|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mapping wetland changes in China between 1978 and 2008显示文摘Four wetland maps for all China have been produced,based on Landsat and CBERS-02B remote sensing data between 1978 and 2008 (1978,1990,2000 and 2008).These maps were mainly developed by manual interpretation and validated by substantial field investigation in 2009.Based on these maps,we analyzed the 2008 wetland distribution in China and discussed wetland changes and their drivers over the past 30 years.(i) There were about 324097 km 2 of wetlands in 2008,for which inland marshes or swamps were the most common wetland type (35%),with lakes (26%) second.Most of the wetlands were in Heilongjiang,Inner Mongolia,Qinghai and Tibet,occupying about 55% of the national wetland area.(ii) From 1978 to 2008,China's wetland area continually and significantly decreased,by about 33% based on changes in the wetland map.This was in sharp contrast to the increase in artificial wetlands,which increased by about 122%.Inland marshes accounted for the main loss of total wetlands from 1978 to 2000.From 2000 through 2008,riverine and lacustrine wetlands constituted the main wetland loss.Fortunately however,the rate of wetland loss decreased from 5523 to 831 km 2 /a.(iii) The change ratio of lost natural wetlands (including inland and coastal wetlands) to non-wetlands has decreased slightly over the past 30 years.From 1978 to 1990,nearly all natural wetlands (98%) lost were transformed into non-wetlands.However,the ratio declined to 86% from 1990 to 2000,and to 77% from 2000 to 2008.(iv) All Chinese provinces were divided into three groups according to patterns of wetland changes,which could relate to the driving forces of such changes.Tibet was completely different from other provinces,as it was one representative example in which there was a net wetland increase,because of global warming and decreased human activity since 1990.Increased economic development caused considerable wetland loss in most eastern provinces,and artificial wetlands increased. | NIU ZhenGuo ZHANG HaiYing WANG XianWei YAO WenBo ZHOU DeMin ZHAO KuiYi ZHAO Hui LI NaNa HUANG HuaBing LI CongCong YANG Jun LIU CaiXia LIU Shuang WANG Lin LI Zhan YANG ZhenZhong QIAO Fei ZHENG YaoMin CHEN YanLei SHENG YongWei GAO XiaoHong ZHU WeiHong WANG WenQing WANG Hong WENG YongLing ZHUANG DaFang LIU JiYuan LUO ZhiCai CHENG Xiao GUO ZiQi GONG Peng | 2012 | Chinese Science Bulletin2012，57，22： | 51 |
| 2 | TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy显示文摘 | Chengyan Wang Xuming Tang Xiaomeng Sun Zhenchuan Miao Yaxin Lv Yanlei Yang Huidan Zhang Pengbo Zhang Yang Liu LiyingDu Yang Gao Ming Yin Mingxiao Ding Hongkui Deng | 2012 | Cell Research2012，22，1： | 17 |
| 3 | Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome显示文摘Accumulating evidence suggests that ketogenic diets(KDs)mediate the rise of circulating ketone bodies and exert a potential antiinflammatory effect;however,the consequences of this unique diet on colitis remain unknown.We performed a series of systematic studies using a dextran sulfate sodium(DSS)animal model of inflammatory colitis.Animals were fed with a KD,low-carbohydrate diet(LCD),or normal diet(ND).Germ-free mice were utilized in validation experiments.Colon tissues were analyzed by transcriptome sequencing,RT2 profiler PCR array,histopathology,and immunofluorescence.Serum samples were analyzed by metabolic assay kit.Fecal samples were analyzed by 16S rRNA gene sequencing,liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry.We observed that KD alleviated colitis by altering the gut microbiota and metabolites in a manner distinct from LCD.Quantitative diet experiments confirmed the unique impact of KD relative to LCD with a reproducible increase in Akkermansia,whereas the opposite was observed for Escherichia/Shigella.After colitis induction,the KD protected intestinal barrier function,and reduced the production of R0Ryt+CD3_group 3 innate lymphoid cells(ILC3s)and related inflammatory cytokines(IL-17a,IL-18,IL-22,Ccl4).Finally,fecal microbiota transplantation into germ-free mice revealed that the KD-mediated colitis inhibition and ILC3 regulation were dependent on the modification of gut microbiota.Taken together,our study presents a global view of microbiome-metabolomics changes that occur during KD colitis treatment,and identifies the regulation of gut microbiome and ILC3s as novel targets involving in IBD dietary therapy. | Cheng Kong Xuebing Yan Yongqiang Liu Linsheng Huang Yefei Zhu Jide He Renyuan Gao Matthew F.Kalady Ajay Goel Huanlong Qin Yanlei Ma | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 8 |
| 4 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 5 | MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling显示文摘To date,EV71 infection still poses a great challenge to the health of infants and young children.1 Much established evidence suggests that EV71 infection depends on a wide variety of host factors,including cell surface receptors for EV71 entry,innate immune response,miRNAs,and lncRNAs.2,3 It is thought that diverse signaling pathways are required for EV71 to escape the host immune response.4 Innate immunity serves as the first line of defense against pathogens.Tumor necrosis factor receptor-associated factor(TRAF)proteins are essential components of signaling pathways activated by Toll-like receptor(TLR)or RIG-I-like receptor(RLR)family members.TRAF3 is widely expressed by many cell types,including all nucleated immune cells,in which it plays many roles in the regulation of immune functions.5 TRAF3 plays a significant role in regulating the functions of B and T lymphocytes.TRAF3 is a highly versatile regulator that positively controls type I interferon and cytokine production through interferon regulatory factors(IRFs)and nuclear factor-κB(NF-κB).6 A recent study indicated that EV71-induced ubiquitin-specific protease 19(USP19)negatively regulates type I IFN signaling by targeting TRAF3. | Dong Li Shuaiyin Chen Weiguo Zhang Chao Zhang Tiantian Sun Yue Du Ronghua Ding Yanlei Gao Yuefei Jin Guangcai Duan | 2021 | Cellular & Molecular Immunology2021，18，5： | 2 |
| 6 | Influence of the surface modification of a filler on the properties of high- impact polystyrene composites显示文摘 | Cui Wenguang Gao Yanlei Wei Qing | 2009 | Journal of Applied Polymer Science2009，112，1： | 1 |
| 7 | Influence of the surface modification of a filler on the properties of high-impact polystyrene composites显示文摘 | Cui Wenguang Gao Yanlei Wei Qing | 2009 | Journal of Applied Polymer Science2009，112，： | 1 |
| 8 | Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB显示文摘 | Yongzhi Yang Yanlei Ma Chenzhang Shi Hongqi Chen Huizhen Zhang Niwei Chen Peng Zhang Feng Wang Jun Yang Jianjun Yang Qingchao Zhu Yong Liang Wen Wu Renyuan Gao Zhe Yang Yang Zou Huanlong Qin | 2013 | Biochemical and Biophysical Research Communications2013，，4： | 1 |
| 9 | Influence of the surface modification of a filler on the properties of highimpact polystyrene composites显示文摘 | Cui Wenguang Gao Yanlei Wei Qing | | 0，，01： | 1 |
| 10 | Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB显示文摘 | Yongzhi Yang Yanlei Ma Chenzhang Shi Hongqi Chen Huizhen Zhang Niwei Chen Peng Zhang Feng Wang Jun Yang Jianjun Yang Qingchao Zhu Yong Liang Wen Wu Renyuan Gao Zhe Yang Yang Zou Huanlong Qin | 2013 | Biochemical and Biophysical Research Communications2013，，4： | 1 |
| 11 | Influence of the surface modification of a filler on the properties of high- impact polystyrene composites显示文摘 | Cui Wenguang Gao Yanlei Wei Qing | 2009 | J Appl Polym Sci2009，112，： | 1 |
| 12 | The degradation of an epoxy adhesive in salt water显示文摘 | Yanlei Gao Jingping Xiong Sanping Zhang | 2005 | Advanced Material Reseach2005，，： | 1 |
| 13 | Investigations on dehydration processes of trisodium citrate hydrates显示文摘trisodium 的脱水过程柠檬酸盐(Na3C6H5O7 ) 水合物用 thermogravimetry (TG ) 被调查,微分扫描热量测定(DSC ) 和粉末 X 光检查衍射(PXRD ) 。trisodium 柠檬酸盐二水合物的脱水的温度在 430.99 K,这被发现。为 trisodium 柠檬酸盐五水合物,有一个二拍子的圆舞脱水过程, endothermal 山峰分别地出现在 337.23 K 和 433.83 K。在脱水过程的第一步期间, trisodium 柠檬酸盐五水合物的结构变成了 trisodium 柠檬酸盐二水合物的结构。另外,为 trisoidum 柠檬酸盐水合物的脱水的动力学也用 TG 数据被调查。根据 Ozawa 方程计算的脱水的激活精力,二水合物的脱水机制是不同的,这被发现。 | Junyan GAO Yanlei WANG Hongxun HAO | 2012 | Frontiers of Chemical Science and Engineering2012，6，3： | 0 |
| 14 | An Automatic Classification Grading of Spinach Seedlings Water Stress Based on N-MobileNetXt显示文摘To solve inefficient water stress classification of spinach seedlings under complex background,this study proposed an automatic classification method for the water stress level of spinach seedlings based on the N-MobileNetXt(NCAM+MobileNetXt)network.Firstly,this study recon-structed the Sandglass Block to effectively increase the model accuracy;secondly,this study introduced the group convolution module and a two-dimensional adaptive average pool,which can significantly compress the model parameters and enhance the model robustness separately;finally,this study innovatively proposed the Normalization-based Channel Attention Module(NCAM)to enhance the image features obviously.The experimental results showed that the classification accuracy of N-MobileNetXt model for spinach seedlings under the natural environment reached 90.35%,and the number of parameters was decreased by 66%compared with the original MobileNetXt model.The N-MobileNetXt model was superior to other net-work models such as ShuffleNet and GhostNet in terms of parameters and accuracy of identification.It can provide a theoretical basis and technical support for automatic irrigation. | Yanlei Xu Xue Cong Yuting Zhai Zhiyuan Gao Helong Yu | 2023 | Intelligent Automation & Soft Computing2023，37，9： | 0 |
| 15 | How the electron-deficient Cp ligand facilitates Rh-catalyzed annulations with alkynes显示文摘The mechanism and origin of the Cp^(X) ligand effects on Rh-catalyzed annulations with alkynes were inves-tigated using DFT calculations and the approach of energy decomposition analysis(EDA).The results reveal that the alkyne migratory insertion is the rate-determining step for the reactions with both acetanilide and 2-phenyl-2-propanol substrates. | Han Gao Lingfei Hu Yanlei Hu Xiangying Lv Yan-BoWu Gang Lu | 2022 | Organic Chemistry Frontiers2022，9，4： | 0 |
| 16 | Origins of regio-and stereoselectivity in Cu-catalyzed alkyne difunctionalization with CO_(2) and organoboranes显示文摘The mechanism and origins of regio-and stereoselectivities of Cu-catalyzed alkyne difunctionalization with CO_(2) and trialkyl boranes were computationally investigated.The results show that the vicinal addition to alkyne is disfavored due to the kinetical inertness of the alkyl copper intermediate.The favored geminal addition proceeds through the cationic Cu-mediated stereoselective 1,2-migration pathway.The energy decomposition analysis indicates that theσ)(πPauli repulsion is the dominant factor for controlling the stereoselectivity. | Lingfei Hu Han Gao Yanlei Hu Xiangying Lv Yan-Bo Wu Gang Lu | 2022 | Organic Chemistry Frontiers2022，9，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员