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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 3 | Continued evolution of the Eurasian avian-like H1N1 swine influenza viruses in China显示文摘Animal influenza viruses continue to pose a threat to human public health. The Eurasian avian-like H1N1(EA H1N1) viruses are widespread in pigs throughout Europe and China and have caused human infections in several countries, indicating their pandemic potential. To carefully monitor the evolution of the EA H1N1 viruses in nature, we collected nasal swabs from 103,110pigs in 22 provinces in China between October 2013 and December 2019, and isolated 855 EA H1N1 viruses. Genomic analysis of 319 representative viruses revealed that these EA H1N1 viruses formed eight different genotypes through reassortment with viruses of other lineages circulating in humans and pigs, and two of these genotypes(G4 and G5) were widely distributed in pigs.Animal studies indicated that some strains have become highly pathogenic in mice and highly transmissible in ferrets via respiratory droplets. Moreover, two-thirds of the EA H1N1 viruses reacted poorly with ferret serum antibodies induced by the currently used H1N1 human influenza vaccine, suggesting that existing immunity may not prevent the transmission of the EA H1N1 viruses in humans. Our study reveals the evolution and pandemic potential of EA H1N1 viruses and provides important insights for future pandemic preparedness. | Fei Meng Yan Chen Zuchen Song Qiu Zhong Yijie Zhang Chuanling Qiao Cheng Yan Huihui Kong Liling Liu Chengjun Li Huanliang Yang Hualan Chen | 2023 | Science China(Life Sciences)2023，66，2： | 1 |
| 4 | Genetic Analysis and Improvement Strategies of Protein Content in Rice Seeds显示文摘Enhancing the nutritional quality of food crops is a way to improve human nutrition and health.Grain protein content(GPC)is an important nutritional quality trait for rice and many other crops.Therefore,it will be very significant to increase GPC and improve rice quality.This paper mainly reviewed the genetic studies GPC in rice,mapping and cloning of QTLs and genes associated with GPC.However,little is known about the molecular mechanism and gene function related to GPC in rice.Thus,here we put forward the genetic strategy by gene pyramiding or molecular marker assisted selection to improve GPC and nutritional quality in rice.This review could provide important information for genetic improvement of grain nutritional quality of rice. | Bo PENG Yanfang SUN Dongyan KONG Ruihua PANG Xiaohua SONG Huilong LI Lin LIU Xian-wen LI Jintao LI Qiying ZHOU Bin DUAN Huihui LIU Yuhan ZUO Yanlin HAO Shizhi SONG Hongyu YUAN | 2017 | Agricultural Biotechnology2017，6，4： | 1 |
| 5 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 6 | Multiple SiGe/Si layers epitaxy and SiGe selective etching for vertically stacked DRAM显示文摘Fifteen periods of Si/Si_(0.7)Ge_(0.3)multilayers(MLs)with various Si Ge thicknesses are grown on a 200 mm Si substrate using reduced pressure chemical vapor deposition(RPCVD).Several methods were utilized to characterize and analyze the ML structures.The high resolution transmission electron microscopy(HRTEM)results show that the ML structure with 20 nm Si_(0.7)Ge_(0.3)features the best crystal quality and no defects are observed.Stacked Si_(0.7)Ge_(0.3)ML structures etched by three different methods were carried out and compared,and the results show that they have different selectivities and morphologies.In this work,the fabrication process influences on Si/Si Ge MLs are studied and there are no significant effects on the Si layers,which are the channels in lateral gate all around field effect transistor(L-GAAFET)devices.For vertically-stacked dynamic random access memory(VS-DRAM),it is necessary to consider the dislocation caused by strain accumulation and stress release after the number of stacked layers exceeds the critical thickness.These results pave the way for the manufacture of high-performance multivertical-stacked Si nanowires,nanosheet L-GAAFETs,and DRAM devices. | Zhenzhen Kong Hongxiao Lin Hailing Wang Yanpeng Song Junjie Li Xiaomeng Liu Anyan Du Yuanhao Miao Yiwen Zhang Yuhui Ren Chen Li Jiahan Yu Jinbiao Liu Jingxiong Liu Qinzhu Zhang Jianfeng Gao Huihui Li Xiangsheng Wang Junfeng Li Henry HRadamson Chao Zhao Tianchun Ye Guilei Wang | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 7 | Effect of Disturbances on the Operation Process of a Methane-Fueled Free-Piston Engine Generator显示文摘In this paper,the effect of disturbances on the operation process of a methane-fueled free-piston engine generator(FPEG)was experimentally investigated.Four disturbance sources,namely step change of external load,mixture flow rate fluctuation,random misfire of a cylinder,and elastic collision,were identified and applied to the FPEG.The results showed that the FPEG successfully achieved a steady-state operation with load.The maximum instantaneous electric power of 127 W and the average effective electric power of 38.9 W were obtained.When an external load was instantaneously disconnected,the engine frequency increased from 26.7 Hz to 31.3 Hz.The fluctuation amplitudes of induced voltage,pressure and compression ratio were 18.9%,24.7%and 52.2%respectively in the disturbance.By contrast,when the external load was instantaneously connected,the corresponding values were 42.2%,31.3%and 64.3%respectively,indicating that the instantaneous external load connection had a greater disturbance impact on the FPEG operation stability.Despite encountering the step change of external load,the FPEG can still restore stable operation and show good anti-disturbance ability.Compared with increasing mixture flow rate,reducing the mixture flow rate has a greater disturbance impact on the engine operation stability.Although random misfire of a cylinder will cause remarkable fluctuations in piston displacement and cylinder pressure,the FPEG will not stop running,but continues to work as a single-piston engine.Minor collision event may adversely affect the stability of engine operation,but will not lead to the FPEG shutdown.However,serious collision event may lead to ignition failure and shutdown accident. | HUANG Fujun XIAO Huihui GUO Shuman WANG Lijun YANG Zhenzhong KONG Wenjun | 2023 | Journal of Thermal Science2023，32，2： | 0 |
| 8 | Self‐assembled fullerene(C60)‐pentacene superstructures for photodetectors显示文摘Fullerene assembling with specific donor molecules would yield multi-functional metamaterials via the collective behavior,wherein linear acenes are widely used as donor molecules to construct the charge‐transfer heterojunction structure with fullerene.However,they are generally prepared by vacuum deposition due to the insoluble property of high‐performance linear acenes molecules in common solvents,which makes the construction of fullerene with insoluble donor molecules still be a big challenge in the solution‐processed method.To this end,chemical modification provides an effective solution‐processed strategy to construct donor and acceptor systems.Here,the C60‐pentacene is assembled into controllable flower‐like superstructures by the surface grafting method.It is found that the nanofeatures of the microflowers could be regulated by temperature,resulting in dense‐flakes morphology at room temperature and loose flakes at high temperatures.Furthermore,the dense‐flakes microflowers structures with less mass but better crystalline structure exhibit better optoelectronic properties.Our results reveal an effective control on the nanofeatures of the self‐assembled fullerenes complex super-structures and their role for the optoelectronic performance,which may promote the exploring of fullerene superstructures as photodetectors. | Qin Tang Guangpu Zhang Bohong Jiang Deyang Ji Huihui Kong Kristina Riehemann Qingmin Ji Harald Fuchs | 2021 | SmartMat2021，2，1： | 0 |
| 9 | On-surface stereoconvergent synthesis, dimerization and hybridization of organocopper complexes显示文摘Despite the vital role of stereoconvergent synthesis in modern chemistry, the on-surface stereoconvergent synthesis of organometallic complexes involving transformation among several stereoisomers to one specific form has been few reported. By combination of high-resolution scanning tunneling microscopy(STM) imaging/manipulation and density functional theory(DFT) calculations, we have displayed the stereoconvergent synthesis of organocopper complexes via the Cu-alkene interaction and further dimerization into H-shaped motifs, in which two cis-forms and one trans-form are involved, and the specific adsorption configuration of one cis-form is revealed to be the key for such a synthesis. Furthermore, the generality of the dimerization of organocopper complexes has also been verified by codeposition of two similar molecular precursors, and the hybridized K-shaped motifs(made up of two kinds of organocopper complexes) have been successfully achieved. These findings may provide atomic-scale insights into the synthesis of specific stereoisomers in the fields of pharmaceuticals, biochemistry and organometallic chemistry. | Chi Zhang Qiang Sun Huihui Kong Chunxue Yuan Wei Xu | 2019 | Science China Chemistry2019，62，1： | 0 |
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