RIP1 level is below~1000 molecules/cell(mpc),the cell solely undergoes TRADD-dependent apoptosis.When RIP1 is above~1000 mpc,pro-caspase-8 and RIP3 are recruited to necrosome respectively with linear and nonlinear dependence on RIP1 amount,which well explains the co-occurrence of apoptosis and necroptosis and the paradoxical obser-vations that RIP1 is required for necroptosis but its increase down-regulates necroptosis.Higher amount of RIP1(>~46,000 mpc)suppresses apoptosis,leading to necroptosis alone.The relation between RIP1 level and occurrence of necroptosis or total cell death is biphasic.Our study provides a resource for encoding the com-plexity of TNF signaling and a quantitative picture how distinct dynamic interplay among proteins function as basis sets in signaling complexes,enabling RIP1 to play diverse roles in governing cell fate decisions. | Xiang Li Chuan-Qi Zhong Rui Wu Xiaozheng Xu Zhang-Hua Yang Shaowei Cai Xiurong Wu Xin Chen Zhiyong Yin Qingzu He Dianjie Li Fei Xu Yihua Yan Hong Qi Changchuan Xie Jianwei Shuai Jiahuai Han | 2021 | Protein & Cell2021，12，11： | 5 |
| 6 | 3D printing of Mg-substituted wollastonite reinforcing diopside porous bioceramics with enhanced mechanical and biological performances显示文摘Mechanical strength and its long-term stability of bioceramic scaffolds is still a problem to treat the osteonecrosis of the femoral head.Considering the long-term stability of diopside(DIO)ceramic but poor mechanical strength,we developed the DIO-based porous bioceramic composites via dilute magnesium substituted wollastonite reinforcing and three-dimensional(3D)printing.The experimental results showed that the secondary phase(i.e.10%magnesium substituting calcium silicate;CSM10)could readily improve the sintering property of the bioceramic composites(DIO/CSM10-x,x=0-30)with increasing the CSM10 content from 0%to 30%,and the presence of the CSM10 also improved the biomimetic apatite mineralization ability in the pore struts of the scaffolds.Furthermore,the flexible strength(12.5 -30 MPa)and compressive strength(14-37 MPa)of the 3D printed porous bioceramics remarkably increased with increasing CSM10 content,and the compressive strength of DIO/CSM10-30 showed a limited decay(from 37 MPa to 29 MPa)in the Tris buffer solution for a long time stage(8 weeks).These findings suggest that the new CSM10-reinforced diopside porous constructs possess excellent mechanical properties and can potentially be used to the clinic,especially for the treatment of osteonecrosis of the femoral head work as a bioceramic rod. | Dongshuang He Chen Zhuang Sanzhong Xu Xiurong Ke Xianyan Yang Lei Zhang Guojing Yang Xiaoyi Chen Xiaozhou Mou An Liu Zhongru Gou | 2016 | Bioactive Materials2016，1，1： | 5 |
| 7 | Analysis of the Transformation-induced Plasticity Effect during the Dynamic Deformation of High-manganese Steel显示文摘The transformation-induced plasticity(TRIP) effect and resistance characteristics to adiabatic shear failure at high strain rates of high-manganese steel were investigated by using scanning electron microscopy and electron backscattering diffraction. Results showed that the high-manganese steel exhibited excellent strain hardening effect and resistance to adiabatic shear failure because of the TRIP effect. The TRIP effect occurred during dynamic deformation and showed two distinct stages,namely,the smooth TRIP process before the formation of adiabatic shear band(ASB) and the inhibited TRIP process during further deformation. In the first stage,the martensitic transformation showed slight orientation dependence and weak variant selection,which promoted the TRIP effect. In the second stage,reverse martensitic transformation occurred. Adiabatic shear bands(ASBs) developed typical shear microtextures {111}<110>. In microtextures,two groups of fine grains are in a twin relationship and uniform distribution,which restrained the formation of holes and cracks within the ASBs and enhanced damage resistance after ASB formation. | Huizhen Wang Xiurong Sun Ping Yang Weimin Mao Li Meng | 2015 | Journal of Materials Science & Technology2015，31，2： | 4 |
| 8 | Hot deformation behavior and microstructure evolution of the laser solid formed TC4 titanium alloy显示文摘Hot compressive experiments of the laser solid formed(LSFed)TC4 titanium alloy were conducted at a wide temperature range of 650-950℃and strain rate of 0.01-10 s^(-1).The Arrheniustype constitutive models of the LSFed TC4 alloy were established at the temperature range of 800-950℃and of 650-800℃,respectively.The average relative error between the predicted stresses and experimental values in those two temperature ranges are 10.4%and 8.3%,respectively,indicating that the prediction models constructed in this paper are in a good agreement with experimental data.Processing maps were established by the principle of dynamic materials modeling on the basis of the data achieved from the hot compression experiments.The processing parameters corresponding to the stable and unstable regions of material deformation can be determined from the processing maps.The microstructure evolution of the stable and unstable regions of the samples after tests were observed.Finally,the effect of hot compressive parameters on the microstructure were investigated to research the dynamic recrystallization and the texture of the deformed LSFed TC4 alloy. | Xiawei YANG Yanying WANG Xiurong DONG Chong PENG Baijin JI Yaxin XU Wenya LI | 2021 | Chinese Journal of Aeronautics2021，34，5： | 3 |
| 9 | Generation Mechanism of Interfacial Layer and Its Effect on Fe-Cr-Ni/Al-Si-Cu-Ni-Mg Composite Performance显示文摘Fe-Cr-Ni/Al-Si-Cu-Ni-Mg composite was taken as the experimental material. The chemical composition of interfacial layer was tested. The generation mechanism and influence of interfacial layer on the composite were analyzed. The results indicated that the generation of interfacial layer is sensitive to temperature. Interfacial layer will generate rapidly when temperature reaches 500 ℃ or above. The interfacial layer is mainly composed of Al, Si, Cu, Fe, and Cr, element Ni distributes at the outward of the interfacial layer for the precipitate of Ni later than Si and Cu, and there is almost no diffusion of Ni during the solution treatment. During heat treatment process, unequal quantity changing of metal atom results in disperse or concentrated vacancies or holes near the matrix. The existence of interfacial layer will induce a decrease of compression strength and plasticity at room temperature and an increase of strength at higher temperature comparing with composite without interfacial layer. | 周灵展 YANG Liming ZHU Xiurong PENG Yinjiang | 2017 | Journal of Wuhan University of Technology(Materials Science)2017，32，5： | 2 |
| 10 | Capacitive detection of glucose using molecularly imprinted polymers显示文摘 | CHENG Zhiliang WANG Erkang YANG Xiurong | 2001 | Biosens Bioelectron2001，16，3： | 1 |
| 11 | A sensitive choline biosensor using Fe304 magnetic nanoparticles as peroxidase mimics显示文摘 | Zhang Zhanxia Wang Xiaolei Yang Xiurong | 2011 | Analyst2011，136，23： | 1 |
| 12 | Capillary electrophoresis with solid state electro chemiluminescence detector 显示文摘 | CAO Wei-dong JIA Jian-bo YANG Xiurong | 2002 | Electrophoresis2002，23，21： | 1 |
| 13 | Colorimetric biosensing of mercury(II) ion using unmodified gold nanoparticle probes and thrombin-binding aptamer显示文摘 | Yong Wang Fan Yang Xiurong Yang | 2010 | Biosensors and Bioelectronics2010，，8： | 1 |
| 14 | A sensitive method for the detection of catecholamine based on fluorescence quenching of CdSe nanocrystals显示文摘 | Ying ma Cheng Yang Nan li Xiurong Yang | 2005 | Talanta2005，67，： | 1 |
| 15 | Density functional theory study of W5 clusters显示文摘 | Zhang Xiurong Ding Xunlei Yang Jinlong | 2005 | International Journal of Modern Physics B2005，19，1517： | 1 |
| 16 | One saecharide sensor based on the complex of the boronic acid and the monosaccharide using electrochemical impedance spectroscopy 显示文摘 | Ma Ying Yang Xiurong | 2005 | J Electroanalyt Chem2005，58，2： | 1 |
| 17 | Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method 显示文摘 | Huang Haizhen Yang Xiurong | 2004 | Carbohydrate Research2004，339，15： | 1 |
| 18 | Affinity and Specificity of Levamlodipine-Human Serum Albumin Interactions: Insights into Its Carrier Function显示文摘 | Zuojia Liu Xiliang Zheng Xiurong Yang Erkang Wang Jin Wang | 2009 | Biophysical Journal2009，，10： | 1 |
| 19 | Densiy functional theory study of W5 clusters 显示文摘 | Zhang Xiurong Ding Xunlei Yang Jinrong | 2005 | International Journal of Modern Physic B2005，19，1517： | 1 |
| 20 | A sensitive method for the detection of proteins by high - efficiency fluorescence quenching显示文摘 | Ying Ma Haixin Bai Xiurong Yang | 2005 | Analyst2005，130，： | 1 |
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